Metabolic Syndrome

The metabolic syndrome tests measure the metabolic changes associated with an increased risk for developing cardiovascular disease (CVD) and type 2 diabetes mellitus. Our tests include HDL cholesterol level, triglyceride level, and fasting blood sugar. Order from Ulta Lab Tests today with results sent confidentially online. 


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The adiponectin ELISA assay quantitatively measures human adiponectin in serum. It has been shown that decreased expression of adiponectin correlates with insulin resistance. Adiponectin appears to be a potent insulin enhancer linking adipose tissue and whole body glucose metabolism.

Apolipoprotein A1 (APO A1) has been reported to be a better predictor than HDL cholesterol and triglycerides for Coronary Artery Disease (CAD). Low levels of APO A1 in serum are associated with increased risk of CAD. The measurement of APO A1 may be of value in identifying patients with atherosclerosis. Apolipoprotein B (APO B) has been reported to be a more powerful indicator of CAD than total cholesterol or LDL cholesterol in angiographic CAD and in survivors of myocardial infarction. In some patients with CAD, APO B is elevated even in the presence of normal LDL cholesterol.

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C-Peptide is useful in the evaluation of pancreatic beta cell function and for determining the source of insulin in patients with hyperinsulinemic hypoglycemia.

Increased CRP levels are found in inflammatory conditions including: bacterial infection, rheumatic fever, active arthritis, myocardial infarction, malignancies and in the post-operative state. This test cannot detect the relatively small elevations of CRP that are associated with increased cardiovascular risk.

C-Reactive Protein Cardiac (hs CRP) Useful in predicting risk for cardiovascular disease.


There is a correlation between increased risk of premature heart disease with decreasing size of LDL particles. Ion mobility offers the only direct measurement of lipoprotein particle size and concentration for each lipoprotein from HDL3 to large VLDL.

Catecholamines, Fractionated and VMA, 24-Hour Urine without Creatinine

Catecholamines are a group of similar substances released into the blood in response to physical or emotional stress. The primary catecholamines are dopamine, epinephrine (adrenaline), and norepinephrine. Catecholamine testing measures the amounts of these hormones in the urine and/or blood. Urine testing is recommended over blood testing.

Patient Preparation

It is preferable for the patient to be off medications for three days prior to collection. However, common antihypertensives (diuretics, ACE inhibitors, calcium channel blockers, alpha and beta blockers) may cause minimal or no interference.
Patient should avoid tobacco, tea, coffee, and strenuous exercise for 8-12 hours prior to collection.



Clinical Significance

Urine chloride excretion approximates the dietary intake. The chloride content of most foods parallel that of sodium. An increase in urine chloride may result from water deficient dehydration, diabetic acidosis, Addison's disease, and salt-losing renal disease. Decreased urine levels are seen in congestive heart failure, severe diaphoresis and in hypochloremic metabolic alkalosis due to prolonged vomiting.


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To screen for and monitor kidney dysfunction in those with known or suspected kidney disease. Cystatin C is a relatively small protein that is produced throughout the body by all cells that contain a nucleus and is found in a variety of body fluids, including the blood. It is produced, filtered from the blood by the kidneys, and broken down at a constant rate. This test measures the amount of cystatin C in blood to help evaluate kidney function.Cystatin C is filtered out of the blood by the glomeruli, clusters of tiny blood vessels in the kidneys that allow water, dissolved substances, and wastes to pass through their walls while retaining blood cells and larger proteins. What passes through the walls of the glomeruli forms a filtrate fluid. From this fluid, the kidneys reabsorb cystatin C, glucose, and other substances. The remaining fluid and wastes are carried to the bladder and excreted as urine. The reabsorbed cystatin C is then broken down and is not returned to the blood.


Elevated GGT is found in all forms of liver disease. Measurement of GGT is used in the diagnosis and treatment of alcoholic cirrhosis, as well as primary and secondary liver tumors. It is more sensitive than alkaline phosphatase, the transaminases, and leucine aminopeptidase in detecting obstructive jaundice, cholangitis, and cholecystitis. Normal levels of GGT are seen in skeletal diseases; thus, GGT in serum can be used to ascertain whether a disease, suggested by elevated alkaline phosphatase, is skeletal or hepatobiliary.

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Serum glucose levels may be abnormally high (hyperglycemia) or abnormally low (hypoglycemia). Glucose measurements are used in the diagnosis and treatment of carbohydrate metabolic disorders including diabetes mellitus, idiopathic hypoglycemia, and pancreatic islet cell neoplasm.

A Hemoglobin (Hb) A1c Blood Test evaluates the average amount of glucose in the blood. The A1c test will help determine whether you are at a higher risk of developing diabetes; to help diagnose diabetes and prediabetes; to monitor diabetes and to aid in treatment decisions.

To assist with control of blood glucose levels, the American Diabetes Association (ADA) has recommended glycated hemoglobin testing (HbA1c) twice a year for patients with stable glycemia, and quarterly for patients with poor glucose control. Interpretative ranges are based on ADA guidelines.


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For diagnosis and monitoring of diabetes and insulin-secreting tumors.

Serum iron quantification is useful in confirming the diagnosis of iron-deficiency anemia or hemochromatosis. The measurement of total iron binding in the same specimen may facilitate the clinician''s ability to distinguish between low serum iron levels caused by iron deficiency from those related to inflammatory neoplastic disorders. The assay for iron measures the amount of iron which is bound to transferrin. The total iron binding capacity (TIBC) measures the amount of iron that would appear in blood if all the transferrin were saturated with iron. It is an indirect measurement of transferri

Lipid Panel includes: Total Cholesterol, HDL Cholesterol, Triglycerides, LDL-Cholesterol (calculated), Cholesterol/HDL Ratio (calculated), Non-HDL Cholesterol (calculated)Total cholesterol —this test measures all of the cholesterol in all the lipoprotein particles.High-density lipoprotein cholesterol (HDL-C) — measures the cholesterol in HDL particles; often called "good cholesterol" because it removes excess cholesterol and carries it to the liver for removal.Direct LDL - Low-density lipoprotein cholesterol (LDL-C) — calculates the cholesterol in LDL particles; often called "bad cholesterol" because it deposits excess cholesterol in walls of blood vessels, which can contribute to atherosclerosis. Usually, the amount of LDL cholesterol (LDL-C) is calculated using the results of total cholesterol, HDL-C, and triglycerides.Triglycerides — measures all the triglycerides in all the lipoprotein particles; most is in the very low-density lipoproteins (VLDL).


A lipid panel includes:Total cholesterol —this test measures all of the cholesterol in all the lipoprotein particles.High-density lipoprotein cholesterol (HDL-C) — measures the cholesterol in HDL particles; often called "good cholesterol" because it removes excess cholesterol and carries it to the liver for removal.Low-density lipoprotein cholesterol (LDL-C) — calculates the cholesterol in LDL particles; often called "bad cholesterol" because it deposits excess cholesterol in walls of blood vessels, which can contribute to atherosclerosis. Usually, the amount of LDL cholesterol (LDL-C) is calculated using the results of total cholesterol, HDL-C, and triglycerides.Triglycerides — measures all the triglycerides in all the lipoprotein particles; most is in the very low-density lipoproteins (VLDL).Very low-density lipoprotein cholesterol (VLDL-C) — calculated from triglycerides/5; this formula is based on the typical composition of VLDL particles.Non-HDL-C — calculated from total cholesterol minus HDL-C.Cholesterol/HDL ratio — calculated ratio of total cholesterol to HDL-C.


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Elevated concentrations of Lp(a) are associated with increased risk of coronary artery disease

Metabolic Discovery Comprehensive Panel

This thorough set of tests helps assess your metabolism. Are you storing too much fat and sugar or perhaps too little? Are you insulin resistant with subsequent inflammation? You can run this panel to discover whether your diet, fitness and nutritional habits are providing you the metabolic health and longevity you deserve. Don’t settle for one-size-fits-all health advice.

Preparation: Fast for 10-16 hours, overnight. Drink enough water and take your prescribed medications. No coffee or vigorous exercise on the morning of the blood draw.

CONTAINS ALL OF THE TESTS IN THE Metabolic Discovery Panel

  • CBC (includes Differential and Platelets)
  • Comprehensive Metabolic Panel (CMP)
  • Ferritin
  • Hemoglobin A1c with eAG
  • Insulin
  • Lipid Panel with Ratios
  • Vitamin B12 (Cobalamin)
  • Vitamin D, 25-Hydroxy, Total, Immunoassay

PLUS

  • Adiponectin 
  • Iron and Total Iron Binding Capacity (TIBC)
  • Leptin
  • T3, Free
  • T4, Free
  • TSH

Identifying patients who have metabolic syndrome and who are thus at higher risk of diabetes, coronary heart disease or stroke. Identifying patients who are insulin resistant (fasting insulin at or above the 75th percentile) and who are thus at higher risk of diabetes, coronary heart disease, stroke, or liver disease. Monitoring of risk factors and insulin levels after life style change, medication use, or both.



Diabetic nephropathy is a complication of diabetes and is characterized by proteinuria. Before overt proteinuria develops, albumin excretion increases in those diabetic patients who are destined to develop diabetic nephropathy. There is a need to identify small, but abnormal, increases in the excretion of urinary albumin (in the range of 30-300 mg/day, ie, microalbuminuria). The National Kidney Foundation guidelines for the management of patients with diabetes and microalbuminuria recommend that all type 1 diabetic patients older than 12 years and all type 2 diabetic patients younger than 70 years have their urine tested for microalbuminuria yearly when they are under stable glucose control.

Clinical Significance

The OxLDL test may be ordered for individuals at low or intermediate risk of metabolic syndrome or cardiovascular disease. In addition, this test is useful in individuals who have cardiovascular disease and are at risk for an adverse cardiac event.

Alternative Name(s) 

Oxidized low-density lipoprotein

 



5 Benefits of Metabolic Syndrome Tests

One-third of adults in the United States suffer from metabolic syndrome. A sedentary lifestyle and poor diet both contribute to this health condition.

metabolic syndrome test is a simple way to check your health. Blood pressure, blood glucose levels, and other body systems need to stay on track to ensure the body is functioning properly.

What is Metabolic Syndrome?

Metabolic Syndrome is not a disease; it is the combination of multiple health issues. High blood sugar, high cholesterol, high triglyceride levels, fatty midsection, and high blood pressure all contribute to this medical condition.

A metabolic syndrome diagnosis comes when a patient suffers from at least three of these issues. These issues can lead to larger, more serious health issues.

Causes of Metabolic Syndrome

Although a combination of factors cause Metabolic Syndrome, according to the Mayo Clinic, the biggest contributors are obesity, inactivity, and insulin resistance.

Age, being of Hispanic origin, and diabetes will increase the chances of developing metabolic syndrome.

Signs and Symptoms of Metabolic Syndrome

Because there are so many factors that play into the diagnosis of Metabolic Syndrome, it is important to pay attention to small symptoms.

Blood Sugar

High blood sugar, also known as hyperglycemia, can cause Type 2 Diabetes. A healthy blood sugar level for adults who do not suffer from Type 1 or Type 2 diabetes is 90 - 110 mg/dL.

High blood sugar can come from illness and stress, but most often, it is the result of over-eating. A person with high blood sugar levels can experience exhaustion, extreme thirst, poor eyesight, and frequent urination.

Continual high blood sugar levels can lead to heart disease and damage to the nerves, kidneys, blood vessels, eyes, feet, and mouth.

Managing high blood sugar can be easy with a healthy diet, portion control, and daily exercise.

Cholesterol

There are both good and bad types of Cholesterol. While good cholesterol helps the body's cell system, bad cholesterol will override any work done.

Bad cholesterol causes arteries to clog and increases the chance of blood clots. This can lead to heart attacks, stroke, and heart disease.

While high cholesterol can sometimes be genetic, oftentimes, it is the result of an unhealthy lifestyle. There are no symptoms of high cholesterol, so blood tests must be taken to detect it.

Triglyceride Levels

Triglycerides are fatty deposits in the blood used for energy. Sometimes referred to as "lipids," triglycerides are derived from foods like carbohydrates.

The target level for triglycerides is less than 150 mg per deciliter. Higher levels increase the risk of heart disease. 

Like cholesterol, there are no symptoms for high triglycerides. Levels can be checked with a blood test after a fast.

Healthy eating and daily movement are both important steps to take to maintain healthy triglyceride levels.

Blood Pressure

Blood pressure is the rate at which blood flows through the blood vessels. If the pressure is too high, this can cause high blood pressure or hypertension.

Blood pressure is measured by looking at the systolic number, on the top, compared to the diastolic number, on the bottom. Healthy blood pressure is 120/80 or slightly below.

The higher the numbers, the greater the risk for stroke, vision loss, heart attack, or heart failure.

High blood pressure is caused by a family history of hypertension, low or no exercise, and an unhealthy diet. Conditions like diabetes or life stages like pregnancy can also affect blood pressure levels.

The best way to know if you have high blood pressure is to check it regularly.

Obesity

Unlike the conditions listed above, obesity is different for every person. Body Mass Index (BMI) determines if a person is overweight.

The World Health Organization (WHO) classifies adults with a BMI of 25 or greater to be overweight and adults with a BMI of 30 or greater to be obese.

Those with excess weight around the midsection are at a higher risk for heart disease and diabetes. This is because most of the organs are in the middle section of the body. The fat in that area releases fatty acids, which are well absorbed by the organs.

Daily exercise and a healthy diet of whole foods can reduce weight and create a healthier lifestyle.

Lab Tests for Metabolic Syndrome

Because several factors that determine a metabolic syndrome diagnosis cannot be physically seen, lab tests can be very helpful in providing insight.

Tests will review several factors, including blood pressure, triglyceride levels, and cholesterol levels.

Benefits of Metabolic Syndrome Test

Metabolic Syndrome can be tracked and even prevented with regular blood work. Ulta Lab Tests provides these important lab tests to screen for, monitor, and manage the metabolic syndrome.

1. In-Depth and Convenient Testing to Help You Learn More About Your Health

Ulta Lab Tests provides several in-depth options for Metabolic Syndrome blood tests. These include glucose control testing, lipoprotein screening, and an advanced Metabolic Syndrome test.

There are 2,100 approved patient service centers across the United States to conduct screenings. A prescription is not needed, and you can arrange your test at any time.

2. Prevention of Metabolic Syndrome

The earlier you learn about your health, the sooner you can take steps to improve it. If test results show you are on the fast path to metabolic syndrome, there are steps to remedy this.

3. Early Metabolic Syndrome Treatment

Early detection of a medical illness can help heal the body. When diseases are not caught soon enough, it can be impossible to reverse the harmful damages.

4. Help Your Family Members

Many diseases are genetic, so it is important to inform any family members that may be susceptible to it. Early diagnosis can help others make lifestyle changes to help them end up in the same situation.

5. Change Your Life For the Better

Once you receive your lab results, you can make the necessary changes to improve your health and your life. Don't delay in taking the next step to bettering yourself.

How to Arrange Lab Testing

Ulta Labs Tests makes it easy to track your health. Visit Ulta Lab Tests and search our database for your desired test. Buy your test online, and after checkout, you will receive a lab requisition.

Take your lab requisition to the nearest Patient Service Center, and they will collect your specimen. Some tests may require that you fast, temporarily stop supplements, or skip brushing your teeth. This information is all clearly stated to make the process very clear and easy to understand.

Results will be ready within a few days and posted to your online patient dashboard.

Taking Control of Your Health

Metabolic Syndrome is on the rise in the United States. Being proactive with your health can not only prevent you from a diagnosis, but it can also help you learn more about your body along the way.

Ulta Lab Tests Metabolic Syndrome Test is very accurate and reliable and can help you make informed decisions about your health. Confidential results will equip you with the knowledge to take the next step in improving your health.

Order your metabolic syndrome lab test today. Take charge of your health and track your progress with Ulta Lab Tests.

Order your metabolic syndrome lab test today, and your results will be provided to you securely and confidentially online in 24 to 48 hours for most tests. Take charge of your health and track your progress with Ulta Lab Tests.