Titer

Find the correct immunity detection and titer testing with Ulta Lab Tests to monitor your immune levels with an accurate reading of your confidential results in 24 to 48 hrs.


Name Matches

Diphtheria and Tetanus Antitoxoids

Clinical Significance

Diphtheria and Tetanus Antitoxoids - Used to evaluate diphtheria immunization response. Antibody levels of > or = to 0.10 IU/mL are considered protective. For Pre and Post vaccination testing to assess normal immune response, please refer to Test Code 10680, Diphtheria Antitoxoid, Pre and Post Vaccination.

Tetanus is caused by Clostridium tetani. Immunization with Tetanus Antitoxoid is effective with boosters in immunocompetent individuals. Antibody levels of > or = to 0.10 IU/mL are considered protective. However, tetanus can still occur in some individuals with such antibody levels. These results should not be used to determine the necessity to administer antitoxin when clinically indicated. For Pre and Post vaccination testing to assess normal immune response, please refer to Test Code 91424, Tetanus Antitoxoid, Pre and Post Vaccination.

Diphtheria Antitoxoid≥0.10 IU/mLTetanus Antitoxoid≥0.10 IU/mL

 

 



Clinical Significance

Used to evaluate diphtheria immunization response. Antibody levels of > or = to 0.10 IU/mL are considered protective. For Pre and Post vaccination testing to assess normal immune response, please refer to Test Code 10680, Diphtheria Antitoxoid, Pre and Post Vaccination.

 

Alternative Name(s)

DPT Titer,Anti Diphtheria


Hepatitis A & B Titer Test

  • Hepatitis A Antibody, Total
  • Hepatitis A IgM Antibody
  • Hepatitis B Surface Antigen with Reflex Confirmation
  • Hepatitis B Surface Antibody Immunity, Quantitative
  • Hepatitis B Core Antibody, Total

The Hepatitis A & B Titer Test is ordered when a person needs proof of immunity to Hepatitis A and B or just want to check their immune status.

The Hepatitis Titer Test includes immunity testing for both Hepatitis A and B.  Hepatitis is a viral disease which affects the liver.  Vaccinations for Hepatitis A and B can provide protective antibodies which immunize a person from catching the virus.  Additionally, a person who has been affected by Hepatitis A or B and recovers can develop natural immunity.  Titer testing looks for the antibodies which typically indicate that a person is immune to a particular virus or infection.

Hepatitis B Immunity

Not Immune and no active or prior infection; may be a good candidate for vaccine

  • Hepatitis B Surface Antigen (HBsAg) = Negative
  • Hepatitis B Surface Antibody (Anti-HBs) = Negative
  • Hepatitis B Core Antibody, Total (Anti-HBc IgG+IgM) = Negative

Immunity due to vaccination

  • Hepatitis B Surface Antigen (HBsAg) = Negative
  • Hepatitis B Surface Antibody (Anti-HBs) = Positive
  • Hepatitis B Core Antibody, Total (Anti-HBc IgG+IgM) = Negative

HEPATITIS B INFECTION

  • Hepatitis B Surface Antigen (HBsAg) = Positive  A positive result indicates an infection, usually with symptoms; contagious; could also be a flare of a chronic infection

Hepatitis A immunity

Immunity

  • Hepatitis A Antibody, Total = Positive
  • Hepatitis A IgM Antibody = Negative

No active infection but previous HAV exposure; has developed immunity to HAV or recently vaccinated for HAV

No Immunity

  • Hepatitis A Antibody, Total= Negative
  • Hepatitis A IgM Antibody = Negative

No current or previous HAV infection; vaccine may be advised if at risk

HEPATITIS A INFECTION

  • Hepatitis A IgM Antibody = Positive   A positive result indicates an acute or recent infection

 


Hepatitis A Antibody, Total (IgM - IgG)

Hepatitis A Total (IgM - IgG) Blood Test is used to help diagnose a liver infection due to the hepatitis A virus. There are several causes of hepatitis and the accompanying symptoms, so this test may be used to determine if the symptoms are due to hepatitis A.

The total Hepatitis A antibody test detects both IgM and IgG antibodies and thus may be used to identify both current and past infections. This test will also be positive after receiving the vaccine, so sometimes it may be used to determine whether a person has developed immunity after vaccination.

  • A positive result Hepatitis A Antibody, Total that is not accompanied with Hepatitis A IgM test indicates  exposure to hepatitis A vairus but does not rule out acute infection. 
  • A Negative result Hepatitis A Antibody, Total that is not accompanied with Hepatitis A IgM test indicates no current or previous HAV infection; vaccine may be recommended if at risk.

Results of this hepatitis testing may indicate the following.

A total antibody test detects both IgM and IgG antibodies but does not distinguish between them.

If the total antibody test or hepatitis A IgG result is positive and someone has never been vaccinated against HAV, then the person has had past exposure to the virus. About 30% of adults over age 40 have antibodies to hepatitis A.


Hepatitis A IgM Antibody & Total A Antibody Panel conatins the following 2 tests.

  • Hepatitis A IgM Antibody
  • Hepatitis A Antibody, Total

This test is used to help diagnose a liver infection due to the hepatitis A virus. There are several causes of hepatitis and the accompanying symptoms, so this test may be used to determine if the symptoms are due to hepatitis A.

Hepatitis A Antibody, Total

The total Hepatitis A antibody test detects both IgM and IgG antibodies and thus may be used to identify both current and past infections. This test will also be positive after receiving the vaccine, so sometimes it may be used to determine whether a person has developed immunity after vaccination.

Hepatitis A IgM Antibody

The Hepatitis A IgM antibody test detects the first antibody produced by the body when it is exposed to hepatitis A. This test is used to detect early or recent infections and to diagnose the disease in people with symptoms of acute hepatitis. IgM antibodies to Hepatitis A suggest a current, acute or recent Hepatitis A infection.

Results of this hepatitis testing may indicate the following.

If Hepatitis A IgM Antibody is positive the resulkts indicate Acute or recent Hepatitis A virus infection.

If Hepatitis A IgM Antibody is negative and the Hepatitis A Antibody, Total is positive then the results indicate no active infection but previous Hepatitis A virus exposure; has developed immunity to Hepatitis A virus or recently vaccinated for Hepatitis A virus.


Hepatitis A IgM Antibody

This test is used to screen for recent exposure to the Hepatitis A virus.and to help diagnose a liver infection due to the Hepatitis A virus. There are several causes of hepatitis and the accompanying symptoms, so this test may be used to determine if the symptoms are due to Hepatitis A.

Hepatitis A IgM Antibody

The Hepatitis A IgM antibody test detects the first antibody produced by the body when it is exposed to Hepatitis A. This test is used to detect early or recent infections and to diagnose the disease in people with symptoms of acute hepatitis. IgM antibodies to Hepatitis A suggest a current, acute or recent Hepatitis A infection.

Results of this hepatitis testing may indicate the following:

  • If Hepatitis A IgM Antibody is positive the results indicate Acute or recent Hepatitis A virus infection.
  • If Hepatitis A IgM Antibody is negative and the Hepatitis A Antibody, Total is positive then the results indicate no active infection but previous Hepatitis A virus exposure; has developed immunity to Hepatitis A virus or recently vaccinated for Hepatitis A virus.
  • Dietary supplements containing biotin may interfere in assays and may skew analyte results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.

This assay does not distinguish between Total B core antibody IgG and IgM detected before or at the onset of symptoms; however, such reactivity can persist for years after illness, and may even outlast anti-HBs. Occasionally Hepatitis B core antibody may be the only marker of either current or past Hepatitis B infection.


Hepatitis B Surface Antibody, Quantitative (anti-HBs

Detects antibody produced in response to HBV surface antigen. It is used to detect previous exposure to HBV; it can also develop from successful vaccination so it is used to determine the need for vaccination (if anti-HBs is absent) or to determine if a person has recovered from an infection and is immune (cannot get the infection again).

Clinical Significance

This assay is used to determine immune status for Hepatitis B as ≥10 mIU/mL as per CDC Guidelines.


Hepatitis B Surface Antigen with Reflex Confirmation: Positive samples will be confirmed

IMPORTANT:  NOTE THIS IS A REFLUX TEST - The price charged for this test is only for the Hepatitis B Surface Antigen. ADDITIONAL CHARGES WILL OCCUR FOR THE REFLUX CONFIRMATION if the Hepatitis B Surface Antigen is positive.

Hepatitis B surface antigen (HBsAG) Detects protein that is present on the surface of the virus.  It is used to screen for, detect, and help diagnose acute and chronic hepatitis B virus (HBV) infections; earliest routine indicator of acute hepatitis B and frequently identifies infected people before symptoms appear; undetectable in the blood during the recovery period; it is the primary way of identifying those with chronic infections, including "hepatitis B virus (HBV) carrier" state.

Clinical Significance

Surface antigen usually appears in the serum after an incubation period of 1 to 6 months following exposure to Hepatitis B virus and peaks shortly after onset of symptoms. It typically disappears within 1 to 3 months. Persistence of Hepatitis B surface antigen for greater than 6 months is a prognostic indicator of chronic Hepatitis B infection.


Hepatitis B Titer Test

  • Hepatitis B Surface Antigen with Reflex Confirmation
  • Hepatitis B Surface Antibody Immunity, Quantitative
  • Hepatitis B Core Antibody, Total

The Hepatitis B Titer Test is ordered when a person needs proof of immunity to Hepatitis B or just want to check their immune status.

The Hepatitis Titer Test includes immunity testing for Hepatitis B.  Hepatitis is a viral disease which affects the liver.  Vaccinations for Hepatitis B can provide protective antibodies which immunize a person from catching the virus.  Additionally, a person who has been affected by Hepatitis B and recovers can develop natural immunity.  Titer testing looks for the antibodies which typically indicate that a person is immune to a particular virus or infection.

Hepatitis B Immunity

Not Immune and no active or prior infection; may be a good candidate for vaccine

  • Hepatitis B Surface Antigen (HBsAg) = Negative
  • Hepatitis B Surface Antibody (Anti-HBs) = Negative
  • Hepatitis B Core Antibody, Total (Anti-HBc IgG+IgM) = Negative

Immunity due to vaccination

  • Hepatitis B Surface Antigen (HBsAg) = Negative
  • Hepatitis B Surface Antibody (Anti-HBs) = Positive
  • Hepatitis B Core Antibody, Total (Anti-HBc IgG+IgM) = Negative

HEPATITIS B INFECTION

  • Hepatitis B Surface Antigen (HBsAg) = Positive  A positive result indicates an infection, usually with symptoms; contagious; could also be a flare of a chronic infection.

Hepatitis C Antibody, HCV RNA & Liver Panel

  • Hepatitis C Antibody
  • Hepatitis C Virus RNA, Quantitative, Real-Time PCR
  • Hepatic Function Panel

Hepatitis C antibody tests are used to screen individuals for the infection, including, people with no signs or symptoms but with risk factors, people who have symptoms associated with hepatitis or liver disease, or those who have been exposed to the virus.

Since the antibody test can remain positive for most people even if they have cleared the infection, this panel includes a hepatitis C RNA test, which detects the genetic material of the virus. A positive result on the RNA test means the virus is present, the infection has not resolved, and the person may require treatment. The liver panel is included to assess the health of the liver.

An HCV antibody test is typically reported as "positive" or "negative."

Results of Hepatitis C Virus RNA testing are reported as a number if virus is present. If no virus is present or if the amount of virus is too low to detect, the result is often reported as "negative" or "not detected."

Interpretation of the HCV screening and follow-up tests is shown below. In general, if the HCV antibody test is positive, then the individual tested is infected or has likely been infected at some time with hepatitis C. If the Hepatitis C Virus RNA test is positive, then the person has a current infection. If no Hepatitis C Virus RNA is detected, then the person either does not have an active infection or the virus is present in very low numbers.

HCV Antibody = Negative

No infection or too early after exposure for the test to be accurate; if suspicion remains high, retesting at a later time may be required.

_________________________

HCV Antibody = Positive or Indeterminate

HCV RNA = Negative

Past infection or no infection (false-positive screen); additional testing if indicated

_____________________

HCV Antibody = Positive or Weak or Indeterminate

HCV RNA = Positive

Current infection


Measles, also known as Rubeola, causes fever, irritability, respiratory illness, and the characteristic skin rash. Immunization has greatly diminished the incidence of measles. The presence of IgG is consistent with immunity or prior exposure. IgM is consistent with current or recent infection. IgM tests can generate false positive results and low levels of IgM can persist for longer than 12 months.

Measles Antibody IgG - to establish whether you have immunity to measles due to a previous infection or to vaccination.

Measles, also known as rubeola, causes fever, irritability, respiratory illness, and the characteristic skin rash. Immunization has greatly diminished the incidence of measles. The presence of IgG is consistent with immunity or prior exposure. 

Alternate Test Name: Measles Immunity Test



MMR (IgG) Panel (Measles, Mumps, Rubella) Titers - Includes Measles Antibody (IgG), Mumps Antibody (IgG), Rubella Immune Status

This panel provides presumptive evidence of immunity to measles, mumps, and rubella for purposes of routine vaccination, for students at post-high school educational institutions, and for international travelers.

 


Rubella is an acute exanthematous viral infection of children and adults. Rash, fever and lymphadenopathy characterize the illness. While many infections are subclinical, this virus has the potential to cause fetal infection with resultant birth defects. Diagnosis of a Rubella infection is best made serologically. In the absence of a current or recent infection, a demonstration of specific IgG on a serum sample is evident of immunity to Rubella.

Rubella is an acute exanthematous viral infection of children and adults. Rash, fever and lymphadenopathy characterize the illness. While many infections are subclinical, this virus has the potential to cause fetal infection with resultant birth defects. In the absence of a current or recent infection, a demonstration of specific IgG on a serum sample is evidence of immunity to rubella. A positive rubella IgM result does not necessarily indicate current or recent infection. Without a history of exposure to rubella or symptoms consistent with rubella, the IgM result may be difficult to interpret. Rubella IgM can be false positive due to other causes (e.g., parvovirus, rheumatoid factor, cytomegalovirus). Rubella IgM may also persist for more than 12 months after vaccination or natural infection. For a serologic diagnosis of congenital rubella in the neonatal period, antibody to rubella virus should be measured in both infant and maternal sera. If IgM is detected in a newborn infants serum, it is probable that transplacental rubella infection has occurred.

Syphilis (RPR + FTA-ABS)

  • FTA-ABS - Treponema pallidum Ab (Confirmation for Syphilis RPR test).
  • Syphilis RPR ( RPR (Monitor) with Reflex to Titer)

FTA-ABS - Treponema pallidum Ab

Clinical Significance

The FTA-ABS is a specific treponemal assay to detect antibody to t. Pallidum. The FTA-ABS becomes reactive 4-6 weeks after infection. Unlike the nontreponemal tests, once the FTA-ABS test becomes reactive, it will remain reactive for many years. Since the reactivity found with the FTA-ABS does not indicate response to therapy, it is not suitable for monitoring treatment. The FTA-ABS test does not distinguish between syphillis and other treponematoses such as yaws, pinta and bejil.

The treponemal antibody test (FTA-ABS) is often used as an initial test. A positive result indicates the presence of syphilis antibodies in the blood, but since treponemal antibodies remain positive even after an infection has been treated, it does not indicate whether the person has a current infection or was infected in the past. Conversely, nontreponemal antibodies as detected with an RPR typically disappear in an adequately treated person after about 3 years. Thus, if an initial treponemal test is positive, an RPR can be performed to differentiate between an active or past infection. In this case, a positive RPR would confirm that the person has been exposed to syphilis and, if not treated previously, has an active infection or, if treatment had occurred more than 3 years ago, possible re-infection.

Alternative Name(s) 

Treponemal pallidum, Fluorescent Treponemal Antigen, Syphilis

 

Syphilis RPR ( RPR (Monitor) with Reflex to Titer)

Reference Range(s)

Non-Reactive

Clinical Significance

This is a non-treponemal screening test for syphilis. False positive results may occur due to systemic lupus erythematosus, leprosy, brucellosis, atypical pneumonia, typhus, yaws, pinta, or pregnancy. Monitoring of RPR is helpful in assessing effectiveness of therapy.

IMPORTANT

A positive RPR screen and a positive result on the FTA-ABS confirms the screening result and the affected person is diagnosed with syphilis.

A negative result on the treponemal test may mean that the initial RPR test was falsely positive. Further testing and investigation may be done to determine the cause of the false positive.

Limitations

False-positive results have been associated in patients with infections, pregnancy, autoimmune disease, old age, Gaucher disease, and malignancy.

Alternative Name(s) 

Syphilis



Tetanus Antitoxoid (Titer)

Clinical Significance

Tetanus is caused by Clostridium tetani. Immunization with Tetanus Antitoxoid is effective with boosters in immunocompetent individuals. Antibody levels > or = to 0.10 IU/mL are considered protective. However, tetanus can still occur in some individuals with such antibody levels. These results should not be used to determine the necessity to administer antitoxin when clinically indicated. For Pre and Post vaccination testing to assess normal immune response, please refer to Test Code 91424, Tetanus Antitoxoid, Pre and Post Vaccination.

 

 


Varicella-Zoster Virus (VZV) causes chicken pox and when reactivated, potentially decades later, causes shingles. Twenty percent of adults will develop shingles, a rash or blister of the skin that may cause severe pain. Varicella-Zoster IgG, EIA reliably measures immunity due to previous infection, but is unsuitable for detection of post-vaccination immune status.

The Varicella Zoster Virus Antibodies, IgG test is typically done to check for immunity to the virus which causes chickenpox.  Varicella Zoster Virus is a member of the Herpes Virus family.  This test measures the level of antibodies produced by the immune system in response to the virus.  Results provide a numerical value for the antibody level which can be compared to a reference interval to determine immune status.  IgG antibodies are typically detectable a few weeks after the initial infection.  In the United States, many people are vaccinated against Varicella when they are young.  In most cases those who contract the virus and recover develop a natural immunity which protects them from catching it again. 

The most common condition which results from infection with Varicella is Chickenpox.  The infection causes an outbreak of an itchy rash and the development of small fluid-filled blisters.  During the primary infection, chickenpox is highly contagious and spread through coughing, sneezing or touching fluid from the blisters.  Most people recover without treatment and the virus remains latent in their system.  There is a possibility for the virus to reactivate later in life, especially in those with weakened immune systems.  This can cause shingles, a condition characterized by a painful burning or itching sensation on one or more areas of the body.  Shingles typically clear up after a few weeks as the virus becomes latent again.

The Varicella IgG Antibody Titer is usually ordered when someone is required to show proof of immune status for work or school.  It may also be done for organ transplant patients or pregnant women.

The Varicella Titer is also available as part of our Immunity Panel which includes other common titer tests.


Varicella Zoster Virus Antibodies (IgG, IgM)  

 


Varicella-Zoster Virus (VZV) causes chicken pox and when reactivated, potentially decades later, causes shingles. Twenty percent of adults will develop shingles, a rash or blister of the skin that may cause severe pain.


Vaccinations aren't as readily available as you may think. Many areas throughout the United States don't have the?healthcare access needed?to administer vaccinations to nearby areas. This leaves large chunks of the population at risk for developing preventable conditions.

Vaccinations are crucial, especially during a time when we're all on the go every single day. We need adequate protection from everyday ailments.

Even if you had all of your shots when you were younger, you might no longer have an immune response. This is why everyone needs immunity detection and titer testing.

This serological testing can help your healthcare provider determine what your immunization status is for different conditions. In response, you and your healthcare provider can make a plan for your healthcare moving forward.

To learn more about antibody testing and antibody titer options, keep reading.

What Is Immunity Detection and Titer Testing?

Overall, immunity detection and titer testing help you and your healthcare professional understand what conditions you do and do not have immunity against. Even if you've had the vaccine for a disease, it doesn't mean that your body retains the immunity past a few years.

These kinds of tests use a sample of your blood to test for an immune response. By exposing that sample of blood to the virus or bacteria that you're testing, you can see whether or not you're immune to the condition.

If you're not, you need to update your shots. It's important to stay up-to-date on all of your vaccines so that you're protected from these preventable diseases.

What Are the Risks for Low Immunity and Low Titer Levels?

The most common risk for low immunity is lack of vaccination. If you haven't gotten the vaccine for a particular condition, it's unlikely that your body will have a good immune response to the disease or virus. Even if you've had the disease before, your immune response may not be as strong as it should be.

Another risk for low immunity is receiving the vaccination for a condition a long time ago. Many of us get very important vaccinations near the beginning of our lives. If we don't update these shots as needed, we could lose immunity over time.

Lastly, individuals with immunodeficiencies could experience problems retaining proper immune responses. Their bodies don't have the strength necessary to fight some of these conditions. So, it's even more important for these individuals to get antibody testing to determine what vaccinations they need to update.

What Diseases Can You Test for Immunity and Titer Levels?

Fortunately, the scientific community has formed plenty of serological testing possibilities for different conditions. From measles to diphtheria, there's an immune response test.

If you're worried about a specific condition, you should ask your healthcare provider about vaccination against that particular condition.

You may work with patients who have chickenpox. You may be at a high risk for developing tetanus at work. Whatever the case, you should let your healthcare provider know so that they can help you come up with an immunization plan.

What Are the Signs and Symptoms of Low Immunity Detection and Low Titer Levels?

You're more likely to develop conditions if you have an impaired immune system or a low or nonexistent immune response. Specifically, you're going to be at risk for developing the disease(s) that you're not protected against.

If you happen to contract the disease that you're not protected against, you will show signs and symptoms that are consistent with the disease.

Unfortunately, there's no way to determine your immune response to a disease unless you get antibody testing or contract the disease. This is why we strongly encourage you to get your tests and vaccinations done now rather than worrying about how your body may react later.

How Are Immunity Detection and Titer Levels Diagnosed?

To measure your immune response to various conditions, you have to get lab work done. This is the only way to diagnose immunity before a live infection from the pathogen associated with the disease in question.

With a titer or immunity test, you'll have your blood drawn at a patient service center. Your blood specimen will be sent to a national laboratory where it will be tested for antibodies (an immune response) to the condition you are testing for.

If your specimen doesn't have a response, you're not immune to the condition.

The Lab Tests to Screen, Diagnose, and Monitor Immunity Detection and Titer Levels

There are plenty of lab tests for various conditions that you may want to check your immunity for.

At Ulta Labs, we offer immunity detection and titer testing for a variety of conditions:

Our antibody titer tests can help you determine whether or not you have the protection that you need from various conditions. It would be best if you never assumed that you're immune to a disease. Instead of guessing, you need to get real results from these antibody tests.

Get Your Immunity Detection and Titer Testing With Ulta Lab Tests

If you're looking to determine your immunization status, you need immunity detection and titer testing.

Ulta Lab Tests offers highly accurate and reliable tests so that you can make informed decisions about your health. Here are a few great things to love about Ulta Lab Tests:

  • You'll get secure and confidential results
  • You don't need health insurance
  • You don't need a physician's referral
  • You'll get affordable pricing
  • We offer a 100% satisfaction guarantee

Order your immunity detection and titer testing today and, your results will be provided to you securely and confidentially online in 24 to 48 hours for most tests.

Take control with Ulta Lab Tests today!