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August 27, 2026

High A1C Levels Without Diabetes: Is It Possible

A high A1C can reflect true dysglycemia, red-blood-cell changes, or an assay interference. The right next step is confirmation—not assuming that you do or do not have diabetes.

It is possible to have a high A1C without an established diabetes diagnosis. An A1C of 5.7% to 6.4% is in the prediabetes range. An A1C of 6.5% or higher meets a diabetes diagnostic threshold, […]

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August 27, 2026

1,5-Anhydroglucitol (1,5-AG): When A1C May Miss Recent Glucose Spikes

An evidence-based guide to the narrow role of 1,5-AG as an adjunct—not a replacement—for A1C, plasma glucose, home monitoring, or continuous glucose data.

A1C and 1,5-anhydroglucitol do not compete for the same job. A1C is an established test for diabetes screening, diagnosis, and longer-term monitoring. 1,5-anhydroglucitol (1,5-AG) is a narrower adjunctive marker that may fall when glucose has […]

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July 22, 2026

Understanding Vitamin D Tests: Forms, Results, and Health Roles

How 25-Hydroxyvitamin D, Vitamin D2/D3, and Calcitriol Tests Differ—and When Each Test May Be Useful

Vitamin D tests do not all measure the same form of vitamin D. Learn which blood test is generally used to evaluate vitamin D status, when D2 and D3 fractions may add context, and why […]

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