All Digestive System Tests

“All Digestive System Tests” brings your core GI lab options into one place. A proactive plan starts by matching your question—infection, inflammation, bleeding, malabsorption, reflux/dyspepsia, or pancreatic issues—to the right stool, breath, and blood tests. Noninvasive stool markers (calprotectin/lactoferrin) help separate inflammatory bowel disease (IBD) from non-inflammatory causes like IBS. Pathogen PCR and C. difficile testing identify infections fast. For upper-GI concerns, H. pylori stool antigen or urea breath tests evaluate ulcer risk. Chronic diarrhea, weight loss, or greasy stools point to malabsorption tests (fecal fat, pancreatic elastase) and nutrient panels.

Blood work—CBC, CMP/electrolytes, CRP/ESR, iron/ferritin, B12/folate, vitamin D, liver enzymes—adds context on hydration, anemia, inflammation, and organ status. Labs guide next steps and monitoring but do not replace a clinician’s exam, imaging, or endoscopy when indicated.

Signs, Symptoms & Related Situations

  • Digestive: abdominal pain/cramping, bloating, early fullness, nausea/vomiting, diarrhea or constipation, mucus or blood in stool

  • Systemic: fever, fatigue, unintended weight loss, night sweats

  • Malabsorption: greasy/floating stools, weight loss, low iron/B12/folate/vitamin D

  • Risk clues: recent antibiotics or hospitalization (C. difficile), travel/unsafe food, NSAID use, autoimmune disease, family history of IBD/celiac/colon cancer

  • Urgent care: severe rectal bleeding, black/tarry stools, persistent high fever with dehydration, severe abdominal pain, fainting
    All symptoms should be evaluated by a qualified clinician.

Why These Tests Matter

What testing can do

  • Differentiate inflammation vs. functional disorders (e.g., IBD vs. IBS)

  • Detect infectious causes rapidly to guide care and reduce spread

  • Identify bleeding and malabsorption with objective markers

  • Establish baselines and trend results to time escalation (e.g., endoscopy)

What testing cannot do

  • Replace colonoscopy or upper endoscopy when visualization/biopsy is needed

  • Diagnose the exact cause of pain without clinical context

  • Serve as broad screening when symptoms are absent—use tests that fit the clinical question

What These Tests Measure (at a glance)

  • Inflammation (stool): Fecal calprotectin / lactoferrin—neutrophil proteins that rise with intestinal inflammation (IBD signal). Caveat: infection/NSAIDs can elevate; trends matter.*

  • Infection (stool): GI pathogen PCR panel (bacteria/viruses/parasites); C. difficile toxin/PCR for antibiotic-associated diarrhea. Caveat: test only unformed stools for C. diff; colonization occurs.*

  • Bleeding/screening (stool): FIT (fecal immunochemical test) and stool DNA–FITpositive → diagnostic colonoscopyCaveat: FIT preferred over guaiac occult blood.*

  • Ulcer/H. pylori: Stool antigen or urea breath test for active infection. Caveat: follow PPI/antibiotic/bismuth medication holds for accuracy.*

  • Celiac disease (blood ± stool context): tTG-IgA + total IgA (reflex to IgG tests if IgA deficient); consider EMAfor specificity. Caveat: must be on a gluten-containing diet.*

  • Malabsorption/EPI: Fecal elastase-1 (exocrine pancreatic insufficiency), fecal fat (steatorrhea). Caveat: watery stools can dilute elastase; repeat if borderline.*

  • Pancreas acute context (blood): Lipase (± amylase) for pancreatitis; triglyceridescalcium, and liver panel for causes/complications.

  • Breath tests (selected): Hydrogen/methane lactose breath (lactose malabsorption); lactulose breath (SIBO, clinician-directed). Caveat: prep affects results.*

  • Blood context labs: CBC, CMP/electrolytes, CRP/ESR, iron/ferritin, B12/folate, vitamin D, liver enzymes (ALT/AST/ALP/bilirubin)—anemia, hydration, inflammation, organ status.

How the Testing Process Works

  1. Define the question: infection, inflammation, bleeding, malabsorption, reflux/ulcer, or pancreas.

  2. Select tests: choose stool/serology/breath aligned to the question; add CBC/CMP/CRP-ESR for context.

  3. Collect correctly: follow stool kit and breath-test prep (avoid contamination; observe diet/med holds).

  4. View results securely: most stool/blood tests post within a few days.

  5. Plan next steps: your clinician may recommend therapy, dietary changes, colonoscopy/endoscopy, or imaging based on combined findings.

Interpreting Results (General Guidance)

  • High fecal calprotectin/lactoferrin: supports organic inflammation (e.g., IBD) over IBS; consider repeat testing or endoscopy.

  • Positive pathogen or C. difficile: indicates infection; correlate with symptoms before escalating care.

  • Positive FIT or stool DNA–FIT: requires diagnostic colonoscopy—do not rely on repeat stool testing.

  • Positive H. pylori stool antigen/UBT: supports active infection in the right setting; follow test-of-cure timing after therapy.

  • Low fecal elastase-1 or abnormal nutrition labs: suggests malabsorption/EPI; recheck after treatment.
    Always interpret results with a qualified healthcare professional.

Choosing Panels vs. Individual Tests

  • Inflammation vs. IBS: Fecal calprotectin (± lactoferrin) + CRP/ESR; add CBC/CMP.

  • Acute diarrhea: GI pathogen PCR; add C. difficile with recent antibiotics/hospitalization.

  • Ulcer symptoms/dyspepsia: H. pylori stool antigen or urea breath test (observe prep).

  • Chronic diarrhea/weight loss: Celiac panelfecal fat/pancreatic elastase, and nutrient labs.

  • Bleeding/screening question: FIT or stool DNA–FITpositive → colonoscopy.

  • Pancreatic pain: Lipase + CMP/liver panel ± triglycerides/calcium; add fecal elastase for chronic steatorrhea.

FAQs

Do stool tests replace colonoscopy?
No. Positive screens or alarm features typically require endoscopy for diagnosis and treatment.

How fast are GI pathogen PCR results?
Often 1–2 days; cultures and ova/parasite exams may take longer.

Can I test for H. pylori while on PPIs or antibiotics?
These can affect accuracy; follow the medication hold instructions on your order.

What distinguishes IBD from IBS in testing?
Fecal calprotectin/lactoferrin and CRP/ESR support IBD when elevated; IBS typically has normal inflammatory markers.

What tests check for malabsorption?
Fecal fatpancreatic elastase, and nutrient panels (iron, B12, folate, vitamin D) provide key clues.

When do I need breath tests?
Use lactose hydrogen/methane for suspected lactose malabsorption and lactulose for SIBO when clinically directed.

Internal Links & Cross-References

  • Digestive System Tests Hub

  • Digestive Health • Colon (Intestine) • Diarrhea • Celiac Disease • H. pylori • Pancreatic Diseases • Inflammatory Bowel Disease (IBD) • Lactose Intolerance

  • Key Lab Tests: Fecal Calprotectin • Fecal Lactoferrin • GI Pathogen PCR • C. difficile Toxin/PCR • FIT • Stool DNA–FIT • H. pylori Stool Antigen • Urea Breath Test • Fecal Fat • Pancreatic Elastase • CBC • CMP • CRP • ESR • Iron/Ferritin • Vitamin B12 • Folate • Vitamin D • Lipase • Liver Enzymes

References

  1. American Gastroenterological Association. Fecal Calprotectin/Lactoferrin in IBD—Technical Review.

  2. Infectious Diseases Society of America. Guidelines for Infectious Diarrhea and C. difficile.

  3. American College of Gastroenterology. H. pylori and Dyspepsia—Diagnosis and Management Guidelines.

  4. U.S. Preventive Services Task Force. Colorectal Cancer Screening—Stool-Based Options.

  5. National Institute of Diabetes and Digestive and Kidney Diseases. Digestive Diseases—Testing and Diagnosis.

  6. American College of Gastroenterology/AGA. Exocrine Pancreatic Insufficiency and Pancreatitis Guidance.

  7. American Society for Clinical Pathology. Appropriate Use of Stool Testing for GI Pathogens.

Available Tests & Panels

Your All Digestive System Tests menu is pre-populated in the Ulta Lab Tests system. Use filters to select inflammation markersinfection panelsH. pylori and celiac evaluations, malabsorption/pancreatic tests, and blood context labs. Review all results with your clinician and plan next steps based on combined findings.

Ulta Lab Tests provides panels of tests for conditions that contain the tests needed to detect and manage the following conditions.

At Ulta Lab Tests, we understand the importance of diagnosing and managing digestive conditions. We provide a comprehensive range of testing solutions to keep your digestive system in optimal health. 

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The Glucose Plasma Test measures the amount of glucose in the blood to assess how the body regulates sugar. Abnormal results may indicate diabetes, prediabetes, hypoglycemia, or other metabolic disorders. Doctors order this test for patients with symptoms like fatigue, excessive thirst, or frequent urination. It is also commonly used for routine health screening, monitoring diabetes treatment, and guiding lifestyle or medication adjustments.

Blood
Blood Draw
Also Known As: FPG Test, Fasting Plasma Glucose Test, Fasting Blood Sugar Test

The Glucose Random Test evaluates glucose levels in the blood without requiring fasting, making it useful for detecting abnormal sugar regulation. Elevated or low results may suggest diabetes, prediabetes, or hypoglycemia. This test supports assessment of metabolic function, carbohydrate processing, and systemic health, offering insight into symptoms like thirst, frequent urination, or unexplained fatigue.

Also Known As: Non-Fasting Glucose Test

Most Popular

The Glucose Test measures blood sugar levels to evaluate energy metabolism and screen for diabetes or prediabetes. Abnormal glucose may indicate hyperglycemia, hypoglycemia, or metabolic disorders. Doctors use this test during routine exams, to investigate symptoms like fatigue, excessive thirst, or frequent urination, and to monitor treatment for diabetes. It provides essential insight into how the body regulates blood sugar and overall metabolic health.

Blood
Blood Draw
Also Known As: Fasting Glucose Test, Fasting Blood Sugar Test

Blood
Blood Draw, Phlebotomist

Blood
Blood Draw, Phlebotomist

Blood
Blood Draw

The Haptoglobin Test measures levels of haptoglobin, a protein produced by the liver that binds free hemoglobin released from red blood cells. Low levels may indicate hemolytic anemia, liver disease, or red blood cell destruction, while elevated levels may occur with inflammation or tissue damage. Doctors use this blood test to help diagnose anemia causes, assess liver function, and monitor conditions affecting red blood cell health.

Blood
Blood Draw
Also Known As: HPT Test, Hemoglobin-binding Protein Test, Hp Test

The Heavy Metals 24-Hour Urine Test Panel with Cadmium measures excretion of toxic metals including lead, arsenic, mercury, and cadmium. Using a 24-hour urine collection, it helps assess acute or chronic exposure from environmental, dietary, or occupational sources. Elevated levels may be linked to kidney damage, neurological changes, or cardiovascular risk. Results support evaluation of toxic metal burden and exposure history.

Urine
Urine Collection

The Helicobacter pylori Antigen Stool Test detects H. pylori proteins in stool to diagnose active infection. H. pylori is a common cause of gastritis, ulcers, and increased stomach cancer risk. Doctors order this test for patients with abdominal pain, nausea, bloating, or indigestion. Noninvasive and accurate, results confirm active infection and are also used to monitor treatment effectiveness and eradication of H. pylori bacteria.

Stool
Stool Collection
Also Known As: H Pylori Stool Test

The Helicobacter pylori Urea Breath Test detects H. pylori infection, a common cause of ulcers and gastritis. After drinking a urea solution, breath samples are analyzed for carbon dioxide changes caused by the bacteria. A positive result indicates active infection, while a negative shows no evidence of H. pylori. Doctors use this noninvasive test to diagnose infection, confirm eradication after treatment, and monitor gastrointestinal health.

Varied
Phlebotomist
Also Known As: H Pylori Breath Test

The Hemoglobinopathy Evaluation screens for abnormal hemoglobin variants and thalassemias by analyzing the types and amounts of hemoglobin in blood. This test helps diagnose sickle cell disease, beta thalassemia, alpha thalassemia, and other inherited disorders affecting red blood cells. Doctors use it to investigate anemia, unexplained blood abnormalities, or family history of hemoglobinopathies, guiding diagnosis, genetic counseling, and treatment planning.

Also Known As: Hemoglobin Evaluation Test, Hb ELP Test, Hb IEF, Sickle Cell Screen Test, Hemoglobin Fraction Test, Hemoglobinopathies Test

The Hemogram and Differential Test provides a detailed analysis of blood health by measuring red blood cells, white blood cells, hemoglobin, hematocrit, and platelets. The differential count breaks down types of white blood cells, including neutrophils, lymphocytes, monocytes, eosinophils, and basophils. This test helps detect anemia, infections, immune response, clotting disorders, and other hematologic or systemic conditions.

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Blood Draw

The Hemogram Test provides a detailed blood profile including WBC, RBC, hemoglobin, hematocrit, red blood cell indices (MCV, MCH, MCHC, RDW), plus platelets and MPV. It assists in detecting anemia type, infection, hydration status, or bone marrow issues. This test offers insight into oxygen delivery, clotting status, immune function, and systemic wellness.

Blood
Blood Draw

The Histamine Plasma Test measures histamine levels in the blood to help evaluate allergic reactions, mast cell disorders, or other conditions linked to abnormal histamine release. Elevated levels may indicate allergies, mastocytosis, or anaphylaxis, while low levels can affect digestive and immune function.

Blood
Blood Draw

The HLA (Human Leukocyte Antigen) Typing for Celiac Disease test is a genetic test that identifies specific HLA gene variants associated with an increased risk of developing celiac disease. Celiac disease is an autoimmune disorder triggered by the ingestion of gluten, a protein found in wheat, barley, and rye. This test aids in assessing the genetic predisposition to celiac disease.

Blood
Blood Draw
Also Known As: Tissue Typing Test, HLA Typing Test, Histocompatibility Test, HLA Crossmatching Test, HLA Screening Test

Most Popular

The High-Sensitivity C-Reactive Protein (hs-CRP) Test measures very low levels of CRP in blood to evaluate inflammation and cardiovascular risk. Elevated hs-CRP may indicate increased risk for heart disease, heart attack, or stroke even before symptoms appear. Doctors use this test along with cholesterol and other markers to assess overall heart health, guide prevention strategies, and monitor treatment. It also helps evaluate chronic inflammation and metabolic conditions.

Blood
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Also Known As: Cardiac CRP Test, High Sensitivity C-Reactive Protein Test

The Hypersensitivity Pneumonitis Screen detects IgG precipitins to inhaled antigens—such as Aspergillus fumigatus, Micropolyspora faeni, and pigeon serum—to support evaluation of hypersensitivity pneumonitis. Positive precipitins help identify antigen sensitization linked to interstitial lung inflammation and guide further diagnostic workup.

Blood
Blood Draw

The IA-2 Antibody Test measures autoantibodies against the islet antigen-2 protein, associated with pancreatic beta cell destruction in type 1 diabetes. Positive IA-2 antibodies can help identify autoimmune activity before clinical onset, supporting risk assessment, early diagnosis, and monitoring of disease progression in individuals with suspected or confirmed autoimmune diabetes.

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Blood Draw

The IgA Subclasses Panel evaluates IgA1 and IgA2 subclasses, which are critical for mucosal defense and immune balance. Deficiencies may increase susceptibility to sinus, lung, or digestive infections and may also be linked to autoimmune disease. This test supports assessment of antibody function, systemic health, and conditions tied to mucosal immunity and immune dysregulation.

Blood
Blood Draw

Most Popular

The Immunoglobulin A (IgA) Test measures IgA antibody levels in blood to evaluate immune system health and mucosal defense in the respiratory and digestive tracts. Low IgA may indicate immune deficiency, celiac disease, or recurrent infections, while high levels may suggest autoimmune disorders, liver disease, or chronic inflammation. Doctors use this test to assess unexplained illness or immune imbalance. Results provide key insight into antibody function and overall immunity.

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Blood Draw
Also Known As: Immunoglobulin A Test, Immunoglobulin A Antibody Test, IgA Antibody Test

Most Popular

The Immunoglobulin E (IgE) Test measures IgE antibody levels in blood to evaluate allergic reactions, asthma, and immune response. Elevated IgE may indicate allergies to food, pollen, or other triggers, as well as eczema or parasitic infections. Doctors order this test to investigate symptoms like hives, sneezing, or wheezing and to guide allergy treatment. Results provide vital insight into immune health, allergic sensitivity, and overall diagnostic care.

Blood
Blood Draw
Also Known As: Immunoglobulin E Test, Immunoglobulin E Antibody Test, IgE Antibody Test

The IgG Subclasses Panel measures four IgG antibody subclasses (IgG1, IgG2, IgG3, IgG4) to assess immune system function. Abnormal levels may indicate primary immunodeficiency, recurrent infections, autoimmune disease, or allergic conditions. Doctors order this test for patients with chronic sinus, lung, or ear infections or suspected immune imbalance. Results provide key insight into antibody response, guiding diagnosis, treatment, and long-term immune monitoring.

Blood
Blood Draw
Also Known As: IgG Subclasses Test

Most Popular

The Immunoglobulin G (IgG) Test measures IgG antibody levels in blood to assess immune system function and long-term response to infections. Low IgG may indicate immune deficiencies or recurrent infections, while high levels may signal chronic inflammation, autoimmune disease, or certain infections. Doctors use this test to evaluate unexplained illness, monitor immune disorders, or assess overall immunity. Results provide vital insight into immune health and disease management.

Blood
Blood Draw
Also Known As: Immunoglobulin G Test, Immunoglobulin G Antibody Test, IgG Antibody Test

Most Popular

The Immunoglobulin M (IgM) Test measures IgM antibody levels in blood to evaluate immune response and early defense against infections. High IgM may indicate recent or acute infections, autoimmune disease, or certain blood disorders, while low levels may suggest immune deficiency. Doctors order this test to investigate recurrent infections, unexplained inflammation, or suspected immune problems. Results provide vital insight into antibody health, immune status, and diagnostic care.

Blood
Blood Draw
Also Known As: Immunoglobulin M Test, Immunoglobulin M Antibody Test, IgM Antibody Test

The Immunofixation Serum Test identifies abnormal proteins in the blood called monoclonal immunoglobulins, often linked to multiple myeloma, Waldenström macroglobulinemia, or other plasma cell disorders. Physicians use this test to detect, classify, and monitor abnormal antibody production. Results help confirm suspected conditions, assess disease progression, and guide ongoing management of disorders affecting immune system function.

Blood
Blood Draw

People tend to overlook their digestive health. With so much focus on cancer, heart attacks, and strokes, it's easy for your gut health to get lost in the shuffle. 

That's why it's vital to have digestive lab tests done regularly. Catching digestive system conditions before they start is the best way to treat them. 

If monitoring your gut health is new to you, don't worry. In this article, we're going to cover everything you need to know about your gut.  

Digestive System Conditions 

There are different kinds of gastrointestinal lab tests to monitor different enzymes and bacteria in your gut. The bacteria in your gut is known as "good bacteria." These bacteria need to maintain their presence in your stomach for the system to remain healthy in the long run. An unhealthy digestive system can give rise to the following conditions.

Celiac Disease 

This is an acute gluten sensitivity in the digestive system. People with celiac disease suffer from an immune response triggered in the small intestine whenever they eat foods containing gluten. Gluten is common in flour and wheat-based products. If you don't treat celiac disease, it can affect the absorption of nutrients in your small intestines, and the lining of your small intestine will begin to deteriorate over time. The damage done by celiac disease to your small intestines can lead to more severe complications in the future. 

Symptoms of Celiac Disease include: 

  • Fatigue 
  • Diarrhea 
  • Abdominal pain 
  • Bloating 
  • Constipation 
  • Weight loss 
  • Nausea and vomiting 

Inflammatory Bowel Disease (IBD) 

Inflammatory Bowel Disease is a blanket term that covers several conditions that affect the bowels. The two major types of inflammatory bowel disease are colitis & Crohn's disease. Ulcerative colitis involves ulcers and inflammation along the lining of the large intestine. This condition can affect your rectum and colon too. Crohn's disease has similar symptoms to colitis and also involves the swelling of the digestive tract. Crohn's can affect the deeper layers of the digestive tract. 

Symptoms Of Inflammatory Bowel Disease include:

  • Abdominal pain 
  • Diarrhea 
  • Fatigue 
  • Fast weight loss 
  • Loss of appetite 
  • Blood in stools  

Inflammatory Bowel Syndrome (IBS) 

IBS affects the lower and upper regions of the GI tract. The condition can affect the small intestines, large intestines, and colon at the same time—people suffering from IBS experience chronic constipation, chronic diarrhea, or both. Medical experts believe that IBS occurs due to severe food poisoning. 

Lactose Intolerance 

Lactose intolerance is the inability to digest lactose. This condition occurs due to a lack of lactase enzymes in the digestive system. Lactase is the enzyme responsible for processing lactose in the body. When lactase levels are low in a person's body, they may suffer from lactose intolerance.  

Symptoms Of Lactose Intolerance include:

  • Bloating 
  • Diarrhea 
  • Gas 
  • Pancreatic disease 
  • Stomach cramps 
  • Nausea and vomiting   

Pancreatic Diseases

Problems in your digestive tract can result in several pancreatic diseases, including acute pancreatitis. If you don't treat acute pancreatitis on time, it can lead to much bigger problems in the long run. 

Symptoms Of Pancreas Malfunction include:

  • Nausea and vomiting 
  • Excess gas 
  • Abdominal pain and swelling 
  • Weight loss 
  • Malnutrition 
  • Fever 
  • Light-colored stools  
  • Foul-smelling stools 
  • Diarrhea 

If you have any of these symptoms for more than 2-3 days, make sure you consult a doctor.  

Peptic Ulcers 

Peptic ulcers develop in the inner lining of the stomach. They usually affect the upper section of the small intestine and occur as duodenal ulcers or gastric ulcers. While duodenal ulcers occur in the upper section of the small intestine or the duodenum, gastric ulcers will occur in the stomach.  

Symptoms Of Peptic Ulcers include:

  • Bloating 
  • Feeling full 
  • Heartburn 
  • Belching 
  • Nausea 
  • Burning pain in the stomach 
  • Intolerance to fatty foods 

Lab Tests for Digestive Conditions 

Digestive lab tests help screen, diagnose, and monitor various digestive conditions. Two of the most common and effective digestive lab tests are the stool culture and fecal occult test. The fecal occult test checks for blood in your stool. The test is conducted by placing a fecal sample on a special card. The card is then sent to a lab for testing. The stool culture test searches for abnormal bacteria in the stool, and results will take at least 2-3 days. 

In addition to the above tests, doctors can use imaging tests to take an in-depth look at a patient's digestive system.  

Here are some of the most popular procedures to monitor digestive conditions: 

  • Lower GI series 
  • CT or CAT scan 
  • MRI 
  • Upper GI series 
  • Colonoscopy 
  • Ultrasound 

Digestive System Lab Tests FAQs 

Digestive conditions cover a wide range of diseases affecting the digestive system of a person. If you don't know what you are looking for, it is easy for these conditions to be overlooked. Here are some of the most common FAQs about digestive disorders and lab tests: 

Q. What are the most common problems in the GI tract? 

Heartburn, IBS, and cancer are some of the most common conditions that affect a person's digestive system. Rectal problems such as fissures and hemorrhoids also can occur.  

Q. What are the most common signs and symptoms of digestive conditions? 

  • Abdominal pain 
  • Bloating 
  • Swelling 
  • Belching 
  • Diarrhea 
  • Gas  
  • Fatigue 
  • Constipation 

If you experience any of these symptoms regularly, you should consult a doctor. 

Q. Does bloodwork reveal digestive problems? 

Yes. Your doctor can order blood tests to diagnose a digestive problem. The tests will check for levels of specific substances in the blood. Bloodwork is common in diagnosing Celiac disease, ulcerative colitis, or Crohn's disease. 

Solving Your Digestive Problems 

Ulta Lab Tests offers highly accurate and reliable tests so that you can make informed decisions about your health. Here are some things that you will love about Ulta Lab Tests: 

  • You don't need health insurance 
  • Your results are confidential and secure 
  • We offer affordable rates for lab tests 
  • You don't need a physician's referral 
  • 100% satisfaction guarantee 

Take control with Ulta Lab Tests today!