All Bone and Joint Tests

The Bone Specific Alkaline Phosphatase Test evaluates levels of BSAP, an enzyme produced by osteoblasts during bone formation. Abnormal results may reflect osteoporosis, Paget’s disease, rickets, or other metabolic bone disorders. This test supports assessment of bone turnover, skeletal remodeling, and overall bone health, offering valuable information about metabolic activity in musculoskeletal function.

The QuestAssureD™ Vitamin D 25-Hydroxy Total Test measures Vitamin D2, Vitamin D3, and total 25-hydroxy vitamin D to assess overall vitamin D status. Adequate vitamin D supports bone strength, calcium absorption, immune health, and muscle function. Low levels may cause osteoporosis, weakness, or increased disease risk, while high levels can indicate toxicity. Doctors use this test to diagnose deficiency, monitor supplementation, and evaluate metabolic and endocrine health.

The Vitamin D 1,25-Dihydroxy Test measures the active form of vitamin D in blood to evaluate calcium and phosphorus balance, bone health, and kidney function. Abnormal levels may indicate kidney disease, parathyroid disorders, or problems with calcium metabolism. Doctors order this test when deficiency symptoms don’t match 25-hydroxy vitamin D results or to monitor chronic illness. Results provide vital insight into vitamin D activity, mineral health, and metabolic function.

The C-Reactive Protein (CRP) Test measures CRP levels in blood to detect inflammation in the body. Elevated CRP may indicate infections, autoimmune disorders, or chronic diseases such as arthritis, cardiovascular disease, or inflammatory bowel disease. Doctors use this test to assess acute illness, monitor treatment response, and evaluate risk for heart disease. The CRP test provides key insight into inflammation, immune health, and overall wellness.

The Calcium Micronutrient Test measures calcium levels in the blood to assess nutritional status and detect imbalances. Calcium is essential for strong bones and teeth, muscle contraction, nerve signaling, and heart function. This test helps identify deficiencies, excess, or issues with absorption and metabolism, supporting diagnosis and management of bone health, hormonal balance, and overall wellness.

Patient must be 18 years of age or older.

The Calcium Test measures calcium levels in blood to assess bone health, parathyroid function, and metabolic balance. Abnormal levels may indicate bone disease, parathyroid disorders, kidney disease, or certain cancers. Both low and high calcium can cause muscle spasms, weakness, or irregular heartbeat. Doctors order this test to monitor osteoporosis, kidney stones, or endocrine disorders. Results provide essential insight into bone, nerve, and overall metabolic health.

The Heavy Metals Micronutrients Blood Test Panel measures levels of arsenic, cadmium, cobalt, lead, and mercury to assess exposure and potential toxicity. These metals, found in the environment, food, or workplaces, can affect the nervous system, kidneys, bones, and overall health. This panel helps detect harmful accumulation, guide treatment, and monitor risks from environmental or occupational exposure.

Patient must be 18 years of age or older.

The Calcium 24 Hour Urine with Creatinine Test evaluates calcium excretion alongside creatinine to provide insight into kidney health, mineral balance, and bone metabolism. Elevated or low calcium may reflect kidney stones, parathyroid disease, osteoporosis, or metabolic disorders. This test supports monitoring of calcium regulation, renal function, and systemic conditions linked to skeletal health.

The Comprehensive Metabolic Panel (CMP) Test measures 21 markers to assess metabolic health, liver and kidney function, and electrolyte balance. It includes glucose, calcium, sodium, potassium, chloride, CO2, albumin, globulin, A/G ratio, total protein, bilirubin, ALP, AST, ALT, BUN, creatinine, BUN/creatinine ratio, and eGFR. The CMP helps detect diabetes, liver or kidney disease, and supports routine screening and chronic condition monitoring.

The Complete Blood Count with Differential and Platelets Test is a comprehensive blood test that checks red blood cells, white blood cells, hemoglobin, hematocrit, and platelets. The differential analyzes types of white blood cells to detect infections, anemia, clotting abnormalities, immune conditions, and certain cancers. This essential test is often ordered for routine health exams, diagnosis, and monitoring treatment progress.

The Rheumatoid Factor (RF) Test measures RF antibodies in blood to help diagnose rheumatoid arthritis and other autoimmune conditions. High RF levels may indicate rheumatoid arthritis, Sjögren’s syndrome, or other connective tissue diseases, though they can also appear in some infections. Doctors order this test to investigate joint pain, stiffness, or swelling. Results provide important insight into autoimmune activity, joint health, and inflammatory disease management.

The Collagen Cross-Linked N-Telopeptide (NTx) 24 Hour Urine Test measures breakdown products of type I collagen, the main protein in bone. Elevated levels reflect increased bone resorption, which may be linked to osteoporosis, metabolic bone disease, or treatment monitoring. This test provides valuable insight into bone turnover, helping evaluate bone health, response to therapy, and risk of skeletal disorders.

The Collagen Cross-Linked N-Telopeptide Urine Test measures type I collagen breakdown products to evaluate bone resorption and skeletal health. Elevated levels may indicate osteoporosis, metabolic bone disease, or increased bone turnover, while lower levels may reflect treatment response. This test provides insight into bone metabolism, helping clinicians assess risk of fractures, monitor therapy, and track long-term bone health.

The Collagen Type I C-Telopeptide (CTX) Test measures CTX fragments released during bone breakdown, making it a key marker of bone resorption. Elevated levels may indicate osteoporosis, metabolic bone disease, or increased fracture risk. Doctors order this test to monitor bone loss, evaluate treatment for osteoporosis, or assess bone health in postmenopausal women. Results provide vital insight into bone turnover and long-term skeletal health management.

The Estradiol (E2) Test measures levels of estradiol, the primary form of estrogen, to evaluate reproductive and hormonal health. It helps assess menstrual irregularities, fertility issues, menopause status, and estrogen-producing disorders. In men, it aids in diagnosing hormonal imbalances. Doctors use the estradiol test to monitor hormone therapy, ovarian function, and conditions affecting puberty, bone health, and overall endocrine balance.

The Testosterone Free and Total Test measures total testosterone and free, bioavailable testosterone in blood for both men and women. It helps diagnose hormone imbalance, infertility, low libido, erectile dysfunction in men, irregular periods, or PCOS in women. Doctors also order it to assess fatigue, mood changes, or muscle weakness and to monitor hormone therapy. This test provides key insight into reproductive, endocrine, and overall metabolic health.

The Testosterone Free, Bioavailable, and Total Test measures total testosterone, free testosterone, and bioavailable testosterone, along with sex hormone binding globulin (SHBG) and albumin. This test provides a complete evaluation of hormone balance in men and women. Doctors use it to assess infertility, erectile dysfunction, low libido, PCOS, fatigue, or muscle loss and to monitor hormone therapy. Results offer key insight into reproductive, endocrine, and metabolic health.

The Testosterone Free and Total and Sex Hormone Binding Globulin (SHBG) Test measures total testosterone, free testosterone, and SHBG to assess hormone balance in men and women. It helps diagnose infertility, erectile dysfunction, low libido, irregular periods, PCOS, and abnormal puberty. Doctors also use it to evaluate fatigue, muscle weakness, or mood changes and to monitor hormone therapy. This test provides a comprehensive view of reproductive, endocrine, and metabolic health.

The Testosterone Total Male Test measures testosterone levels in men to assess reproductive, sexual, and hormonal health. It helps diagnose low testosterone (hypogonadism), infertility, and erectile dysfunction. Doctors use it to evaluate fatigue, muscle loss, or low libido and to monitor testosterone therapy, hormonal balance, bone health, and overall metabolism.

Patient must be male and 18 years of age or older.

The T4 Total Test measures total thyroxine (T4) in blood, a combination of both bound and unbound (free) T4, to assess thyroid function. Abnormal levels may indicate hypothyroidism, hyperthyroidism, goiter, or pituitary disorders. Doctors use this test to evaluate symptoms like fatigue, weight changes, hair loss, or irregular heart rate and to monitor thyroid replacement or antithyroid therapy. The T4 Total Test provides key insight into metabolic, hormonal, and endocrine health.

The Serum Protein Electrophoresis (SPEP) Test separates proteins in blood into albumin and globulin fractions to detect abnormal patterns. Doctors order this test to evaluate multiple myeloma, Waldenström’s macroglobulinemia, amyloidosis, or chronic infections. Abnormal results may indicate monoclonal gammopathy or immune disorders. Results provide essential insight into protein balance, immune function, and blood-related cancers, guiding diagnosis and monitoring.

The Iron Total and Total Iron Binding Capacity (TIBC) Test measures iron levels in blood along with the blood’s ability to transport iron. It helps diagnose iron deficiency anemia, iron overload (hemochromatosis), and monitor nutritional or chronic health conditions. Low iron or high TIBC may indicate anemia, while high iron or low TIBC can suggest overload. Doctors use this test to evaluate fatigue, weakness, or other symptoms linked to iron and metabolic health.

The Bilirubin Direct Test measures conjugated bilirubin in the blood to assess liver function and bile duct health. Elevated levels may indicate hepatitis, cirrhosis, gallstones, or bile duct obstruction, while low levels are generally normal. Doctors order this test for patients with jaundice, fatigue, or suspected liver disease. Results help diagnose and monitor liver disorders, guide treatment decisions, and evaluate overall hepatic and biliary health.