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The Sm Antibody Test measures antibodies against Smith antigens, strongly associated with systemic lupus erythematosus. It helps identify autoimmune activity, connective tissue disorders, and systemic inflammation. This test provides information about persistent symptoms including fatigue, arthritis, rash, or kidney involvement, supporting evaluation of lupus and related autoimmune disease.
The Thyroglobulin Antibodies (TgAb) Test detects antibodies that attack thyroglobulin, a protein essential for thyroid hormone production. Elevated levels may indicate autoimmune thyroid disorders such as Hashimoto’s thyroiditis or Graves’ disease. Doctors order this test to evaluate symptoms like fatigue, weight changes, neck swelling, or irregular heartbeat and to confirm thyroid disease. It provides key insight into autoimmune activity and overall thyroid function.
The Sjögren's SS-A Antibody Test detects SS-A (Ro) antibodies often linked to Sjögren’s syndrome, lupus, and other autoimmune disorders. These antibodies are associated with dry eyes, dry mouth, joint pain, and systemic inflammation. By measuring SS-A levels, the test supports evaluation of autoimmune activity, connective tissue disease, and overall immune system health in patients with persistent symptoms.
The Hepatitis Be Antibody (anti-HBe) Test is a qualitative blood test that detects antibodies to the hepatitis B e antigen and reports results as Reactive or Non-Reactive. A reactive result often indicates lower infectivity and a transition toward recovery or inactive disease, while a non-reactive result suggests no antibodies were detected. Doctors use this test to monitor hepatitis B infection stage, evaluate treatment response, and support long-term disease management.
The Scleroderma Scl-70 Antibody Test detects antibodies to topoisomerase I, strongly associated with systemic scleroderma. A positive result may indicate diffuse cutaneous systemic sclerosis, often linked to lung, kidney, or heart involvement. Doctors use this blood test to confirm diagnosis, evaluate unexplained symptoms such as skin thickening or joint pain, and guide monitoring and treatment of autoimmune connective tissue diseases.
The Jo-1 Antibody Test measures antibodies that target histidyl-tRNA synthetase, often associated with autoimmune myositis and interstitial lung disease. This marker helps reveal autoimmune-related muscle inflammation, chronic lung symptoms, and joint pain. Results provide insights into underlying immune activity, assisting providers in diagnosis, treatment planning, and ongoing disease management for connective tissue disorders.
The Myelin IgG Antibody Test detects antibodies targeting myelin, the protective sheath around nerves. Elevated levels may indicate autoimmune demyelinating disorders such as multiple sclerosis, neuromyelitis optica, or related inflammatory neuropathies. This test supports diagnosis, evaluation of neurological symptoms, and differentiation of demyelinating diseases that affect the central nervous system.
The Proteinase-3 Antibody Test detects antibodies against proteinase-3, a neutrophil enzyme associated with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. Elevated levels are strongly linked to granulomatosis with polyangiitis and other autoimmune small vessel vasculitides. This test aids in diagnosis, assessing disease activity, and guiding management of systemic inflammatory and autoimmune vascular conditions.
The Cytomegalovirus (CMV) IgM Antibody Test detects IgM antibodies, indicating a recent or active CMV infection. This blood test helps diagnose primary CMV, reactivation, or reinfection, especially important for pregnant women, transplant candidates, and immunocompromised patients. Used with CMV IgG testing, it helps distinguish new infections from past exposure for accurate clinical evaluation.
The Cytomegalovirus (CMV) IgG Antibody Test detects IgG antibodies to CMV, indicating past infection or immunity. This blood test helps determine prior exposure, assess immune status in pregnancy, transplant patients, or immunocompromised individuals, and guide risk evaluation. A positive result shows past CMV infection, while results are used with IgM testing to distinguish recent vs. past infection.
The Acetylcholine Receptor Binding Antibody Test detects antibodies targeting acetylcholine receptors, a hallmark of myasthenia gravis. This autoimmune disorder affects nerve-to-muscle communication, causing weakness and fatigue. The test helps confirm diagnosis, differentiate from other neuromuscular diseases, and guide treatment. Elevated antibody levels support early detection and ongoing management of myasthenia gravis.
The Thyroid Peroxidase Antibodies (TPOAb) Test detects antibodies that target thyroid peroxidase, an enzyme vital for thyroid hormone production. High levels often indicate autoimmune thyroid disorders such as Hashimoto’s thyroiditis or Graves’ disease. Doctors order this test to evaluate symptoms like fatigue, weight changes, hair loss, or irregular heartbeat and to confirm thyroid disease. It provides key insight into autoimmune activity and overall thyroid health.
The Toxoplasma IgG Antibody Test detects IgG antibodies to Toxoplasma gondii, the parasite that causes toxoplasmosis. A positive result indicates past infection or immunity, while rising levels may suggest recent exposure. Doctors use this blood test to evaluate immune status in pregnant women, immunocompromised patients, or those at risk for complications. Results help guide diagnosis, monitor infection history, and inform patient care planning.
The DNA (ds) Antibody Test detects double-stranded DNA antibodies, often linked to systemic lupus erythematosus (SLE) and other autoimmune diseases. High levels may indicate lupus activity, kidney involvement, or autoimmune flare-ups. Doctors order this test for patients with joint pain, fatigue, rash, or suspected connective tissue disease. Results provide critical insight for diagnosing lupus, monitoring disease progression, and guiding treatment decisions.
The Sm and Sm/RNP Antibodies Test detects autoantibodies associated with systemic lupus erythematosus (SLE) and mixed connective tissue disease (MCTD). Sm antibodies are highly specific for lupus, while Sm/RNP antibodies appear in MCTD and sometimes overlap syndromes. Physicians use this test to support diagnosis, evaluate autoimmune activity, and guide monitoring alongside other clinical findings and laboratory markers.
The Sjögren's SS-B Antibody Test measures antibodies targeting the SS-B/La antigen, aiding diagnosis of Sjögren’s syndrome and differentiating it from other autoimmune conditions. Detected most often with SS-A/Ro antibodies, SS-B positivity can guide clinicians in assessing disease activity, organ involvement, and systemic features. This test supports evaluation of patients with chronic dryness, fatigue, or suspected connective tissue disease.
The Platelet IgG IgM Antibodies Test detects antibodies directed against platelet surface antigens to help identify immune-mediated platelet destruction. Elevated platelet-associated IgG or IgM antibodies can indicate immune thrombocytopenia (ITP), drug-induced thrombocytopenia, or transfusion reactions. This test supports evaluation of unexplained low platelet counts and autoimmune hematologic disorders.
The SARS-CoV-2 IgG Antibody Test detects IgG antibodies that develop as an immune response to a prior COVID-19 infection. A positive result confirms past exposure but does not diagnose active illness or detect immunity from vaccination. Doctors use this blood test to evaluate unexplained symptoms, confirm prior infection, and track antibody persistence, providing useful insight into a patient’s history with coronavirus infection.
The Cytomegalovirus (CMV) IgG IgM Antibodies Test detects both recent and past infection with CMV, a common herpesvirus. IgM indicates recent or active infection, while IgG shows past exposure and possible immunity. Doctors order this test for pregnant women, immunocompromised patients, or those with unexplained fever or fatigue. Results help diagnose CMV, guide treatment, and assess risk of complications such as congenital infection or organ damage.
The Rubella IgM Antibody Test measures immune response to the rubella virus by identifying IgM antibodies produced soon after exposure. Detection of rubella IgM helps diagnose recent infection, assess rash-related illness, and monitor risk in pregnancy where congenital rubella syndrome may occur. This test provides valuable insight into acute infection, immunity status, and systemic health.
