Comprehensive Cardiovascular Risk Assessment Panel

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.



Also known as: Apolipoprotein A-1, Apolipoprotein A1 Cardio IQ, Cardio IQ Apolipoprotein A-1

Apolipoprotein A1

Also known as: Apolipoprotein B Cardio IQ, Cardio IQ Apolipoprotein B

Apolipoprotein B



Also known as: Cardio IQ hs-CRP , hsCRP Cardio IQ

Hs Crp

A high-sensitivity CRP (hs-CRP) test may be used by itself, in combination with other cardiac risk markers, or in combination with a lipoprotein-associated phospholipase A2 (Lp-PLA2) test that evaluates vascular inflammation. The hs-CRP test accurately detects low concentrations of C-reactive protein to help predict a healthy person's risk of cardiovascular disease (CVD). High-sensitivity CRP is promoted by some as a test for determining a person's risk level for CVD, heart attacks, and strokes. The current thinking is that hs-CRP can play a role in the evaluation process before a person develops one of these health problems.

Also known as: Cardio IQ Lipid Panel, Lipid Panel Cardio IQ, Lipids

Chol/HDLC Ratio

Cholesterol, Total

Cholesterol is a waxy, fat-like substance that occurs naturally in all parts of the body. Your body needs some cholesterol to work properly. But if you have too much in your blood, it can combine with other substances in the blood and stick to the walls of your arteries. This is called plaque. Plaque can narrow your arteries or even block them. High levels of cholesterol in the blood can increase your risk of heart disease. Your cholesterol levels tend to rise as you get older. There are usually no signs or symptoms that you have high blood cholesterol, but it can be detected with a blood test. You are likely to have high cholesterol if members of your family have it, if you are overweight or if you eat a lot of fatty foods. You can lower your cholesterol by exercising more and eating more fruits and vegetables. You also may need to take medicine to lower your cholesterol.

HDL Cholesterol


Non HDL Cholesterol


Triglycerides are a form of fat and a major source of energy for the body. This test measures the amount of triglycerides in the blood. Most triglycerides are found in fat (adipose) tissue, but some triglycerides circulate in the blood to provide fuel for muscles to work. After a person eats, an increased level of triglycerides is found in the blood as the body converts the energy not needed right away into fat. Triglycerides move via the blood from the gut to adipose tissue for storage. In between meals, triglycerides are released from fat tissue to be used as an energy source for the body. Most triglycerides are carried in the blood by lipoproteins called very low density lipoproteins (VLDL). High levels of triglycerides in the blood are associated with an increased risk of developing cardiovascular disease (CVD), although the reason for this is not well understood. Certain factors can contribute to high triglyceride levels and to risk of CVD, including lack of exercise, being overweight, smoking cigarettes, consuming excess alcohol, and medical conditions such as diabetes and kidney disease.

Also known as: Cardio IQ Lipoprotein (a), Lipoprotein a Cardio IQ

Lipoprotein (A)

Lipoprotein-a, or Lp(a) are molecules made of proteins and fat. They carry cholesterol and similar substances through the blood. A high level of Lp(a) is considered a risk factor for heart disease. High levels of lipoproteins can increase the risk of heart disease. The test is done to check your risk of atherosclerosis, stroke, and heart attack.

Also known as: Ion Mobility, Cardio IQ Lipoprotein Fractionation, Ion Mobility , HDL Subfractions, IDL Subfractions, LDL Subfractions, Lipoprotein Fraction, Lipoprotein Fractionation, Lipoprotein Fractionation Ion Mobility Cardio IQ, Quest Diagnostics has replaced the VAP® Cholesterol Test with Lipoprotein Fractionation, Ion Mobility, Cardio IQ™ test

HDL Large

LDL Medium

LDL Particle Number

LDL Pattern

LDL Peak Size

LDL Small













*Important Information on Lab Test Processing Times: Ulta Lab Tests is committed to informing you about the processing times for your lab tests processed through Quest Diagnostics. Please note that the estimated processing time for each test, indicated in business days, is based on data from the past 30 days across the 13 Quest Diagnostics laboratories for each test. These estimates are intended to serve as a guide and are not guarantees. Factors such as laboratory workload, weather conditions, holidays, and the need for additional testing or maintenance can influence actual processing times. We aim to offer estimates to help you plan accordingly. Please understand that these times may vary, and processing times are not guaranteed. Thank you for choosing Ulta Lab Tests for your laboratory needs.

The Comprehensive Cardiovascular Risk Assessment Panel panel contains 12 tests with 32 biomarkers.

The Comprehensive Cardiovascular Risk Assessment Panel is a meticulously curated set of diagnostic tests designed to provide an in-depth analysis of an individual's risk for cardiovascular disease (CVD).

This panel goes beyond the traditional lipid profile to include advanced biomarkers for endothelial dysfunction, lipid particle size and concentration, inflammation, and genetic predisposition to atherosclerosis. With markers such as ADMA/SDMA, various apolipoproteins, hs-CRP, and more, this panel offers a multifaceted approach to understanding the complex interplay between different physiological factors that contribute to cardiovascular health.

By integrating these diverse measures, healthcare providers can develop more personalized and effective strategies for preventing and managing heart disease, offering patients a comprehensive overview of their cardiovascular risk profile.

Test Descriptions and Values:

  1. ADMA/SDMA: These are markers of endothelial dysfunction, which is an early sign of cardiovascular disease (CVD). Elevated levels of ADMA (asymmetric dimethylarginine) and SDMA (symmetric dimethylarginine) can inhibit nitric oxide production, leading to impaired vasodilation and increased risk of atherosclerosis.

  2. Apolipoprotein A-1, Cardio IQ™: This is the major protein component of high-density lipoprotein (HDL) in plasma. Higher levels are protective against CVD as Apo A-1 helps to clear cholesterol from cells and atheromas.

  3. Apolipoprotein B, Cardio IQ™: This is the main component of low-density lipoprotein (LDL) and is a better indicator than LDL cholesterol alone in assessing cardiovascular risk as it reflects the number of atherogenic particles.

  4. CARDIO IQ(R) Lp-PLA2 Activity: Lipoprotein-associated phospholipase A2 (Lp-PLA2) is an enzyme involved in the inflammation of blood vessels and is a risk factor for CVD, especially in predicting risk of stroke and coronary heart disease.

  5. CARDIO IQ(R) Myeloperoxidase (MPO): MPO is an enzyme released by white blood cells during inflammation. Elevated levels can indicate vascular inflammation and increased risk of CVD.

  6. hs-CRP, Cardio IQ™: High-sensitivity C-reactive protein is a marker of inflammation and is associated with higher risk of heart attacks and strokes. It can predict the occurrence of cardiovascular events in individuals with no apparent CVD.

  7. Lipid Panel, Cardio IQ™: This includes measurement of total cholesterol, HDL cholesterol, LDL cholesterol, and triglycerides. These levels are directly implicated in cardiovascular health.

  8. Lipoprotein (a), Cardio IQ™: Lp(a) is a particle that carries cholesterol and has pro-inflammatory and pro-thrombotic properties. Elevated Lp(a) levels are a genetic risk factor for atherosclerotic diseases.

  9. Lipoprotein Fractionation, Ion Mobility, Cardio IQ™: This test provides detailed information about the size and density of lipoprotein particles. Small, dense LDL particles are more atherogenic than larger, buoyant ones.

  10. Omega-3 and -6 Fatty Acids, Plasma: These fatty acid levels are indicative of dietary intake and can influence inflammatory processes and cell membrane function, which have roles in CVD risk.

  11. OxLDL: Oxidized LDL is a form of LDL cholesterol that has been modified by oxidation. It is thought to be more atherogenic and is involved in the development of atherosclerosis.

  12. TMAO (Trimethylamine N-Oxide): TMAO is a metabolite associated with gut microbiota that has been implicated in promoting atherosclerosis and is linked to increased risk for CVD events.

This panel gives a detailed picture of an individual's risk for cardiovascular disease, focusing on cholesterol particles, inflammation, and genetic predisposition, allowing for targeted risk management strategies.

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