Men's Health Blood Tests

This hub is for adult men at any life stage who want a baseline wellness checksexual health/energy evaluationprostate & cardiometabolic risk assessment, fertility-related labsmedication/TRT monitoring, or follow-up after abnormal results. Core labs include testosterone (total/free SHBG), LH/FSH, prolactin, sensitive estradiol (LC/MS/MS)PSA (± % free)CBC (hemoglobin/hematocrit)lipids, ApoB, Non-HDL-C, Lp(a)A1c/fasting glucose ± insulinCMP/BMP (creatinine/eGFR, electrolytes; AST/ALT/ALP/GGT, bilirubin, albumin)uACRhs-CRPTSHVitamin DB12/folateiron studies (ferritin/iron/TIBC/TSAT)uric acid; and STI screens. Results guide screening cadencediagnostic workups (ED/hypogonadism, anemia, thyroid), risk reduction, and TRT monitoring—always with clinician guidance.


What It Tests

Men’s health testing helps you and your clinician:

  • Screen / Early detection: establish baseline CBC/CMPlipids/ApoB/Non-HDL-C/Lp(a)A1c/glucoseTSHVitamin DeGFR/uACR, ± hs-CRP for risk refinement.

  • Diagnose / Triage: evaluate low libido/ED, fatigue, mood or weight changes (hormones/thyroid), LUTS/prostate concerns (PSA), anemia or nutrient issues (CBC, iron/B12/folate), and infections/STIs.

  • Monitor: track response/safety for TRT (CBC/Hct, PSA, lipids, LFTs, ± estradiol), statins or other meds (lipids/LFTs), and chronic conditions (diabetes, kidney, liver, thyroid).

Interpretation principles

  • Pair symptoms serial labstrends > single values.

  • PSA levels can be altered by UTIrecent ejaculation/cyclingprostate manipulation, and 5-ARI therapy (which lowers PSA ~50%).

  • Consider kidney/liver context (eGFR/uACR and AST/ALT/ALP/GGT/bilirubin/albumin), especially for medication monitoring.


Key Tests

Test Also Called (Synonyms) What It Measures Typical Prep (fasting?) Specimen Turnaround Related Panels Use Type (Screen / Dx / Mon / Risk) Timing Notes / Caveats
Total Testosterone SHBG TT SHBG Androgen status & binding; informs free T calc Morning draw 7–10 a.m.; no fast Blood ~1–2 d Hormone Baseline Dx/Mon Repeat TT on different morning if low; high-dose biotin may interfere
Calculated Free Testosterone FT (calc) Biologically active fraction AM preferred Blood ~1–2 d Hormone Baseline Dx/Mon Interpret with TT SHBG and symptoms
LH / FSH Pituitary drive to testes No fast Blood ~1–2 d Hypogonadism Workup Dx Helps distinguish primary vs secondary hypogonadism
Prolactin PRL Hyperprolactinemia screen AM; avoid nipple stimulation/exercise Blood ~1–2 d Hormone Baseline Dx Repeat if borderline
Estradiol (sensitive) E2 (LC/MS/MS) Aromatization; gynecomastia/TRT context No fast Blood ~1–2 d TRT Monitoring Mon Prefer LC/MS/MS for accuracy at male levels
PSA (± % free) Prostate-specific antigen Prostate biomarker (not diagnostic) Avoid ejaculation/cycling 24–48 h; avoid testing during UTI Blood ~1–2 d Prostate Check Screen/Dx/Mon 5-ARI halves PSA; consider age/risk & shared decision
CBC (Hemoglobin/Hematocrit) Hgb/Hct Anemia/erythrocytosis No fast Blood Same–1 d TRT Monitoring Screen/Mon Monitor for erythrocytosis on TRT
Lipid Panel LDL-C/HDL-C/TG Atherogenic cholesterol Often 9–12 h fast Blood ~1–2 d Cardio Risk Screen/Risk Pair with ApoB/Non-HDL-C
Apolipoprotein B ApoB Atherogenic particle number No fast Blood ~1–2 d Cardio Risk Risk Strong risk marker; use with global risk
Lp(a) Lipoprotein(a) Genetic ASCVD risk No fast Blood ~1–2 d Cardio Risk Risk Usually once-in-lifetimemeasurement
Non-HDL-C Derived atherogenic cholesterol No fast Calc (lipids) Cardio Risk Risk Secondary lipid target
A1c / Fasting Glucose (± Insulin) Glycemia/IR A1c: no fast; glucose/insulin: fast per lab Blood ~1–2 d Diabetes Check Screen/Dx/Mon Trend with lifestyle/therapy
hs-CRP High-sens CRP Low-grade inflammation (CV risk) Test when well Blood ~1–2 d Cardio Risk Risk Avoid during/after illness or hard workouts
TSH (± Free T4) Thyroid function No fast Blood ~1–2 d Thyroid Check Screen/Dx Fatigue/mood/weight/ED context
Creatinine; uACR Kidney filtration & early damage No fast; first-morning urine ideal for uACR Blood/Urine ~1–2 d Kidney Risk Screen/Mon/Risk Use eGFR uACR together for risk
AST/ALT/ALP/; bilirubin; albumin LFTs Liver injury & function No fast (routine); avoid heavy exercise/alcohol 24–48 h Blood ~1–2 d LFT Panel Screen/Mon Med monitoring (e.g., statinsTRT)
Vitamin D (25-OH) Bone/muscle health No fast Blood ~1–2 d Bone Health Screen/Mon Seasonal variation possible
Ferritin Iron/TIBC/TSAT Iron status/overload No fast Blood ~1–2 d Anemia Workup Dx/Mon Interpret with CBC
Vitamin B12 ± Folate Macrocytic anemia/neuropathy No fast Blood ~1–2 d Anemia Workup Dx Meds can influence values
Uric Acid Gout/metabolic risk No fast Blood ~1–2 d Metabolic Risk Dx/Mon Diet/meds affect levels
STI Screens RPR/VDRL treponemal confirm, CT/NG NAAT ± Trich, HCV Ab RNA, HBV panel Infection screening First-catch urine for CT/NG; other tests as directed Blood/Urine/Swab ~1–3 d Sexual Health Screen/Dx Respect window periods; follow confirm algorithms

When to Test

  • Baseline men’s wellness (q1–3y or per clinician): CBC, CMP/BMP, lipids ApoB, A1c/glucose, TSH, ± Vitamin DeGFR/uACRhs-CRP.

  • Symptoms of low T/ED (low libido, fatigue, ED): two morning TT (± FT/SHBG) on different days; add LH/FSH, PRL, TSH, A1c/lipids.

  • Starting or monitoring TRT: TT/FTCBC (Hct/Hgb)PSA (age/risk-based), lipidsLFTs, ± sensitive E2—timing per clinician protocol.

  • Prostate concerns or shared-decision screening: PSA (avoid ejaculation/cycling; avoid during UTI; disclose 5-ARI use).

  • Cardiometabolic risk/family history: lipids/ApoB/Non-HDL-C/Lp(a)A1c/glucosehs-CRP, plus BP context.

  • Fertility evaluation (with clinician): TT/FT, LH/FSH, PRL, TSH (note: semen analysis is separate).

  • New sexual partner or exposure risk: STI screen per guidelines.

  • Medication monitoring (e.g., statins, isotretinoin, antifungals): LFTs, lipids, ± others per drug label.


How to Prepare

  • Fasting: Follow requisition; many lipid panels request 9–12 h fastingA1c does not require fasting.

  • Timing: Testosterone and prolactinmorning 7–10 a.m.

  • PSA: Avoid ejaculation and vigorous cycling for 24–48 hours; avoid testing during UTI or soon after prostate manipulation.

  • Supplements/meds: disclose biotinandrogens/5-ARIsstatinsglucocorticoidsthyroid meds.

  • Hydration/activity: maintain usual hydration; avoid very strenuous exercise immediately before the draw.

  • Consistency: for trend comparisons, use the same lab and similar conditions.


Interpreting Results

  • Testosterone: confirm low TT with a repeat morning test; interpret FT with SHBG; diagnose/manage only with a clinician.

  • PSA: not cancer by itself; use shared decision-making; repeat/confirm abnormal values and address confounders (UTI, ejaculation, cycling, manipulation, 5-ARI use).

  • CBC/Hct: high values on TRT may indicate erythrocytosis and require clinician management.

  • Lipids/ApoB/Lp(a): ApoB reflects atherogenic particle number; Lp(a) is largely genetic (often once-in-lifetime); combine with overall risk.

  • A1c/glucose/insulin: abnormal values suggest diabetes/insulin resistance—partner with your clinician.

  • Kidney/liver: use eGFR uACR together for kidney risk; AST/ALT/ALP/GGT/bilirubin/albumin for liver injury/function, especially on statins/TRT.

  • hs-CRP: measure when well; use alongside lipids to refine CV risk.

  • No performance-enhancement or illicit steroid guidance. No dosing advice provided.


Related Conditions

  • Erectile Dysfunction & Low Testosterone

  • Prostate Health & Cancer Screening 

  • Cardiometabolic Risk (Heart & Lipids) 

  • Diabetes & Insulin Resistance 

  • Thyroid & Energy 

  • Kidney & Liver Health 

  • Sexual Health & STI Screening 

  • Bone Health 


Bundles & Panels


FAQs

Do I need to fast for men’s health labs?
Often yes for lipids (9–12 h); A1c does not require fasting. Follow your requisition.

When is the best time to check testosterone?
Morning (7–10 a.m.). If low, repeat on a different morning before concluding it’s low.

Total vs free testosterone—which matters?
They complement each other. Interpret FT alongside TT SHBG and symptoms.

Does TRT always raise PSA or hematocrit?
It can raise hematocrit (erythrocytosis) and affect PSA; monitor per clinician protocol.

Can sex or cycling affect PSA?
Yes—avoid ejaculation and vigorous cycling for 24–48 h before testing.

What is ApoB and why is it important?
ApoB reflects the number of atherogenic particles and helps refine cardiovascular risk.

Should every man test Lp(a)?
one-time measurement is often useful, especially with family history of premature ASCVD.

Do I need an STI screen if I have no symptoms?
Screening is risk-based; discuss frequency with your clinician.

Why measure eGFR uACR together?
They refine kidney risk better than either alone (function early damage).

Can biotin or supplements affect results?
High-dose biotin can interfere with some immunoassays. Tell the lab about supplements/meds.


References

  • Endocrine Society — Evaluation/management of male hypogonadism and TRT monitoring

  • AUA / USPSTF — Prostate cancer screening and PSA shared decision-making

  • ACC/AHA — Lipid risk assessment; ApoB & Lp(a) context; hs-CRP risk refinement

  • ADA — A1c/glucose testing and cardiometabolic risk guidance

  • KDIGO / NKF — Kidney risk using eGFR uACR

  • AASLD — Liver enzyme/function interpretation

  • CDC — STI/HIV/HBV/HCV screening recommendations

  • Mayo Clinic Laboratories / ARUP Consult — Test utilization & method notes

Last reviewed: September 2025 by Ulta Lab Tests Medical Review Team

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Around 24% of men aged 30-79 will have low testosterone. However, this is usually accompanied by symptoms, such as reduced sex drive and loss of lean muscle mass; the chances of being asymptomatic increase with age. After the age of 50, there’s a 47.9% chance of showing no symptoms whatsoever.

Low testosterone is just one issue that can affect men’s health. Others include prostate issues, low fertility, hormone imbalances, and a low sex drive.

Luckily, men’s health tests can detect these issues early and help you make the right treatment decision.

Keep on reading to discover more information about the various men’s health lab tests, including how they work and what they can test for!

What is Men’s Health?

Men’s health is about much more than avoiding illness or health issues. It’s about keeping your overall health (physical, psychological, and emotional) as high as it can be, along with your sense of social wellbeing. Understanding your health is essential to living your best life!

Men’s health can decline with age due to various factors, including lifestyle and social changes, physical changes, and hormonal changes. With age, men become more at risk of developing:

  • Alcohol problems
  • Depression (and suicidal thoughts/intentions)
  • Cardiovascular and respiratory issues
  • Accident-prone behavior
  • Kidney disease

Men are 32% less likely than women to consult a doctor about a medical issue, meaning they have an increased risk of remaining undetected and untreated medical problems. This is particularly true of male-specific problems, such as male libido, erectile dysfunction, prostate health, low testosterone levels, etc.

Men’s health tests can help detect these issues early without the need to consult a doctor.

Understanding Men’s Health Tests

Men’s health tests typically involve three stages: screening, diagnosis, and monitoring. Screening detects potential issues before symptoms appear. The information from the screening is then used to make a diagnosis. Finally, monitoring is about keeping track of the problem and measuring whether it’s improving.

Men’s health tests can come in many different forms. One of the most common is a physical exam, where a medical professional examines areas of the body to search for common problems based on the individual’s age group, lifestyle, and any existing symptoms. This can include a basic prostate health test.

Some tests are non-invasive, like a body weight and body mass index (BMI) calculation or a blood pressure reading. These allow professionals to create a basic health profile.

Others require samples to be taken, such as a Complete Blood Count (CBC), also known as a Full Blood Count, where blood-circulating cells are examined to determine the individual’s overall health. Platelets, white blood cells, red blood cells, hemoglobin concentrations, and others are examined to check for issues such as infections or certain diseases.

The Comprehensive Metabolic Panel (CMP) is another blood test that measures 21 different biomarkers to determine the functionality of a range of metabolic processes. It can highlight any issues with the liver, kidneys, sugar (glucose) levels, fluid balance, or electrolyte balance.

Men’s Health Lab Tests

Additionally, more specific men’s health lab tests can be carried out to detect hormone levels (such as testosterone), various types of cancer (including prostate cancer, testicular cancer, colon cancers), and other medical conditions.

These are some of the big worries you may be facing as a man. If so, getting your blood pressure checked won’t be enough to tell you about erectile dysfunction (ED) or low male libido.

But if you’re not showing any symptoms, combining various tests can create a detailed and complete men’s health profile.

Some important elements you want any men’s health lab test to include are:

Irregular levels in these areas can have an impact on fertility, prostate health, hormone levels, arousal, and other men’s health issues. As many of these issues can arise without symptoms, lab tests offer you invaluable insight.

Frequently Asked Questions

You may have a lot of questions about men’s health tests. These are some answers to the most common questions.

How Long Does It Take To Get Results?

Once you’ve given a blood sample, it will be sent to one of our National CLIA certified labs for analysis. You can usually expect results within 3 business days. More complex tests can take 7-10 business days, but you’ll be notified by e-mail when your results are ready to be viewed.

How Do I Get Started?

To get started, select the test that best fits your needs. This may be based on age group, sex, existing symptoms, or area of worry. Some of our tests cast a wider net to give you a better overview of your health.

During the purchasing process, you’ll be able to select one of our 2,100 approved patient centers where your blood will be collected. Then, all you need to do is wait for the results of your men’s health profile.

How Do I Prepare For My Test?

Some tests will require you to fast before having blood drawn. How long you should fast for and what you can or can’t consume will be made clear to you in the instructions that accompany each test.

Why Use Ulta Lab Tests?

Results are accurate, reliable, secure, and confidential. The test results provided give you the information and knowledge necessary to regain control of your health and make informed decisions. You don’t need health insurance or a physician’s referral for these tests. You’ll get affordable pricing with a 100% satisfaction guarantee.

Ready for a Test?

Men’s health tests can be a truly valuable and worthwhile way of understanding your health and getting ahead of many potential male issues. And men’s health lab tests can offer a deeper level of understanding of what’s going on inside your body and how it is performing.

Take control of your health today and order your men’s health tests from Ulta Lab Tests!