Pain Management

Drug Monitoring, Base Panel, Screen, Urine

Clinical Significance
Drug Monitoring, Base Panel, Screen, Urine - The test is a screening assay using a homogeneous enzyme immunoassay method of analysis. Therapeutic urine drug monitoring is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Urine drug test results equal to or greater than cutoff are reported as positive and results less than cutoff are reported as negative.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
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Benzodiazepines, Cocaine Metabolite, Opiates, Oxycodone
Specimen validity consisting of Creatinine, Oxidant, and pH testing.

Alternative Name(s)
Prescription Drug Monitoring,Pain Management

Drug Monitoring, Panel 1, Screen, Urine

Clinical Significance
Drug Monitoring, Panel 1, Screen, Urine - The test is a screening assay using a homogeneous enzyme immunoassay method of analysis. Therapeutic urine drug monitoring is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Urine drug test results equal to or greater than cutoff are reported as positive and results less than cutoff are reported as negative.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
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Amphetamines, Barbiturates, Benzodiazepines, Marijuana Metabolite, Cocaine Metabolite, Methadone Metabolite, Opiates, Oxycodone, Phencyclidine
Specimen validity consisting of Creatinine, Oxidant, and pH testing.

Alternative Name(s)
Prescription Drug Monitoring,Pain Management

Drug Monitoring, Panel 3, Screen, Urine

Clinical Significance
Drug Monitoring, Panel 3, Screen, Urine - The test is a screening assay using a homogeneous enzyme immunoassay method of analysis. Therapeutic urine drug monitoring is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Urine drug test results equal to or greater than cutoff are reported as positive and results less than cutoff are reported as negative.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
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Amphetamines, Benzodiazepines, Marijuana Metabolite, Cocaine Metabolite, Opiates, Oxycodone
Specimen validity consisting of Creatinine, Oxidant, and pH testing.

Alternative Name(s)
Prescription Drug Monitoring,Pain Management

Drug Monitoring, Panel 4, Screen, Urine

Clinical Significance
Drug Monitoring, Panel 4, Screen, Urine - The test is a screening assay using a homogeneous enzyme immunoassay method of analysis. Therapeutic urine drug monitoring is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Urine drug test results equal to or greater than cutoff are reported as positive and results less than cutoff are reported as negative.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
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Amphetamines, Barbiturates, Benzodiazepines, Cocaine Metabolite, Methadone Metabolite, Opiates, Oxycodone, Phencyclidine
Specimen validity consisting of Creatinine, Oxidant, and pH testing.

Alternative Name(s)
Prescription Drug Monitoring,Pain Management

Drug Monitoring, Panel 5, Screen, Urine

Clinical Significance
Drug Monitoring, Panel 5, Screen, Urine - The test is a screening assay using a homogeneous enzyme immunoassay method of analysis. Therapeutic urine drug monitoring is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Urine drug test results equal to or greater than cutoff are reported as positive and results less than cutoff are reported as negative.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
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Amphetamines, Barbiturates, Benzodiazepines, Marijuana Metabolite, Cocaine Metabolite, Methadone Metabolite, Opiates, Oxycodone
Specimen validity consisting of Creatinine, Oxidant, and pH testing.

Alternative Name(s)
Prescription Drug Monitoring,Pain Management

Quest Drug Monitoring medMATCH® Report

Clinical Significance
Prescribed Drugs, MedMATCH® Drug Monitoring Report - medMATCH reports are simple and intuitive, and designed to provide actionable insights with the goal of easy, “at-a-glance” interpretation.
The reports provide a summary of your patient’s consistent and inconsistent results for prescribed drugs, and also include reporting on nonprescribed, inconsistent drugs. This allows you to have a better view of drugs that your patient is taking, address any noncompliance issues, and be alerted to any potential drug misuse or dangerous drug combinations.

Includes
Test code 39158 will need to be ordered if medMATCH is requested. It should be ordered once per accession with the additional Drug Monitoring codes. When ordered, all Drug Monitoring order codes on the accession will be treated as medMATCH. There will no longer be a non-medMATCH and medMATCH version of Drug Monitoring order codes.

Drug Monitoring, Alcohol Metabolite, Quantitative, Urine

Clinical Significance
Drug Monitoring, Alcohol Metabolite, Quantitative, Urine - Ethyl glucuronide (EtG) and ethyl sulfate (EtS) are minor metabolite of ethanol metabolites and excreted in urine for a longer time than ethanol. Positive EtG and/or EtS test results thus provide a strong indication that the person has recently consumed alcohol, even when ethanol is no longer detectable. The test is a definitive assay using liquid chromatography mass spectroscopy (LC/MS/MS) methodology. Therapeutic urine drug monitoring of these metabolites is important for ensuring compliance to treatment strategies. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
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Ethyl Glucuronide (EtG) and Ethyl Sulfate (EtS)

Reference Range(s)
Ethyl Glucuronide (ETG)    <500 ng/mL
Ethyl Sulfate (ETS)    <100 ng/mL

Alternative Name(s)
Prescription Drug Monitoring,Pain Management

Drug Monitoring, Panel 1, with Confirmation, Urine

Clinical Significance
Drug Monitoring, Panel 1, with Confirmation, Urine - The test is a screening assay using a homogeneous enzyme immunoassay method of analysis. Presumptive positive screen results are reflexed to a more specific and sensitive liquid chromatography mass spectroscopy (LC/MS/MS) test. Therapeutic urine drug monitoring is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Urine drug test results equal to or greater than cutoff are reported as positive and results less than cutoff are reported as negative. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine.

Includes

• If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH. 
•  
• If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d. 
• .
• Initial screen of Amphetamines, Barbiturates, Benzodiazepines, Marijuana Metabolite, Cocaine Metabolite, Methadone Metabolite, Opiates, Oxycodone, Phencyclidine drug classes. Specimen validity consisting of Creatinine, Oxidant, and pH testing. 
• If screen of drug class is positive, a confirmation of the drug class will be performed at an additional charge (CPT code(s): dependent upon the confirmed drug class). 
• Confirmation includes the following analytes within their associated drug class: 
• Amphetamines: Amphetamine, Methamphetamine 
• Barbiturates: Amobarbital, Butalbital, Pentobarbital, Phenobarbital, Secobarbital 
• Benzodiazepines: Alphahydroxyalprazolam, Alphahydroxymidazolam, Alphahydroxytriazolam, Aminoclonazepam, Hydroxyethylflurazepam, Lorazepam, Nordiazepam, Oxazepam, Temazepam 
• Marijuana Metabolite: Marijuana Metabolite 
• Cocaine Metabolite: Benzoylecgonine 
• Methadone Metabolite: EDDP, Methadone 
• Opiates: Codeine, Hydrocodone, Hydromorphone, Morphine, Norhydrocodone 
• Oxycodone: Noroxycodone, Oxycodone, Oxymorphone 
• Phencyclidine: Phencyclidine

Reference Range(s)
See Laboratory Report

Alternative Name(s)
Prescription Drug Monitoring, Pain Management

Drug Monitoring, Panel 6 with Confirmation, Urine

Clinical Significance
Drug Monitoring, Panel 6 with Confirmation, Urine - The test is a screening assay using a homogeneous enzyme immunoassay method of analysis. Presumptive positive screen results are reflexed to a more specific and sensitive liquid chromatography mass spectroscopy (LC/MS/MS) test. Therapeutic urine drug monitoring is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Urine drug test results equal to or greater than cutoff are reported as positive and results less than cutoff are reported as negative. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
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Initial screen of 6-Acetylmorphine, Alcohol Metabolites, Amphetamines, Barbiturates, Benzodiazepines, Marijuana Metabolite, Cocaine Metabolite, Methadone Metabolite, Opiates, Oxycodone, Phencyclidine drug classes. Specimen validity consisting of Creatinine, Oxidant, and pH testing.
If screen of drug class is positive, a confirmation of the drug class will be performed at an additional charge (CPT code(s): dependent upon the confirmed drug class).

Confirmation includes the following analytes within their associated drug class:

• 6-Acetylmorphine: 6-Acetylmorphine
• Alcohol Metabolites: Ethyl Glucuronide (ETG), Ethyl Sulfate (ETS)
• Amphetamines: Amphetamine, Methamphetamine
• Barbiturates: Amobarbital, Butalbital, Pentobarbital, Phenobarbital, Secobarbital
• Benzodiazepines: Alphahydroxyalprazolam, Alphahydroxymidazolam, Alphahydroxytriazolam, Aminoclonazepam, Hydroxyethylflurazepam, Lorazepam, Nordiazepam, Oxazepam, Temazepam
• Marijuana Metabolite: Marijuana Metabolite
• Cocaine Metabolite: Benzoylecgonine
• Methadone Metabolite: EDDP, Methadone
• Opiates: Codeine, Hydrocodone, Hydromorphone, Morphine, Norhydrocodone
• Oxycodone: Noroxycodone, Oxycodone, Oxymorphone
• Phencyclidine: Phencyclidine

Methodology
Screen: Immunoassay (IA) • Confirmation: Mass Spectrometry (MS)

Reference Range(s)
See Laboratory Report

Alternative Name(s)
Prescription Drug Monitoring,Pain Management

Drug Monitoring, Alcohol Metabolite, with Confirmation, Urine

Clinical Significance
Drug Monitoring, Alcohol Metabolite, with Confirmation, Urine - Ethyl glucuronide and ethyl sulfate are metabolites of ethanol (alcohol) that may be present in urine after ingestion of, or exposure to, drinks, foods, medication or other products containing ethyl alcohol. Incidental exposure to alcohol-containing products such as mouthwash or hand sanitizer have also been shown to produce positive alcohol metabolites test results. LC-MS/MS testing detects EtG and EtS regardless of the source. Therefore, we encourage you to interpret alcohol metabolite test results in light of the clinical picture.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
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Initial screen of the Alcohol Metabolites drug class. If screen is positive, a confirmation will be performed at an additional charge (CPT code(s): 80321 HCPCS: G0480).
Confirmation includes the following analytes: Ethyl Glucuronide (ETG), Ethyl Sulfate (ETS)

Reference Range(s)
Alcohol Metabolites    <500 ng/mL
  Ethyl Glucuronide (EtG)    <500 ng/mL
  Ethyl Sulfate (EtS)    <100 ng/mL

Alternative Name(s)
Prescription Drug Monitoring,Pain Management

Drug Monitoring, Amphetamines, Quantitative, Urine

Clinical Significance
Drug Monitoring, Amphetamines, Quantitative, Urine - The amphetamine class of drugs are traditionally classified as stimulants. Some members of the class (amphetamine) are prescribed for treatment of attention-deficit hyperactivity disorder (ADHD), to suppress appetite, and for narcolepsy. Other members of the class are considered drugs of abuse (methamphetamine, MDMA) with no accepted medical uses. The test is a definitive assay using liquid chromatography mass spectroscopy (LC/MS/MS) methodology. Therapeutic urine drug monitoring of the amphetamines and their metabolites is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
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Amphetamine and Methamphetamines

Reference Range(s)
Amphetamine    <250 ng/mL
Methamphetamines    <250 ng/mL

Alternative Name(s)
Prescription Drug Monitoring,Pain Management

Drug Monitoring, Amphetamines, Screen, Urine

Clinical Significance
Drug Monitoring, Amphetamines, Screen, Urine - The amphetamine class of drugs are traditionally classified as stimulants. Some members of the class (amphetamine) are prescribed for treatment of attention-deficit hyperactivity disorder (ADHD), to suppress appetite, and for narcolepsy. Other members of the class are considered drugs of abuse (methamphetamine, MDMA) with no accepted medical uses. The test is a screening assay using a homogeneous enzyme immunoassay method of analysis. Therapeutic urine drug monitoring of the amphetamines and their metabolites is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Urine drug test results equal to or greater than cutoff are reported as positive and results less than cutoff are reported as negative.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.

Reference Range(s)
Amphetamines    <500 ng/mL

Alternative Name(s)
Prescription Drug Monitoring,Pain Management

Drug Monitoring, Amphetamines, with Confirmation, Urine

Clinical Significance
Drug Monitoring, Amphetamines, with Confirmation, Urine - The amphetamine class of drugs are traditionally classified as stimulants. Some members of the class (amphetamine) are prescribed for treatment of attention-deficit hyperactivity disorder (ADHD), to suppress appetite, and for narcolepsy. Other members of the class are considered drugs of abuse (methamphetamine, MDMA) with no accepted medical uses. The test is a screening assay using a homogeneous enzyme immunoassay method of analysis. Presumptive positive screen results are reflexed to a more specific and sensitive liquid chromatography mass spectroscopy (LC/MS/MS) test. Therapeutic urine drug monitoring of the amphetamines and their metabolites is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Urine drug test results equal to or greater than cutoff are reported as positive and results less than cutoff are reported as negative. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
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Initial screen of the Amphetamines drug class. If screen is positive, a confirmation will be performed at an additional charge (CPT code(s): 80324; HCPCS: G0480).
Confirmation includes the following analytes: Amphetamine, Methamphetamine

Reference Range(s)
Amphetamines    <500 ng/mL
  Amphetamine    <250 ng/mL
  Methamphetamine    <250 ng/mL

Alternative Name(s)
Prescription Drug Monitoring,Pain Management

Drug Monitoring, Amphetamines, with D/L, Quantitative, Urine

Clinical Significance
Drug Monitoring, Amphetamines, with D/L, Quantitative, Urine - Methamphetamine has two isomers, d-methamphetamine (dextromethamphetamine) and l-methamphetamine (levomethamphetamine). d-methamphetamine is most often illicitly manufactured and is considered a drug of abuse (Crystal meth, etc.). It is approved as a treatment for ADHD and obesity, although its use is very limited. l-methamphetamine is used in certain nonprescription inhalers as a decongestant. This test is a definitive assay using a gas chromatography mass spectroscopy (GC-MS) method of analysis. In routine confirmation testing of amphetamines, the specific methamphetamine isomers are not differentiated, and reported as "Methamphetamine". In situations where this is an unexpected result, it may be useful to determine the relative percentages of each isomer present. The presence of the l-isomer at greater than 80% is consistent with the use of non-prescription inhalers. The presence of the d-isomer greater than 20% is consistent with the use of prescribed medication or illegally manufactured methamphetamine. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
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Amphetamine and Methamphetamine
If the Methamphetamine is reported Positive (≥250 ng/mL), Pain Management, Methamphetamine, D/L Isomers, Urine will be performed at an additional charge (CPT code(s): 80374 HCPCS: G0480)

Reference Range(s)
Amphetamine    <250 ng/mL
Methamphetamine    <250 ng/mL

Alternative Name(s)
Prescription Drug Monitoring,Pain Management

Drug Monitoring, Barbiturates, Quantitative, Urine

Clinical Significance
Drug Monitoring, Barbiturates, Quantitative, Urine - The barbiturate class of drugs are substances that are traditionally classified as sedatives. Their principle uses are to calm the patient, produce drowsiness, and/or promote sleep. They are central nervous system (CNS) depressants. The test is a definitive assay using gas chromatography mass spectroscopy (GC/MS) methodology. Therapeutic urine drug monitoring of the barbiturates is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
.
Amobarbital, Butalbital, Pentobarbital, Secobarbital, Phenobarbital

Reference Range(s)
Amobarbital    <100 ng/mL
Butalbital    <100 ng/mL
Pentobarbital    <100 ng/mL
Secobarbital    <100 ng/mL
Phenobarbital    <100 ng/mL

Alternative Name(s)
Prescription Drug Monitoring,Pain Management

Drug Monitoring, Barbiturates, Screen, Urine

Clinical Significance
Drug Monitoring, Barbiturates, Screen, Urine - The barbiturate class of drugs are traditionally classified as sedatives and central nervous system depressants. Their principle uses are to calm the patient, produce drowsiness, and/or promote sleep. The test is a screening assay using a homogeneous enzyme immunoassay method of analysis. Therapeutic urine drug monitoring of the barbiturates is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Urine drug test results equal to or greater than cutoff are reported as positive and results less than cutoff are reported as negative.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.

Reference Range(s)
Barbiturates    <300 ng/mL

Alternative Name(s)
Phenobarbital,Secobarbital,Pain Management,Amobarbital,Prescription Drug Monitoring,Butalbital,Pentobarbital

Drug Monitoring, Barbiturates, with Confirmation, Urine

Clinical Significance
Drug Monitoring, Barbiturates, with Confirmation, Urine - The barbiturate class of drugs are traditionally classified as sedatives and central nervous system depressants. Their principle uses are to calm the patient, produce drowsiness, and/or promote sleep. The test is a screening assay using a homogeneous enzyme immunoassay method of analysis. Presumptive positive screen results are reflexed to a more specific and sensitive liquid chromatography mass spectroscopy (LC/MS/MS) test. Therapeutic urine drug monitoring of the barbiturates is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Urine drug test results equal to or greater than cutoff are reported as positive and results less than cutoff are reported as negative. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
.
Initial screen of the Barbiturates drug class. If screen is positive, a confirmation will be performed at an additional charge (CPT code(s): 80345; HCPCS: G0480).
Confirmation includes the following analytes: Amobarbital, Butalbital, Pentobarbital, Phenobarbital, Secobarbital

Reference Range(s)
Barbiturates    <300 ng/mL
  Amobarbital    <100 ng/mL
  Butalbital    <100 ng/mL
  Pentobarbital    <100 ng/mL
  Phenobarbital    <100 ng/mL
  Secobarbital    <100 ng/mL

Alternative Name(s)
Prescription Drug Monitoring,Pain Management

Drug Monitoring, Base Panel, with Confirmation, Urine

Clinical Significance
Drug Monitoring, Base Panel, with Confirmation, Urine - The test is a screening assay using a homogeneous enzyme immunoassay method of analysis. Presumptive positive screen results are reflexed to a more specific and sensitive liquid chromatography mass spectroscopy (LC/MS/MS) test. Therapeutic urine drug monitoring is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Urine drug test results equal to or greater than cutoff are reported as positive and results less than cutoff are reported as negative. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
.
Initial screen of Benzodiazepines, Cocaine Metabolite, Opiates, and Oxycodone drug classes. Specimen validity consisting of Creatinine, Oxidant, and pH testing.
If screen of drug class is positive, a confirmation of the drug class will be performed at an additional charge (CPT code(s): dependent upon the confirmed drug class).
Confirmation includes the following analytes within their associated drug class:
Benzodiazepines: Alphahydroxyalprazolam, Alphahydroxymidazolam, Alphahydroxytriazolam, Aminoclonazepam, Hydroxyethylflurazepam, Lorazepam, Nordiazepam, Oxazepam, Temazepam
Cocaine Metabolite: Benzoylecgonine
Opiates: Codeine, Hydrocodone, Hydromorphone, Morphine, Norhydrocodone
Oxycodone: Noroxycodone, Oxycodone, Oxymorphone

Alternative Name(s)
Prescription Drug Monitoring,Pain Management

Drug Monitoring, Benzodiazepines, Quantitative, Urine

Clinical Significance
Drug Monitoring, Benzodiazepines, Quantitative, Urine - The benzodiazepine class of drugs are traditionally classified as depressants. They are used therapeutically to produce sedation, induce sleep, relieve anxiety, treat muscle spasms, and to prevent seizures. In general, benzodiazepines act as hypnotics in high doses, anxiolytics in moderate doses, and sedatives in low doses. The test is a definitive assay using liquid chromatography mass spectroscopy (LC/MS/MS) methodology. Therapeutic urine drug monitoring of the benzodiazepines is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
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Alphahydroxyalprazolam, Alphahydroxymidazolam, Alphahydroxytriazolam, Aminoclonazepam, Hydroxyethylflurazepam, Lorazepam, Nordiazepam, Oxazepam, Temazepam

Reference Range(s)
Alphahydroxyalprazolam    <25 ng/mL
Alphahydroxymidazolam    <50 ng/mL
Alphahydroxytriazolam    <50 ng/mL
Aminoclonazepam    <25 ng/mL
Hydroxyethylflurazepam    <50 ng/mL
Lorazepam    <50 ng/mL
Nordiazepam    <50 ng/mL
Oxazepam    <50 ng/mL
Temazepam    <50 ng/mL

Alternative Name(s)
Prescription Drug Monitoring,Pain Management

Drug Monitoring, Benzodiazepines, Screen, Urine

Clinical Significance
Drug Monitoring, Benzodiazepines, Screen, Urine - The benzodiazepine class of drugs are traditionally classified as depressants. They are used therapeutically to produce sedation, induce sleep, relieve anxiety, treat muscle spasms, and to prevent seizures. In general, benzodiazepines act as hypnotics in high doses, anxiolytics in moderate doses, and sedatives in low doses. The test is a screening assay using a homogeneous enzyme immunoassay method of analysis. Therapeutic urine drug monitoring of the benzodiazepines is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Urine drug test results equal to or greater than cutoff are reported as positive and results less than cutoff are reported as negative.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.

Reference Range(s)
Benzodiazepines    <100 ng/mL

Alternative Name(s)
Prescription Drug Monitoring,Pain Management

Drug Monitoring, Benzodiazepines, with Confirmation, Urine

Clinical Significance
Drug Monitoring, Benzodiazepines, with Confirmation, Urine - The benzodiazepine class of drugs are traditionally classified as depressants. They are used therapeutically to produce sedation, induce sleep, relieve anxiety, treat muscle spasms, and to prevent seizures. In general, benzodiazepines act as hypnotics in high doses, anxiolytics in moderate doses, and sedatives in low doses. The test is a screening assay using a homogeneous enzyme immunoassay method of analysis. Presumptive positive screen results are reflexed to a more specific and sensitive liquid chromatography mass spectroscopy (LC/MS/MS) methodology. Therapeutic urine drug monitoring of the benzodiazepines is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Urine drug test results equal to or greater than cutoff are reported as positive and results less than cutoff are reported as negative. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d
.
Initial screen of the Benzodiazepines drug class. If screen is positive, a confirmation will be performed at an additional charge (CPT code(s): 80346; HCPCS: G0480).
Confirmation includes the following analytes: Alphahydroxyalprazolam, Alphahydroxymidazolam, Alphahydroxytriazolam, Aminoclonazepam, Hydroxyethylflurazepam, Lorazepam, Nordiazepam, Oxazepam, Temazepam

Reference Range(s)
Benzodiazepines    <100 ng/mL
  Alphahydroxyalprazolam    <25 ng/mL
  Alphahydroxymidazolam    <50 ng/mL
  Alphahydroxytriazolam    <50 ng/mL
  Aminoclonazepam    <25 ng/mL
  Hydroxyethylflurazepam    <50 ng/mL
  Lorazepam    <50 ng/mL
  Nordiazepam    <50 ng/mL
  Oxazepam    <50 ng/mL
  Temazepam    <50 ng/mL

Alternative Name(s)
Prescription Drug Monitoring,Pain Management

Drug Monitoring, Buprenorphine and Naloxone, Quantitative, Urine

Clinical Significance
Drug Monitoring, Buprenorphine and Naloxone, Quantitative, Urine - This test measures levels of buprenorphine and its metabolite norbuprenorphine in urine. Buprenorphine and norbuprenorphine are biomarkers for monitoring possible use or non-use of buprenorphine. The test is a definitive drug assay using the liquid chromatography/mass spectrometry (LC/MS-MS) method of analysis.

Buprenorphine is an opioid analgesic used for moderate to moderately severe pain. Formulated with naloxone, buprenorphine is used to treat opioid substance use disorders. Less than 11% of the dose is excreted as free and conjugated unchanged drug, while less than 14% is excreted as free and conjugated metabolites.

According to the American Association for Clinical Chemistry (AACC), testing drugs/drug metabolites is recommended and effective for detecting the use of relevant over-the-counter, prescribed, and nonprescribed drugs, as well as illicit substances in pain-management patients. Laboratory testing is more effective than other physician tools for the detection of these substances and is useful for routine monitoring of adherence. Instances where unchanged drug is detected, but metabolite(s) is not, may be indicative of drug added to the specimen after collection (eg, pill shaving, drug spiking).

Note: No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns.

Urine drug test results equal to or greater than cutoff are reported as quantitative values and results less than cutoff are reported as negative. Quantitative values cannot be used to assess the drug dose because the drug is extensively metabolized and excreted in the urine.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
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Buprenorphine, Norbuprenorphine, Naloxone

Reference Range(s)
Buprenorphine    <2 ng/mL
Norbuprenorphine    <2 ng/mL
Naloxone    <2 ng/mL

Alternative Name(s)
Suboxone®,Pain Management,Prescription Drug Monitoring

Drug Monitoring, Buprenorphine, Screen, Urine

Clinical Significance
Drug Monitoring, Buprenorphine, Screen, Urine - Buprenorphine is used for treatment of chronic pain in non-opioid tolerant individuals and has found a significant role in treatment of addiction to other opiates. The test is a screening assay using cloned enzyme donor immunoassay (CEDIA) method of analysis. Therapeutic urine drug monitoring of buprenorphine (and its major metabolite, norbuprenorphine) is important for ensuring compliance to treatment strategies as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking buprenorphine. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Urine drug test results equal to or greater than cutoff are reported as positive and results less than cutoff are reported as negative.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.

Reference Range(s)
Buprenorphine    <5 ng/mL

Alternative Name(s)
Naloxone,Pain Management,Prescription Drug Monitoring

Drug Monitoring, Buprenorphine, with Confirmation, includes Naloxone, Urine

Clinical Significance
Drug Monitoring, Buprenorphine, with Confirmation, includes Naloxone, Urine - Patients treated with buprenorphine-naloxone co-formulation will demonstrate both naloxone and buprenorphine/norbuprenorphine drug analysis. Naloxone is not detected with buprenorphine-only use.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
.
Initial screen of the Buprenorphine drug class. If screen is positive, a confirmation will be performed at an additional charge (CPT code(s): 80348, 80362; HCPCS: G0480).
Confirmation includes the following analytes: Buprenorphine, Norbuprenorphine, Naloxone

Reference Range(s)
Buprenorphine    <5 ng/mL
  Buprenorphine    <2 ng/mL
  Norbuprenorphine    <2 ng/mL
  Naloxone    <2 ng/mL

Alternative Name(s)
Naloxone,Suboxone®,Pain Management,Prescription Drug Monitoring

Drug Monitoring, Carisoprodol Metabolite, Quantitative, Urine

Clinical Significance
Drug Monitoring, Carisoprodol Metabolite, Quantitative, Urine - Carisoprodol is used clinically as a muscle relaxant and sedative. Carisoprodol's metabolite, Meprobamate, is commonly accepted as the primary urinary metabolite in man. Detection of this metabolite is indicative of ingestion of carisoprodol. The test is a definitive assay using liquid chromatography mass spectroscopy (LC/MS/MS) methodology. Therapeutic urine drug monitoring of propoxyphene is important for ensuring compliance to treatment strategies. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
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Meprobamate

Reference Range(s)
Meprobamate    <1000 ng/mL

Alternative Name(s)
Prescription Drug Monitoring,Pain Management