Chronic Inflammation

Chronic inflammation can lead to serious health conditions such as heart disease and cancer.

That's why regular blood tests to detect inflammation are important for optimal health. The chronic inflammation test measures the level of c-reactive protein (CRP) in your blood that is sent into your bloodstream in response to inflammation if you've been injured or have an infection. 

Inflammation is the root cause of many chronic diseases. It can be difficult to detect, but it's important that you are aware of your health and keep track of any changes in your body. That's why we offer blood tests that measure inflammation levels so you can stay healthy for years to come.

There may be no observable signs or symptoms of persistent inflammation. However, lab testing can reveal otherwise undetectable indicators of chronic inflammation. 

Chronic inflammation occurs when your body sustains a low-grade immune response in reaction to an internal or external stressor. Immune tolerance can be compromised by chronic inflammation. Your body's capacity to perceive some drugs as safe and non-threatening is known as immune tolerance. When your immunological tolerance is harmed, your body may mistakenly see harmless things or objects, such as healthy cells, as dangers and attack them. 

Another impact of persistent inflammation is a weakened immune system, which is unable to respond appropriately to threats such as viruses and bacteria. Vaccines are less effective when the immune system is weak because they are designed to elicit an immunological response.

If you want to learn more about inflammation and the lab tests that can help you, click on the title of the articles below.

Because of their subtlety, the signs and symptoms of chronic inflammation are often overlooked. If persistent inflammation has played a role in the development of a disease such as osteoporosis or cardiovascular disease, a person may have symptoms associated with the disease's progression. 

Our blood test will give you a clear picture of how your body is doing by measuring C-reactive protein (CRP) levels in just one simple test. This marker shows how much inflammation there is in the body, which could lead to heart disease or diabetes if left untreated over time. If CRP levels are high, it means there may be an underlying problem with your health that needs attention right away! 

Ulta Lab Tests provides an affordable and convenient way for you to take charge of your health! Order your discounted lab tests online 24/7, and take advantage of our 2100 nationwide locations. With 30-minute in-and-out local testing, low prices guaranteed, and confidential results, Ulta Lab Tests is the perfect solution for anyone looking to get reliable lab test results quickly and easily. Plus, our dynamic charting feature allows you to track changes in your results over time. So why wait? Order your lab tests today!

Order your blood tests for inflammation from the selection below today and take charge of your health!

Name Matches

  • ANA Screen, IFA with Reflex to Titer and Pattern, IFA
  • Creatine Kinase (CK), Total
  • Homocysteine
  • hs-CRP
  • Sed Rate by Modified Westergren (ESR)
  • Uric Acid

ANA Screen, IFA with Reflex to Titer and Pattern, IFA
Bilirubin, Direct
CBC (includes Differential and Platelets)
Comprehensive Metabolic Panel (CMP)
Creatine Kinase (CK), Total
Gamma Glutamyl Transferase (GGT)
Gliadin (Deamidated Peptide) Antibody (IgA)
Gliadin (Deamidated Peptide) Antibody (IgG)
Hemoglobin A1c (HgbA1C)
Immunofixation (IFE), Serum
Indican, Urine
Lactate Dehydrogenase (LD)
Lipid Panel with Ratios
Omega-3 and -6 Fatty Acids, Plasma
Phosphate (as Phosphorus)
QuestAssureD™ 25-Hydroxyvitamin D (D2, D3), LC/MS/MS
Rheumatoid Factor
Thyroid Peroxidase Antibodies (TPO)
Uric Acid
Urinalysis (UA), Complete

  • ANA Screen, IFA with Reflex to Titer and Pattern, IFA
  • Creatine Kinase (CK), Total
  • Homocysteine
  • hs-CRP
  • Sed Rate by Modified Westergren (ESR)
  • Thyroid Peroxidase Antibodies (TPO)
  • Uric Acid

Ulta - Arthritis & Inflammation Deep Dive

This panel is a cure for WYSIATI – what-you-see-is-all-there-is. If all we do is measure a simple inflammation test, like the CRP, it is easy to fall into a trap of assuming inflammation is “arthritis”. But what if there is an infection or what if there is another reason for the pain or inflammation-like symptoms? Could it be a nutrient deficiency or excess? Could it be lack of recovery or abnormal stress hormone? This panel offers a remarkably deep dig into possible causes of inflammation, well beyond the typical tests ordered in practice. Sometimes our first impression is not the true answer. Results should be reviewed with you by a licensed healthcare provider.

  • ANA Screen, IFA with Reflex to Titer and Pattern, IFA #249
  • C-Reactive Protein (CRP) #4420
  • CBC (includes Differential and Platelets) #6399
  • Comprehensive Metabolic Panel (CMP) #10231
  • Cyclic Citrullinated Peptide (CCP) Antibody (IgG) #11173
  • Lipid Panel with Ratios #19543
  • Rheumatoid Factor #4418
  • Sed Rate by Modified Westergren (ESR) #809
  • Lyme Disease Antibodies (IgG, IgM), Immunoblot #8593
  • Cortisol, A.M. #4212
  • Creatine Kinase (CK), Total #374
  • DHEA Sulfate, Immunoassay #402
  • Ferritin #457
  • Hemoglobin A1c (HgbA1C) #496
  • Insulin #561
  • Testosterone, Free (Dialysis) and Total MS #36170
  • TSH #899
  • Vitamin B12 (Cobalamin) #927
  • Vitamin D, 25-Hydroxy, Total, Immunoassay #17306

DC - Comprehensive Inflammation Panel

OOL - Extensive Inflammation Panel

OOL - Extensive Inflammation Panel - without Sed Rate by Modified Westergren (ESR)

Increased CRP levels are found in inflammatory conditions including: bacterial infection, rheumatic fever, active arthritis, myocardial infarction, malignancies and in the post-operative state. This test cannot detect the relatively small elevations of CRP that are associated with increased cardiovascular risk.

C-Reactive Protein Cardiac (hs CRP) Useful in predicting risk for cardiovascular disease.

Useful in differentiating inflammatory and neoplastic diseases and as an index of disease severity. CRP is also useful in monitoring inflammatory disease states.

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Elevated levels of homocysteine are observed in patients at risk for coronary heart disease and stroke.

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Serum uric acid measurements are useful in the diagnosis and treatment of numerous renal and metabolic disorders, including renal failure, gout, leukemia, psoriasis, starvation or other wasting conditions, and in patients receiving cytotoxic drugs.

A lipid panel includes:Total cholesterol —this test measures all of the cholesterol in all the lipoprotein particles.High-density lipoprotein cholesterol (HDL-C) — measures the cholesterol in HDL particles; often called "good cholesterol" because it removes excess cholesterol and carries it to the liver for removal.Low-density lipoprotein cholesterol (LDL-C) — calculates the cholesterol in LDL particles; often called "bad cholesterol" because it deposits excess cholesterol in walls of blood vessels, which can contribute to atherosclerosis. Usually, the amount of LDL cholesterol (LDL-C) is calculated using the results of total cholesterol, HDL-C, and triglycerides.Triglycerides — measures all the triglycerides in all the lipoprotein particles; most is in the very low-density lipoproteins (VLDL).Very low-density lipoprotein cholesterol (VLDL-C) — calculated from triglycerides/5; this formula is based on the typical composition of VLDL particles.Non-HDL-C — calculated from total cholesterol minus HDL-C.Cholesterol/HDL ratio — calculated ratio of total cholesterol to HDL-C.

Serum iron quantification is useful in confirming the diagnosis of iron-deficiency anemia or hemochromatosis. The measurement of total iron binding in the same specimen may facilitate the clinician''s ability to distinguish between low serum iron levels caused by iron deficiency from those related to inflammatory neoplastic disorders. The assay for iron measures the amount of iron which is bound to transferrin. The total iron binding capacity (TIBC) measures the amount of iron that would appear in blood if all the transferrin were saturated with iron. It is an indirect measurement of transferri

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Aids in the diagnosis of primary disease of skeletal muscle myocardial infarction and viral hepatitis.

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The major sources of amylase are the pancreas and the salivary glands. The most common cause of elevation of serum amylase is inflammation of the pancreas (pancreatitis). In acute pancreatitis, serum amylase begins to rise within 6-24 hours, remains elevated for a few days and returns to normal in 3-7 days. Other causes of elevated serum amylase are inflammation of salivary glands (mumps), biliary tract disease and bowel obstruction. Elevated serum amylase can also be seen with drugs (e.g., morphine) which constrict the pancreatic duct sphincter preventing excretion of amylase into the intestine.

Antinuclear antibodies are associated with rheumatic diseases including Systemic Lupus Erythematous (SLE), mixed connective tissue disease, Sjogren's syndrome, scleroderma, polymyositis, CREST syndrome, and neurologic SLE. 

Reflex Information: If ANA Screen, IFA is positive, then ANA Titer and Pattern will be performed at an additional charge.

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Measurement of the levels of bilirubin is used in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gall bladder obstruction. The assessment of direct bilirubin is helpful in the differentiation of hepatic disorders. The increase in total bilirubin associated with obstructive jaundice is primarily due to the direct (conjugated) fraction. Both direct and indirect bilirubin are increased in the serum with hepatitis.

Clinical Significance

Used to diagnose inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, or to differentiate IBD from irritable bowel syndrome (IBS).


Collection Instructions

Collect undiluted feces in clean, dry sterile leak-proof container. Do not add fixative or preservative.


Low levels of fibrinogen are associated with bleeding most commonly secondary to liver disease or disseminated intravascular coagulation (DIC). Fibrinogen is an acute phase reactant and thus elevated levels may be associated with inflammation. Increased concentrations are also associated with increased risk of atherosclerosis.

A Complete Blood Count (CBC) Panel is used as a screening test for various disease states including anemia, leukemia, and inflammatory processes.

A CBC blood test includes the following biomarkers: WBC, RBC, Hemoglobin, Hematocrit, MCV, MCH, MCHC, RDW, Platelet count, Neutrophils, Lymphs, Monocytes, Eos, Basos, Neutrophils (Absolute), Lymphs (Absolute), Monocytes(Absolute), Eos (Absolute), Basos (Absolute), Immature Granulocytes, Immature Grans (Abs)

NOTE: Only measurable biomarkers will be reported.

Reflex Parameters for Manual Slide Review
  Less than  Greater Than 
WBC  1.5 x 10^3  30.0 x 10^3 
Hemoglobin  7.0 g/dL  19.0 g/dL 
Hematocrit  None  75%
Platelet  100 x 10^3  800 x 10^3 
MCV  70 fL  115 fL 
MCH  22 pg  37 pg 
MCHC  29 g/dL  36.5 g/dL 
RBC  None  8.00 x 10^6 
RDW  None  21.5
Relative Neutrophil %  1% or ABNC <500  None 
Relative Lymphocyte %  1% 70%
Relative Monocyte %  None  25%
Eosinophil  None  35%
Basophil  None  3.50%
Platelet  <75 with no flags,
>100 and <130 with platelet clump flag present,
Instrument Flags Variant lymphs, blasts,
immature neutrophils,  nRBC’s, abnormal platelets,
giant platelets, potential interference
The automated differential averages 6000+ cells. If none of the above parameters are met, the results are released without manual review.
CBC Reflex Pathway

Step 1 - The slide review is performed by qualified Laboratory staff and includes:

  • Confirmation of differential percentages
  • WBC and platelet estimates, when needed
  • Full review of RBC morphology
  • Comments for toxic changes, RBC inclusions, abnormal lymphs, and other
  • significant findings
  • If the differential percentages agree with the automated counts and no abnormal cells are seen, the automated differential is reported with appropriate comments

Step 2 - The slide review is performed by qualified Laboratory staff and includes: If any of the following are seen on the slide review, Laboratory staff will perform a manual differential:

  • Immature, abnormal, or toxic cells
  • nRBC’s
  • Disagreement with automated differential
  • Atypical/abnormal RBC morphology
  • Any RBC inclusions

Step 3 If any of the following are seen on the manual differential, a Pathologist will review the slide:

  • WBC<1,500 with abnormal cells noted
  • Blasts/immature cells, hairy cell lymphs, or megakaryocytes
  • New abnormal lymphocytes or monocytes
  • Variant or atypical lymphs >15%
  • Blood parasites
  • RBC morphology with 3+ spherocytes, RBC inclusions, suspect Hgb-C,
  • crystals, Pappenheimer bodies or bizarre morphology
  • nRBC’s

Inflammation is typically a normal part of the healing process. The process of inflammation activates your immune system and helps your body rid itself of toxins or pathogens that pose a threat. It can also prompt your body to repair damaged tissues. Acute inflammation is easily recognizable because of the short-term effects, but chronic inflammation often occurs at a low, consistent level that makes it almost undetectable without testing.

About Chronic Inflammation

Chronic inflammation occurs when your body continually reacts to some internal or external stressor by maintaining a low-grade immune response. Chronic inflammation can cause a breakdown in immune tolerance. Immune tolerance is your body’s ability to recognize certain substances as safe and non-threatening. Damaging your immune tolerance can cause your body to treat safe substances or objects like healthy cells as threats and attack them needlessly. 

Another side effect of chronic inflammation is an impaired immune system that can’t respond adequately to threats like viruses and bacteria. Since vaccines are meant to trigger an immune response, a weak immune system makes vaccinations less effective.

Risk Factors and Causes of Chronic Inflammation


To a certain extent, aging is an almost unavoidable risk factor for chronic inflammation. Cell senescence, the permanent end of a cell’s growth and ability to reproduce that occurs as people age, triggers the production of certain proteins linked to inflammation. However, there are also many lifestyle factors that put people at risk of developing chronic inflammation.


Research shows that diseases related to chronic inflammation, such as cardiovascular disease, cancer, and diabetes, are more common in Westernized countries than those that have more unprocessed and raw diets. Inflammatory diets that include large amounts of red meat, processed food, refined sugars, and high fructose corn syrup put individuals at risk of increased inflammation. 

A Sedentary Lifestyle

A processed, refined diet is one risk factor and cause of inflammation, but a lack of physical activity is also a cause. One small study found that people that were physically active had a lower circulation of inflammatory proteins and cholesterol than inactive people. 

Environmental Factors

In some cases, environmental factors can cause chronic inflammation. Toxic chemicals can irritate and cause inflammation in certain parts of the body, like the throat or skin. Smoking is a known risk factor for inflammation, but consistent exposure to secondhand smoke can also have a similar effect.

Oxidative Stress

Physical inactivity and a poor diet can put oxidative stress on your body. Oxidative stress is defined as an imbalance of oxidants and antioxidants in the body. Some oxidants that interact harmfully with other molecules and cause cell death and damaged proteins are called reactive oxygen species. Oxidants are normally released during acute inflammation, but chronic inflammation causes a buildup of these molecules that the body can’t adequately eliminate. A diet that’s low in antioxidants means a person can’t fight oxidative stress. 

Signs and Symptoms of Chronic Inflammation

The signs and symptoms of chronic inflammation are often almost unnoticeable because of their subtlety. If a person’s chronic inflammation has contributed to a disease like osteoporosis or cardiovascular disease, they may notice symptoms related to that disease and its progression.

Someone with chronic inflammation might have no visible symptoms. With lab testing, however, you can find invisible signs of chronic inflammation.

Lab Tests for Chronic Inflammation

Lab tests for chronic inflammation measure your blood's levels of certain inflammation markers by running your sample through a series of tests. One of these is an erythrocyte sedimentation rate or sed rate test. This test can indirectly determine your body’s current inflammatory response to stressors like a disease.

One sign of inflammation may be raised levels of C-reactive protein (CRP). The C-Reactive protein (CRP) test measures the amount of this protein, which is made by the liver. An increase in CRP levels in a person's bloodstream can indicate a condition that causes inflammation. A CRP test can detect inflammation caused by acute conditions and can help monitor the severity of disease in chronic conditions.

Chronic inflammation tests might also test for lipids like cholesterol, iron, and uric acid. These tests are the best way to determine your body’s inflammation. 


How Can You Tell If You Have Chronic Inflammation?

The best way to tell if you have chronic inflammation is through a test. Symptoms can be undetectable and you may not feel any different. If you have inflammatory conditions related to chronic inflammation, like Crohn's Disease or ulcerative colitis, the symptoms of this disease are signs of inflammation.

How Do You Stop Chronic Inflammation?

Adopting a healthy lifestyle can reduce chronic inflammation. Increasing your physical activity and adopting a diet similar to the ones found in the Mediterranean region are two ways to support the anti-inflammatory process. Eating foods rich in antioxidants can help fend off oxidative stress, which can be a cause of inflammation.

Is There A Test for Chronic Inflammation?

Yes, Ulta Lab Tests offers tests for chronic inflammation that examine a number of substances in the blood, including gamma-glutamyl transferase (GGT)lipidsiron and C-reactive protein. Our chronic inflammation test also includes antinuclear antibodyCBCSED ratecomprehensive metabolic panel and rheumatoid factor tests.  

Benefits of Chronic Inflammation Testing with Ulta Lab Tests

Ulta Lab Tests offers highly accurate and reliable tests so you can make informed decisions about your health.

  • Secure and confidential results
  • No insurance or doctor's referral is needed
  • Affordable pricing
  • 100% satisfaction guarantee

Our chronic inflammation tests can help you determine your risk factor for illnesses associated with inflammation and give you another tool to stop the progression of inflammation before it becomes severe. Order your chronic inflammation lab tests today, and your results will be provided to you securely and confidentially online in 24 to 48 hours for most tests.

Take control of your health today with Ulta Lab Tests.