Ulta Lab Tests

Cardio IQ Tests

Cardio IQ advanced lipid testing goes beyond a basic cholesterol panel to give a clearer picture of cardiovascular risk. These blood tests evaluate atherogenic particle number and type, genetically driven lipoproteins, and low-grade vascular inflammation—factors that standard LDL-C alone can miss.

Use Cardio IQ markers to refine screening, support a diagnostic work-up when risk seems higher than expected, and monitor response to lifestyle or therapy. Results help you and your clinician see whether particle burden (ApoB/LDL-P), lipoprotein(a), or inflammation is adding risk. Advanced testing improves risk stratification, but it does not diagnose heart disease or replace imaging (e.g., coronary calcium) when indicated.

Signs, Situations & Related Needs

  • Borderline or discordant results: LDL-C looks “okay” but strong family history or other risks suggest more testing.

  • Premature ASCVD in family: early heart attack, stroke, or calcific aortic valve disease in relatives.

  • High triglycerides / metabolic syndrome / diabetes: need particle-based risk detail beyond LDL-C.

  • Statin intolerance or limited response: refine the plan with particle number and Lp(a).

  • Suspected familial hypercholesterolemia (FH): very high LDL-C or tendon xanthomas.

  • Athlete or prevention-focused: want a more granular baseline to track over time.
    Seek urgent care for chest pain, severe shortness of breath, fainting, or stroke-like symptoms.

Why These Tests Matter

What testing can do

  • Risk refine: quantify atherogenic particles (ApoB/LDL-P), detect genetic Lp(a) elevation, and assess inflammation (hs-CRP, Lp-PLA2) to sharpen risk estimates.

  • Guide follow-up: when standard lipids are borderline or discordant with personal/family risk, advanced markers can guide intensity of lifestyle or therapy.

  • Track trends: follow changes after nutrition, activity, weight management, or medication adjustments.

What testing cannot do

  • Confirm or rule out blocked arteries or active heart disease.

  • Replace guideline-directed assessments (blood pressure, diabetes screening, ASCVD risk tools) or imaging when appropriate.

  • Predict events with certainty; results must be interpreted with your clinician.

What These Tests Measure (at a glance)

  • Apolipoprotein B (ApoB): counts all atherogenic particles (VLDL remnants, IDL, LDL, Lp(a)); often superior to LDL-C when triglycerides are high or results are discordant.

  • LDL Particle Number/Size (LDL-P, subfractions): particle burden and distribution (small/dense vs. larger particles) that may add risk context.

  • Lipoprotein(a) [Lp(a)]: genetically determined, mostly lifelong; adds risk for ASCVD and calcific aortic valve disease regardless of LDL-C. Not meaningfully changed by routine lifestyle measures.

  • Apolipoprotein A-I (ApoA-I) & HDL subfractions: context for HDL functionality; best interpreted with ApoB (ApoB/ApoA-I ratio).

  • Remnant cholesterol (RLP-C): cholesterol in triglyceride-rich remnants that may promote atherogenesis.

  • High-sensitivity C-reactive protein (hs-CRP): systemic low-grade inflammation associated with higher cardiovascular risk; trend over time.

  • Lp-PLA2 (activity or mass): enzyme linked to vascular inflammation; use alongside other risk markers.

  • Standard lipids (TC, LDL-C, HDL-C, TG) & Non-HDL-C: remain core measures and are included in many advanced panels.

Who Benefits & When to Consider Cardio IQ

Scenario Useful markers Why it helps
Family history of premature ASCVD Lp(a), ApoB, LDL-P Detect inherited contributors beyond LDL-C
Diabetes/metabolic syndrome, high TG ApoB, LDL-P, RLP-C, hs-CRP Clarify particle burden and residual risk
LDL-C “normal” but risk seems high ApoB, Lp(a), hs-CRP Uncover discordance and inflammatory risk
Statin intolerance/partial response ApoB, LDL-P, Lp(a) Gauge residual atherogenic particles
Suspected FH ApoB, LDL-P, Lp(a) Strengthen evidence for intensive management

How the Testing Process Works

  1. Choose your starting set: many begin with ApoB + Lp(a) added to a standard lipid panel; consider LDL-P/subfractions and hs-CRP.

  2. Prepare for accuracy: follow any fasting instructions; avoid intense exercise and heavy alcohol the day before; keep supplements consistent unless your order says to hold (biotin can affect some assays).

  3. Get your draw: simple blood test at a local patient service center; results post securely in your account.

  4. Review with your clinician: combine advanced markers with age, BP, diabetes status, smoking, family history, and (if available) coronary calcium.

  5. Set a tracking cadence: recheck at intervals your clinician recommends, especially after lifestyle or therapy changes.

Interpreting Results (General Guidance)

  • ApoB / LDL-P: higher values indicate more atherogenic particles; particularly informative when triglycerides are elevated or LDL-C seems “fine” but risk is high.

  • Lp(a): largely genetic and stable; a high result signals added lifetime risk and often prompts more aggressive risk-factor management.

  • hs-CRP: interpret trends; levels can rise temporarily with infection, injury, or hard training.

  • Subfractions/size: treat as contextual—particle number (ApoB/LDL-P) usually carries the most weight.
    Always interpret results with a qualified healthcare professional; do not start or stop medications without medical guidance.

Choosing Panels vs. Individual Tests

  • Quick risk refinement: Standard Lipid Panel + ApoB + Lp(a)

  • Metabolic/discordant profile: Add LDL-P/subfractions, RLP-C, hs-CRP

  • Inflammation focus: hs-CRP ± Lp-PLA2 for vascular-inflammation context

  • Therapy follow-up: Recheck ApoB (and LDL-P if tracked) to confirm particle reduction

FAQs

Do I need to fast?
Follow your order. Some advanced lipid panels prefer fasting; ask if you’re unsure.

Is Lp(a) something I can lower with diet?
Lp(a) is genetically determined and usually stable. Lifestyle is still key for overall risk; discuss options with your clinician.

Which is more important—LDL-C or ApoB?
They often align, but ApoB directly reflects particle number and may be more informative when triglycerides are high or results seem discordant.

Can exercise raise hs-CRP?
Yes—hard sessions and acute illness can temporarily elevate hs-CRP. Test on a recovery day when possible.

How often should I repeat Cardio IQ markers?
Commonly every 3–6 months after changes, then less often once stable—timing is individualized.

Are these tests a substitute for heart imaging?
No. They refine risk; imaging (e.g., coronary calcium) and guideline care still matter.

Related Categories & Key Tests

  • Upward: Heart & Cardiovascular Tests Hub

  • Sideways: Lipid Tests • Cardiometabolic Health • Inflammation (hs-CRP) • Diabetes & Insulin Resistance • Genetic Heart Risk

  • Key Tests (downward): Apolipoprotein B (ApoB) • Lipoprotein(a) [Lp(a)] • LDL Particle Number/Size (subfractions) • Remnant Cholesterol (RLP-C) • Apolipoprotein A-I • hs-CRP • Lp-PLA2 • Standard Lipid Panel

References

  • American College of Cardiology/American Heart Association — Cholesterol management and risk assessment guidelines.
  • National Lipid Association — Scientific statements on ApoB, Lp(a), and remnant cholesterol.
  • European Atherosclerosis Society — Consensus on Lp(a) and atherogenic lipoproteins.
  • AHA/CDC — Inflammation markers and cardiovascular risk guidance.
  • Clinical reviews on LDL particle metrics and residual risk.

Available Tests & Panels

Your Cardio IQ Tests menu is pre-populated in the Ulta Lab Tests system. Start by adding ApoB and Lp(a) to a standard lipid panel, then include LDL-P/subfractions, RLP-C, hs-CRP, or Lp-PLA2 as needed. Schedule a draw (fasting if instructed) and review results with your clinician to personalize prevention and follow-up.

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The Cardio IQ™ NT-proBNP Test evaluates levels of NT-proBNP in blood to help assess heart function and cardiovascular stress. High concentrations are associated with heart failure, left ventricular dysfunction, and fluid imbalance. This test provides insight into cardiac performance, systemic health, and conditions such as hypertension or other disorders that impact cardiovascular risk.

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Blood Draw
Also Known As: Brain Natriuretic Peptide Test, proBNP test,
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The Cardio IQ™ Triglycerides Test measures triglyceride levels in the blood, an important marker of lipid metabolism and cardiovascular health. Elevated triglycerides are linked to increased risk of heart disease, pancreatitis, and metabolic syndrome. Physicians use this test to assess risk factors, monitor therapy response, and guide lifestyle or treatment decisions, often as part of a broader lipid or heart health evaluation.

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The Cardio IQ Vitamin D test, also known as a 25-hydroxy vitamin D test, measures the levels of total vitamin D in the blood, including both vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). It provides information about an individual's overall vitamin D status.

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Blood Draw
Also Known As: Ergocalciferol Test, Vitamin D2 Test, Cholecalciferol Test, Vitamin D3 Test, Calcidiol Test, 25-hydroxyvitamin D Test, Calcifidiol Test, 25-hydroxy-vitamin D Test
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The Cardio IQ™ Diabetes and ASCVD Risk Panel with Scores measures advanced cardiovascular and metabolic markers to evaluate risk for atherosclerotic cardiovascular disease and type 2 diabetes. This panel includes lipid analysis, glucose-related biomarkers, and inflammation indicators, helping assess cardiometabolic health. Results provide clinicians with detailed scoring to identify patterns that may influence prevention and long-term disease management.

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The Cardio IQ™ Advanced Lipid Panel Test provides a detailed assessment of cardiovascular risk by measuring total cholesterol, HDL, LDL, triglycerides, ApoB, Lipoprotein (a), and non-HDL cholesterol. It also analyzes particle number, size, and patterns of LDL and HDL, offering deeper insights into lipid metabolism and heart disease risk beyond standard cholesterol testing.

Also Known As: Advanced Lipid Profile Test, Advanced Cholesterol Panel Test, Advanced Lipids Blood Test 
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The Omega-3 and Omega-6 Fatty Acids Test measures essential fatty acids, including EPA, DHA, and arachidonic acid, to assess balance between omega-3 and omega-6 in the blood. This ratio is linked to heart health, inflammation, brain function, and metabolic wellness. Doctors use this test to evaluate diet quality, detect deficiencies or excess, and guide nutrition or supplement plans that support cardiovascular, cognitive, and overall long-term health.

Also Known As: OmegaCheck® Test
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What Is Cardio IQ Testing?

Did you know that almost half of all American adults have some form of cardiovascular ailment?

A report was published in 2019 by the Journal of the American Heart Association.

In the 2019 report, it was revealed that 121.1 million adults in America (48% of the 2019 numbers) have cardiovascular ailments.

With this being the case, it makes sense to take the necessary precautions to protect your health.

And one of the best ways to do that is by having your blood tested with cardio IQ testing.

If you're interested in learning more about cardio IQ lab tests to evaluate the health of your cardiovascular system, keep reading.

We will provide you with an overview of the available tests to help you know about your heart and provide insights into your health.

What Is Cardio IQ Testing?

Cardio IQ testing is essentially a testing procedure used to assess the LDL particles in your body to measure the likelihood of heart disease. Clinicians then use this detailed data to create a more efficient and customized treatment for patients.

Furthermore, this type of blood test makes diagnostics much more accurate and precise than they would have been otherwise.

Think of this kind of testing as an overview -- the big picture, if you will -- of the condition of your overall cardiovascular health and wellbeing.

It can both save and extend your life by finding indicators of certain ailments (heart disease, high blood pressure, high cholesterol, etc.).

The Benefits of Cardio IQ Testing Lab Testing

A cardio IQ advanced lipid panel test can provide many advantages. You could benefit from one immensely as it offers a more detailed analysis of your working cardiovascular system.

This will give way to greater protection against any potential cardiovascular diseases (CVD) that you may currently be unaware of. 

The importance of this cannot be understated. Every year, heart disease takes the lives of about 8 times the number of women who have breast cancer and 15 times the number of men who have prostate cancer.

In addition to that, a new study uncovered an interesting finding.

Almost 75% of people who were emitted to the hospital following a heart attack displayed no signs of being at risk for one.

Blood tests can help with avoiding such events from happening before it's too late. Then adjustments to lifestyle can be made preemptively to prevent such occurrences from taking place.

But that's not all a cardio IQ test can help you prevent. Here are a few more examples of avoidances to keep in mind:

  • High blood pressure
  • Metabolic syndrome
  • Cardiometabolic risk
  • Low HDL (high-density lipoproteins)
  • High triglycerides
  • Diabetes

It's suggested that you should try fasting for 9 to 12 hours before having your blood drawn.

The cardio IQ test record will reveal a detailed assessment of any cardiovascular dangers. This is what will enable physicians to do a better job with their diagnostics.

Physicians can be more accurate with their suggestions. And as a result, prescribe the perfect treatments and proper resources to help you reduce any budding cardiovascular ailments.

Cardio IQ Tests

There are a group of important Cardio IQ blood tests to select from -- each with its specific value to identify the health of your cardiovascular system.

Here is a list of the Cardio IQ tests you should consider:

Cardio IQ Lipid Panel

This is undoubtedly the most common and repeated Lipid Panel. Elements include the factors useful in the detection of patients who have hyperlipidemia.

Cardio IQ Lipoprotein (A)

Higher amounts of LPA are connected with the enhanced danger of coronary heart disease.

Cardio IQ Lipoprotein Fractionation, Ion Mobility

There seems to be a strong connection between a heightened danger of untimely heart disease with a reduced amount of low-density lipoprotein particles. Ion Mobility provides a direct assessment of LDL particle size.

Cardio IQ Apolipoprotein A-1

Apolipoprotein A1 is the main protein connected with high-density lipoproteins (HDL). Similar to HDL cholesterol, enhanced concentrations are connected with lower dangers of cardiovascular ailments.

Cardio IQ Apolipoprotein B

As it pertains to Apolipoprotein B, two main forms can be found, B-48 and B-100. B-100, arranged and manufactured in the liver, is the main protein of very low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), as well as low-density lipoprotein cholesterol.

Cardio IQ Apolipoprotein Evaluation

The primary protein that is associated with HDL cholesterol is Apolipoprotein A1. The dominant protein connected with lipid particles as well as HDL cholesterol is Apolipoprotein B-100.

The percentages of the two apolipoproteins connect with the danger of cardiovascular ailments.

Cardio IQ Cholesterol, Total

Total serum cholesterol examination is handy in the prognosis of hyperlipoproteinemia, thyroid ailments, etc.

Cardio IQ Direct LDL

Low-density lipoprotein cholesterol is known as "bad" cholesterol. Different ranges of its risk are based on the guidelines that are supplied by the NCEP (National Cholesterol Education Program).

Cardio IQ Fibrinogen Antigen, Nephelometry

Lower amounts of fibrinogen are associated with bleeding, commonly second to liver disease or DIC (Disseminated Intravascular Coagulation).

Cardio IQ HDL Cholesterol

High-density lipoprotein cholesterol ("good cholesterol") correlates to the danger of cardiovascular diseases. It elevates with regular exercise, medium alcohol intake, and with oral estrogen treatment.

Lowered levels occur with obesity, distress, as well as the smoking of cigarettes and diabetes.

Cardio IQ Hemoglobin A1c

To help with blood glucose regulation, the ADA (American Diabetes Association) has suggested hemoglobin A1c testing (HbA1c) two times annually for those who suffer from glycemia and then quarterly for those with bad glucose levels.

Cardio IQ Homocysteine

A higher amount of homocysteine is an unhampered factor in cardiovascular ailments.

Cardio IQ hs-CRP

The Cardio IQ hs-CRP test is very accurate in foreseeing the risks and potential of cardiovascular ailments.

Cardio IQ Insulin

This insulin test is used to identify hyperinsulinemia in individuals. The effects of hyperinsulinemia might be due to a tumor producing insulin (insulinoma), a syndrome caused by insulin resistance.

Cardio IQ CYP2C19 Genotype

Genotype tests can discover different variations in the CYP2C19 gene in the segment of DNA, leading to changed enzyme acts. Additionally, it may need other treatments or an amount of medication to achieve therapeutic levels.

Cardio IQ 4q25-AF Risk Genotype

This is a test that will assist physicians in measuring the risk for AFib (atrial fibrillation) and stroke. As many as 8 cardiovascular-connected genetic tests can be done on a single person.

Cardio IQ 9p21 Genotype

This is a test that will help measure risk connected with MI (Myocardial Infarction). It will be especially effective in males below the age of 50 and females below the age of 60.

Cardio IQ ApoE Genotype

This test is used to determine isotypes of ApoE, which will assist with the measurement of CHD (Coronary Herat Disease) as well as hyperlipoproteinemia.

Cardio IQ KIF6 Genotype

This is a test that will find and uncover variants of genes connected with an enhanced danger of CHD (Coronary Heart Disease).

Frequently Asked Questions About Cardio IQ Testing

When it comes to a complex subject such as cardio IQ testing, no matter how much we cover, there will be questions left unanswered. So here are a few frequently asked questions that you may have:

What Exactly Is a Cardio Test Panel?

The test panel is important because it works to assess a multitude of markers as well as lipid subfractions. This can be helpful for finding ailments sooner and more efficiently.

It helps to provide a broader and more complete assessment of dyslipidemia as well as a cardiovascular risk than the traditional lipid panel provides.

Why Is the Test Panel so Important?

The test panel assesses the quality level of a person's lipid markers as well as apolipoprotein B, in addition to the lipoprotein particle numbers and sizes.

This then makes it much easier to provide a more detailed measurement of the general cardiac risk.

Does It Take a Long Time to Receive the Results?

It can take around 1 to 2 business days to receive the results of Cardio IQ tests.

Benefits of CARDIO IQ Lab Testing With Ulta Lab Tests

Ulta Lab Tests offers highly accurate and reliable tests so that you can make informed decisions about your health. Here are a few great things to love about Ulta Lab Tests:

  • You'll get secure and confidential results.
  • You don't need health insurance.
  • You don't need a physician's referral
  • You'll get affordable pricing
  • We offer a 100% satisfaction guarantee

Are You Ready for Your Cardio IQ Test?

Order your Cardio IQ lab test today, and your results will be provided to you securely and confidentially online