Drug Monitoring, Benzodiazepines, Quantitative, Urine

The Drug Monitoring, Benzodiazepines, Quantitative, Urine test contains 1 test with 10 biomarkers.

Drug Monitoring, Benzodiazepines, Quantitative, Urine

Alternative Name(s)
Prescription Drug Monitoring, Pain Management

Clinical Significance
Drug Monitoring, Benzodiazepines, Quantitative, Urine - The benzodiazepine class of drugs are traditionally classified as depressants. They are used therapeutically to produce sedation, induce sleep, relieve anxiety, treat muscle spasms, and to prevent seizures. In general, benzodiazepines act as hypnotics in high doses, anxiolytics in moderate doses, and sedatives in low doses. The test is a definitive assay using liquid chromatography mass spectroscopy (LC/MS/MS) methodology. Therapeutic urine drug monitoring of the benzodiazepines is important for ensuring compliance to treatment strategies, as well as ensuring non-diversion for illicit purposes. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. The safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Quantitative values cannot be used to assess the drug dose because the drug is extensively metabolized and excreted in the urine.

Reference Range(s)

  • Alphahydroxyalprazolam    <25 ng/mL
  • Alphahydroxymidazolam    <50 ng/mL
  • Alphahydroxytriazolam    <50 ng/mL
  • Aminoclonazepam    <25 ng/mL
  • Hydroxyethylflurazepam    <50 ng/mL
  • Lorazepam    <50 ng/mL
  • Nordiazepam    <50 ng/mL
  • Oxazepam    <50 ng/mL
  • Temazepam    <50 ng/mL
     

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Alphahydroxyalprazolam

Alphahydroxymidazolam

Alphahydroxytriazolam

Aminoclonazepam

Hydroxyethylflurazepam

Lorazepam

Medmatch Nordiazepam

Nordiazepam

Oxazepam

Temazepam

*Process times are an estimate and are not guaranteed. The lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

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