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Tag: synovitis

September 22, 2026

Seronegative Rheumatoid Arthritis: Can You Have RA With Negative RF and Anti-CCP?

Why negative antibody tests do not end an evaluation when swollen joints and other findings suggest inflammatory arthritis.

Yes, rheumatoid arthritis can occur with negative rheumatoid factor (RF) and anti-CCP antibody results. Clinicians use the term seronegative RA when the characteristic antibodies are not detected but the overall findings support the diagnosis. Negative […]

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