Thyroid Health - Advanced Lab Panel Most Popular

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Reverse T3, Reverse Triiodothyronine, RT3, T3 Reverse RT3 LCMSMS, Triiodothyronine Reverse

T3 Reverse, LC/MS/MS

Reverse T3 produced in the thyroid comes from the conversion of the storage hormone T4. Your body, especially the liver, can constantly be converting T4 to RT3 as a way to get rid of any unneeded T4. In any given day approx. 40% of T4 goes to T3 and 20% of T4 goes to Reverse T3. However in any situation where your body needs to conserve energy and focus on something else, it will change the above percentages, changing the conversion of RT3 to 50% or more, and the T3 goes down, down. Examples are emotional, physical, or biological stress, such as being chronically or acutely sick (the flu, pneumonia, etc), after surgery, after a car accident or any acute injury, chronic stress causing high cortisol, being exposed to an extremely cold environment, diabetes, aging, or even being on drugs like beta blockers and amiodarone.

Also known as: Triiodothyronine

T3, Total

Triiodothyronine (T3) is a thyroid hormone. It plays an important role in the body's control of metabolism.

T3 Uptake

T3 uptake is also known as T3 Resin Uptake (T3RU) or Thyroid Uptake. It estimates how much thyroid hormone-binding proteins are available in the blood through a calculation based on levels of T3 or T4 added to a person's blood specimen.

Also known as: Free T3, FT3, T3 Free

T3, Free

This test measures the amount of triiodothyronine, or T3, in the blood.

Also known as: T4 Thyroxine Total

Free T4 Index (T7)

FTI stands for the Free Thyroxine Index and is also sometimes referred to as T7. It is a calculated value determined from the T3 uptake test and total T4 test and provides an estimate of the level of free T4 in the blood.

T4 (Thyroxine), Total

This test measures the amount of thyroxine, or T4, in the blood. T4 is one of two major hormones produced by the thyroid gland. The total T4 test is used to help diagnose hyperthyroidism and hypothyroidism. It is a useful test but can be affected by the amount of protein available in the blood to bind to the hormone.

Also known as: Free T4, FT4, T4 Free

T4, Free

The free T4 test is not affected by protein levels. Since free T4 is the active form of thyroxine, the free T4 test is may be a more accurate reflection of thyroid hormone function.

Thyroglobulin Antibodies

Measurement of thyroglobulin antibodies is useful in the diagnosis and management of a variety of thyroid disorders including Hashimoto's thyroiditis, Graves Disease and certain types of goiter.

Thyroid Peroxidase

Also known as: Thyroid Stimulating Hormone, Thyroid Stimulating Hormone (TSH), Thyrotropin


A TSH test is a lab test that measures the amount of thyroid stimulating hormone (TSH) in your blood. TSH is produced by the pituitary gland. It tells the thyroid gland to make and release thyroid hormones into the blood.


*Important Information on Lab Test Processing Times: Ulta Lab Tests is committed to informing you about the processing times for your lab tests processed through Quest Diagnostics. Please note that the estimated processing time for each test, indicated in business days, is based on data from the past 30 days across the 13 Quest Diagnostics laboratories for each test. These estimates are intended to serve as a guide and are not guarantees. Factors such as laboratory workload, weather conditions, holidays, and the need for additional testing or maintenance can influence actual processing times. We aim to offer estimates to help you plan accordingly. Please understand that these times may vary, and processing times are not guaranteed. Thank you for choosing Ulta Lab Tests for your laboratory needs.

The Thyroid Health - Advanced Lab Panel panel contains 8 tests with 11 biomarkers.

Brief Description: The Thyroid Health - Advanced Lab panel is a comprehensive diagnostic tool designed to offer a detailed evaluation of thyroid function and associated autoimmunity. It comprises eight key tests: T3 Reverse, T3 Total, T3 Uptake, T3 Free, T4 Total, T4 Free, Thyroid Peroxidase Antibodies, Thyroglobulin Antibodies, and Thyroid Stimulating Hormone (TSH). This panel goes beyond basic thyroid function testing to include assessments of reverse T3 levels and thyroid antibodies, providing a more comprehensive view of thyroid health.

Collection Method: Blood Draw

Specimen Type: Serum

Test Preparation: Specifc to TSH: Specimen collection after fluorescein dye angiography should be delayed for at least 3 days. For patients on hemodialysis, specimen collection should be delayed for 2 weeks.

According to the assay manufacturer Siemens: "Samples containing fluorescein can produce falsely depressed values when tested with the Advia Centaur TSH3 Ultra assay."

When and Why the Thyroid Health - Advanced Lab Panel May Be Ordered

The Thyroid Health - Advanced Lab panel is typically ordered when healthcare providers suspect complex thyroid issues, autoimmune thyroid diseases, or when initial thyroid function tests yield inconclusive results. It is especially valuable when patients present with a combination of thyroid-related symptoms and signs of autoimmunity, such as Hashimoto's thyroiditis or Graves' disease. This panel helps in diagnosing and managing thyroid disorders with autoimmune components.

What the Thyroid Health - Advanced Lab Panel Checks For

  1. T3 Reverse: Measures reverse T3, a less active form of T3, which can indicate thyroid dysfunction and potential metabolic issues.

  2. T3 Total: Measures the total amount of triiodothyronine (T3) hormone in the blood, including both bound and free forms. T3 plays a crucial role in regulating metabolism and energy production.

  3. T3 Uptake: Assesses the availability of binding proteins for T3, providing information on the capacity to transport T3 in the bloodstream.

  4. T3 Free: Specifically measures the free, unbound T3 hormone, which is biologically active and available for use by the body's cells.

  5. T4 Total: Measures the total amount of thyroxine (T4) hormone in the blood, including both bound and free T4. T4 is a key thyroid hormone involved in regulating metabolism.

  6. T4 Free: Specifically measures the free, unbound T4 hormone, which is the biologically active form available for cellular uptake.

  7. Thyroid Peroxidase Antibodies: Detects antibodies against thyroid peroxidase, an enzyme involved in thyroid hormone production. Elevated levels may indicate autoimmune thyroid diseases like Hashimoto's thyroiditis.

  8. Thyroglobulin Antibodies: Measures antibodies against thyroglobulin, a protein found in the thyroid gland. Elevated levels may suggest autoimmune thyroid conditions.

  9. Thyroid Stimulating Hormone (TSH): Produced by the pituitary gland, TSH regulates the thyroid's production of T3 and T4. It helps evaluate the overall thyroid status and can indicate an overactive or underactive thyroid.

Getting a Deeper Understanding of Your Thyroid Health

The Thyroid Health - Comprehensive Lab panel further enhances the evaluation of thyroid health by adding two more thyroid specific tests, thyroxine binding globulin (TBG) and thyroid stimulating immunoglobulin (TSI).

Conditions Detected by the Thyroid Health - Advanced Lab Panel

The Advanced Lab panel can detect a wide range of thyroid disorders, including autoimmune thyroid diseases (Hashimoto's thyroiditis, Graves' disease), thyroid hormone imbalances, and conditions associated with elevated reverse T3 levels, which may indicate metabolic issues.

Utilization of Thyroid Health - Advanced Lab Panel Results by Healthcare Professionals

Healthcare professionals use the results of the Advanced Lab panel to diagnose, monitor, and manage complex thyroid disorders. Abnormal findings may lead to further evaluations, including imaging studies, medication adjustments, or referrals to endocrinologists. This panel provides valuable insights into the autoimmune aspects of thyroid diseases and reverse T3 levels, aiding in personalized treatment plans.

The Thyroid Health - Advanced Lab panel offers a comprehensive assessment of thyroid function, including autoimmune aspects, reverse T3 levels, and thyroid antibodies. It plays a pivotal role in diagnosing and managing complex thyroid disorders, providing healthcare professionals with the information needed to tailor treatment plans and improve the overall thyroid health of patients.

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results

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