Scleroderma

The Scleroderma Scl-70 Antibody Test detects antibodies to topoisomerase I, strongly associated with systemic scleroderma. A positive result may indicate diffuse cutaneous systemic sclerosis, often linked to lung, kidney, or heart involvement. Doctors use this blood test to confirm diagnosis, evaluate unexplained symptoms such as skin thickening or joint pain, and guide monitoring and treatment of autoimmune connective tissue diseases.

The ANA Screen IFA with Reflex to Titer and Pattern Test detects antinuclear antibodies in blood to evaluate autoimmune activity. If positive, further testing identifies antibody concentration (titer) and fluorescence pattern, helping diagnose conditions like lupus, rheumatoid arthritis, or Sjögren’s syndrome. Doctors order this test to investigate symptoms such as joint pain, fatigue, rash, or swelling and to guide treatment for autoimmune and connective tissue disorders.

The ANA IFA Panel Comprehensive screens for autoimmune disorders by detecting antinuclear antibodies and specific markers including dsDNA, Sm, Sm/RNP, Scl-70, and Sjögren’s SS-A/SS-B. Doctors order this panel for patients with joint pain, rash, fatigue, or suspected lupus, scleroderma, or Sjögren’s syndrome. Results provide critical insight into autoimmune activity, helping confirm diagnosis, monitor disease progression, and guide treatment decisions.

The Centromere B Antibody Test detects antibodies to centromere protein B, a marker often associated with CREST syndrome and systemic sclerosis. Presence of these antibodies may indicate autoimmune connective tissue disease or vascular complications. This test provides insight into autoimmune activity, systemic immune response, and conditions linked to antibody-mediated tissue and organ involvement.

The Complete Blood Count with Differential and Platelets Test is a comprehensive blood test that checks red blood cells, white blood cells, hemoglobin, hematocrit, and platelets. The differential analyzes types of white blood cells to detect infections, anemia, clotting abnormalities, immune conditions, and certain cancers. This essential test is often ordered for routine health exams, diagnosis, and monitoring treatment progress.

The Comprehensive Metabolic Panel (CMP) Test measures 21 markers to assess metabolic health, liver and kidney function, and electrolyte balance. It includes glucose, calcium, sodium, potassium, chloride, CO2, albumin, globulin, A/G ratio, total protein, bilirubin, ALP, AST, ALT, BUN, creatinine, BUN/creatinine ratio, and eGFR. The CMP helps detect diabetes, liver or kidney disease, and supports routine screening and chronic condition monitoring.

The Jo-1 Antibody Test measures antibodies that target histidyl-tRNA synthetase, often associated with autoimmune myositis and interstitial lung disease. This marker helps reveal autoimmune-related muscle inflammation, chronic lung symptoms, and joint pain. Results provide insights into underlying immune activity, assisting providers in diagnosis, treatment planning, and ongoing disease management for connective tissue disorders.

The Rheumatoid Factor (RF) Test measures RF antibodies in blood to help diagnose rheumatoid arthritis and other autoimmune conditions. High RF levels may indicate rheumatoid arthritis, Sjögren’s syndrome, or other connective tissue diseases, though they can also appear in some infections. Doctors order this test to investigate joint pain, stiffness, or swelling. Results provide important insight into autoimmune activity, joint health, and inflammatory disease management.

The RNP Antibody Test detects antibodies to ribonucleoprotein, an autoantigen linked to connective tissue and autoimmune diseases. Elevated levels may indicate mixed connective tissue disease, systemic lupus erythematosus, or other autoimmune disorders. This test provides valuable insight into immune system activity and is often performed alongside ANA and ENA panels for a broader evaluation of autoimmune health.

The Sm and Sm/RNP Antibodies Test detects autoantibodies associated with systemic lupus erythematosus (SLE) and mixed connective tissue disease (MCTD). Sm antibodies are highly specific for lupus, while Sm/RNP antibodies appear in MCTD and sometimes overlap syndromes. Physicians use this test to support diagnosis, evaluate autoimmune activity, and guide monitoring alongside other clinical findings and laboratory markers.

The T3 Reverse (rT3) Test measures reverse triiodothyronine, an inactive thyroid hormone, to assess thyroid and metabolic function. High rT3 may occur in hypothyroidism, chronic illness, stress, or during certain treatments, while low levels may reflect hormone imbalance. Doctors use this test along with TSH, Free T4, and Free T3 to evaluate fatigue, weight changes, or slow metabolism. The rT3 Test provides insight into thyroid regulation, energy balance, and endocrine health.

The T3 Total Test measures total triiodothyronine (T3), a combination of both bound and unbound (free) T3, to assess thyroid function. Abnormal levels may indicate hyperthyroidism, hypothyroidism, goiter, or pituitary disorders. Doctors use this test to evaluate symptoms like fatigue, weight changes, anxiety, or irregular heartbeat and to monitor thyroid treatment. The T3 Total Test provides essential insight into metabolism, energy regulation, and overall endocrine health.

The T3 Free Test measures free triiodothyronine (T3), the active thyroid hormone not bound to proteins, to assess thyroid function. It helps diagnose hyperthyroidism, hypothyroidism, goiter, and pituitary disorders. Doctors order this test to evaluate symptoms like fatigue, weight changes, anxiety, or irregular heartbeat and to monitor thyroid replacement or antithyroid therapy. The Free T3 Test provides key insight into metabolism, energy regulation, and overall endocrine health.

The T4 Total Test measures total thyroxine (T4) in blood, a combination of both bound and unbound (free) T4, to assess thyroid function. Abnormal levels may indicate hypothyroidism, hyperthyroidism, goiter, or pituitary disorders. Doctors use this test to evaluate symptoms like fatigue, weight changes, hair loss, or irregular heart rate and to monitor thyroid replacement or antithyroid therapy. The T4 Total Test provides key insight into metabolic, hormonal, and endocrine health.

The T4 Free Test measures the level of free thyroxine (T4) in blood, the active thyroid hormone not bound to proteins. It helps diagnose thyroid disorders such as hypothyroidism, hyperthyroidism, and goiter, as well as pituitary conditions affecting hormone regulation. Doctors use this test to evaluate symptoms like fatigue, weight changes, hair loss, or irregular heartbeat and to monitor thyroid replacement or antithyroid therapy, providing insight into metabolic and endocrine health.

The Thyroid Peroxidase and Thyroglobulin Antibodies Test measures TPO and TgAb antibodies that target thyroid enzymes and proteins essential for hormone production. High levels are linked to autoimmune thyroid disorders such as Hashimoto’s thyroiditis and Graves’ disease. Doctors order this test to evaluate fatigue, weight changes, neck swelling, or irregular heartbeat and to confirm thyroid autoimmunity. It provides vital insight into thyroid function and endocrine health.

The Thyroid Stimulating Hormone (TSH) Test measures TSH levels in blood to assess thyroid function and diagnose hypothyroidism or hyperthyroidism. It evaluates how the thyroid controls metabolism, energy, weight, and heart rate. Doctors use the TSH test to investigate symptoms such as fatigue, hair loss, or mood changes. Frequently included in routine health exams, it is also key for monitoring thyroid disease treatment and overall endocrine balance.

The Thyroid Stimulating Immunoglobulin (TSI) Test detects antibodies that stimulate the thyroid gland, often causing hyperthyroidism and Graves’ disease. High TSI levels may lead to symptoms such as weight loss, rapid heartbeat, or eye problems. Doctors order this test to confirm Graves’ disease, monitor treatment, or assess relapse risk. Results provide essential insight into autoimmune thyroid disorders and guide personalized management strategies.

The Urinalysis Complete Test evaluates urine for physical, chemical, and microscopic properties to assess kidney health, urinary tract infections, diabetes, and metabolic disorders. It measures appearance, concentration, pH, protein, glucose, ketones, blood, bilirubin, nitrites, leukocyte esterase, and microscopic cells or crystals. Doctors use this test in routine exams, to diagnose urinary symptoms, and to monitor chronic kidney or metabolic disease.

 A Urinalysis Screen test is a common diagnostic tool used in healthcare to assess and monitor various disorders by analyzing a patient's urine. This test encompasses a range of examinations including physical, chemical, and microscopic aspects of urine. It's a non-invasive, quick, and often revealing test that can provide significant insights into a person's health.