Low T and Testosterone Replacement Therapy (TRT)

Men receiving TRT therapy should regularly monitor their blood for adverse effects and treatment effectiveness, including testosterone measurements, complete blood count to measure hematocrit, and prostate-specific antigen testing.  Ulta Lab Tests provides reliable blood work for testosterone therapy and secure testing, so order today

Are you a man who is receiving testosterone replacement therapy (TRT)?

Testosterone replacement therapy (TRT) is a treatment option for men who have low testosterone. TRT can help treat symptoms such as fatigue, decreased libido, and erectile dysfunction. It can also boost muscle mass and bone density. However, if you receive testosterone replacement therapy (TRT), you should regularly monitor your blood for adverse effects and treatment effectiveness. Ulta Lab Tests provides TRT lab testing with affordable and accurate blood work, so order today!

Are you looking for a way to monitor your hormone levels?

Testosterone Replacement Therapy (TRT) Panel is a set of comprehensive blood tests ordered to monitor hormonal balance, key biomarkers, and organ function. The panel includes all of the following tests in one order: total testosterone, free testosterone, estradiol, sex hormone binding globulin (SHBG), albumin, IGF-1 (Insulin-like Growth Factor 1), thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), luteinizing hormone (LH). This panel will help you monitor and track your TRT and identify biomarkers that are out of balance.

If you are considering starting TRT or have already begun it but want to ensure everything is working correctly, then our lab panels and tests will give you peace of mind. You’ll know exactly what’s happening with your hormones and how they affect other important markers like cholesterol and liver enzymes. The results from this test can also be used as a baseline when testing future changes in your health status so that you can see how well the treatment has been working over time. With this information, you’ll be able to work with your doctor to adjust any medications or supplements accordingly so that they work at their best potential without causing side effects or complications down the road. We strongly recommend having these tests run every 1 to 3 months while on TRT to have an accurate picture of where things stand at all times so that you can maintain optimal health.

If you want to learn more about Low T and Testosterone Replacement Therapy (TRT) and the lab tests that can help you, click on the title of the articles below.

We provide confidential and secure testing with fast results, so order lab tests from us today!    Our friendly staff will help you every step of the way to make sure that your experience with us is easy and convenient. You can even track the changes in your biomarkers online! It’s never been easier to get the information you need about your health. Your satisfaction is guaranteed when you choose Ulta Lab Tests as your lab provider of choice for all things related to TRT testing and monitoring. 

Take charge of your health today with Ulta Lab Tests. We offer discounted lab tests online with 2,000 locations nationally with quick, convenient local testing and results from Quest Diagnostics in just 24 to 48 hours for most tests. Ulta Lab Tests provides the accurate test results you need to keep your health on track. Plus, our low prices are guaranteed - so you can get the quality care you deserve without breaking the bank. Test quickly and confidently with Ulta Lab Tests!


Name Matches

Low Testosterone [LOW T] Lab Test Review Panel -  Tested biomarkers include:

  • CBC (includes Differential and Platelets)
  • Comprehensive Metabolic Panel (CMP)
  • Cortisol, A.M.
  • DHEA Sulfate, Immunoassay
  • Estradiol
  • Ferritin
  • Hemoglobin A1c (HgbA1C)
  • Homocysteine
  • hs-CRP
  • LH
  • Lipid Panel With Ratios
  • Progesterone, Immunoassay
  • PSA Total
  • QuestAssureD™ 25-Hydroxyvitamin D (D2, D3), LC/MS/MS
  • T3 Reverse (RT3), LC/MS/MS
  • T3, Free
  • T4, Free
  • Testosterone, Total And Free And Sex Hormone Binding Globulin
  • Thyroid Peroxidase and Thyroglobulin Antibodies
  • TSH

Testosterone Replacement Package - Tested biomarkers include:

  • Testosterone
    free testosterone
    bioavailable testosterone
    sex hormone binding globulin
  • Estradiol
  • Complete Blood Count – White Blood Cell Count – Red Blood Cell Count – Hemoglobin – Hematocrit – MCV – MCH – MCHC – RDW – Platelet Count – MPV – Neutrophils – Lymphocytes – Monocytes – Eosinophils – Basophils

Proper testosterone replacement requires monitoring the testosterone levels and the complete blood count, estradiol levels, and prostate-specific antigen (PSA).  Lack of testosterone can cause loss of skeletal muscle, accumulation of belly fat, fatigue, irritability and mood disturbance, loss of libido, and decreased energy and endurance. 


 Testosterone Replacement Package II - Tested biomarkers include:

  • Testosterone
    free testosterone
    bioavailable testosterone
    sex hormone binding globulin
  • Estradiol
  • Prostate Specific Antigen (PSA)
  • Complete Blood Count – White Blood Cell Count – Red Blood Cell Count – Hemoglobin – Hematocrit – MCV – MCH – MCHC – RDW – Platelet Count – MPV – Neutrophils – Lymphocytes – Monocytes – Eosinophils – Basophils

Proper testosterone replacement requires monitoring the testosterone levels and the complete blood count, estradiol levels, and prostate-specific antigen (PSA).  Lack of testosterone can cause loss of skeletal muscle, accumulation of belly fat, fatigue, irritability and mood disturbance, loss of libido, and decreased energy and endurance. 


Testosterone Replacement Therapy (TRT) Plus Blood Test Panel

  • CBC (includes Differential and Platelets)
  • Comprehensive Metabolic Panel (CMP)
  • Estradiol
  • PSA, Free and Total
  • Testosterone, Total And Free And Sex Hormone Binding Globulin

  • CBC (includes Differential and Platelets)
  • Comprehensive Metabolic Panel (CMP)
  • Estradiol, Ultrasensitive LC/MS/MS
  • Lipid Panel
  • PSA Total
  • Sex Hormone Binding Globulin (SHBG)
  • Testosterone, Free, Bioavailable and Total, MS
  • TSH

TESTOSTERONE REPLACEMENT THERAPY (TRT) BLOOD TEST PANEL 

  • CBC (includes Differential and Platelets) 
  • PSA Total
  • Testosterone, Free (Dialysis) and Total 

Important: Stop biotin consumption at least 72 hours prior to the collection.


  • CBC (includes Differential and Platelets) [ 6399 ]
  • Comprehensive Metabolic Panel (CMP) [ 10231 ]
  • Estradiol [ 4021 ]
  • FSH and LH [ 7137 ]
  • Growth Hormone (GH) [ 521 ]
  • IGF-I, LC/MS [ 16293 ]
  • IGF Binding Protein 3 [ 34458 ]
  • PSA, Free and Total [ 31348 ]
  • Testosterone, Free (Dialysis) and Total LC/MS/MS [ 36170 ]
  • Vitamin D, 25-Hydroxy, Total, Immunoassay [ 17306 ]

Helpful in assessing testicular function in prepubescent hypogonadal males and in managing hirsutism, virilization in females

This is an uncapped test. Reference ranges above 1100 ng/dL can be reported with a quantitative result.


Testosterone circulates almost entirely bound to transport proteins: normally less than 1% is free. Measurement of Free Testosterone may be useful when disturbances in Sex Hormone Binding Globulin (SHBG) are suspected such as when patients are obese or have excessive estrogen. Testosterone measurements are used to assess erectile dysfunction, infertility, gynecomastia, and osteoporosis and to assess hormone replacement therapy.


This test is useful in the differential diagnosis of male hypogonadism. For males 18 years of age and older only. Pediatric and Female patients will need to order Testosterone, Total, MS #15983.

Due to changes in testosterone levels throughout the day, two morning (8:00-10:00 a.m.) specimens obtained on different days are recommended by The Endocrine Society for screening.

Please note: If Testosterone, Total, Males (Adult) Only #873 is ordered for a pediatric or female patient, the lab will automatically change the test to and charge for Testosterone, Total, MS #15983.

This test can report a value up to 3000 ng/dL. any number >3000 will be stated as >3000.


Helpful in assessing testicular function in males and managing hirsutism, virilization in females.

  • CBC (includes Differential and Platelets) [ 6399 ]
  • Comprehensive Metabolic Panel (CMP) [ 10231 ]
  • Estradiol [ 4021 ]
  • FSH and LH [ 7137 ]
  • Growth Hormone (GH) [ 521 ]
  • IGF-I, LC/MS [ 16293 ]
  • IGF Binding Protein 3 [ 34458 ]
  • PSA, Free and Total [ 31348 ]
  • Testosterone, Free (Dialysis) and Total LC/MS/MS [ 36170 ]
  • Vitamin D, 25-Hydroxy, Total, Immunoassay [ 17306 ]

17-hydroxyprogesterone is elevated in patients with congenital adrenal hyperplasia (CAH). CAH is a group of autosomal recessive diseases characterized by a deficiency of cortisol and an excess of ACTH concentration. 17-hydroxyprogesterone is also useful in monitoring cortisol replacement therapy and in evaluating infertility and adrenal and ovarian neoplasms.

Androstenedione is useful when evaluating patients with androgen excess and managing patients with Congenital Adrenal Hyperplasia (CAH).

AMH/MIS may be used in the detection of the onset of puberty in males, in the differential diagnosis of intersex disorders, cryptorchidism, or anorchidism and in the evaluation of male gonadal function in all ages.


C-Reactive Protein Cardiac (hs CRP) Useful in predicting risk for cardiovascular disease.


A Complete Blood Count (CBC) Panel is used as a screening test for various disease states including anemia, leukemia, and inflammatory processes.

A CBC blood test includes the following biomarkers: WBC, RBC, Hemoglobin, Hematocrit, MCV, MCH, MCHC, RDW, Platelet count, Neutrophils, Lymphs, Monocytes, Eos, Basos, Neutrophils (Absolute), Lymphs (Absolute), Monocytes(Absolute), Eos (Absolute), Basos (Absolute), Immature Granulocytes, Immature Grans (Abs)

NOTE: Only measurable biomarkers will be reported.

Reflex Parameters for Manual Slide Review
  Less than  Greater Than 
WBC  1.5 x 10^3  30.0 x 10^3 
Hemoglobin  7.0 g/dL  19.0 g/dL 
Hematocrit  None  75%
Platelet  100 x 10^3  800 x 10^3 
MCV  70 fL  115 fL 
MCH  22 pg  37 pg 
MCHC  29 g/dL  36.5 g/dL 
RBC  None  8.00 x 10^6 
RDW  None  21.5
Relative Neutrophil %  1% or ABNC <500  None 
Relative Lymphocyte %  1% 70%
Relative Monocyte %  None  25%
Eosinophil  None  35%
Basophil  None  3.50%
     
Platelet  <75 with no flags,
>100 and <130 with platelet clump flag present,
>1000 
Instrument Flags Variant lymphs, blasts,
immature neutrophils,  nRBC’s, abnormal platelets,
giant platelets, potential interference
     
The automated differential averages 6000+ cells. If none of the above parameters are met, the results are released without manual review.
CBC Reflex Pathway

Step 1 - The slide review is performed by qualified Laboratory staff and includes:

  • Confirmation of differential percentages
  • WBC and platelet estimates, when needed
  • Full review of RBC morphology
  • Comments for toxic changes, RBC inclusions, abnormal lymphs, and other
  • significant findings
  • If the differential percentages agree with the automated counts and no abnormal cells are seen, the automated differential is reported with appropriate comments

Step 2 - The slide review is performed by qualified Laboratory staff and includes: If any of the following are seen on the slide review, Laboratory staff will perform a manual differential:

  • Immature, abnormal, or toxic cells
  • nRBC’s
  • Disagreement with automated differential
  • Atypical/abnormal RBC morphology
  • Any RBC inclusions

Step 3 If any of the following are seen on the manual differential, a Pathologist will review the slide:

  • WBC<1,500 with abnormal cells noted
  • Blasts/immature cells, hairy cell lymphs, or megakaryocytes
  • New abnormal lymphocytes or monocytes
  • Variant or atypical lymphs >15%
  • Blood parasites
  • RBC morphology with 3+ spherocytes, RBC inclusions, suspect Hgb-C,
  • crystals, Pappenheimer bodies or bizarre morphology
  • nRBC’s

Comprehensive Metabolic Panel


Most Popular

Cortisol is increased in Cushing's Disease and decreased in Addison's Disease (adrenal insufficiency). Patient needs to have the specimen collected between 7 a.m.-9 a.m.


DHEA-S is the sulfated form of DHEA and is the major androgen produced by the adrenal glands. This test is used in the differential diagnosis of hirsute or virilized female patients and for the diagnosis of isolated premature adrenarche and adrenal tumors. About 10% of hirsute women with Polycystic Ovarian Syndrome (PCOS) have elevated DHEA-S but normal levels of other androgens.


Most Popular

Measuring the circulating levels of estradiol is important for assessing the ovarian function and monitoring follicular development for assisted reproduction protocols. Estradiol plays an essential role throughout the human menstrual cycle. Elevated estradiol levels in females may also result from primary or secondary ovarian hyperfunction. Very high estradiol levels are found during the induction of ovulation for assisted reproduction therapy or in pregnancy. Decreased estradiol levels in females may result from either lack of ovarian synthesis (primary ovarian hypofunction and menopause) or a lesion in the hypothalamus-pituitary axis (secondary ovarian hypofunction). Elevated estradiol levels in males may be due to increased aromatization of androgens, resulting in gynecomastia.

IMPORTANT - Note this Estradiol test is not for children that have yet to start their menstrual cycle.  If this test is ordered for a child that has yet to begin their menstrual cycle Quest Diagnostics labs will substitute in Estradiol, Ultrasensitive LC/MS/MS - #30289 at an additional charge of $34



Most Popular

Useful in the diagnosis of hypochromic, microcytic anemias. Decreased in iron deficiency anemia and increased in iron overload.


This test is useful in the differential diagnosis of pituitary and gonadal insufficiency and in children with precocious puberty.

Most Popular
FSH and LH are secreted by the anterior pituitary in response to gonadotropin-releasing hormone (GNRH) secreted by the hypothalamus. In both males and females, FSH and LH secretion is regulated by a balance of positive and negative feedback mechanisms involving the hypothalamic-pituitary axis, the reproductive organs, and the pituitary and sex steroid hormones. FSH and LH play a critical role in maintaining the normal function of the male and female reproductive systems. Abnormal FSH levels with corresponding increased or decreased levels of LH, estrogens, progesterone, and testosterone are associated with a number of pathological conditions. Increased FSH levels are associated with menopause and primary ovarian hypofunction in females and primary hypogonadism in males. Decreased levels of FSH are associated with primary ovarian hyper-function in females and primary hypergonadism in males. Normal or decreased levels of FSH are associated with polycystic ovary disease in females. In males, LH is also called interstitial cell-stimulating hormone (ICSH). Abnormal LH levels with corresponding increased or decreased levels of FSH, estrogens, progesterone, and testosterone are associated with a number of pathological conditions. Increased LH levels are associated with menopause, primary ovarian hypofunction, and polycystic ovary disease in females and primary hypo-gonadism in males. Decreased LH levels are associated with primary ovarian hyperfunction in females and primary hyper-gonadism in males.


Are you feeling tired all the time? Have you noticed that your hair is not growing as usual? Are you struggling with your weight?

If the answer is yes, you may have low testosterone levels. This is also known as low T. It affects around 2 out of every 100 men in America. Thankfully effective therapies are available to help.

Let's take a look at testosterone replacement therapy tests, and how you can get them.

What Is the Low T and Testosterone Replacement Therapy (TRT)?

Low T is a condition in which there is a low level of the male sex hormone testosterone in the body. For a man to be diagnosed with low testosterone, it needs to be lower than 300 nanograms per deciliter (ng/dL).

Testosterone naturally exists in the body in two forms - free and testosterone that is attached to other proteins. The free testosterone circulates and having too little is linked to the symptoms mentioned at the outset. 

Testosterone replacement therapy (TRT) is hormone therapy for treating low testosterone. Testosterone can be administered in a variety of ways. These include patches, gels, injections, and even implants. Make sure you get an accurate diagnosis before starting any of these treatments.

Risk Factors for Low T and Testosterone Replacement Therapy (TRT)

There are many different reasons men develop low T. Some risk factors include:

  • Injury to the testicles
  • Chemotherapy
  • Metabolic disorders
  • Medications and illicit drug use
  • Alcohol
  • HIV/AIDS
  • Kidney failure
  • Obesity
  • Aging

If you have symptoms and know your lifestyle is not healthy, this is a good place to start.

Signs and Symptoms of Low T and Testosterone Replacement Therapy (TRT)

Symptoms of low testosterone vary from person to person. Older men are more likely to experience low testosterone than younger men. The following are common symptoms:

  • Low libido (sex drive)
  • Difficulty attaining or maintaining erections
  • Malaise
  • Feelings of depression
  • Concentration or memory problems
  • Feeling tired all the time
  • Irritability
  • Loss of muscle tone and strength

If low testosterone levels persist, there can be consequences. These include thinning of the bones, hair loss, infertility, and even breast development.

If you're experiencing any of these symptoms, it's good to get an understanding of where your baseline testosterone levels are at. 

Lab Tests for Low T and Testosterone Replacement Therapy (TRT)

The first step is to take lab tests to determine whether you are suffering from low testosterone levels. This will help your doctor decide whether or not you need treatment and the type of treatment you need.

A pre-TRT blood test will examine at least the following areas:

A complete blood count is important. It will help your doctor to see whether other factors could be contributing to your symptoms. The PSA level is important as elevated levels may indicate the presence of prostate cancer

Your doctor may advise taking your total testosterone level at two different times on two different days. Ideally, do this between 7-10 am. That's because naturally testosterone levels rise and fall in the body.

Later in the day, levels are naturally lower. So, to gain a baseline for diagnostic purposes, two tests early in the day give a clearer picture. 

Once treatment for low T has started, you will need follow-up testosterone replacement therapy lab tests. These are usually done after 4 to 6 weeks. 

The two most common lab panels ordered by practitioners are the Testosterone Replacement Therapy (TRT) Panel and the Testosterone Replacement Therapy (TRT) Plus Panel that monitor the hormonal balance, and key biomarkers and organ function that can be affected with TRT.

Frequently Asked Questions

People have a range of questions about low T and testosterone replacement therapy tests. Some of their most common are:

What are normal testosterone levels?

A normal testosterone level for a healthy man is normally considered to be more than 300 nanograms per deciliter (ng/dL). If you have a level that is lower than this, your doctor may diagnose low testosterone and recommend treatment.

What are the benefits of testosterone replacement therapy (TRT)?

The benefits of TRT include increased libido, increased muscle mass, and increased energy. Many men also report improvements in their mood and energy levels.

What are the risks of TRT?

The risks include having to take testosterone treatment long-term. If your body does not respond by naturally making more, it's possible that you will need to keep taking treatment.

What is the cost of TRT?

The cost of TRT will depend on a number of factors, including the dosage needed and whether this is covered by your insurance. Costs vary widely between $20 and $1000 per month. 

TRT should be prescribed by a physician. This ensures that you are getting the correct dose, and your condition is being monitored.

It's important to remember that testosterone replacement is not a wonder drug. You should only take it on medical advice and it's only for men who have a diagnosis of low T.

If you're experiencing a low mood, lack of energy, and a loss of interest in sex, take a look at your lifestyle. How are your diet and sleep? Do you exercise regularly? You can improve some of these issues through lifestyle changes rather than hormone therapy.

Benefits of Low T and Testosterone Replacement Therapy Tests With Ulta Lab Tests

The only way to diagnose low T is through testosterone replacement therapy tests. Never embark on treatment for low testosterone without thorough testing and sound medical advice. If you do have low T though, TRT could help you get your mojo back.

Ulta Lab Tests offers TRT testing that is highly accurate and reliable so you can make informed decisions about your health.

  • Secure and Confidential Results
  • No Insurance or Referral Needed
  • Affordable Pricing including Doctor's Order
  • 100% Satisfaction Guarantee

Order your low T and testosterone replacement therapy (TRT) lab test today. Your results will be provided to you securely and confidentially online in 24 to 48 hours for most tests.

Take charge of your health and track your progress with Ulta Lab Tests.