Inflammation Lab Panel

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: ANA, ANA Screen IFA with Reflex to Titer and Pattern IFA, ANA with Reflux

ANA Screen, IFA

The antinuclear antibody (ANA) test is ordered to help screen for autoimmune disorders and is most often used as one of the tests to diagnose systemic lupus erythematosus (SLE).

Also known as: C-Reactive Protein, CReactive Protein CRP, CRP

C-REACTIVE PROTEIN

C-reactive protein is produced by the liver. The level of CRP rises when there is inflammation throughout the body.

Also known as: CK (Total), CPK, CPK (Total), Creatine Kinase CK Total, Creatine Phosphokinase (CPK), Total CK

Creatine Kinase, Total

Also known as: Homocysteine, Homocysteine Cardiovascular

HOMOCYSTEINE,

Also known as: ESR, SED RATE, Sed Rate by Modified Westergren ESR

Sed Rate By Modified

Erythrocyte sedimentation rate (ESR) is an indirect measure of the degree of inflammation present in the body. It actually measures the rate of fall (sedimentation) of erythrocytes (red blood cells) in a sample of blood.

Also known as: Serum Urate, UA

Uric Acid

Uric acid is a chemical created when the body breaks down substances called purines. Purines are found in some foods and drinks. These include liver, anchovies, mackerel, dried beans and peas, and beer. Most uric acid dissolves in blood and travels to the kidneys. From there, it passes out in urine. If your body produces too much uric acid or doesn't remove enough if it, you can get sick. A high level of uric acid in the blood is called hyperuricemia.
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The Inflammation Lab Panel panel contains 6 tests with 6 biomarkers.

Brief Description: The Inflammation Lab Panel is a comprehensive diagnostic tool designed to assess various biomarkers related to inflammation within the body. This panel helps to identify underlying causes of inflammation, monitor the status of inflammatory diseases, and guide the treatment of various autoimmune, infectious, and metabolic conditions. By evaluating a combination of specific tests, this panel provides valuable insights into the overall inflammatory state, helping healthcare providers develop effective management strategies for their patients.

Important: This panel contains ANA Screen IFA with Reflex to Titer and Pattern #249 which is a Reflex test. If ANA Screen, IFA is positive, then ANA Titer and Pattern will be performed at an additional

Collection Method: Blood Draw

Specimen Type: Serum

Test Preparation: No preparation required

When and Why the Inflammation Lab Panel May Be Ordered

The Inflammation Lab Panel is typically ordered when a patient presents symptoms suggestive of an inflammatory or autoimmune disorder, such as joint pain, fatigue, fever, and unexplained weight loss. It is also used to monitor disease progression or response to treatment in patients with known inflammatory conditions. This panel is crucial for diagnosing diseases where inflammation plays a key role and ensuring that appropriate therapeutic measures are taken to address these complex disorders.

What the Inflammation Lab Panel Checks For

Each test within the panel provides specific information about different aspects of the body's inflammatory response:

  • ANA Screen IFA with Reflex to Titer and Pattern IFA: This test detects antinuclear antibodies, which are often present in individuals with autoimmune disorders. A positive ANA test can lead to further testing to determine the specific pattern and titer, helping to pinpoint the type of autoimmune disease.

  • C-Reactive Protein (CRP): CRP is a protein that increases in the blood with inflammation and infections. Elevated CRP levels can indicate acute inflammation or chronic diseases.

  • Creatine Kinase Total: This enzyme is found in the heart, brain, skeletal muscle, and other tissues. High levels can indicate muscle damage, which can be due to various causes, including muscular diseases, physical injury, or chronic inflammation.

  • Homocysteine: Elevated homocysteine levels can suggest a risk of cardiovascular diseases and are also associated with vitamin B12 deficiency, which can lead to inflammatory conditions.

  • Sed Rate (ESR): The sedimentation rate is a test that measures how quickly red blood cells settle in a test tube in one hour. It is used to detect inflammation associated with conditions such as infections, cancers, and autoimmune diseases.

  • Uric Acid: Uric acid is produced from the natural breakdown of your body's cells and from the foods you eat. High levels can lead to gout, a form of arthritis that causes severe pain and swelling.

Conditions and Diseases Detected by the Inflammation Lab Panel

This panel is instrumental in diagnosing and managing conditions such as:

  • Autoimmune Disorders: Conditions like lupus, rheumatoid arthritis, and scleroderma can be suggested by a positive ANA test and supported by abnormal CRP and ESR levels.

  • Inflammatory Diseases: Chronic inflammatory states such as Crohn’s disease, ulcerative colitis, and temporal arteritis are typically associated with high CRP and ESR levels.

  • Muscle Inflammation and Damage: Elevated creatine kinase levels can diagnose conditions like polymyositis or muscular dystrophy.

  • Gout and Kidney Stones: High uric acid levels are crucial for diagnosing gout and can also indicate kidney stones or kidney damage.

Using the Results of the Inflammation Lab Panel

Healthcare professionals use the results from this panel to:

  • Diagnose Inflammatory and Autoimmune Diseases: Identifying specific patterns in the test results can help pinpoint the type of inflammation and its possible causes.

  • Guide Treatment Decisions: Depending on the identified condition, treatments may include anti-inflammatory medications, immune-suppressing drugs, or lifestyle changes.

  • Monitor Disease Progression and Response to Treatment: Regularly repeating the panel can determine if the condition is improving or worsening and if treatments are effective.

The Inflammation Lab Panel is a vital tool in the diagnosis and management of various diseases where inflammation is a key underlying factor. By providing a detailed profile of inflammatory markers, this panel allows for targeted treatment strategies that can significantly improve patient outcomes. It underscores the importance of a comprehensive approach in understanding and managing inflammatory conditions.

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.

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