Thyroid Health

Thyroid Health Testing and health information

Be proactive in your thyroid health with Ulta Lab Tests. Check out our guide to thyroid diseases and thyroid lab testing, and be proactive in your thyroid testing to monitor and track your health.

SEE BELOW THE LIST OF TESTS FOR MORE INFORMATION ABOUT  Thyroid Dissorders and Thyroid Lab Testing


Name Matches

Tests in the The Top 10 Thyroid Lab Tests to Ask for and How to Interpret Them

  • T3 Reverse (RT3), LC/MS/MS [ 90963 ]
  • T3 Total [ 859 ]
  • T3, Free [ 34429 ]
  • T4 (Thyroxine), Total [ 867 ]
  • T4, Free [ 866 ]
  • Thyroid Peroxidase and Thyroglobulin Antibodies [ 7260 ]
  • TRAb (TSH Receptor Binding Antibody) [ 5738 ]
  • TSH [ 899 ]
  • TSI (Thyroid Stimulating Immunoglobulin) [ 30551 ]
     

  • Ferritin 457
  • Glucose 483
  • Hemoglobin A1c (HgbA1C) 496
  • Insulin 561
  • Iron and Total Iron Binding Capacity (TIBC) 7573
  • Lipid Panel 7600
  • QuestAssureD™ 25-Hydroxyvitamin D (D2, D3), LC/MS/MS 92888
  • Selenium 5507
  • T3, Free 34429
  • T4, Free 866
  • Thyroid Peroxidase and Thyroglobulin Antibodies 7260
  • TSH 899
  • Vitamin B12 (Cobalamin) 927
     

Thyroid Foundation Panel + Thyroid Panel Add-On

  • Ferritin 457
  • Glucose 483
  • Hemoglobin A1c (HgbA1C) 496
  • Insulin 561
  • Iron and Total Iron Binding Capacity (TIBC) 7573
  • Lipid Panel 7600
  • QuestAssureD™ 25-Hydroxyvitamin D (D2, D3), LC/MS/MS 92888
  • Selenium 5507
  • T3, Free 34429
  • T4, Free 866
  • Thyroid Peroxidase and Thyroglobulin Antibodies 7260
  • TSH 899
  • Vitamin B12 (Cobalamin) 927

Thyroid Add-On Panel

  • Reverse T3
  • Comprehensive Metabolic Panel (CMP)
  • CBC (includes Differential and Platelets)

The Thyroid Nation – Thyroid Foundation Panel is a comprehensive panel of 15 tests from Quest Diagnostics that provides a thorough assessment of thyroid function and metabolism.

The panel includes tests for Thyroid Stimulating Hormone (TSH), free T3, free T4, Thyroid Peroxidase Antibodies, and Antithyroglobulin Antibodies. Additionally, the panel measures fasting glucose, hemoglobin A1c, and nutrients such as vitamin D, vitamin B12, serum ferritin, iron, zinc, and magnesium. The panel also includes a Complete Blood Count (CBC) and a Comprehensive Metabolic Panel (CMP) to evaluate liver and kidney function, electrolytes, and protein stores.

The Thyroid Nation – Thyroid Foundation Panel is an invaluable tool for evaluating thyroid function and metabolism. It can help to identify the cause of symptoms such as fatigue, weight gain, hair loss, and depression. Additionally, the panel can help to assess the risk of developing thyroid disease or cancer. The panel is also useful for monitoring the progress of treatment and for assessing the need for changes in medication or other therapies.

If you have been experiencing any of the above symptoms, or if you are concerned about your risk of developing thyroid disease, we recommend that you schedule an appointment with your healthcare provider to discuss the Thyroid Nation – Thyroid Foundation Panel.

Thyroid symptoms can be difficult to manage on your own. The Thyroid Nation – Thyroid Foundation Panel can help you and your healthcare practitioner to develop a personalized treatment plan that is right for you.

The Thyroid Nation – Thyroid Foundation Panel contains the following 15 Quest Diagnostics tests.

  • CBC (includes Differential and Platelets)
  • Comprehensive Metabolic Panel (CMP)
  • Ferritin
  • Hemoglobin A1c (HgbA1C)
  • Iron and Total Iron Binding Capacity (TIBC)
  • Lipid Panel with Ratios
  • Magnesium
  • QuestAssureD™ 25-Hydroxyvitamin D (D2, D3), LC/MS/MS
  • T3 Reverse (RT3), LC/MS/MS
  • T3, Free
  • T4, Free
  • Thyroid Peroxidase and Thyroglobulin Antibodies
  • TSH
  • Vitamin B12 (Cobalamin)
  • Zinc

Thyroid
TSH • free T3 • free T4 • Thyroid Peroxidase Antibodies • Antithyroglobulin Antibodies

Metabolism
Fasting Glucose • Hemoglobin A1c

Nutrients
Vitamin D • Vitamin B12 • Serum Ferritin • Iron & Total Iron Binding Capacity (TIBC) • Zinc • Magnesium

Core Tests
CMP (liver and kidney function, electrolytes, and protein stores) • CBC (complete blood count)


The Thyroid Health - Basic lab panel contains four tests that measure six biomarkers to assess thyroid function. The first test, T4 (Thyroxine), Total, measures the amount of thyroxine in the blood. The second test, T4, Free, measures the amount of free thyroxine in the blood. The third test, TSH, measures the level of thyroid stimulating hormone in the blood. The fourth test, T3 Uptake, measures the uptake of triiodothyronine by the thyroid gland. This panel is important for assessing thyroid function and can help diagnose thyroid disorders.

The Thyroid Health - Basic lab panel includes:

  • Thyroid-Stimulating Hormone (TSH)
  • T3 Uptake
  • T4 (Thyroxine), Total
  • T4, Free

Consider the Thyroid Health - Advanced Lab panel, which includes additional T3 Total T3, Free, T3 Reverse (RT3), Thyroid Peroxidase, and Thyroglobulin Antibodies tests for a more comprehensive picture of your thyroid health. Consider the Thyroid Health - Comprehensive lab panel, which includes all of the tests in the advanced panel as well as TBG (Thyroxine Binding Globulin) and TSI (Thyroid Stimulating Immunoglobulin).


The Thyroid Health - Basic Plus lab panel contains 6 tests with 8 biomarkers to give you an overview of your thyroid health. This panel includes all of the Thyroid Health - Basic tests, plus T3 Total and T3, Free. You can make informed decisions about your health and take steps to improve your thyroid function with this information.

The Thyroid Health - Basic Plus lab panel includes:

  • Thyroid-Stimulating Hormone (TSH)
  • T3 Uptake
  • T4 (Thyroxine), Total
  • T4, Free
  • T3 Total
  • T3, Free

What does the thyroid do?
A butterfly-shaped gland called the thyroid is found at the front of the neck. Thyroid hormones are created by the thyroid and released into the bloodstream, where they are carried by the blood to all bodily tissues. Thyroid hormones help the body use energy, keep its temperature steady, and keep the brain, heart, muscles, and other organs working properly.

What do thyroid hormones do?
Thyroid hormones are a big part of how your metabolism (how your body uses energy) works. They also change how the body grows and develops, how hot or cold it gets, and how sensitive it is to other hormones.

Thyroid hormone levels can change during the day, so it's important to check them several times over time to get a clear picture of what's going on.

The Thyroid Health - Basic Plus lab panel can help you understand your thyroid function and identify potential problems so you can take steps to improve your health.

For a more thorough understanding of your thyroid health, consider the Thyroid Health - Advanced Lab panel with additional T3 Reverse (RT3), Thyroid Peroxidase, and Thyroglobulin Antibodies tests. And for the most complete thyroid panel, consider the Thyroid Health - Comprehensive lab panel with all the tests in the advanced panel plus TBG (Thyroxine Binding Globulin) and TSI (Thyroid Stimulating Immunoglobulin).


The Thyroid Health - Advanced lab panel contains all of the tests in the Thyroid Health - Basic and Thyroid Health - Basic Plus lab panels, plus TBG (Thyroxine Binding Globulin) and TSI (Thyroid Stimulating Immunoglobulin). This advanced thyroid panel thoroughly assesses your thyroid function and can help identify both hypothyroidism and hyperthyroidism.

The Thyroid Health - Advanced lab panel includes the following tests:

  • T3 Uptake
  • T4 (Thyroxine), Total
  • T4, Free
  • TSH
  • T3 Total
  • T3, Free
  • T3 Reverse (RT3), LC/MS/MS
  • Thyroid Peroxidase and Thyroglobulin Antibodies

This advanced thyroid panel gives you a complete look at how your thyroid works and can help determine if you have hypothyroidism or hyperthyroidism. If you are experiencing symptoms such as fatigue, weight gain or loss, hair loss, mood swings, or difficulty concentrating, this panel can help determine if your thyroid is the root cause.

This panel can also be used to evaluate your response to treatment and optimize your medication levels if you have been diagnosed with a thyroid condition. Regular monitoring of your thyroid function is especially important if you are pregnant or planning to become pregnant, as thyroid disorders can have serious consequences for both mother and child.

The Thyroid Health - Advanced lab panel is easy to order, and results are typically available within 1-2 business days. Ordering this panel through Ulta Lab Tests is convenient, affordable, and confidential - there are no doctor's orders required, and all of our tests are conducted by Quest Diagnostics laboratories. Order online today!


Are you looking for a comprehensive thyroid health lab panel?
Look no further than the Thyroid Health - Comprehensive lab panel from Ulta Lab Tests. This panel is designed to provide the most comprehensive assessment of thyroid function available and includes 10 thyroid tests with 13 biomarkers, providing you with valuable insights into your thyroid function.

The Thyroid Health - Comprehensive panel tests for T3 Reverse (RT3), T3 Total, T3 Uptake, T3, Free, T4 (Thyroxine), Total, T4, Free, TBG (Thyroxine Binding Globulin), Thyroid Peroxidase and Thyroglobulin Antibodies, TSH, and TSI (Thyroid Stimulating Immunoglobulin). With this wealth of information at your fingertips, you'll be able to understand better how your thyroid is functioning and identify any potential areas of concern.

This panel is an invaluable tool for diagnosing and managing thyroid disorders. It is an invaluable tool for practitioners who want to get a complete picture of their patients' thyroid health. Order the Thyroid Health - Comprehensive panel today!

What's included in Thyroid Health - Comprehensive panel?

The Thyroid Health - Comprehensive panel includes the following tests:

  • T3 Reverse (RT3), LC/MS/MS
  • T3 Total
  • T3 Uptake
  • T3, Free
  • T4 (Thyroxine), Total
  • T4, Free
  • TBG (Thyroxine Binding Globulin)
  • Thyroid Peroxidase and Thyroglobulin Antibodies
  • TSH
  • TSI (Thyroid Stimulating Immunoglobulin)

What are the early warning signs of thyroid disease?

There are a number of potential early warning signs of thyroid problems, including:

  • Fatigue
  • Weight gain or difficulty losing weight
  • Cold intolerance
  • Constipation
  • Dry skin
  • Hair loss
  • Muscle aches and pains
  • Irregular menstrual cycles
  • Depression
  • Anxiety
  • Brain fog

If you have any of these symptoms, you should order the Ulta Lab Tests Thyroid Health panel to receive a complete picture of your thyroid health.

Does the thyroid blood test require fasting?

No, the Thyroid Health - Comprehensive panel does not require fasting.

What do the results of the Thyroid Health - Comprehensive panel mean?

The results of the Thyroid Health - Comprehensive panel can provide valuable insights into your thyroid function. T3 Reverse (RT3), T3 Total, T3 Uptake, and T3, Free are all measures of the amount of T3 hormone in your blood. T4 (Thyroxine), Total, and T4, Free are measures of the amount of T4 hormone in your blood. TBG (Thyroxine Binding Globulin) is a measure of the amount of thyroxine-binding globulin in your blood. This protein binds to thyroid hormones and affects the amount of thyroid hormone available to the body. Thyroid Peroxidase and Thyroglobulin Antibodies are measures of the levels of these antibodies in your blood. High levels of these antibodies can indicate an autoimmune thyroid disorder such as Hashimoto's disease or Graves' disease. TSH is a measure of the amount of thyroid-stimulating hormone in your blood. This hormone signals the thyroid gland to produce more thyroid hormones. TSI (Thyroid Stimulating Immunoglobulin) is a measure of the level of this immunoglobulin in your blood. High levels of TSI can indicate Graves' disease, an autoimmune disorder that causes the overproduction of thyroid hormones.

The results of the Thyroid Health - Comprehensive panel can help you, and your practitioner better understand your thyroid function and identify any potential areas of concern. If you have any questions regarding your results, please speak with your practitioner.

What can I do to support thyroid health?

There are a number of things you can do to support thyroid health, including:

  • Regular physical activity 
  • Eating a nutritious diet rich in fresh fruits and vegetables 
  • Stress reduction 
  • Avoiding exposure to environmental toxins 
  • Making sure you consume enough iodine

If you suspect you may have a thyroid problem, the first step is to talk to order the Thyroid Health panel or other tests to help identify any potential problems. Once your thyroid function has been assessed, you can work with your practitioner to develop a treatment plan that is right for you. If you have an autoimmune thyroid disorder, there are a number of things you can do to help manage your condition and keep your thyroid function in check. These include following a healthy diet, getting regular exercise, and managing stress. 


  • T4, Free [ 866 ]
  • TSH [ 899 ]

  • T3 Total [ 859 ]
  • T3, Free [ 34429 ]
  • T4 (Thyroxine), Total [ 867 ]
  • T4, Free [ 866 ]
  • TSH [ 899 ]

  • T3 Reverse (RT3), LC/MS/MS [ 90963 ]
  • T3 Total [ 859 ]
  • T3, Free [ 34429 ]
  • T4 (Thyroxine), Total [ 867 ]
  • T4, Free [ 866 ]
  • Thyroid Peroxidase and Thyroglobulin Antibodies [ 7260 ]
  • TSH [ 899 ]

  • T3 Reverse (RT3), LC/MS/MS [ 90963 ]
  • T3 Total [ 859 ]
  • T3, Free [ 34429 ]
  • T4 (Thyroxine), Total [ 867 ]
  • T4, Free [ 866 ]
  • Thyroid Peroxidase and Thyroglobulin Antibodies [ 7260 ]
  • TRAb (TSH Receptor Binding Antibody) [ 38683 ]
  • TSH [ 899 ]
  • TSI (Thyroid Stimulating Immunoglobulin) [ 30551 ]
     

Description: A CBC or Complete Blood Count with Differential and Platelets test is a blood test that measures many important features of your blood’s red and white blood cells and platelets. A Complete Blood Count can be used to evaluate your overall health and detect a wide variety of conditions such as infection, anemia, and leukemia. It also looks at other important aspects of your blood health such as hemoglobin, which carries oxygen. 

Also Known As: CBC test, Complete Blood Count Test, Total Blood Count Test, CBC with Differential and Platelets test, Hemogram test  

Collection Method: Blood Draw 

Specimen Type: Whole Blood 

Test Preparation: No preparation required 

When is a Complete Blood Count test ordered?  

The complete blood count (CBC) is an extremely common test. When people go to the doctor for a standard checkup or blood work, they often get a CBC. Suppose a person is healthy and their results are within normal ranges. In that case, they may not need another CBC unless their health condition changes, or their healthcare professional believes it is necessary. 

When a person exhibits a variety of signs and symptoms that could be connected to blood cell abnormalities, a CBC may be done. A health practitioner may request a CBC to help diagnose and determine the severity of lethargy or weakness, as well as infection, inflammation, bruises, or bleeding. 

When a person is diagnosed with a disease that affects blood cells, a CBC is frequently done regularly to keep track of their progress. Similarly, if someone is being treated for a blood condition, a CBC may be performed on a regular basis to see if the treatment is working. 

Chemotherapy, for example, can influence the generation of cells in the bone marrow. Some drugs can lower WBC counts in the long run. To monitor various medication regimens, a CBC may be required on a regular basis. 

What does a Complete Blood Count test check for? 

The complete blood count (CBC) is a blood test that determines the number of cells in circulation. White blood cells (WBCs), red blood cells (RBCs), and platelets (PLTs) are three types of cells suspended in a fluid called plasma. They are largely created and matured in the bone marrow and are released into the bloodstream when needed under normal circumstances. 

A CBC is mainly performed with an automated machine that measures a variety of factors, including the number of cells present in a person's blood sample. The findings of a CBC can reveal not only the quantity of different cell types but also the physical properties of some of the cells. 

Significant differences in one or more blood cell populations may suggest the presence of one or more diseases. Other tests are frequently performed to assist in determining the reason for aberrant results. This frequently necessitates visual confirmation via a microscope examination of a blood smear. A skilled laboratory technician can assess the appearance and physical features of blood cells, such as size, shape, and color, and note any anomalies. Any extra information is taken note of and communicated to the healthcare provider. This information provides the health care provider with further information about the cause of abnormal CBC results. 

The CBC focuses on three different types of cells: 

WBCs (White Blood Cells) 

The body uses five different types of WBCs, also known as leukocytes, to keep itself healthy and battle infections and other types of harm. The five different leukocytes are eosinophiles, lymphocytes, neutrophiles, basophils, and monocytes. They are found in relatively steady numbers in the blood. Depending on what is going on in the body, these values may momentarily rise or fall. An infection, for example, can cause the body to manufacture more neutrophils in order to combat bacterial infection. The amount of eosinophils in the body may increase as a result of allergies. A viral infection may cause an increase in lymphocyte production. Abnormal (immature or mature) white cells multiply fast in certain illness situations, such as leukemia, raising the WBC count. 

RBCs (Red Blood Cells) 

The bone marrow produces red blood cells, also known as erythrocytes, which are transferred into the bloodstream after maturing. Hemoglobin, a protein that distributes oxygen throughout the body, is found in these cells. Because RBCs have a 120-day lifespan, the bone marrow must constantly manufacture new RBCs to replace those that have aged and disintegrated or have been lost due to hemorrhage. A variety of diseases, including those that cause severe bleeding, can alter the creation of new RBCs and their longevity. 

The CBC measures the number of RBCs and hemoglobin in the blood, as well as the proportion of RBCs in the blood (hematocrit), and if the RBC population appears to be normal. RBCs are generally homogeneous in size and shape, with only minor differences; however, considerable variances can arise in illnesses including vitamin B12 and folate inadequacy, iron deficiency, and a range of other ailments. Anemia occurs when the concentration of red blood cells and/or the amount of hemoglobin in the blood falls below normal, resulting in symptoms such as weariness and weakness. In a far smaller percentage of cases, there may be an excess of RBCs in the blood (erythrocytosis or polycythemia). This might obstruct the flow of blood through the tiny veins and arteries in extreme circumstances. 

Platelets 

Platelets, also known as thrombocytes, are small cell fragments that aid in the regular clotting of blood. A person with insufficient platelets is more likely to experience excessive bleeding and bruises. Excess platelets can induce excessive clotting or excessive bleeding if the platelets are not operating properly. The platelet count and size are determined by the CBC. 

Lab tests often ordered with a Complete Blood Count test: 

  • Reticulocytes
  • Iron and Total Iron Binding Capacity
  • Basic Metabolic Panel
  • Comprehensive Metabolic Panel
  • Lipid Panel
  • Vitamin B12 and Folate
  • Prothrombin with INR and Partial Thromboplastin Times
  • Sed Rate (ESR)
  • C-Reactive Protein
  • Epstein-Barr Virus
  • Von Willebrand Factor Antigen

Conditions where a Complete Blood Count test is recommended: 

  • Anemia
  • Aplastic Anemia
  • Iron Deficiency Anemia
  • Vitamin B12 and Folate Deficiency
  • Sickle Cell Anemia
  • Heart Disease
  • Thalassemia
  • Leukemia
  • Autoimmune Disorders
  • Cancer
  • Bleeding Disorders
  • Inflammation
  • Epstein-Barr Virus
  • Mononucleosis

Commonly Asked Questions: 

How does my health care provider use a Complete Blood Count test? 

The complete blood count (CBC) is a common, comprehensive screening test used to measure a person's overall health status.  

What do my Complete Blood Count results mean? 

A low Red Blood Cell Count, also known as anemia, could be due many different causes such as chronic bleeding, a bone marrow disorder, and nutritional deficiency just to name a few. A high Red Blood Cell Count, also known as polycythemia, could be due to several conditions including lung disease, dehydration, and smoking. Both Hemoglobin and Hematocrit tend to reflect Red Blood Cell Count results, so if your Red Blood Cell Count is low, your Hematocrit and Hemoglobin will likely also be low. Results should be discussed with your health care provider who can provide interpretation of your results and determine the appropriate next steps or lab tests to further investigate your health. 

What do my Differential results mean? 

A low White Blood Cell count or low WBC count, also known as leukopenia, could be due to a number of different disorders including autoimmune issues, severe infection, and lymphoma. A high White Blood Cell count, or high WBC count, also known as leukocytosis, can also be due to many different disorders including infection, leukemia, and inflammation. Abnormal levels in your White Blood Cell Count will be reflected in one or more of your different white blood cells. Knowing which white blood cell types are affected will help your healthcare provider narrow down the issue. Results should be discussed with your health care provider who can provide interpretation of your results and determine the appropriate next steps or lab tests to further investigate your health. 

What do my Platelet results mean? 

A low Platelet Count, also known as thrombocytopenia, could be due to a number of different disorders including autoimmune issues, viral infection, and leukemia. A high Platelet Count, also known as Thrombocytosis, can also be due to many different disorders including cancer, iron deficiency, and rheumatoid arthritis. Results should be discussed with your health care provider who can provide interpretation of your results and determine the appropriate next steps or lab tests to further investigate your health. 

NOTE: Only measurable biomarkers will be reported. Certain biomarkers do not appear in healthy individuals. 

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.

Reflex Parameters for Manual Slide Review
  Less than  Greater Than 
WBC  1.5 x 10^3  30.0 x 10^3 
Hemoglobin  7.0 g/dL  19.0 g/dL 
Hematocrit  None  75%
Platelet  100 x 10^3  800 x 10^3 
MCV  70 fL  115 fL 
MCH  22 pg  37 pg 
MCHC  29 g/dL  36.5 g/dL 
RBC  None  8.00 x 10^6 
RDW  None  21.5
Relative Neutrophil %  1% or ABNC <500  None 
Relative Lymphocyte %  1% 70%
Relative Monocyte %  None  25%
Eosinophil  None  35%
Basophil  None  3.50%
     
Platelet  <75 with no flags,
>100 and <130 with platelet clump flag present,
>1000 
Instrument Flags Variant lymphs, blasts,
immature neutrophils,  nRBC’s, abnormal platelets,
giant platelets, potential interference
     
The automated differential averages 6000+ cells. If none of the above parameters are met, the results are released without manual review.
CBC Reflex Pathway

Step 1 - The slide review is performed by qualified Laboratory staff and includes:

  • Confirmation of differential percentages
  • WBC and platelet estimates, when needed
  • Full review of RBC morphology
  • Comments for toxic changes, RBC inclusions, abnormal lymphs, and other
  • significant findings
  • If the differential percentages agree with the automated counts and no abnormal cells are seen, the automated differential is reported with appropriate comments

Step 2 - The slide review is performed by qualified Laboratory staff and includes: If any of the following are seen on the slide review, Laboratory staff will perform a manual differential:

  • Immature, abnormal, or toxic cells
  • nRBC’s
  • Disagreement with automated differential
  • Atypical/abnormal RBC morphology
  • Any RBC inclusions

Step 3 If any of the following are seen on the manual differential, a Pathologist will review the slide:

  • WBC<1,500 with abnormal cells noted
  • Blasts/immature cells, hairy cell lymphs, or megakaryocytes
  • New abnormal lymphocytes or monocytes
  • Variant or atypical lymphs >15%
  • Blood parasites
  • RBC morphology with 3+ spherocytes, RBC inclusions, suspect Hgb-C,
  • crystals, Pappenheimer bodies or bizarre morphology
  • nRBC’s

Description: A Comprehensive Metabolic Panel or CMP is a blood test that is a combination of a Basic Metabolic Panel, a Liver Panel, and electrolyte panel, and is used to screen for, diagnose, and monitor a variety of conditions and diseases such as liver disease, diabetes, and kidney disease. 

Also Known As: CMP, Chem, Chem-14, Chem-12, Chem-21, Chemistry Panel, Chem Panel, Chem Screen, Chemistry Screen, SMA 12, SMA 20, SMA 21, SMAC, Chem test

Collection Method: 

Blood Draw 

Specimen Type: 

Serum 

Test Preparation: 

9-12 hours fasting is preferred. 

When is a Comprehensive Metabolic Panel test ordered:  

A CMP is frequently requested as part of a lab test for a medical evaluation or yearly physical. A CMP test consists of many different tests that give healthcare providers a range of information about your health, including liver and kidney function, electrolyte balance, and blood sugar levels. To confirm or rule out a suspected diagnosis, abnormal test results are frequently followed up with other tests that provide a more in depth or targeted analysis of key areas that need investigating. 

What does a Comprehensive Metabolic Panel blood test check for? 

The complete metabolic panel (CMP) is a set of 20 tests that provides critical information to a healthcare professional about a person's current metabolic status, check for liver or kidney disease, electrolyte and acid/base balance, and blood glucose and blood protein levels. Abnormal results, particularly when they are combined, can suggest a problem that needs to be addressed. 

The following tests are included in the CMP: 

  • Albumin: this is a measure of Albumin levels in your blood. Albumin is a protein made by the liver that is responsible for many vital roles including transporting nutrients throughout the body and preventing fluid from leaking out of blood vessels. 

  • Albumin/Globulin Ratio: this is a ratio between your total Albumin and Globulin  

  • Alkaline Phosphatase: this is a measure of Alkaline phosphatase or ALP in your blood. Alkaline phosphatase is a protein found in all body tissues, however the ALP found in blood comes from the liver and bones. Elevated levels are often associated with liver damage, gallbladder disease, or bone disorder. 

  • Alt: this is a measure of Alanine transaminase or ALT in your blood. Alanine Aminotransferase is an enzyme found in the highest amounts in the liver with small amounts in the heart and muscles. Elevated levels are often associated with liver damage. 

  • AST: this is a measure of Aspartate Aminotransferase or AST. Aspartate Aminotransferase is an enzyme found mostly in the heart and liver, with smaller amounts in the kidney and muscles. Elevated levels are often associated with liver damage. 

  • Bilirubin, Total: this is a measure of bilirubin in your blood. Bilirubin is an orange-yellowish waste product produced from the breakdown of heme which is a component of hemoglobin found in red blood cells. The liver is responsible for removal of bilirubin from the body. 

  • Bun/Creatinine Ratio: this is a ratio between your Urea Nitrogen (BUN) result and Creatinine result.  

  • Calcium: this is a measurement of calcium in your blood. Calcium is the most abundant and one of the most important minerals in the body as it essential for proper nerve, muscle, and heart function. 

  • Calcium: is used for blood clot formation and the formation and maintenance of bones and teeth. 

  • Carbon Dioxide: this is a measure of carbon dioxide in your blood. Carbon dioxide is a negatively charged electrolyte that works with other electrolytes such as chloride, potassium, and sodium to regulate the body’s acid-base balance and fluid levels.  

  • Chloride: this is a measure of Chloride in your blood. Chloride is a negatively charged electrolyte that works with other electrolytes such as potassium and sodium to regulate the body’s acid-base balance and fluid levels. 

  • Creatinine: this is a measure of Creatinine levels in your blood. Creatinine is created from the breakdown of creatine in your muscles and is removed from your body by the kidneys. Elevated creatinine levels are often associated with kidney damage. 

  • Egfr African American: this is a measure of how well your kidneys are functioning. Glomeruli are tiny filters in your kidneys that filter out waste products from your blood for removal while retaining important substances such as nutrients and blood cells. 

  • Egfr Non-Afr. American: this is a measure of how well your kidneys are functioning. Glomeruli are tiny filters in your kidneys that filter out waste products from your blood for removal while retaining important substances such as nutrients and blood cells. 

  • Globulin: this is a measure of all blood proteins in your blood that are not albumin. 

  • Glucose: this is a measure of glucose in your blood. Glucose is created from the breakdown of carbohydrates during digestion and is the body’s primary source of energy. 

  • Potassium: this is a measure of Potassium in your blood. Potassium is an electrolyte that plays a vital role in cell metabolism, nerve and muscle function, and transport of nutrients into cells and removal of wastes products out of cells. 

  • Protein, Total: this is a measure of total protein levels in your blood. 
    Sodium: this is a measure of Sodium in your blood. Sodium is an electrolyte that plays a vital role in nerve and muscle function. 

  • Urea Nitrogen (Bun): this is a measure of Urea Nitrogen in your blood, also known as Blood UreaNitrogen (BUN). Urea is a waste product created in the liver when proteins are broken down into amino acids. Elevated levels are often associated with kidney damage. 

Lab tests often ordered with a Comprehensive Metabolic Panel test: 

  • Complete Blood Count with Differential and Platelets
  • Iron and Total Iron Binding Capacity
  • Lipid Panel
  • Vitamin B12 and Folate
  • Prothrombin with INR and Partial Thromboplastin Times
  • Sed Rate (ESR)
  • C-Reactive Protein

Conditions where a Comprehensive Metabolic Panel test is recommended: 

  • Diabetes
  • Kidney Disease
  • Liver Disease
  • Hypertension

Commonly Asked Questions: 

How does my health care provider use a Comprehensive Metabolic Panel test? 

The comprehensive metabolic panel (CMP) is a broad screening tool for assessing organ function and detecting diseases like diabetes, liver disease, and kidney disease. The CMP test may also be requested to monitor known disorders such as hypertension and to check for any renal or liver-related side effects in persons taking specific drugs. If a health practitioner wants to follow two or more separate CMP components, the full CMP might be ordered because it contains more information. 

What do my Comprehensive Metabolic Panel test results mean? 

The results of the tests included in the CMP are usually analyzed together to look for patterns. A single abnormal test result may indicate something different than a series of abnormal test findings. A high result on one of the liver enzyme tests, for example, is not the same as a high result on several liver enzyme tests. 

Several sets of CMPs, frequently performed on various days, may be examined to gain insights into the underlying disease and response to treatment, especially in hospitalized patients. 

Out-of-range findings for any of the CMP tests can be caused by a variety of illnesses, including kidney failure, breathing issues, and diabetes-related complications, to name a few. If any of the results are abnormal, one or more follow-up tests are usually ordered to help determine the reason and/or establish a diagnosis. 

Is there anything else I should know? 

A wide range of prescription and over-the-counter medications can have an impact on the results of the CMP's components. Any medications you're taking should be disclosed to your healthcare professional. Similarly, it is critical to provide a thorough history because many other circumstances can influence how your results are interpreted. 

What's the difference between the CMP and the BMP tests, and why would my doctor choose one over the other? 

The CMP consists of 14 tests, while the basic metabolic panel (BMP) is a subset of those with eight tests. The liver (ALP, ALT, AST, and bilirubin) and protein (albumin and total protein) tests are not included. If a healthcare provider wants a more thorough picture of a person's organ function or to check for specific illnesses like diabetes or liver or kidney disease, he or she may prescribe a CMP rather than a BMP. 

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.

Please note the following regarding BUN/Creatinine ratio: 

The lab does not report the calculation for the BUN/Creatinine Ratio unless one or both biomarkers’ results fall out of the published range. 

If you still wish to see the value, it's easy to calculate. Simply take your Urea Nitrogen (BUN) result and divide it by your Creatinine result.  

As an example, if your Urea Nitrogen result is 11 and your Creatinine result is 0.86, then you would divide 11 by 0.86 and get a BUN/Creatinine Ratio result of 12.79. 


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Description: A Ferritin test is a blood test that measures Ferritin levels in your blood’s serum to evaluate the level of iron stored in your body.

Also Known As: Ferritin Serum Test, Ferritin Test, Ferritin Blood Test

Collection Method: Blood Draw

Specimen Type: Serum

Test Preparation: No preparation required

When is a Ferritin test ordered?

When a CBC test’s implies iron deficiency anemia due to small red blood cells or low hematocrit and hemoglobin levels, the ferritin test, and other iron tests, may be requested, even if other clinical symptoms have not yet arisen.

There are frequently no physical symptoms in the early stages of iron insufficiency. Symptoms rarely develop before hemoglobin falls below dangerous levels. However, when the iron deficit continues, symptoms emerge, prompting a doctor to order ferritin and other iron-related testing. The following are the most prevalent symptoms of iron deficiency anemia:

  • Chronic tiredness/fatigue
  • Weakness
  • Dizziness
  • Headaches
  • Skin that is pale

Shortness of breath, ringing in the ears, sleepiness, and irritability may occur as iron levels are reduced. Chest pain, headaches, limb pains, shock, and even heart failure may occur as the anemia worsens. Learning impairments can occur in children. There are some symptoms that are specific to iron deficiency, in addition to the usual signs of anemia. Pica, a burning feeling in the tongue or a smooth tongue, ulcers at the corners of the mouth, and spoon-shaped finger- and toe-nails are only a few of the symptoms.

When iron overload is suspected, a ferritin level may be requested. Iron overload symptoms differ from person to person and tend to worsen over time. They are caused by an excess of iron in the blood and tissues. Among the signs and symptoms are:

  • Joint discomfort
  • Weakness and exhaustion
  • Loss of weight
  • Energy deficiency
  • Pain in the abdomen
  • Suffering from a lack of sexual desire
  • Hair loss on the body
  • Congestive heart failure is an example of a cardiac issue

Other iron tests including a genetic test for hereditary hemochromatosis may be conducted to confirm the existence of iron excess.

What does a Ferritin blood test check for?

Ferritin is an iron-containing protein that stores iron in cells in its most basic form. The amount of total iron stored in the body is reflected in the little amount of ferritin released into the blood. This test determines how much ferritin is present in the blood.

About 70% of the iron consumed by the body is integrated into the hemoglobin of red blood cells in healthy humans. The remaining 30% is stored primarily as ferritin or hemosiderin, which is a combination of iron, proteins, and other elements. Hemosiderin and ferritin are typically found in the liver, although they can also be found in the bone marrow, spleen, and skeletal muscles.

Iron stores are depleted and ferritin levels fall when available iron is insufficient to meet the body's needs. This can happen owing to a lack of iron, poor absorption, or an increased need for iron, such as during pregnancy or if you have a condition that causes persistent blood loss. Before any indicators of iron shortage appear, significant loss of iron reserves may occur.

When the body absorbs more iron than it needs, iron storage and ferritin levels rise. Chronic iron absorption causes a gradual buildup of iron compounds in organs, which can eventually lead to organ malfunction and failure. Even on a typical diet, this happens in hemochromatosis, a hereditary disorder in which the body absorbs too much iron.

Lab tests often ordered with a Ferritin test:

  • Complete Blood Count
  • Iron Total
  • Iron Total and Total Iron binding capacity
  • Transferrin
  • Comprehensive Metabolic Panel
  • Lipid Panel
  • Zinc Protoporphyrin

Conditions where a Ferritin test is recommended:

  • Anemia
  • Hemochromatosis
  • Lead poisoning
  • Pregnancy
  • Restless Leg Syndrome

How does my health care provider use a Ferritin test?

The ferritin test is used to determine the amount of iron a person has in their body. To determine the existence and severity of iron shortage or iron overload, the test is sometimes ordered in conjunction with an iron test and a TIBC test.

One source of iron overload can be the use of iron supplements.

What does my ferritin lab test result mean?

Ferritin levels are frequently measured alongside other iron tests.

Ferritin levels are low in iron deficient people and high in people who have hemochromatosis or have had several blood transfusions.

Ferritin is an acute phase reactant that can be elevated in persons who have inflammation, liver illness, chronic infection, autoimmune disorders, or cancer. Ferritin isn't commonly utilized to detect or monitor these problems.

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.


Functional Thyroid Panel contains the following tests.

  • CBC (includes Differential and Platelets)
  • Comprehensive Metabolic Panel (CMP)
  • Ferritin
  • Hemoglobin A1c (HgbA1C)
  • Insulin
  • Lipid Panel With Ratios
  • QuestAssureD™ 25-Hydroxyvitamin D (D2, D3), LC/MS/MS
  • T3 Reverse (RT3), LC/MS/MS
  • T3, Free
  • T4 (Thyroxine), Total
  • T4, Free
  • Thyroid Peroxidase and Thyroglobulin Antibodies
  • TSH

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Description: A Glucose test is a blood test used to screen for, diagnose, and monitor conditions that affect glucose levels such as prediabetes, diabetes, hyperglycemia, and hypoglycemia.

Also Known As: Fasting Blood Glucose Test, FBG Test, Fasting Blood Sugar Test, FBS Test, Fasting Glucose Test, FG Test

Collection Method: Blood Draw

Specimen Type: Serum

Test Preparation: Fasting required

When is a Glucose test ordered?

Diabetes screening is recommended by several health groups, including the American Diabetes Association and the United States Preventive Services Task Force, when a person is 45 years old or has risk factors.

The ADA recommends retesting within three years if the screening test result is within normal limits, but the USPSTF recommends testing once a year. Annual testing may be used to monitor people with prediabetes.

When someone exhibits signs and symptoms of high blood glucose, a blood glucose test may be conducted.

Diabetics are frequently asked to self-check their glucose levels multiple times a day in order to monitor glucose levels and choose treatment alternatives as suggested by their doctor. Blood glucose levels may be ordered on a regular basis, along with other tests such as A1c, to track glucose control over time.

Unless they show early symptoms or have had gestational diabetes in a prior pregnancy, pregnant women are routinely screened for gestational diabetes between the 24th and 28th week of pregnancy. If a woman is at risk of type 2 diabetes, she may be tested early in her pregnancy, according to the American Diabetes Association. When a woman has type 1, type 2, or gestational diabetes, her health care provider will normally order glucose levels to monitor her condition throughout the duration of her pregnancy and after delivery.

What does a Glucose blood test check for?

A fasting glucose test measures glucose. Glucose is the major energy source for the body's cells and the brain and nervous system's only source of energy. A consistent supply must be provided, and a somewhat constant level of glucose in the blood must be maintained. The glucose level in the blood can be measured using a variety of methods. 

Fruits, vegetables, breads, and other carbohydrate-rich foods are broken down into glucose during digestion, which is absorbed by the small intestine and circulated throughout the body. Insulin, a hormone generated by the pancreas, is required for the use of glucose for energy production. Insulin promotes glucose transport into cells and instructs the liver to store surplus energy as glycogen for short-term storage or triglycerides in adipose cells.

Normally, blood glucose rises slightly after you eat or drink, and the pancreas responds by releasing insulin into the blood, the amount of which is proportional to the size and substance of the meal. The level of glucose in the blood declines as glucose enters the cells and is digested, and the pancreas responds by delaying, then ceasing the secretion of insulin.

When blood glucose levels fall too low, such as between meals or after a strong activity, glucagon is released, which causes the liver to convert some glycogen back into glucose, so boosting blood glucose levels. The level of glucose in the blood remains pretty steady if the glucose/insulin feedback loop is working appropriately. When the balance is upset and the blood glucose level rises, the body strives to restore it by boosting insulin production and removing excess glucose through the urine.

Several diseases can cause the equilibrium between glucose and pancreatic hormones to be disrupted, resulting in high or low blood glucose. Diabetes is the most common cause. Diabetes is a collection of illnesses characterized by inadequate insulin production and/or insulin resistance. Untreated diabetes impairs a person's ability to digest and utilize glucose normally. Type 1 diabetes is diagnosed when the body is unable to produce any or enough insulin. People with prediabetes or type 2 diabetes are insulin resistant and may or may not be able to produce enough of the hormone.

Organ failure, brain damage, coma, and, in extreme situations, death can result from severe, sudden fluctuations in blood glucose, either high or low. Chronically high blood glucose levels can harm body organs like the kidneys, eyes, heart, blood vessels, and nerves over time. Hypoglycemia can harm the brain and nerves over time.

Gestational diabetes, or hyperglycemia that exclusively arises during pregnancy, can affect some women. If left untreated, this can result in large babies with low glucose levels being born to these mothers. Women with gestational diabetes may or may not acquire diabetes later in life.

Lab tests often ordered with a Glucose test:

  • Complete Blood Count
  • Iron Total and Total Iron binding capacity
  • Hemoglobin A1c
  • Lipid Panel
  • Urinalysis Complete
  • TSH
  • CMP
  • Insulin
  • Microalbumin
  • Fructosamine
  • C-Peptide

Conditions where a Glucose test is recommended:

  • Diabetes
  • Kidney Disease
  • Insulin Resistance
  • Pancreatic Diseases
  • Hyperglycemia
  • Hypoglycemia

Commonly Asked Questions:

How does my health care provider use a Glucose test?

The blood glucose test can be used for a variety of purposes, including:

  • Detect hyperglycemia and hypoglycemia
  • Screen for diabetes in those who are at risk before symptoms appear; there may be no early indications or symptoms of diabetes in some circumstances. As a result, screening can aid in detecting it and allowing treatment to begin before the illness worsens or complications emerge.
  • Aid in the detection of diabetes, prediabetes, and gestational diabetes.
  • Monitor your blood sugar levels and manage your diabetes

Glucose levels should be monitored in those who have been diagnosed with diabetes.

Between the 24th and 28th week of pregnancy, glucose blood tests are performed to assess pregnant women for gestational diabetes. Pregnant women who have never been diagnosed with diabetes should be screened and diagnosed using either a one-step or two-step strategy, according to the American Diabetes Association and the US Preventive Services Task Force.

Other tests, including diabetic autoantibodies, insulin, and C-peptide, may be used in conjunction with glucose to assist in detecting the reason of elevated glucose levels, differentiate between type 1 and type 2 diabetes, and assess insulin production.

What does my glucose test result mean?

High blood glucose levels are most commonly associated with diabetes, but they can also be caused by a variety of other diseases and ailments.

Hypoglycemia is defined by a drop in blood glucose to a level that triggers nervous system symptoms before affecting the brain. The Whipple triad is a set of three criteria for diagnosing hypoglycemia.

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.


Description: Hemoglobin A1c is the protein Hemoglobin found in red blood cells, but with glucose attached to it. Hemoglobin A1c is used to check for and monitor diabetes as it shows average blood glucose levels over the past 2 to 3 months.

Also Known As: A1c Test, HbA1c Test, Glycohemoglobin Test, Glycated Hemoglobin Test, Glycosylated Hemoglobin Test, HbA1c Test

Collection Method: Blood Draw

Specimen Type: Whole Blood

Test Preparation: No preparation required

When is a Hemoglobin A1c test ordered?

A1c may be requested as part of a routine physical examination or when a practitioner suspects a patient of having diabetes due to characteristic signs or symptoms of high blood sugar, such as:

  • Increased thirst and fluid intake
  • Increased urination
  • Increase in hunger
  • Fatigue
  • Vision is hazy
  • Infections that take a long time to heal

Adults who are overweight and have the following additional risk factors may consider doing the A1c test:

  • Physically inactive
  • Diabetes in a first-degree relative
  • Race/ethnicity that is at high risk such as African Americans, Latinos, Native Americans, Asian Americans, and Pacific Islanders
  • Blood pressure that is high
  • A lipid profile that is abnormal.
  • Polycystic ovarian syndrome 
  • Cardiovascular disease 
  • Insulin resistance and other conditions links to insulin resistance

People who have not been diagnosed with diabetes but have been assessed to be at an increased risk of developing diabetes should have their A1c levels tested at least once a year.

Monitoring

The A1c test may be performed 2 to 4 times a year, depending on the type of diabetes a person has, how well their diabetes is controlled, and the healthcare provider's recommendations. If diabetics are fulfilling treatment goals and have stable glycemic control, the American Diabetes Association advises A1c testing at least twice a year. A1c may be ordered quarterly when someone is first diagnosed with diabetes or if control isn't good.

What does a Hemoglobin A1c blood test check for?

Hemoglobin A1c, often known as A1c or glycated hemoglobin, is hemoglobin that has been attached to glucose. By assessing the proportion of glycated hemoglobin, the A1c test determines the average quantity of glucose in the blood during the previous 2 to 3 months.

Hemoglobin is a protein present inside red blood cells that transports oxygen.

Glycated hemoglobin is generated in proportion to the amount of glucose in the blood. Once glucose attaches to hemoglobin, it stays there for the duration of the red blood cell's life, which is usually about 120 days. The most common kind of glycated hemoglobin is known as A1c. A1c is created on a daily basis and is gradually removed from the bloodstream as older RBCs die and younger RBCs replace them.

This test can be used to detect and diagnose diabetes, as well as the risk of developing it. According to the American Diabetes Association's standards of medical care in diabetes, diabetes can be diagnosed using either A1c or glucose.

This test can also be used to track the progress of a diabetic patient's treatment. It aids in determining how well a person's glucose levels have been controlled over time by medication. An A1c of less than 7% suggests good glucose control and a lower risk of diabetic complications for the majority of diabetics for monitoring reasons.

Lab tests often ordered with a Hemoglobin A1c test:

  • Complete Blood Count
  • Glucose
  • Frucstosamine
  • Albumin
  • Comprehensive Metabolic Panel
  • Microalbumin w/creatinine
  • Lipid panel

Conditions where a Hemoglobin A1c test is recommended:

  • Type 1 Diabetes
  • Type 2 Diabetes

How does my health care provider use a Hemoglobin A1c test?

Adults can use the hemoglobin A1c test to screen for and diagnose diabetes and prediabetes.

A fasting glucose or oral glucose tolerance test should be done to screen or diagnose diabetes in these instances.

The A1c test is also used to track diabetics' glucose control over time. Diabetics strive to maintain blood glucose levels that are as close to normal as feasible. This helps to reduce the risks of consequences associated with chronically high blood sugar levels, such as progressive damage to body organs such as the kidneys, eyes, cardiovascular system, and nerves. The result of the A1c test depicts the average quantity of glucose in the blood over the previous 2-3 months. This can help diabetics and their healthcare professionals determine whether the steps they're taking to control their diabetes are working or if they need to be tweaked.

A1c is a blood test that is usually used to help newly diagnosed diabetics identify how high their uncontrolled blood glucose levels have been in the previous 2-3 months. The test may be ordered multiple times throughout the control period, and then at least twice a year after that to ensure that good control is maintained.

What does my Hemoglobin A1c test result mean?

HbA1c levels is currently reported as a percentage for monitoring glucose control, and it is suggested that most diabetics try to keep their hemoglobin A1c below 7%. The closer diabetics can keep their A1c to the therapeutic objective of less than 7% without experiencing abnormally low blood glucose, the better their diabetes is controlled. The risk of problems rises as the A1c rises.

However, a person with type 2 diabetes may have an A1c goal set by their healthcare professional. The length of time since diagnosis, the presence of other diseases as well as diabetes complications, the risk of hypoglycemia complications, life expectancy, and whether or not the person has a support system and healthcare resources readily available are all factors that may influence the goal.

For example, a person with heart disease who has had type 2 diabetes for many years without diabetic complications may have a higher A1c target set by their healthcare provider, whereas someone who is otherwise healthy and newly diagnosed may have a lower target set by their healthcare provider as long as low blood sugar is not a significant risk.

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.


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Description: The Hepatic Function Panel is a blood test that measures multiple markers to evaluate the health of your liver.

Also Known As: Liver Profile Test, Liver Function Test, LFT, Liver Enzyme Test, Liver Test, Liver Blood Test

Collection Method: Blood Draw

Specimen Type: Serum

Test Preparation: No preparation required

When is a Hepatic Function Panel test ordered?

When someone is at risk for liver dysfunction, a liver panel, or one or more of its components, may be requested. Here are a few examples:

  • People who are taking drugs that could harm their liver
  • Those who are alcoholics or who use a lot of alcohol
  • Those who have a history of hepatitis virus exposure, either known or suspected
  • Individuals with a history of liver illness in their families
  • Overweight people, especially those with diabetes and/or high blood pressure

When a person exhibits signs and symptoms of liver disease, a liver panel may be done; however, most people with liver disease do not have any of these symptoms until the disease has been present for years or is very severe. Here are a few examples:

  • Weakness and exhaustion
  • Appetite loss.
  • Vomiting and nausea
  • Swelling and/or pain in the abdomen
  • Jaundice
  • Urine that is dark in color and feces that is light in color
  • Pruritus
  • Diarrhea

To make a diagnosis, no single collection of liver tests is usually used. Several liver panels are frequently done over the course of a few days or weeks to aid in determining the source of the liver illness and assessing its severity.

When liver illness is discovered, the liver panel or one or more of its components can be used to monitor it on a regular basis over time. A liver panel may be conducted on a regular basis to assess the efficacy of treatment for the liver condition.

What does a Hepatic Function Panel blood test check for?

A liver panel is a collection of tests used to diagnose, evaluate, and track the progression of liver illness or damage. The liver is one of the largest organs in the body, and it is placed behind the lower ribs in the upper right section of the belly. Drugs and substances that are detrimental to the body are metabolized and detoxified by the liver. It makes blood clotting factors, proteins, and enzymes, as well as regulating hormone levels and storing vitamins and minerals. Bile, a fluid produced by the liver, is delivered to the small intestine via ducts to aid in fat digestion or to the gallbladder to be stored and concentrated for later use.

Inflammation, scarring, bile duct blockages, liver tumors, and liver dysfunction can all be caused by a range of disorders and infections that cause acute or chronic liver damage. Toxins, alcohol, narcotics, and some herbal medications can all be dangerous. Before signs like jaundice, dark urine, light-colored feces, itching, nausea, exhaustion, diarrhea, and unexplained weight loss or increase appear, there may be considerable liver damage. To reduce damage and preserve liver function, early identification is critical.

The liver panel assesses the enzymes, proteins, and chemicals generated, processed, or removed by the liver, as well as those that are altered by liver injury. Some are produced by damaged liver cells, while others indicate a reduction in the liver's ability to execute one or more activities. When these tests are performed combined, they provide a picture of a person's liver's health, an indication of the severity of any liver injury, changes in liver status over time, and a starting point for further diagnostic testing.

Lab tests often ordered with a Hepatic Function Panel test:

  • GGT
  • Prothrombin Time and International Normalized Ratio
  • LD
  • Hepatitis A Testing
  • Hepatitis B Testing
  • Hepatitis C Testing
  • Emergency and Overdose Drug Testing
  • Ethanol
  • ANA
  • Smooth Muscle Antibody
  • Anti-LKM-1
  • Drugs of Abuse Testing
  • Copper
  • Ceruloplasmin
  • DCP
  • AFP Tumor Markers
  • Alpha-1
  • Antitrypsin
  • Acetaminophen
  • Ammonia

Conditions where a Hepatic Function Panel test is recommended:

  • Liver Disease
  • Jaundice
  • Hepatitis
  • Hemochromatosis
  • Wilson Disease
  • Cirrhosis

Commonly Asked Questions:

How does my health care provider use a Hepatic Function Panel test?

A liver panel can be performed to check for damage to the liver, especially if someone has an illness or is taking a medication that could harm the liver. For regular screening, a comprehensive metabolic panel, which is commonly conducted as part of a general health checkup, may be ordered instead of a liver panel. The majority of the liver panel is included in this group of tests, as well as other tests that evaluate other organs and systems in the body.

If a person has signs and symptoms that indicate suspected liver malfunction, a liver panel or one or more of its component tests may be done to assist identify liver disease. If a person has a known illness or liver disease, testing may be done at regular intervals to assess the liver's health and the efficiency of any therapies. To evaluate and monitor a jaundiced newborn, a variety of bilirubin tests may be ordered.

Abnormal tests on a liver panel may necessitate a repeat study of one or more tests, or the entire panel, to evaluate if the elevations or declines continue, and/or additional testing to discover the etiology of the liver dysfunction.

Typically, a panel consists of numerous tests performed simultaneously on a blood sample.

What do my Liver Panel Test results mean?

The findings of a liver panel test are not diagnostic of a specific condition; rather, they show that the liver may be malfunctioning. Abnormal liver test results in a person who has no symptoms or recognized risk factors may signal a transitory liver injury or reflect something going on elsewhere in the body, such as the skeletal muscles, pancreas, or heart. It could potentially signal the presence of early liver disease, necessitating more testing and/or periodic monitoring.

The results of liver panels are generally compared. Several sets of results from tests conducted over several days or weeks are sometimes analyzed together to see if a pattern emerges. Each person's test findings will be unique, and they will most likely alter over time. A healthcare professional examines the combined findings of liver tests to learn more about the underlying disease. Further testing is frequently required to discover the cause of the liver damage and/or illness.

Abnormal test results may signal a need to review a person's dosage or medication choice if they are taking medicines that may impact their liver. When a person with liver disease is being monitored, the healthcare provider will look at the findings of the liver panel together to see if liver function or damage is getting worse or better. Increased abnormalities in bilirubin, albumin, and/or PT, for example, may suggest a decline in liver function, whereas steady or improved findings may indicate liver function preservation or improvement.

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.


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Brief Description: An Insulin test is a blood test that measures the insulin levels in the blood's serum. It is a measurement that is heavily used in patients with diabetes.

Also Known As: Fasting Insulin Test, Insulin Assay Test, Insulin Serum Test

Collection Method: Blood Draw

Specimen Type: Serum

Test Preparation: 9 Hours Fasting Required

When is an Insulin test ordered?

Insulin levels are most commonly ordered after a low glucose result or when someone has acute or chronic symptoms of hypoglycemia.  Hypoglycemia can cause the following symptoms:

  • Sweating
  • Palpitations
  • Hunger
  • Brain fox
  • Hazy vision
  • Dizziness
  • Fainting

Seizures and loss of consciousness are common in severe instances.

While low blood glucose can cause these symptoms, they can also be caused by other illnesses.

When a person has or is suspected of having insulin resistance, an insulin test may be performed. People with type 2 diabetes, polycystic ovary syndrome, prediabetes or cardiac disease, or metabolic syndrome may fall into this category.

After an insulinoma has been effectively removed, a health practitioner may arrange insulin and C-peptide testing to verify the effectiveness of treatment and subsequently order the tests on a regular basis to monitor for recurrence.

Periodic testing can also be performed to track the success of an islet cell transplant by determining the graft's insulin-producing capacity.

What does an Insulin blood test check for?

Insulin is a hormone produced in the pancreas' beta cells and stored there. It is necessary for the transfer and storage of glucose, the body's primary energy source. Insulin aids in the delivery of glucose from the bloodstream to cells, as well as the regulation of blood glucose levels and lipid metabolism. This test determines how much insulin is present in the blood.

The levels of insulin and glucose in the blood must be balanced. Carbohydrates are frequently broken down into glucose and other simple sugars after a meal. The blood glucose level rises, prompting the pancreas to produce insulin into the bloodstream. The amount of glucose in the blood reduces as it enters cells, and the amount of insulin released by the pancreas decreases.

If an individual is unable to produce enough insulin, or if the body's cells become resistant to its effects, glucose is unable to reach the majority of the body's cells, causing the cells to starve as blood glucose climbs to harmful levels. This can disrupt normal metabolic processes, leading to a variety of illnesses and difficulties, such as kidney disease, cardiovascular disease, and eyesight and neurological issues.

Diabetes is a life-threatening illness characterized by excessive glucose levels and diminished insulin action. People with type 1 diabetes produce relatively little insulin, necessitating the use of insulin supplements. Insulin resistance is a common cause of type 2 diabetes, which worsens over time.

Insulin resistance occurs when the body is unable to respond to insulin's effects. The body makes up for this by manufacturing more of the hormone. Hyperinsulinemia and overstimulation of some insulin-sensitive tissues happen as a result of this. This process generates an imbalance in the connection between glucose and insulin over time, which, if left untreated, can lead to health problems affecting numerous regions of the body.

Insulin resistance can be present in people with polycystic ovary syndrome, prediabetes or cardiac disease, metabolic syndrome, and diseases of the pituitary or adrenal glands, in addition to type 2 diabetes.

Hyperinsulinemia is most commonly seen in persons with tumors of the pancreatic islet cells or an excess of injected insulin, aside from insulin resistance. Low blood sugar is caused by hyperinsulinemia, which can cause sweating, hunger, palpitations, confusion, dizziness, blurred vision, seizures, and fainting. Because the brain relies on blood glucose for energy, severe glucose deprivation caused by hyperinsulinemia can swiftly result in insulin shock and death.

Lab tests often ordered with an Insulin test:

  • Glucose
  • Hemoglobin A1c
  • C-Peptide
  • Comprehensive Metabolic Panel

Conditions where an Insulin test is recommended:

  • Diabetes
  • Insulin Resistance
  • PCOS
  • Metabolic Syndrome

Commonly Asked Questions:

How does my health care provider use an insulin test?

Insulin testing can be used for a variety of purposes. Insulin is a hormone produced in the pancreas' beta cells and stored there. Insulin is a hormone that aids in the movement of glucose, the body's primary source of energy, from the bloodstream to the cells. Cells starve if a person produces too little insulin or is resistant to its effects. When someone produces too much insulin, such as when they have an insulin-producing tumor, symptoms of low blood glucose appear.

Insulin testing may be used to assist with the following:

  • Diagnose an insulinoma, confirm that the tumor was successfully removed, and/or keep an eye out for recurrence.
  • Determine the source of hypoglycemia in a person who has signs and symptoms.
  • Recognize insulin resistance.
  • In this instance, a C-peptide test may be used to monitor the quantity of insulin produced by the beta cells in the pancreas. As part of the conversion of proinsulin to insulin in the pancreas, the body produces both insulin and C-peptide at the same time. When a doctor wishes to know how much insulin is created by the body and how much comes from outside sources like insulin injections, both tests may be ordered. The C-peptide test indicates insulin produced by the pancreas, but the insulin test analyzes insulin from both sources.
  • Determine when a type 2 diabetic may need to supplement oral medications with insulin.

Insulin tests can be ordered in conjunction with glucose and C-peptide tests. In addition to the glucose tolerance test, insulin levels are sometimes employed. To assess insulin resistance, blood glucose and insulin levels are tested at pre-determined time intervals in this circumstance.

What do my Insulin test result mean?

Insulin levels must be reviewed in the context of other diagnostic tests and symptoms.

Insulin levels can be elevated with:

  • Acromegaly
  • Cushing's syndrome
  • Use of medications such as corticosteroids, levodopa, and oral contraceptives
  • Intolerance to fructose or galactose
  • Insulinomas
  • Obesity
  • Insulin resistance, as seen in type 2 diabetes and metabolic syndrome

Insulin levels can be low with:

  • Diabetes 
  • Hypopituitarism
  • Chronic pancreatitis 
  • Pancreatic cancer

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.


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Iodine is an essential element that is required for thyroid hormone production. The measurement of iodine serves as an index of adequate dietary intake.

Description: Iron and Total Iron Binding Capacity is a blood panel used to determine iron levels in your blood, your body’s ability to transport iron, and help diagnose iron-deficiency and iron overload.

Also Known As: Serum Iron Test, Serum Fe Test, Iron Binding Capacity Test, IBC Test, Serum Iron-Binding Capacity Siderophilin Test, TIBC Test, UIBC Test, Iron Lab Test, TIBC Blood test

Collection Method: Blood Draw

Specimen Type: Serum

Test Preparation: No preparation required

When is a Iron and Total Iron Binding Capacity test ordered?

When a doctor feels that a person's symptoms are caused by iron overload or poisoning, an iron and TIBC test, as well ferritin assays, may be done. These may include the following:

  • Joint discomfort
  • Weakness and exhaustion
  • Energy deficiency
  • Pain in the abdomen
  • Suffering from a lack of sexual desire
  • Problems with the heart

When a child is suspected of ingesting too many iron tablets, a serum iron test is required to detect the poisoning and to determine its severity.

A doctor may also request iron and TIBC when the results of a standard CBC test are abnormal, such as a low hematocrit or hemoglobin, or when a doctor suspects iron deficiency based on signs and symptoms such as:

  • Chronic tiredness/fatigue
  • Dizziness
  • Weakness
  • Headaches
  • Skin that is pale

What does a Iron and Total Iron Binding Capacity blood test check for?

Iron is a necessary ingredient for survival. It is a vital component of hemoglobin, the protein in red blood cells that binds and releases oxygen in the lungs and throughout the body. It is required in small amounts to help form normal red blood cells and is a critical part of hemoglobin, the protein in RBCs that binds oxygen in the lungs and releases it as blood circulates to other parts of the body.

By detecting numerous components in the blood, iron tests are ordered to determine the quantity of iron in the body. These tests are frequently ordered at the same time, and the data are analyzed together to determine the diagnosis and/or monitor iron deficiency or overload.

The level of iron in the liquid component of the blood is measured by serum iron.

Total iron-binding capacity is a measurement of all the proteins in the blood that may bind to iron, including transferrin.

The percentage of transferrin that has not yet been saturated is measured by the UIBC. Transferrin levels are also reflected in the UIBC.

Low iron levels can cause anemia, resulting in a decrease in the production of microcytic and hypochromic RBCs. Large amounts of iron, on the other hand, might be hazardous to the body. When too much iron is absorbed over time, iron compounds build up in tissues, particularly the liver, heart, and pancreas.

Normally, iron is absorbed from food and distributed throughout the body by binding to transferrin, a liver protein. About 70% of the iron delivered is used in the synthesis of hemoglobin in red blood cells. The rest is stored as ferritin or hemosiderin in the tissues, with minor amounts being utilized to make other proteins like myoglobin and enzymes.

Insufficient intake, limited absorption, or increased dietary requirements, as observed during pregnancy or with acute or chronic blood loss, are all signs of iron deficiency. Excessive intake of iron pills can cause acute iron overload, especially in children. Excessive iron intake, genetic hemochromatosis, multiple blood transfusions, and a few other disorders can cause chronic iron overload.

Lab tests often ordered with a Iron and Total Iron Binding Capacity test:

  • Complete Blood Count
  • Ferritin
  • Transferrin
  • Zinc Protoporphyrin

Conditions where a Iron and Total Iron Binding Capacity test is recommended:

  • Anemia
  • Hemochromatosis

How does my health care provider use a Iron and Total Iron Binding Capacity test?

The amount of circulating iron in the blood, the capacity of the blood to carry iron, and the amount of stored iron in tissues can all be determined by ordering one or more tests. Testing can also assist distinguish between different types of anemia

The level of iron in the blood is measured by serum iron.

Total iron-binding capacity is a measurement of all the proteins in the blood that may bind to iron, including transferrin. The TIBC test is a useful indirect assessment of transferrin because it is the predominant iron-binding protein. In response to the requirement for iron, the body generates transferrin. Transferrin levels rise when iron levels are low, and vice versa. About one-third of the binding sites on transferrin are used to transport iron in healthy humans.

The reserve capacity of transferrin, or the part of transferrin that has not yet been saturated, is measured by UIBC. Transferrin levels are also reflected in the UIBC.

The iron test result, as well as TIBC or UIBC, are used to calculate transferrin saturation. It represents the proportion of transferrin that is iron-saturated.

Ferritin is the major storage protein for iron inside cells, and serum ferritin represents the quantity of stored iron in the body.

These tests are frequently ordered together, and the results can assist the doctor figure out what's causing the iron deficit or overload.

Additional information about iron

A balance between the quantity of iron received into the body and the amount of iron lost is required to maintain normal iron levels. Because a tiny quantity of iron is lost each day, a deficiency will develop if too little iron is consumed. In healthy persons, there is usually enough iron to prevent iron deficiency and/or iron deficiency anemia, unless they eat a bad diet. There is a greater need for iron in some circumstances. People who have persistent gut bleeding or women who have heavy menstrual periods lose more iron than they should and can develop iron deficiency. Females who are pregnant or breastfeeding lose iron to their babies and may develop an iron shortage if they do not consume enough supplemental iron. Children may require additional iron, especially during periods of rapid growth, and may suffer iron shortage.

Low serum iron can also arise when the body is unable to adequately utilize iron. The body cannot correctly utilize iron to generate additional red cells in many chronic disorders, particularly malignancies, autoimmune diseases, and chronic infections. As a result, transferrin production slows, serum iron levels drop because little iron is absorbed from the stomach, and ferritin levels rise. Malabsorption illnesses like sprue syndrome can cause iron deficiency.

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.


Description: A Lipid Panel is a blood test that measures your cholesterol levels to evaluate your risk of cardiovascular disease. 

Also Known As: Lipid Profile Test, Lipid Test, Cholesterol Profile Test, Cholesterol Panel Test, Cholesterol Test, Coronary Risk Panel Test, lipid blood test 

Collection Method: Blood Draw 

Specimen Type: Serum 

Test Preparation: Patient should be fasting 9-12 hours prior to collection.

When is a Lipid Panel test ordered?  

A fasting lipid profile should be done about every five years in healthy persons who have no additional risk factors for heart disease. A single total cholesterol test, rather than a complete lipid profile, may be used for initial screening. If the screening cholesterol test result is high, a lipid profile will almost certainly be performed. 

More regular testing with a full lipid profile is indicated if other risk factors are present or if earlier testing revealed a high cholesterol level. 

Other risk factors, in addition to high LDL cholesterol, include: 

  • Smoking 
  • Obesity or being overweight 
  • Unhealthy eating habits 
  • Not getting enough exercise and being physically inactive 
  • Older age 
  • Having hypertension 
  • Premature heart disease in the family 
  • Having experienced a heart attack or having pre-existing heart disease 

Diabetes or pre-diabetes is a condition in which a person has High HDL is a "negative risk factor," and its existence permits one risk factor to be removed from the total. 

The American Academy of Pediatrics recommends routine lipid testing for children and young adults. Children and teenagers who are at a higher risk of developing heart disease as adults should be screened with a lipid profile earlier and more frequently. A family history of heart disease or health problems such as diabetes, high blood pressure, or being overweight are some of the risk factors, which are comparable to those in adults. According to the American Academy of Pediatrics, high-risk children should be examined with a fasting lipid profile between the ages of 2 and 8. 

A lipid profile can also be done at regular intervals to assess the effectiveness of cholesterol-lowering lifestyle changes like diet and exercise, as well as pharmacological therapy like statins. 

What does a Lipid Panel blood test check for? 

Lipids are a class of fats and fat-like compounds that are essential components of cells and energy sources. The level of certain lipids in the blood is measured by a lipid profile. 

Lipoprotein particles transport two key lipids, cholesterol, and triglycerides, through the bloodstream. Protein, cholesterol, triglyceride, and phospholipid molecules are all present in each particle. High-density lipoproteins, low-density lipoproteins, and very low-density lipoproteins are the three types of particles assessed with a lipid profile. 

It's critical to keep track of and maintain optimal levels of these lipids in order to stay healthy. While the body creates the cholesterol required for normal function, some cholesterol is obtained from the diet. A high amount of cholesterol in the blood can be caused by eating too many foods high in saturated fats and trans fats or having a hereditary tendency. The excess cholesterol may form plaques on the inside walls of blood vessels. Plaques can constrict or block blood channel openings, causing artery hardening and raising the risk of a variety of health problems, including heart disease and stroke. Although the explanation for this is unknown, a high level of triglycerides in the blood is linked to an increased risk of developing cardiovascular disease. 

A lipid profile consists of the following elements: 

  • Cholesterol total 
  • HDL Cholesterol -?commonly referred to as "good cholesterol" since it eliminates excess cholesterol from the body and transports it to the liver for elimination. 
  • LDL Cholesterol -?commonly referred to as "bad cholesterol" because it deposits excess cholesterol in the walls of blood arteries, contributing to atherosclerosis. 
  • Triglycerides 

Lab tests often ordered with a Lipid Panel test:

  • CBC (Blood Count Test) with Smear Review
  • Comprehensive Metabolic Panel
  • Direct LDL
  • VLDL
  • Lp-PLA2
  • Apolipoprotein A1
  • Apolipoprotein B
  • Lipoprotein (a)
  • Lipoprotein Fractionation Ion Mobility (LDL Particle Testing)

Conditions where a Lipid Panel test is recommended:

  • Hypertension
  • Cardiovascular Disease
  • Heart Disease
  • Stroke

Commonly Asked Questions: 

How does my health care provider use a Lipid Panel test? 

The lipid profile is used as part of a cardiac risk assessment to help determine an individual's risk of heart disease and, if there is a borderline or high risk, to help make treatment options. 

Lipids are a class of fats and fat-like compounds that are essential components of cells and energy sources. It's critical to keep track of and maintain optimal levels of these lipids in order to stay healthy. 

To design a therapy and follow-up strategy, the results of the lipid profile are combined with other recognized risk factors for heart disease. Treatment options may include lifestyle changes such as diet and exercise, as well as lipid-lowering drugs such as statins, depending on the results and other risk factors. 

A normal lipid profile test measures the following elements: 

  • Total cholesterol is a test that determines how much cholesterol is present in all lipoprotein particles. 

  • HDL Cholesterol — measures hdl cholesterol in particles, sometimes referred to as "good cholesterol" since it eliminates excess cholesterol and transports it to the liver for elimination. 

  • LDL Cholesterol – estimates the cholesterol in LDL particles; sometimes known as "bad cholesterol" since it deposits excess cholesterol in blood vessel walls, contributing to atherosclerosis. The amount of LDL Cholesterol is usually estimated using the total cholesterol, HDL Cholesterol, and triglycerides readings. 

  • Triglycerides – triglycerides are measured in all lipoprotein particles, with the highest concentration in very-low-density lipoproteins. 

  • As part of the lipid profile, several extra information may be presented. The results of the above-mentioned tests are used to determine these parameters. 

  • VLDL Cholesterol — derived using triglycerides/5; this calculation is based on the typical VLDL particle composition. 

  • Non-HDL Cholesterol - the result of subtracting total cholesterol from HDL Cholesterol. 

  • Cholesterol/HDL ratio — total cholesterol to HDL Cholesterol ratio computed. 

An expanded profile may include the amount and concentration of low-density lipoprotein particles. Rather than assessing the amount of LDL cholesterol, this test counts the number of LDL particles. This figure is thought to more accurately reflect the risk of heart disease in some persons. 

What do my Lipid Panel test results mean? 

Healthy lipid levels, in general, aid in the maintenance of a healthy heart and reduce the risk of heart attack or stroke. A health practitioner would analyze the results of each component of a lipid profile, as well as other risk factors, to assess a person's total risk of coronary heart disease, if therapy is required, and, if so, which treatment will best serve to reduce the person's risk of heart disease. 

The Adult Treatment Panel III of the National Cholesterol Education Program published guidelines for measuring lipid levels and selecting treatment in 2002. The American College of Cardiology and the American Heart Association announced updated cholesterol therapy guidelines in 2013 to minimize the risk of cardiovascular disease in adults. These guidelines suggest a different treatment method than the NCEP guidelines. Cholesterol-lowering medications are now chosen based on the 10-year risk of atherosclerotic cardiovascular disease and other criteria, rather than on LDL Cholesterol or non-HDL Cholesterol objectives. 

The revised guidelines include an evidence-based risk calculator for ASCVD that may be used to identify people who are most likely to benefit from treatment. It's for adults between the ages of 40 and 79 who don't have a heart condition. The computation takes into account a number of characteristics, including age, gender, race, total cholesterol, HDL Cholesterol, blood pressure, diabetes, and smoking habits. The new guidelines also suggest comparing therapeutic response to LDL Cholesterol baseline readings, with decrease criteria varying depending on the degree of lipid-lowering medication therapy. 

Unhealthy lipid levels, as well as the presence of additional risk factors like age, family history, cigarette smoking, diabetes, and high blood pressure, may indicate that the person being examined needs to be treated. 

The NCEP Adult Treatment Panel III guidelines specify target LDL cholesterol levels based on the findings of lipid testing and these other main risk factors. Individuals with LDL Cholesterol levels over the target limits will be treated, according to the guidelines. 

According to the American Academy of Pediatrics, screening youths with risk factors for heart disease with a full, fasting lipid panel is advised. Fasting is not required prior to lipid screening in children who do not have any risk factors. For non-fasting lipid screening, non-high-density lipoprotein cholesterol is the preferred test. Non HDL Cholesterol is computed by subtracting total cholesterol and HDL Cholesterol from total cholesterol and HDL Cholesterol. 

Is there anything else I should know? 

The measurement of triglycerides in people who haven't fasted is gaining popularity. Because most of the day, blood lipid levels reflect post-meal levels rather than fasting levels, a non-fasting sample may be more representative of the "usual" circulating level of triglyceride. However, because it is still unclear how to interpret non-fasting levels for assessing risk, the current recommendations for fasting before lipid tests remain unchanged. 

A fasting lipid profile is usually included in a routine cardiac risk assessment. In addition, research into the utility of additional non-traditional cardiac risk markers, such as Lp-PLA2, is ongoing. A health care provider may use one or more of these markers to help determine a person's risk, but there is no consensus on how to use them and they are not widely available. 

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.


Description: A Lipid Panel is a blood test that measures your cholesterol levels to evaluate your risk of cardiovascular disease.

Also Known As: Lipid Profile Test, Lipid Test, Cholesterol Profile Test, Cholesterol Panel Test, Cholesterol Test, Coronary Risk Panel Test, lipid blood test, Lipid w/Ratios Test, Cholesterol Ratio test, blood cholesterol Test

Collection Method: Blood Draw

Specimen Type: Serum

Test Preparation: Patient should be fasting 9-12 hours prior to collection.

When is a Lipid Panel with Ratios test ordered?

A fasting lipid profile should be done about every five years in healthy persons who have no additional risk factors for heart disease. A single total cholesterol test, rather than a complete lipid profile, may be used for initial screening. If the screening cholesterol test result is high, a lipid profile will almost certainly be performed.

More regular testing with a full lipid profile is indicated if other risk factors are present or if earlier testing revealed a high cholesterol level.

Other risk factors, in addition to high LDL cholesterol, include:

  • Smoking
  • Obesity or being overweight
  • Unhealthy eating habits
  • Not getting enough exercise and being physically inactive
  • Older age
  • Having hypertension
  • Premature heart disease in the family
  • Having experienced a heart attack or having pre-existing heart disease

Diabetes or pre-diabetes is a condition in which a person has High HDL is a "negative risk factor," and its existence permits one risk factor to be removed from the total.

The American Academy of Pediatrics recommends routine lipid testing for children and young adults. Children and teenagers who are at a higher risk of developing heart disease as adults should be screened with a lipid profile earlier and more frequently. A family history of heart disease or health problems such as diabetes, high blood pressure, or being overweight are some of the risk factors, which are comparable to those in adults. According to the American Academy of Pediatrics, high-risk children should be examined with a fasting lipid profile between the ages of 2 and 8.

A lipid profile can also be done at regular intervals to assess the effectiveness of cholesterol-lowering lifestyle changes like diet and exercise, as well as pharmacological therapy like statins.

What does a Lipid Panel with Ratios blood test check for?

Lipids are a class of fats and fat-like compounds that are essential components of cells and energy sources. The level of certain lipids in the blood is measured by a lipid profile.

Lipoprotein particles transport two key lipids, cholesterol and triglycerides, through the bloodstream. Protein, cholesterol, triglyceride, and phospholipid molecules are all present in each particle. High-density lipoproteins, low-density lipoproteins, and very low-density lipoproteins are the three types of particles assessed with a lipid profile.

It's critical to keep track of and maintain optimal levels of these lipids in order to stay healthy. While the body creates the cholesterol required for normal function, some cholesterol is obtained from the diet. A high amount of cholesterol in the blood can be caused by eating too many foods high in saturated fats and trans fats or having a hereditary tendency. The excess cholesterol may form plaques on the inside walls of blood vessels. Plaques can constrict or block blood channel openings, causing artery hardening and raising the risk of a variety of health problems, including heart disease and stroke. Although the explanation for this is unknown, a high level of triglycerides in the blood is linked to an increased risk of developing cardiovascular disease.

A lipid profile consists of the following elements:

  • Cholesterol total
  • HDL Cholesterol - commonly referred to as "good cholesterol" since it eliminates excess cholesterol from the body and transports it to the liver for elimination.
  • LDL Cholesterol - commonly referred to as "bad cholesterol" because it deposits excess cholesterol in the walls of blood arteries, contributing to atherosclerosis.
  • Triglycerides
  • Ratio of LDL to HDL cholesterol

Lab tests often ordered with a Lipid Panel with Ratios test:

  • CBC (Blood Count Test) with Smear Review
  • Comprehensive Metabolic Panel
  • Direct LDL
  • VLDL
  • Lp-PLA2
  • Apolipoprotein A1
  • Apolipoprotein B
  • Lipoprotein (a)
  • Lipoprotein Fractionation Ion Mobility (LDL Particle Testing)

Conditions where a Lipid Panel with Ratios test is recommended:

  • Hypertension
  • Cardiovascular Disease
  • Heart Disease
  • Stroke

Commonly Asked Questions:

How does my health care provider use a Lipid Panel with Ratios test?

The lipid profile is used as part of a cardiac risk assessment to help determine an individual's risk of heart disease and, if there is a borderline or high risk, to help make treatment options.

Lipids are a class of fats and fat-like compounds that are essential components of cells and energy sources. It's critical to keep track of and maintain optimal levels of these lipids in order to stay healthy.

To design a therapy and follow-up strategy, the results of the lipid profile are combined with other recognized risk factors for heart disease. Treatment options may include lifestyle changes such as diet and exercise, as well as lipid-lowering drugs such as statins, depending on the results and other risk factors.

A normal lipid profile test measures the following elements:

  • Total cholesterol is a test that determines how much cholesterol is present in all lipoprotein particles.
  • HDL Cholesterol — measures hdl cholesterol in particles, sometimes referred to as "good cholesterol" since it eliminates excess cholesterol and transports it to the liver for elimination.
  • LDL Cholesterol – estimates the cholesterol in LDL particles; sometimes known as "bad cholesterol" since it deposits excess cholesterol in blood vessel walls, contributing to atherosclerosis. The amount of LDL Cholesterol is usually estimated using the total cholesterol, HDL Cholesterol, and triglycerides readings.
  • Triglycerides – triglycerides are measured in all lipoprotein particles, with the highest concentration in very-low-density lipoproteins.
  • As part of the lipid profile, several extra information may be presented. The results of the above-mentioned tests are used to determine these parameters.
  • VLDL Cholesterol — derived using triglycerides/5; this calculation is based on the typical VLDL particle composition.
  • Non-HDL Cholesterol - the result of subtracting total cholesterol from HDL Cholesterol.
  • Cholesterol/HDL ratio — total cholesterol to HDL Cholesterol ratio computed.

An expanded profile may include the amount and concentration of low-density lipoprotein particles. Rather than assessing the amount of LDL cholesterol, this test counts the number of LDL particles. This figure is thought to more accurately reflect the risk of heart disease in some persons.

What do my Lipid Panel test results mean?

Healthy lipid levels, in general, aid in the maintenance of a healthy heart and reduce the risk of heart attack or stroke. A health practitioner would analyze the results of each component of a lipid profile, as well as other risk factors, to assess a person's total risk of coronary heart disease, if therapy is required, and, if so, which treatment will best serve to reduce the person's risk of heart disease.

The Adult Treatment Panel III of the National Cholesterol Education Program published guidelines for measuring lipid levels and selecting treatment in 2002. The American College of Cardiology and the American Heart Association announced updated cholesterol therapy guidelines in 2013 to minimize the risk of cardiovascular disease in adults. These guidelines suggest a different treatment method than the NCEP guidelines. Cholesterol-lowering medications are now chosen based on the 10-year risk of atherosclerotic cardiovascular disease and other criteria, rather than on LDL-C or non-HDL-C objectives.

The revised guidelines include an evidence-based risk calculator for ASCVD that may be used to identify people who are most likely to benefit from treatment. It's for adults between the ages of 40 and 79 who don't have a heart condition. The computation takes into account a number of characteristics, including age, gender, race, total cholesterol, HDL-C, blood pressure, diabetes, and smoking habits. The new guidelines also suggest comparing therapeutic response to LDL-C baseline readings, with decrease criteria varying depending on the degree of lipid-lowering medication therapy.

Unhealthy lipid levels, as well as the presence of additional risk factors like age, family history, cigarette smoking, diabetes, and high blood pressure, may indicate that the person being examined needs to be treated.

The NCEP Adult Treatment Panel III guidelines specify target LDL cholesterol levels based on the findings of lipid testing and these other main risk factors. Individuals with LDL-C levels over the target limits will be treated, according to the guidelines.

According to the American Academy of Pediatrics, screening youths with risk factors for heart disease with a full, fasting lipid panel is advised. Fasting is not required prior to lipid screening in children who do not have any risk factors. For non-fasting lipid screening, non-high-density lipoprotein cholesterol is the preferred test. Non-HDL-C is computed by subtracting total cholesterol and HDL-C from total cholesterol and HDL-C.

Is there anything else I should know?

The measurement of triglycerides in people who haven't fasted is gaining popularity. Because most of the day, blood lipid levels reflect post-meal levels rather than fasting levels, a non-fasting sample may be more representative of the "usual" circulating level of triglyceride. However, because it is still unclear how to interpret non-fasting levels for assessing risk, the current recommendations for fasting before lipid tests remain unchanged.

A fasting lipid profile is usually included in a routine cardiac risk assessment. In addition, research into the utility of additional non-traditional cardiac risk markers, such as Lp-PLA2, is ongoing. A health care provider may use one or more of these markers to help determine a person's risk, but there is no consensus on how to use them and they are not widely available.

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.


Thyroglobulin (TG) is a secretory product only of the thyroid gland. The major clinical use of serum TG measurement is to monitor, but not to diagnose, patients with well-differentiated thyroid cancers. The measurement of thyroglobulin, after thyroidectomy and ablation of the thyroid gland, is useful to determine metastasis. Deficient TG synthesis is observed in infants with goitrous hypothyroidism. With immunometric assays (sandwich assays), TGAB interference typically produces inappropriately low TG results, most likely caused by endogenous TG immune complexes that block one or more of the reagent Ab from binding endogenous TG.


Guide to the Thyroid and Thyroid Diseases

Your thyroid is a small butterfly-shaped gland on the base of your throat. The thyroid plays an essential role in helping to control the metabolism of your body by producing thyroid hormones, mainly triiodothyronine (T3) and thyroxine (T4). They are substances that travel through your blood to all parts of your body. Thyroid hormones inform the cells within your body how quickly to produce proteins and use energy. Calcitonin is also made by the thyroid gland. Calcitonin is a hormone that helps with regulating the levels of calcium inside the blood through inhibiting re-absorption (breakdown) of bone as well as increasing the elimination of calcium through the kidneys.     

The body features an elaborate feedback system for controlling the amounts of T3 and T4 inside the blood. Whenever the blood levels of these hormones fall, thyrotropin-releasing hormone is released by the hypothalamus. This, in turn, causes thyroid-stimulating hormone (TSH) to be released by the pituitary gland. The thyroid gland is stimulated by TSH to secrete and produce T3 and T4 (primarily). Whenever the system is functioning correctly, thyroid production turns off and on to maintain thyroid hormone levels that are relatively stable. 

Inside of the thyroid, a majority of the T4 is bound to the thyroglobulin protein and stored away. Whenever necessary, more T4 is produced by the thyroid gland and/or some of the stored amount is released. Inside the blood, most of the T3 and T4 are bound to thyroxine-binding globulin (TBG) protein and are inactive. There are small, unbound amounts, called free T3 and free T4, that are the active forms of these hormones. T4 gets converted into T3 inside of the liver as well as other tissues. The primary responsibility of T3 is to control body function rates.

Thyroid diseases are mainly conditions affecting how much thyroid hormones are produced. The American Thyroid Association estimates that there are 20 million Americans who some type of thyroid disease, and around 60% of people with thyroid disease are not aware of it. It is more likely for women to have thyroid issues than men, with 1 out of 8 women developing a thyroid disorder at some point in her life. Below is a list of the most common types of thyroid disorders.

Types of Abnormal Thyroid Functioning

Some of the diseases of abnormal thyroid functioning include the following:

Hypothyroidism: this refers to a condition where there is an insufficient amount of thyroid hormone and body functions slow down. Some of the main symptoms include menstrual irregularity within women, fatigue, hair loss, puffy skin, cold intolerance, constipation, dry skin, and weight gain. Myxedema, which is severe untreated hypothyroidism, may lead to coma, seizures, and heart failure. In children, hypothyroidism may delay sexual development and stunt growth. Specific hypothyroidism types include the following: 

Congenital hypothyroidism: a condition that affects babies from birth caused by insufficient thyroid hormone; is mainly due to when a thyroid gland is partially developed, missing, or when it is in part of the body that is abnormal. The remainder of cases is either due to an enlarged or normal-sized thyroid that isn’t functioning correctly or producing enough thyroid hormone. When this condition is left untreated, it may cause delays in intellectual and physical development. In the US, hypothyroidism testing is done as part of blood screening programs for newborns because early detection, as well as treatment, helps to minimize long-term damage to babies. 

Hashimoto thyroiditis: in the US, this is the most common type of hypothyroidism. It is a chronic autoimmune condition where the thyroid is targeted by the immune system, which causes damage and inflammation and produces autoantibodies. With Hashimoto thyroiditis, thyroid hormones are produced in lower quantities.

Iodine deficiency: when the element of iodide is lacking in the body, it diminishes the thyroid gland’s ability to produce enough thyroid hormone. There are three iodides in T3 and four iodides in T4. Throughout the environment, iodine is present. However, most iodine is contained in seaweed and seawater. Individuals who reside in countries with limited access to the ocean frequently suffer from iodine deficiency unless they consume food supplemented with iodine. Iodide is fortunately used for fighting bacterial growth in various foods (like iodized salt) and many dietary supplements as well.

Hyperthyroidism: excessive thyroid hormone, also referred to as “overactive thyroid.” Body functions are accelerated, and symptoms include weakness, tremors within the hands, difficulty sleeping, weight loss, anxiety, increased heart rate, and diarrhea sometimes. There might be puffiness surrounding the eyes, irritation, dryness, and bulging eyes in some cases. The person who is affected might experience visual disturbances and light sensitivity. Since the eyes might not move in a normal way, the individual might look like they are staring. 

Specific kinds of hyperthyroidism include the following:

Graves disease: this is the most common cause of hyperthyroidism. This is a chronic autoimmune disorder where the immune system of the affected individual produces antibodies that act like TSH, which stimulates the thyroid to make excessive thyroid hormone amounts.

Thyroid tumor: a small benign tumor might become insensitive to low TSH negative feedback and continuing producing thyroid hormone in excessive amounts.

Abnormal thyroid stimulation: when there is a tumor in the cells producing TSH, it may result in the excessive production of thyroid hormone. The hormone called human chorionic gonadotropin (hCG), which supports fetus growth during pregnancy, can act like TSH and produce hyperthyroidism in pregnant women if they have very high hCG levels.

Goiter: a visible enlargement of the thyroid gland. This condition in the past was common and caused by an iodine deficiency. However, now that food is supplemented with iodine, there are significantly fewer dietary-related goiter incidents in the US. However, in other regions of the world, iodine-related goiters are common still and in some countries are the most common cause of hypothyroidism. Goiters can compress critical structures within the neck, which include the esophagus and trachea. That compression can make it hard to swallow and breathe. Goiters can be caused by any diseases that are listed above. Thyroid hormone resistance syndrome is a rare cause and a mutation within the thyroid hormone receptor that reduces the functioning of the thyroid hormone.

Thyroiditis: an inflamed thyroid gland; it can be associated with either hyper- or hypothyroidism. It can be quite painful and feel like a sore throat, and it can also be painless. Thyroiditis can be caused by several things such as exposure to toxic chemicals, infection, or autoimmune disorders (especially if you have Hashimoto thyroiditis). The cause of thyroiditis can also be unknown. Depending on what the cause is, it may be chronic, transient, or acute.

Diseases that may be presented as thyroid tumors include the following:

Thyroid nodule: this is a small lump located on a thyroid gland. It can be either a fluid-filled or solid cyst. The nodules are very common, and a vast majority are harmless. However, occasionally, a thyroid nodule may be cancerous and require treatment.

Thyroid cancer: this disease is relatively common and has seen an increase in the number of incidents over the past couple of decades. The American Cancer Society estimates that around 63,000 new cases are diagnosed in the US each year, which makes it the 8th most common form of cancer as well as the fastest-growing form. Thyroid cancer comes in form main types:

Papillary thyroid cancer: makes up around 80% of all thyroid cancer cases. More women are affected by this type of thyroid cancer than men. It is also more commonly found in younger individuals.

Follicular thyroid cancer: makes up around 15% of all thyroid cancers. It is a more aggressive form of cancer, and older women tend to be at increased risk.

Anaplastic thyroid cancer: makes up around 2% of all thyroid cancers and tends to be found mostly in older women. It is hard to treat and tends to be aggressive.

Medullary thyroid cancer (MTC): makes up around 3% of all thyroid cancers. It is malignant and may spread past the thyroid. It can be hard to treat if not detected early. Excess calcitonin is produced by MTC and might be found by itself or linked along with other types of endocrine cancers within a syndrome, which is referred to as the multiple endocrine neoplasia syndrome. Cells that produce calcitonin are different from cells that produce thyroid hormone. They can increase in number, which results in the c-cell hyperplasia disorder. The condition is benign and produces excess calcitonin as well. It might progress into becoming medullary thyroid cancer sometimes.

Lymphoma is a tumor that is made up of lymphocytes (these are cells that produce immunity out of viruses and bacteria. It can take place inside the thyroid also.

Laboratory Tests

Usually, the first test that will be ordered by a healthcare practitioner for detecting thyroid dysfunction will be a thyroid-stimulating hormone (TSH) test. If there is an abnormal TSH level, usually a free thyroxine test will be ordered by the healthcare practitioner so that the diagnosis can be confirmed.

T4 is not real soluble inside the blood. Therefore, serum proteins carry it. A small percentage of overall T4 isn’t bound to protein. That fraction is biologically active. Laboratories in the past estimated free T4 concentrations by measuring total T4 and determining binding protein levels. However, these days, it is a lot more common for free T4 to be estimated by laboratories directly through the use of immunoassay. 

At times, tests for triiodothyronine (T3), which is the other primary thyroid hormone, might also be ordered, or all the tests might be ordered as one thyroid panel.

TSH – Used for monitoring thyroid disorder treatments, screening newborn babies for hypothyroidism, and testing for both hyperthyroidism and hypothyroidism.

Free T4 – Used for monitoring thyroid disease treatment, screening newborn babies for hypothyroidism, and testing for both hyperthyroidism and hypothyroidism.

Free T3 – Mainly used for testing hyperthyroidism, particularly whenever free T4 isn’t elevated. Whenever individuals are iodine-deficient, more T3 is made by the thyroid than T4.

Other tests that might be conducted include the following:

Total T3 and total T4 might be needed still in certain rare cases.

Thyroid antibodies – Help with identifying autoimmune thyroid conditions and differentiating various kinds of thyroiditis.

Thyroid peroxidase (TPO) antibody – This is an autoimmune thyroid disease marker. It may be detected in Hashimoto thyroiditis or Grave’s disease. It can be especially useful with early Hashimoto thyroiditis since TSH is elevated while the remaining thyroid still can maintain healthy levels of free T4.

Thyroglobulin (TG) antibody – This is a marker for both Hashimoto thyroiditis and Grave’s disease. Thyroglobulin, where thyroid hormone is stored, is targeted by this antibody.

TSHR (Thyroid-stimulating hormone receptor antibodies – This is a Graves disease marker. There are two different ways that it can be measured:

TBII (Thyroid binding inhibitory immunoglobulin) -This assay the serum of a patient’s ability to block TSH from binding with receptors.

TSI (Thyroid-stimulating immunoglobulin) – This assay measures thyroid cell stimulation inside of a culture dish.

Some Grave’s disease patients have antibodies that only can be detected by one of the two approaches. Autoimmune antibodies of the TSH receptor may rarely cause hypothyroidism (instead of hyperthyroidism).

Calcitonin – Helps with detecting excessive production of calcitonin, which may happen with medullary and C-cell hyperplasia thyroid cancer.