Prostate Blood Testing and health information

The prostate blood test screens for prostate cancer in men without symptoms and measures the amount of prostate-specific antigen (PSA) in your blood produced by both cancerous and noncancerous tissue in the prostate. Ulta Lab Tests provides reliable blood work and secure testing, so order today!

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In men over 50 years with total PSA between 4.0 and 10.0 ng/mL, the percent (%) free PSA gives an estimate of the probability of cancer. In these circumstances the measurement of the % free PSA may aid in avoiding unnecessary biopsies. Elevated levels of Prostate Specific Antigen (PSA) have been associated with benign and malignant prostatic disorders. Studies indicate that in men 50 years or older measurement of PSA is a useful addition to the digital rectal exam in the early detection of prostate cancer. In addition, PSA decreases to undetectable levels following complete resection of the tumor and may rise again with recurrent disease or persist with residual disease. Thus, PSA levels may be of assistance in the management of prostate cancer patients.

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Elevated serum PSA concentrations have been reported in men with prostate cancer, benign prostatic hypertrophy, and inflammatory conditions of the prostate.

Elevated serum PSA concentrations have been reported in men with prostate cancer, benign prostatic hypertrophy, and inflammatory conditions of the prostate.

The BUN/Creatinine ratio is useful in the differential diagnosis of acute or chronic renal disease. Reduced renal perfusion, e.g., congestive heart failure, or recent onset of urinary tract obstruction will result in an increase in BUN/Creatinine ratio. Increased urea formation also results in an increase in the ratio, e.g., gastrointestinal bleeding, trauma, etc. When there is decreased formation of urea as seen in liver disease, there is a decrease in the BUN/Creatinine ratio. In most cases of chronic renal disease the ratio remains relatively normal.

Comprehensive Metabolic Panel

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Serum creatinine is useful in the evaluation of kidney function and in monitoring renal dialysis. A serum creatinine result within the reference range does not rule out renal function impairment: serum creatinine is not sensitive to early renal damage since it varies with age, gender and ethnic background. The impact of these variables can be reduced by an estimation of the glomerular filtration rate using an equation that includes serum creatinine, age and gender.

IMPORTANT - Culture, Urine, Routine #395 can Reflex to additional testing and charges, detailed below, if Culture is positive.

If culture is positive, CPT code(s): 87088 (each isolate) will be added with an additional charge.  Identification will be performed at an additional charge (CPT code(s): 87077 or 87140 or 87143 or 87147 or 87149).

Antibiotic susceptibilities are only performed when appropriate (CPT code(s): 87181 or 87184 or 87185 or 87186).

  • ORG ID 1. $ 12.45 
  • ORG ID 2. $ 23.95 
  • PRESUMPTIVE ID 1. $ 12.45 
  • PRESUMPTIVE ID 2. $ 23.95 
  • SUSC-1  $14.95 
  • SUSC-2  $28.95

Clinical Significance

Culture, Urine, Routine - This culture is designed to quantitate the growth of significant bacteria when collected by the Clean Catch Guidelines or from indwelling catheters.  Quantitative culturing of urine is an established tool to differentiate significant bacteruria from contamination introduced during voiding. This test has a reference range of less than 1,000 bacteria per mL. More than 95% of Urinary Tract Infections (UTI) are attributed to a single organism. Infecting organisms are usually present at greater that 100,000 per mL, but a lower density may be clinically important. In cases of UTI where more than one organism is present, the predominant organism is usually significant and others are probably urethral or collection contaminants. When multiple organisms are isolated from patients with indwelling catheters, UTI is doubtful and colonization likely.

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Urea is the principle waste product of protein catabolism. BUN is most commonly measured in the diagnosis and treatment of certain renal and metabolic diseases. Increased BUN concentration may result from increased production of urea due to (1) diet or excessive destruction of cellular proteins as occurs in massive infection and fevers, (2) reduced renal perfusion resulting from dehydration or heart failure, (3) nearly all types of kidney disease, and (4) mechanical obstruction to urine excretion such as is caused by stones, tumors, infection, or stricture. Decreased urea levels are less frequent and occur primarily in advanced liver disease and in overhydration

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Dipstick urinalysis is important in accessing the chemical constituents in the urine and the relationship to various disease states. Microscopic examination helps to detect the presence of cells and other formed elements.

NOTE: Only measurable biomarkers will be reported.

Benign Prostatic Hypertrophy, or as popularly referred to as Benign Prostatic Hyperplasia, is a non-cancerous and progressive enlargement of the prostate. Typically, the prostate is just a small gland about walnut-sized, and it encircles the male’s urethra as well as nourishes sperm using a fluid it produces. Other seminal vesicles fluid and this fluid are what make up semen. 

The prostate volume increases with BPH, which in turn puts pressure on the urethra, resulting in urine stream slowdown, a weak interrupted stream, hesitancy when urinating, and, at times, urine dribbling at the end of a flow. When urine is unable to flow via the urethra freely, the bladder’s muscular wall thickens and becomes super-sensitive to urine. This, in turn, culminates in frequent urination. As time goes by, the muscles of the bladder become weak and no longer have the power of contracting with enough force for emptying the bladder. 

Remnant urine in the bladder only increases the chances of developing bladder stones or a urinary tract infection. In other fatal situations involving BPH, urine might back up and damage the kidneys. In rare circumstances BPH may hinder a person from urinating altogether, which is something that should be addressed immediately. BPH and its treatments may also impact sexual functionality, such as painful ejaculation and erectile dysfunction. 

The originating cause of Benign Prostatic Hyperplasia has not yet been found. But some studies suggest that the balance of sex hormones changes as men age are a contributing factor. Some males may have a BPH genetic predisposition. It’s estimated that 50% of men under 60 years who have undergone surgical intervention fall under this category. 

Risk factors 

Here are some of the risk factors associated with Benign Prostatic Hyperplasia: 

  • Age 40 or older 
  • Family history of BPH (father or brother) 
  • Ethnic background – As compared to African American men and white men, BPH is less common in Asian men; African American men have a higher chance of developing BPH at a younger age compared to white men 
  • History of chronic health issues like obesity, heart disease, and type 2 diabetes, 
  • Lack of physical exercise 
  • Erectile dysfunction 

Signs and Symptoms 

The severity and type of signs and symptoms experienced vary from person to person and over time. For most of the men, BPH never goes beyond minor to moderate, while for others, it may pose a massive challenge to the quality of life. 

The American Urological Association has made a questionnaire intending to assist men in evaluating the seriousness of their urinary symptoms and keeping track of the treatment’s effectiveness. This is an internationally adopted questionnaire referred to as the International Prostate Symptom Score (IPSS). 

Questions on IPSS investigate the following: 

  • Incomplete bladder emptying 
  • Frequency of urination 
  • Stopping and starting the urine stream 
  • Urinary urgency 
  • Weak urine stream 
  • Straining to urinate 
  • Waking up at night to urinate (nocturia) 
  • The man’s perceived quality of life 

As men get older, BPH becomes a common condition. It’s estimated that 20% of males between 41 and 50 years are likely to experience BPH. The National Association for Continence suggests that around 50% of males will experience some form of BPH by the time they are 60, and almost up to 90% of them will be affected by 85 years old. Though BPH doesn’t necessarily cause prostate cancer, it can usually be found together. 

Laboratory tests 

Prostate-specific antigen (PSA) – This is a blood test that measures PSA levels, a protein made by prostate cells found in the blood. It may be increased in males who have prostate cancer and for those with BPH, though only slightly elevated. When assessing the lab results, the physician should take into consideration the PSA concentration in blood and the man’s prostate size. 

Urinalysis – a group of tests used for looking for urinary tract infection (UTI) signs or blood in the urine (hematuria) 

Urine culture – another test used to look for an indication of a UTI. 

Electrolytes, blood urea nitrogen (BUN) and creatinine – blood tests to assess kidney function