Kidney Disease

Do you know which of the five kidney stages of health you're in?

Order your kidney function test from Ulta Lab Tests to know your kidney health and numbers, including your ACR (Albumin to Creatinine Ratio) and GFR (glomerular filtration rate). The GFR measures your kidney function and can identify if you have kidney disease and if the condition is present at which stage. Ulta Lab Tests provides reliable blood work and secure testing, so order today!

If you're experiencing any of the following symptoms, swelling in your feet and ankles, fatigue, nausea, vomiting, changes in urination frequency or color (darker urine), loss of appetite, weight loss, and weakness, it's time to test the health of your kidneys. You should also consider getting tested if you have a family history of kidney disease or diabetes. You may have kidney disease or a related condition that can affect how well your kidneys are working.

If you have diabetes or high blood pressure, it's especially important that you understand the five stages of kidney disease so that these conditions don't get worse over time.

Kidney disease is the 8th leading cause of death in the United States, and it affects more than 26 million Americans. We offer a wide range of lab tests for kidney function and related conditions that will provide you with the information you need to detect and monitor your kidney's health.

If you want to learn more about kidney disease and the lab tests that can help you, click on the title of the articles below.

If left untreated, chronic kidney disease can lead to heart failure and even death, so don't wait another day! Get tested today and gain peace of mind about your kidneys. Don't wait until it's too late – get tested today!

We offer a variety of kidney lab tests for early detection, including the BUN Blood Test, Creatinine Blood Test, and Urine Protein-to-Creatinine Ratio Test. These tests will help determine if there is an issue with your kidneys so you can get treatment before it becomes worse.

The phlebotomist who collects your samples are highly trained professionals who will ensure accuracy every step of the way, and our partner Quest Diagnostics will provide accurate results back to you quickly and efficiently through the Ulta Lab Tests platform. And because we know this is important information for you to have as soon as possible, test results are available within 24 -48 hours for most tests after they're collected!

Order your kidney lab tests from the selection below today and take charge of your health!

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This panel is designed for individuals diagnosed as having diabetes mellitus whose kidney disease has advanced to Stage 3/4 impairment. The panel affords the opportunity to assess electrolytes, phosphorus, serum creatinine/eGFR, hemoglobin, microalbumin, parathyroid hormone, calcium, and vitamin D. The grouping of these tests, readily identifiable as elements that adhere to guideline recommendations, is intended to facilitate the ready adherence to professional society clinical practice guidelines. Components of the testing related to the Management of CKD in diabetes, as outlined in the Standards of Medical Care in Diabetes 2013. These recommendations are in broad agreement with those published by the National Kidney Foundation and the American Association of Clinical Endocrinologists.

Comprehensive Metabolic Panel

See individual tests

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Serum creatinine is useful in the evaluation of kidney function and in monitoring renal dialysis. A serum creatinine result within the reference range does not rule out renal function impairment: serum creatinine is not sensitive to early renal damage since it varies with age, gender and ethnic background. The impact of these variables can be reduced by an estimation of the glomerular filtration rate using an equation that includes serum creatinine, age and gender.

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Creatinine Clearance is used to evaluate the glomerular filtration rate (GFR). Clearance is defined as that volume of plasma from which a measured amount of substance could be completely eliminated into the urine per unit of time. Daily creatinine production is fairly constant except when there is massive injury to muscle

Creatinine is the endproduct of creatine metabolism. Creatine is present primarily in muscle and the amount of creatinine produced is related to total skeletal muscle mass. Daily creatinine production is fairly constant except when there is massive injury to muscle. The kidneys excrete creatinine very efficiently and blood levels and daily urinary excretion of creatinine fluctuates very little in healthy normal people. Since blood and daily urine excretion of creatinine shows minimal fluctuation, creatinine excretion is useful in determining whether 24-hour urine specimens for other analytes (e.g., protein) have been completely and accurately collected

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Urea is the principle waste product of protein catabolism. BUN is most commonly measured in the diagnosis and treatment of certain renal and metabolic diseases. Increased BUN concentration may result from increased production of urea due to (1) diet or excessive destruction of cellular proteins as occurs in massive infection and fevers, (2) reduced renal perfusion resulting from dehydration or heart failure, (3) nearly all types of kidney disease, and (4) mechanical obstruction to urine excretion such as is caused by stones, tumors, infection, or stricture. Decreased urea levels are less frequent and occur primarily in advanced liver disease and in overhydration

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Dipstick urinalysis is important in accessing the chemical constituents in the urine and the relationship to various disease states. Microscopic examination helps to detect the presence of cells and other formed elements.

NOTE: Only measurable biomarkers will be reported.

Proteinuria is characteristic of renal disease and concentrations may be increased with diabetes, hypertension, nephritic syndrome, and drug nephrotoxicity.

Diabetic nephropathy is a complication of diabetes and is characterized by proteinuria. Before overt proteinuria develops, albumin excretion increases in those diabetic patients who are destined to develop diabetic nephropathy. There is a need to identify small, but abnormal, increases in the excretion of urinary albumin (in the range of 30-300 mg/day, ie, microalbuminuria). The National Kidney Foundation guidelines for the management of patients with diabetes and microalbuminuria recommend that all type 1 diabetic patients older than 12 years and all type 2 diabetic patients younger than 70 years have their urine tested for microalbuminuria yearly when they are under stable glucose control.

Microalbumin/Creatinine Ratio, Timed Urine 

Myasthenia Gravis (MG) is a neuromuscular disorder characterized by muscle weakness, most commonly due to autoantibody-mediated loss of functional acetylcholine receptors (AChR) in the neuromuscular junction. This assay aids in the differential diagnosis of MG-like muscle weakness, in differentiating between generalized MG and ocular MG, and in monitoring therapeutic response. If binding antibodies are negative, assays for blocking and modulating antibodies should be considered.

Myasthenia gravis (MG) is a neuromuscular disorder characterized by muscle weakness, most commonly due to autoantibody-mediated loss of functional acetylcholine receptors (AChR) in the neuromuscular junction. This assay is most useful when the acetylcholinesterase receptor modulating antibodies are positive. The assay for blocking antibodies is useful in monitoring response to therapy.

Myasthenia gravis (MG) is a neuromuscular disorder characterized by muscle weakness, most commonly due to autoantibody-mediated loss of functional acetylcholine receptors (AChR) in the neuromuscular junction. Modulating Antibody to AChR causes weakness by inhibiting or modulating binding to the receptors.

Actin is the major antigen to which smooth muscle antibodies react in autoimmune hepatitis. F-Actin IgG antibodies are found in 52-85% of patients with autoimmune hepatitis (AIH) or chronic active hepatitis and in 22% of patients with primary biliary cirrhosis (PBC). Anti-actin antibodies have been reported in 3-18% of sera from normal healthy controls.

Serum albumin measurements are used in the monitoring and treatment of numerous diseases involving those related to nutrition and pathology particularly in the liver and kidney. Serum albumin is valuable when following response to therapy where improvement in the serum albumin level is the best sign of successful medical treatment. There may be a loss of albumin in the gastrointestinal tract, in the urine secondary to renal damage or direct loss of albumin through the skin. More than 50% of patients with gluten enteropathy have depressed albumin. The only cause of increased albumin is dehydration; there is no naturally occurring hyperalbuminemia

Alpha 2 Macroglobulin

Antinuclear antibodies are associated with rheumatic diseases including Systemic Lupus Erythematous (SLE), mixed connective tissue disease, Sjogren's syndrome, scleroderma, polymyositis, CREST syndrome, and neurologic SLE. 

Reflex Information: If ANA Screen, IFA is positive, then ANA Titer and Pattern will be performed at an additional charge.


  • ANA Screen,IFA, with Reflex to Titer and Pattern
  • DNA (ds) Antibodies
  • Scleroderma Antibodies (SCL-70)
  • Sm and Sm/RNP Antibodies
  • Sjogren's Antibodies (SSA, SSB)

If ANA Screen, IFA is positive, then ANA Titer and Pattern will be performed at an additional charge - $13.00


Anion Gap Panel (Electrolyte Balance) includes the following test.

  • Anion gap 4
  • Sodium
  • Potassium
  • Chloride
  • Carbon dioxide

Beta-2-microglobulin normally passes through the glomerulus into the proximal tubule where much of it is reabsorbed. Serum levels are therefore an index of glomerular function. When impaired, serum levels rise in inverse ratio to glomerular filtration rate. Increased amounts of beta-2-microglobulin are excreted in several renal disorders, e.g., Balkan nephropathy, heavy metal poisoning and renal tubular disease due to therapeutic agents. Serial levels of beta-2-microglobulin in serum and urine are used to evaluate transplant viability and anticipate rejection. Following a successful graft, serum levels decline toward normal. Increasing serum levels provide an early sign of rejection. Elevated levels are also noted in lymphproliferative disorders, neoplasms (malignant and benign), inflammatory disease, and autoimmune diseases such as systemic lupus erythematosus (SLE) and Sjögren's disease

According to the National Center for Health Statistics survey, at least 6 million U.S. adults were diagnosed with kidney disease in 2018.

Your two kidneys are vital organs that perform essential roles in maintaining your health. Their primary functions include controlling water levels and essential minerals such as sodium for the body's optimum functioning.

Additionally, they help remove waste material from the blood; the kidneys are comprised of millions of nephrons, commonly referred to as blood-filtering units that filter waste such as urine from the blood.

The kidneys also help perform other miscellaneous roles, such as producing hormones that impact your overall body health.

What is Kidney Disease?

Kidney disease is a condition in which your kidneys are not functioning properly, leading to an abnormal concentration of waste products and chemical substances that may be life-threatening.

Therefore, it is advisable to ask your doctor about kidney disease screening. The sooner you get checked, the sooner you can seek treatment to protect your kidneys.

About Kidney Disease

A diagnosis of kidney disease is often defined by the gradual loss of kidney functions, such as filtration of waste from the blood and a high amount of protein in the urine.

Risk Factors for Kidney Disease

The main risk factors for kidney disease include the following:

  • Diabetes: uncontrolled diabetes leads to high blood glucose that gradually damages the kidneys' nephrons.
  • High blood pressure: it can cause damage to kidneys' blood vessels
  • Age: Older people above 60 are at a higher risk to develop kidney disease
  • Family history of inherited disorders such as polycystic kidney disease (PKD).

Causes of Kidney Disease

Different conditions can lead to a loss in kidney function. The leading causes include the following:

  • Decrease in blood flow to the kidneys
  • Drainage blockage from the kidney that is caused by enlarged prostate and kidney stones
  • Diabetes
  • Family history of inherited diseases such as polycystic kidney disease (PKD)
  • High blood pressure
  • Damage to kidney's filtering units (glomerulonephritis).

Signs and Symptoms of Kidney Disease?

Most people with kidney disease do not exhibit visible symptoms until their kidneys are badly damaged. The disease progresses silently without significant signs to suspect problems related to loss of kidney functions. However, lab tests during routine health examination can help detect early signs such as:

  • Hematuria (traces of blood in urine sample)
  • Proteinuria (proteins in the urine sample)
  • Decreased eGFR
  • Elevated creatinine
  • A decrease in the amount of urine
  • Urination problems such as burning sensation and abnormal discharge.

You may also notice the following symptoms in chronic kidney disease:

  • Muscle cramps
  • Darkened skin
  • Numbness in feet
  • Tiredness
  • Signs such as swollen legs and ankles that depict fluid retention.

Lab Tests for Kidney Disease

Doctors use different tests to check for kidney disease. They check your kidney numbers using the GFR (glomerular filtration rate) or ACR (Albumin to Creatinine Ratio) tests.

You may need the following lab tests and procedures for kidney disease diagnosis:

Blood Tests for Kidney Disease Testing

Most kidney function tests involve blood tests. Your doctor will check how well your kidney filters waste from your blood. The doctor will check the following:

Serum Creatinine Test

One sign of early kidney disease progression is the presence of creatinine in the blood. When your kidney muscles wear and tear, they produce creatinine as a waste product.

Creatinine level above 1.2 and 1.4 in women and men respectively shows that your kidney is not functioning correctly. However, these levels may vary depending on body size and age.

Blood Urea Nitrogen (BUN) Test

When you eat protein, your body breaks it down, and urea nitrogen is one of its waste products. A doctor will measure the level of urea nitrogen in your blood to check the level of your kidney function.

Often, the expected level should be between 7 and 20. An increase in its levels in the blood depicts a decrease in kidney function.

Blood Test to Estimate Glomerular Filtration Rate (GFR)

One of a healthy kidney's indicators is its ability to filter waste and excess fluid from your blood. Doctors use the estimated glomerular filtration rate to test for creatinine levels in your blood. Your GFR number helps doctors to determine the stage of your kidney disease.

The standard GFR value should be above 60. Your kidneys are not working properly if it drops below 60. Moreover, you are at a higher risk for kidney failure once your GFR drops to below 15.

Urine Tests

Doctors can determine the level of protein leaks from your kidney by conducting a urine test. A standard urine test includes the following:

A Urinalysis

Doctors conduct a microscopic examination to check for abnormalities such as the presence of excess proteins, blood, pus, and sugar in your urine sample. A urinalysis is effective in detecting chronic kidney disease and kidney stones.

A Urine protein test

This test confirms proteinuria, an excess amount of proteins in your urine.

Microalbumin (Checking Albumin in Urine)

The doctor uses this urine test to check a protein called albumin in your urine sample. Microalbumin testing encompasses using a sensitive dipstick test mostly for people at high risk of developing kidney disease.

A Test For Creatinine Clearance

Creatinine clearance test compares the level of creatinine in your urine sample. The doctor uses a 24-hours urine sample to determine how much waste the kidney filter out.

Imaging Tests

A doctor can order a kidney ultrasound to assess its structure or size.

Kidney Biopsy

A small sample of your kidney tissue may be examined for signs of damage. Doctors administer local anesthesia when performing a kidney biopsy.

Frequently Asked Questions About Kidney Disease and Lab Testing for Kidney Disease

Some fundamental questions about chronic kidney disease and kidney lab testing that you may ask your doctor include the following:

  • What is causing damage to my kidneys?
  • Is the level of damage to my kidney worsening?
  • Do I need a further lab test?
  • When can I see a kidney screening specialist?
  • How frequently should I have my kidney function tested in a year?
  • How can I manage kidney disease together with another health condition?
  • Should I consult a dietician to help me plan a special diet?

Get To Know Your Kidney Health: Order Your Kidney Disease Tests at Ulta Lab Tests Today!

Order your kidney lab tests at Ulta Lab Tests and enjoy the following benefits:

  • At Ulta Lab Tests, we offer tests that are highly accurate and reliable so that you can use them to make informed decisions about your health.
  • We send you secure and confidential results online.
  • You do not need insurance or a doctor’s referral to order kidney lab tests
  • You get affordable pricing that includes a doctor's order
  • We guarantee you 100% satisfaction.

Order your kidney lab tests and your results will be sent securely and confidentially online in 24 to 48 hours for most tests. Take charge of your kidney health and track your progress with Ulta Lab Tests today!