Calcium Most Popular

The Calcium test contains 1 test with 1 biomarker.

Brief Description: A Calcium test measures the level of calcium in the blood. Calcium is a crucial mineral that plays a vital role in various bodily functions, including bone health, muscle contractions, nerve transmission, and blood clotting. This test helps assess the amount of calcium present in the blood, which can be useful in diagnosing certain medical conditions and monitoring the effectiveness of treatments.

Also Known As: Ca Test, Serum Calcium Test, Calcium Blood Test

Collection Method: Blood Draw

Specimen Type: Serum

Test Preparation: No preparation required

When is a Calcium test ordered?

A blood calcium test is frequently requested during a general medical evaluation. It's usually part of the comprehensive metabolic panel or the basic metabolic panel, two sets of tests that can be done during an initial evaluation or as part of a routine medical checks.

Many people do not experience symptoms of high or low calcium until their levels are dangerously high or low.

When a person has certain types of cancer, kidney illness, or has had a kidney transplant, calcium monitoring may be required. When someone is being treated for abnormal calcium levels, monitoring may be required to determine the effectiveness of medications such as calcium or vitamin D supplements.

What does a Calcium blood test check for?

Calcium is one of the most plentiful and vital minerals in the human body. It is required for cell signaling as well as the proper operation of muscles, nerves, and the heart. Calcium is essential for blood clotting as well as bone growth, density, and maintenance. This test determines how much calcium is present in the blood.

Calcium is found complexed in the bones for 99 percent of the time, while the remaining 1% circulates in the blood. Calcium levels are closely monitored; if too little is absorbed or consumed, or if too much is lost through the kidney or stomach, calcium is removed from bone to keep blood concentrations stable. Approximately half of the calcium in the blood is metabolically active and "free." The other half is "bound" to albumin, with a minor proportion complexed to anions like phosphate, and both of these forms are metabolically inactive.

Blood calcium can be measured using two different tests. The free and bound forms of calcium are measured in the total calcium test. Only the free, physiologically active form of calcium is measured in the ionized calcium test.

Lab tests often ordered with a Calcium test:

When a Calcium test is ordered, it's often part of a broader evaluation of bone metabolism, parathyroid function, and other related health issues. Here are some tests commonly ordered alongside it:

  1. Phosphorus:

    • Purpose: To measure the level of phosphorus in the blood.
    • Why Is It Ordered: Calcium and phosphorus levels are closely linked in bone metabolism and kidney function. Abnormal levels can indicate various metabolic bone diseases.
  2. Magnesium:

    • Purpose: To measure the level of magnesium in the blood.
    • Why Is It Ordered: Magnesium plays a role in regulating calcium balance and is important for proper muscle and nerve function.
  3. Vitamin D Tests 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D:

    • Purpose: To assess vitamin D status, which is crucial for calcium absorption and bone health.
    • Why Is It Ordered: Vitamin D deficiency can lead to disturbances in calcium metabolism and bone diseases.
  4. Parathyroid Hormone (PTH):

    • Purpose: To measure the level of PTH, which regulates calcium and phosphorus levels.
    • Why Is It Ordered: To assess parathyroid gland function, as PTH is a key regulator of calcium levels.
  5. Kidney Function Test:

    • Purpose: To evaluate kidney function.
    • Why Is It Ordered: The kidneys play a crucial role in regulating calcium levels, and kidney disease can affect calcium metabolism.
  6. Alkaline Phosphatase (ALP):

    • Purpose: To measure ALP, an enzyme related to bone activity.
    • Why Is It Ordered: Elevated ALP can indicate increased bone turnover, which can be associated with certain bone diseases.
  7. Complete Blood Count (CBC):

    • Purpose: Provides a broad picture of overall blood health.
    • Why Is It Ordered: To assess general health and detect any conditions that might be related to or affect calcium levels, such as cancers or chronic diseases.
  8. Electrolyte Panel:

    • Purpose: To measure key electrolytes in the blood.
    • Why Is It Ordered: To assess overall electrolyte balance, which can be influenced by and impact calcium levels.

These tests, when ordered alongside a Calcium test, provide a comprehensive view of an individual’s bone metabolism, parathyroid function, and overall metabolic status. They are crucial for diagnosing and managing conditions affecting calcium balance, such as hypercalcemia, hypocalcemia, parathyroid disorders, and bone diseases. The specific combination of tests will depend on the individual’s symptoms, medical history, and initial test results.

Conditions where a Calcium test is recommended:

The Calcium test may be necessary for the following conditions or diseases:

  1. Osteoporosis and Bone Health Concerns: To evaluate bone health and monitor the effectiveness of osteoporosis treatments.

  2. Hyperparathyroidism: To diagnose and monitor overactive parathyroid glands.

  3. Kidney Disorders: To assess kidney function and its impact on calcium regulation.

  4. Vitamin D Deficiency: To check for possible causes of low calcium levels due to inadequate vitamin D absorption.

How does my health care provider use a Calcium test?

A blood calcium test is used to screen for, diagnose, and monitor a variety of bone, heart, nerve, kidney, and tooth disorders. If a person has signs of a parathyroid disease, malabsorption, or an overactive thyroid, the test may be ordered.

A total calcium level is frequently checked as part of a standard health check. It's part of the comprehensive metabolic panel and the basic metabolic panel, which are both collections of tests used to diagnose or monitor a range of ailments.

When a total calcium result is abnormal, it is interpreted as a sign of an underlying disease. Additional tests to assess ionized calcium, urine calcium, phosphorus, magnesium, vitamin D, parathyroid hormone, and PTH-related peptide are frequently performed to assist determine the underlying problem. PTH and vitamin D are in charge of keeping calcium levels in the blood within a narrow range of values.

Measuring calcium and PTH combined can assist identify whether the parathyroid glands are functioning normally if the calcium is abnormal. Testing for vitamin D, phosphorus, and/or magnesium can assist evaluate whether the kidneys are excreting the right amount of calcium, and measuring urine calcium can help detect whether additional deficits or excesses exist. The balance of these many compounds is frequently just as critical as their concentrations.

The total calcium test is the most common test used to determine calcium status. Because the balance between free and bound calcium is usually constant and predictable, it is a reliable reflection of the quantity of free calcium present in the blood in most cases. However, the balance between bound and free calcium is altered in some persons, and total calcium is not a good indicator of calcium status. Ionized calcium measurement may be required in certain cases. Critically sick patients, those receiving blood transfusions or intravenous fluids, patients undergoing major surgery, and persons with blood protein disorders such low albumin are all candidates for ionized calcium testing.

What do my Calcium test results mean?

The amount of calcium circulating in the blood is not the same as the amount of calcium in the bones.

A feedback loop including PTH and vitamin D regulates and stabilizes calcium uptake, utilization, and excretion. Conditions and disorders that disturb calcium control can induce abnormal acute or chronic calcium elevations or declines, resulting in hypercalcemia or hypocalcemia symptoms.

Total calcium is usually tested instead of ionized calcium since it is easier to do and requires no additional treatment of the blood sample. Because the free and bound forms of calcium make up about half of the total, total calcium is usually a decent depiction of free calcium. Because nearly half of the calcium in blood is bonded to protein, high or low protein levels might alter total calcium test findings. In these circumstances, an ionized calcium test is more appropriate for measuring free calcium.

A normal total or ionized calcium test, when combined with other normal laboratory findings, indicates that a person's calcium metabolism is normal and blood levels are properly managed.

Most Common Questions About the Calcium test:

Understanding the Calcium Test

What is the calcium test?

The calcium test is a blood test that measures the amount of calcium in your blood. Calcium is a vital mineral that is essential for many body functions, including bone health, nerve function, muscle contraction, and blood clotting.

Why would a doctor recommend a calcium test?

A doctor might recommend a calcium test if they suspect a calcium imbalance, which could be due to conditions such as kidney disease, parathyroid disorders, or bone disease.

Can the calcium test differentiate between the types of calcium in the body?

The total calcium test measures both free and bound calcium. However, for a more specific measure, an ionized calcium test can measure the amount of calcium that is free or unbound and bioactive.

Interpreting Calcium Test Results

What do high levels of calcium in the test results indicate?

High calcium levels, or hypercalcemia, can indicate several conditions including overactive parathyroid glands (hyperparathyroidism), certain types of cancer, excessive vitamin D intake, or certain types of medications.

What do low levels of calcium in the test results indicate?

Low calcium levels, or hypocalcemia, can suggest conditions like underactive parathyroid glands (hypoparathyroidism), vitamin D deficiency, kidney disease, pancreatitis, or low protein levels in the blood.

How does age affect normal ranges for the calcium test?

Normal calcium levels can vary slightly depending on a person's age. For example, infants and children have higher normal calcium levels than adults due to the demands of growth.

How does the body maintain calcium levels and how can this affect the test?

The body maintains calcium levels through hormones like parathyroid hormone and calcitonin. Disorders affecting these hormones can lead to imbalances in calcium levels, affecting test results.

The Calcium Test and Specific Health Conditions

How is the calcium test used in diagnosing parathyroid disorders?

Parathyroid disorders often cause imbalances in blood calcium levels. High calcium levels may suggest hyperparathyroidism, while low levels may suggest hypoparathyroidism.

How can a calcium test help in the diagnosis and management of kidney disease?

In kidney disease, the kidneys' ability to manage calcium and other minerals can be impaired, leading to abnormal calcium levels. This test can aid in diagnosis and monitoring of kidney disease.

Can a calcium test help diagnose bone diseases?

Yes, bone diseases like osteoporosis and Paget's disease can cause changes in blood calcium levels, although this test alone is not sufficient for diagnosis.

How is a calcium test used in diagnosing cancer?

Some cancers can cause elevated calcium levels, particularly if they have spread to the bones or are producing parathyroid hormone-related protein (PTHrP). The test can help in diagnosing and monitoring these cancers.

Can a calcium test be used to evaluate vitamin D deficiency?

Yes, as vitamin D is necessary for the body to absorb and utilize calcium effectively, a calcium test can indirectly suggest vitamin D deficiency if levels are found to be low.

The Calcium Test and Diet

How can diet affect calcium test results?

Diet can affect calcium levels. Consuming too much or too little calcium can cause hypercalcemia or hypocalcemia, respectively.

Can calcium supplements affect the calcium test results?

Yes, taking calcium supplements can raise blood calcium levels and may cause hypercalcemia if taken in excess.

Can the calcium test be used to monitor the effectiveness of dietary changes or supplements?

Yes, if dietary changes or supplements have been recommended to address calcium imbalance, this test can monitor their effectiveness.

The Calcium Test and Medications

Can certain medications affect the calcium test results?

Yes, certain medications, such as diuretics, lithium, and some types of antacids, can affect calcium levels.

Can the calcium test help guide dosing for certain medications?

Yes, in some cases. For instance, patients on calcium channel blockers might require monitoring of their calcium levels.

Can a calcium test be used to monitor patients on medications that may affect bone health?

Yes, medications like corticosteroids can affect bone health and calcium levels. Monitoring calcium can be part of managing these medication effects.

The Calcium Test and Other Diagnostic Tools

How is the calcium test used in conjunction with other tests?

The calcium test is often used with tests for phosphorus, magnesium, vitamin D, and parathyroid hormone to provide a comprehensive view of bone metabolism and parathyroid function.

How does the calcium test relate to a bone density scan?

While the calcium test can provide information about potential bone health, a bone density scan provides more direct information about the density and strength of the bones.

Can a calcium test be used along with tests for kidney function?

Yes, calcium levels can be affected by kidney function, and this test is often used along with tests like the creatinine clearance test or estimated glomerular filtration rate (eGFR).

How is the calcium test used in conjunction with a urine calcium test? 

A urine calcium test measures how much calcium is excreted in the urine. The two tests together can help diagnose certain conditions that lead to abnormal calcium levels.

Can a calcium test be used alongside other tests for electrolyte imbalances?

Yes, calcium is one of the body's electrolytes, and this test may be performed along with tests for other electrolytes like potassium and sodium.

Is the calcium test a part of general blood testing panels?

Yes, the calcium test is often included in comprehensive metabolic panels, which are common blood tests ordered as part of a general health examination.

How often should a calcium test be repeated for monitoring chronic conditions?

The frequency of testing depends on the specific condition and the doctor's assessment. In some cases, it may be recommended every few months or yearly.

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Calcium

You have more calcium in your body than any other mineral. Calcium has many important jobs. The body stores more than 99 percent of its calcium in the bones and teeth to help make and keep them strong. The rest is throughout the body in blood, muscle and the fluid between cells. Your body needs calcium to help muscles and blood vessels contract and expand, to secrete hormones and enzymes and to send messages through the nervous system.
*Process times are an estimate and are not guaranteed. The lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

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