The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.


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The Adiponectin test contains 1 test with 1 biomarker.

Brief Description: The Adiponectin test measures the concentration of adiponectin—a hormone secreted by adipose tissue—in the blood. Adiponectin plays a significant role in regulating insulin sensitivity, glucose metabolism, inflammation, and lipid metabolism. This test provides insights into the individual's metabolic health and risk of various metabolic disorders.

Collection Method: Blood Draw

Specimen Type: Serum

Test Preparation: Overnight fasting is required

When and Why an Adiponectin Test May Be Ordered:

Healthcare providers may recommend the Adiponectin test to evaluate an individual's metabolic health, especially in cases involving insulin resistance, obesity, type 2 diabetes, or cardiovascular risk assessment. It's often ordered in combination with other tests to assess overall metabolic and cardiovascular risk profiles.

What the Adiponectin Test Checks For:

The Adiponectin test checks for the level of adiponectin in the blood. This hormone is known to have anti-inflammatory and insulin-sensitizing effects. Lower levels of adiponectin are associated with increased insulin resistance, higher risk of type 2 diabetes, and cardiovascular diseases. The test helps assess the individual's metabolic state and their susceptibility to metabolic disorders.

Other Lab Tests That May Accompany an Adiponectin Test:

When an Adiponectin test is ordered, it's usually part of a broader evaluation of metabolic health and cardiovascular risk. Here are some tests commonly ordered alongside it:

  1. Fasting Blood Glucose and Hemoglobin A1c (HbA1c):

    • Purpose: To measure blood sugar levels and long-term glucose control.
    • Why Is It Ordered: To assess for diabetes or prediabetes, as adiponectin levels can be inversely related to insulin sensitivity and glucose metabolism.
  2. Lipid Profile:

    • Purpose: To measure levels of cholesterol and triglycerides.
    • Why Is It Ordered: To evaluate cardiovascular risk, as adiponectin is linked to lipid metabolism and atherosclerosis.
  3. Insulin and C-Peptide Tests:

    • Purpose: To measure insulin production and secretion.
    • Why Is It Ordered: To assess insulin resistance and beta-cell function, particularly in the context of type 2 diabetes or metabolic syndrome.
  4. Leptin Test:

    • Purpose: To measure leptin, another hormone produced by fat cells.
    • Why Is It Ordered: To evaluate leptin resistance and its relationship with obesity and metabolic disorders, as leptin and adiponectin can have reciprocal effects.
  5. High-Sensitivity C-Reactive Protein (hs-CRP):

    • Purpose: To detect low levels of inflammation in the body.
    • Why Is It Ordered: To assess systemic inflammation, which is a risk factor for cardiovascular disease and is often elevated in metabolic syndrome.
  6. Liver Function Test:

    • Purpose: To assess liver health.
    • Why Is It Ordered: To evaluate liver function, as non-alcoholic fatty liver disease (NAFLD) is often associated with metabolic syndrome and altered adiponectin levels.

These tests, when ordered alongside an Adiponectin test, provide a comprehensive evaluation of metabolic health and cardiovascular risk. They are crucial for assessing the risk of diabetes, cardiovascular disease, and other metabolic disorders. The specific combination of tests will depend on the individual’s risk factors, symptoms, and medical history.

Conditions or Diseases Requiring an Adiponectin Test:

The Adiponectin test is essential for diagnosing and monitoring various conditions, including:

  1. Insulin Resistance and Type 2 Diabetes: Low adiponectin levels are associated with insulin resistance and an increased risk of developing type 2 diabetes.

  2. Obesity: Individuals with obesity often have lower adiponectin levels, contributing to metabolic disturbances and increased cardiovascular risk.

  3. Cardiovascular Diseases: Low adiponectin levels are linked to a higher risk of cardiovascular diseases due to their impact on inflammation and lipid metabolism.

Utilization of Adiponectin Test Results by Health Care Providers:

Healthcare providers use the results of the Adiponectin test to assess an individual's metabolic health, insulin sensitivity, and cardiovascular risk. Low adiponectin levels can prompt discussions about lifestyle modifications, such as diet and exercise, to improve metabolic markers. The results guide treatment decisions, risk assessment, and preventive strategies against metabolic and cardiovascular diseases.

Most Common Questions About the Adiponectin test:

Purpose and Indications for the Adiponectin Test

Why is the Adiponectin test ordered?

The Adiponectin test is primarily ordered to gauge the risk of developing type 2 diabetes and cardiovascular disease. Adiponectin is a protein hormone produced by adipose tissue that plays a role in regulating glucose and fat metabolism. Abnormally low levels are often associated with obesity and may indicate an increased risk of these conditions.

How does the Adiponectin test contribute to understanding metabolic syndrome?

The Adiponectin test, by assessing the levels of the adiponectin hormone, provides insights into an individual's metabolic health. Reduced adiponectin levels can indicate insulin resistance, a hallmark of metabolic syndrome, and offer a clearer understanding of a patient's risk profile for associated complications.

Clinical Significance of Test Results

What does a low Adiponectin test result indicate?

Low levels of adiponectin are commonly linked with increased body weight, especially visceral fat. Such levels can also correlate with a higher risk of type 2 diabetes, heart disease, and some inflammatory conditions. Conversely, higher adiponectin levels have been associated with a reduced risk for these conditions.

How is the Adiponectin test used in the context of other metabolic tests?

In clinical settings, the Adiponectin test might not be used in isolation but combined with other metabolic tests like insulin resistance tests, lipid profiles, and inflammatory markers. Together, these tests provide a comprehensive picture of metabolic health and cardiovascular risk.

Interpretation and Follow-up

If my Adiponectin test result is abnormal, what subsequent tests or treatments might be recommended?

An abnormal Adiponectin test result, especially one that indicates low adiponectin levels, might necessitate further tests such as blood glucose levels, Hemoglobin A1c, or lipid profile to assess the extent of metabolic disturbances. Treatments can range from lifestyle interventions focusing on diet and physical activity to medications targeting specific metabolic or cardiovascular issues.

How frequently should the Adiponectin test be performed?

The frequency of the Adiponectin test largely depends on the individual's health status and risk profile. If you're at higher risk for metabolic disturbances or cardiovascular disease, your healthcare provider might recommend regular monitoring. However, for individuals with no significant risk factors, frequent testing might not be necessary.

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.

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