Rheumatoid Arthritis Diagnostic IdentRA® Panel 2

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Rheumatoid Arthritis Diagnostic Panel Identra With 1433 Eta

Cyclic Citrullinated


Rheumatoid Factor

Rheumatoid factor (RF) is a blood test that measures the amount of the RF antibody in the blood. An abnormal result means the test is positive, which means higher levels of rheumatoid factor have been detected in your blood. Most patients with rheumatoid arthritis or Sjogren syndrome have positive RF tests. The higher the level, the more likely one of these conditions is present. Not everyone with higher levels of rheumatoid factor has rheumatoid arthritis or Sjogren syndrome.
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The Rheumatoid Arthritis Diagnostic IdentRA® Panel 2 test contains 1 test with 3 biomarkers.

Clinical Significance

Rheumatoid Arthritis Diagnostic Panel 2 - Autoantibody testing has a major role in the diagnosis of RA. This panel includes Rheumatoid factor (RF), anti-cyclic citrullinated peptide (CCP) and anti-mutated citrullinated vimentin (MCV). RF is found in a majority of patients with RA but is not specific for the diagnosis. Anti-CCP antibody is more sensitive and highly specific. RF and anti-CCP are included in the most recent classification criteria for RA. The past several years have seen a search for biomarkers which might increase sensitivity in order to identify the minority of RA patients who are negative for either RF or CCP, especially early in the course of disease. The addition of anti-MCV increases sensitivity for RA when tested together with RF and CCP.

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