TH-2. Thyroid Health

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Triiodothyronine

T3, Total

Triiodothyronine (T3) is a thyroid hormone. It plays an important role in the body's control of metabolism.

Also known as: Free T3, FT3, T3 Free

T3, Free

This test measures the amount of triiodothyronine, or T3, in the blood.

Also known as: T4 Thyroxine Total

Free T4 Index (T7)

FTI stands for the Free Thyroxine Index and is also sometimes referred to as T7. It is a calculated value determined from the T3 uptake test and total T4 test and provides an estimate of the level of free T4 in the blood.

T4 (Thyroxine), Total

This test measures the amount of thyroxine, or T4, in the blood. T4 is one of two major hormones produced by the thyroid gland. The total T4 test is used to help diagnose hyperthyroidism and hypothyroidism. It is a useful test but can be affected by the amount of protein available in the blood to bind to the hormone.

Also known as: Free T4, FT4, T4 Free

T4, Free

The free T4 test is not affected by protein levels. Since free T4 is the active form of thyroxine, the free T4 test is may be a more accurate reflection of thyroid hormone function.

Also known as: Thyroid Stimulating Hormone, Thyroid Stimulating Hormone (TSH), Thyrotropin


A TSH test is a lab test that measures the amount of thyroid stimulating hormone (TSH) in your blood. TSH is produced by the pituitary gland. It tells the thyroid gland to make and release thyroid hormones into the blood.


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The TH-2. Thyroid Health panel contains 5 tests with 7 biomarkers.

Brief Description: The TH-2 Thyroid Health panel is a comprehensive set of tests designed to evaluate thyroid function more extensively than basic screenings. It includes assessments of both bound and unbound thyroid hormones, providing a detailed picture of thyroid activity and metabolism.

Collection Method: Blood Draw

Specimen Type: Serum

Test Preparation: Specifc to TSH: Specimen collection after fluorescein dye angiography should be delayed for at least 3 days. For patients on hemodialysis, specimen collection should be delayed for 2 weeks.

According to the assay manufacturer Siemens: "Samples containing fluorescein can produce falsely depressed values when tested with the Advia Centaur TSH3 Ultra assay."

When and Why the TH-2 Thyroid Health Panel May Be Ordered

Healthcare providers may order the TH-2 Thyroid Health panel for individuals showing symptoms of thyroid dysfunction, such as unexplained weight changes, mood swings, temperature sensitivities, or energy level fluctuations. It's particularly useful for diagnosing and monitoring thyroid conditions and for guiding treatment decisions.

What the TH-2 Thyroid Health Panel Checks For

  • T3 Total: Measures the total amount of triiodothyronine in the blood, including both bound and free T3, providing an overview of the body's metabolic activity.
  • T3 Free: Assesses the unbound, active form of T3, offering insights into the thyroid's functional status and its impact on metabolism.
  • T4 Total: Evaluates the total thyroxine levels, encompassing both bound and free T4, to assess the thyroid gland's output.
  • T4 Free: Measures the unbound thyroxine, providing a direct indicator of the hormone available for physiological actions.
  • Thyroid Stimulating Hormone (TSH): A central regulator of thyroid function, with its levels reflecting the pituitary gland's response to thyroid hormone levels in the blood.

Getting a Deeper Understanding of Your Thyroid Health

While the TH-2 panel offers a thorough assessment of thyroid hormone levels, further evaluation is possible with advanced panels:

Conditions or Diseases the TH-2 Thyroid Health Panel Can Check For

The TH-2 Thyroid Health panel can help diagnose various thyroid conditions, including hypothyroidism and hyperthyroidism, by assessing the levels of thyroid hormones and TSH. It can also aid in evaluating the efficacy of thyroid hormone replacement therapy.

Use of TH-2 Thyroid Health Panel Results by Healthcare Professionals

Healthcare professionals use the results from the TH-2 Thyroid Health panel to diagnose thyroid disorders, guide treatment plans, and monitor the effectiveness of treatments. The detailed thyroid hormone profile helps in understanding the thyroid gland's function and in adjusting medication dosages for optimal thyroid hormone levels.

The TH-2 Thyroid Health panel provides a comprehensive evaluation of thyroid function, offering valuable insights into the balance and metabolism of thyroid hormones. This panel is instrumental in diagnosing thyroid disorders, guiding treatment, and monitoring therapy effectiveness. For individuals requiring a more in-depth analysis, particularly to assess autoimmune involvement or complex thyroid conditions, the TH-3 and TH-4 panels offer additional markers, enhancing the ability to tailor treatment approaches and manage thyroid health effectively.

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.

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