Reproductive Hormones

Our reproductive hormone blood test checks the levels of your reproductive hormones to determine if they are out of balance.

Are you concerned about reproductive hormones imbalance? Read below to find out about the benefits of reproductive hormone lab tests!


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17-hydroxyprogesterone is elevated in patients with congenital adrenal hyperplasia (CAH). CAH is a group of autosomal recessive diseases characterized by a deficiency of cortisol and an excess of ACTH concentration. 17-hydroxyprogesterone is also useful in monitoring cortisol replacement therapy and in evaluating infertility and adrenal and ovarian neoplasms.

17-ketosteroids can be used as indicators of adrenal and testicular and to a lesser extent the ovarian function.

Determination of ACTH is useful in differentiating between primary and secondary adrenocortical hypo- and hyperfunctional disorders: Addison's disease, Cushing's syndrome, adrenal carcinoma, ectopic ACTH syndrome, and adrenal nodular hyperplasia.

Determination of aldosterone is useful in the diagnosis and evaluation of primary aldosteronism, selective hypoaldosteronism, edematous states, and other conditions of electrolyte imbalance

Approximately 1-2% of individuals with primary hypertension have primary hyperaldosteronism characterized by hypokalemia (low potassium) and low direct renin. Because serum aldosterone concentrations vary due to dietary sodium intake and body position, some physicians prefer measurement of 24-hour urine concentration for aldosterone.

The Aldosterone-renin ratio is used to screen for primary aldosteronism

Androstenedione is useful when evaluating patients with androgen excess and managing patients with Congenital Adrenal Hyperplasia (CAH).


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Cortisol is increased in Cushing's Disease and decreased in Addison's Disease (adrenal insufficiency). Patient needs to have the specimen collected between 7 a.m.-9 a.m.


Deoxycorticosterone (DOC) is a weak mineralocorticoid derived from 21-hydroxylation of progesterone in the adrenal cortex.

DHEA is a weakly androgenic steroid that is useful when congenital adrenal hyperplasia is suspected. It is also useful in determining the source of androgens in hyperandrogenic conditions, such as polycystic ovarian syndrome and adrenal tumors.

DHEA-S is the sulfated form of DHEA and is the major androgen produced by the adrenal glands. This test is used in the differential diagnosis of hirsute or virilized female patients and for the diagnosis of isolated premature adrenarche and adrenal tumors. About 10% of hirsute women with polycystic ovarian syndrome (PCOS) have elevated DHEA-S but normal levels of other androgens.

DHEA-S is the sulfated form of DHEA and is the major androgen produced by the adrenal glands. This test is used in the differential diagnosis of hirsute or virilized female patients and for the diagnosis of isolated premature adrenarche and adrenal tumors. About 10% of hirsute women with Polycystic Ovarian Syndrome (PCOS) have elevated DHEA-S but normal levels of other androgens.


DHT is a potent androgen derived from testosterone via 5-alpha-reductase activity. 5-alpha-reductase deficiency results in incompletely virilized males (phenotypic females). This diagnosis is supported by an elevated ratio of testosterone to DHT.


Elevated levels of serum erythropoietin (EPO) occur in patients with anemias due to increased red cell destruction in hemolytic anemia and also in secondary polycythemias associated with impaired oxygen delivery to the tissues, impaired pulmonary oxygen exchange, abnormal hemoglobins with increased oxygen affinity, constriction of the renal vasculature, and inappropriate EPO secretion caused by certain renal and extrarenal tumors. Normal or depressed levels may occur in anemias due to increased oxygen delivery to tissues, in hypophosphatemia, and in polycythemia vera.

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Measuring the circulating levels of estradiol is important for assessing the ovarian function and monitoring follicular development for assisted reproduction protocols. Estradiol plays an essential role throughout the human menstrual cycle. Elevated estradiol levels in females may also result from primary or secondary ovarian hyperfunction. Very high estradiol levels are found during the induction of ovulation for assisted reproduction therapy or in pregnancy. Decreased estradiol levels in females may result from either lack of ovarian synthesis (primary ovarian hypofunction and menopause) or a lesion in the hypothalamus-pituitary axis (secondary ovarian hypofunction). Elevated estradiol levels in males may be due to increased aromatization of androgens, resulting in gynecomastia.

IMPORTANT - Note this Estradiol test is not for children that have yet to start their menstrual cycle.  If this test is ordered for a child that has yet to begin their menstrual cycle Quest Diagnostics labs will substitute in Estradiol, Ultrasensitive LC/MS/MS - #30289 at an additional charge of $34


Estradiol and Testosterone Total contains the following tests.

  • Estradiol
  • Testosterone, Total, LC/MS/MS

IMPORTANT - Note the Estradiol test included in this panel is not for children that have yet to start their menstrual cycle.  If this test is ordered for a child that has yet to begin their menstrual cycle Quest Diagnostics labs will substitute Estradiol, Free, LC/MS/MS at an additional fee of $290.00


Much of Estradiol is bound to proteins. The unbound portion and Estradiol bound to proteins with low affinity reflect the Free concentration. The Free Estradiol may better correlate with medical conditions than the Total Estradiol concentrations.


Estradiol, FSH and Testosterone Free and Total panel contains the following test.

  • Estradiol
  • FSH (Follicle Stimulating Hormone)
  • Testosterone, Free (Dialysis) and Total LC/MS/MS

Estradiol, FSH, SHBG, Testosterone Free and Total Panel contains the following tests:

  • Estradiol
  • FSH (Follicle Stimulating Hormone)
  • Sex Hormone Binding Globulin (SHBG)
  • Testosterone, Free (Dialysis) and Total LC/MS/MS


Estrogens are a group of steroids that regulate the menstrual cycle and function as the main female sex hormones. The most common forms of estrogens tested are estrone (E1), estradiol (E2), and estriol (E3). Estrogens are responsible for the development of female sex organs and secondary sex characteristics and are tied to the menstrual cycle and pregnancy. They are considered the main sex hormones in women and are present in small quantities in men. E1 and E2 are the two main estrogens in non-pregnant females.Estrone (E1) is derived from metabolites from the adrenal gland and is often made in adipose tissue (fat). Estrone can be converted into estrdiol or estriol when needed. Estrone is present in small amounts in children prior to puberty and then increases slightly at puberty for both males and females. While levels remain constant in adult males, it will increase and fluctuate for females during the menstrual cycle. After menopause, it becomes the major estrogen, with E2 and E3 levels diminishing greatly.Estradiol (E2) is the predominant form and is produced primarily in the ovaries with additional amounts produced by the adrenal glands in women and in the testes and adrenal glands in men. In menstruating women, levels vary throughout the month, rising and falling in concert with FSH (follicle-stimulating hormone), LH (luteinizing hormone), and progesterone as follicles are stimulated in the ovaries, an egg is released, and the uterus prepares for a potential pregnancy. The level is lowest at the beginning of the menstrual cycle and rise to their highest level just before the release of an egg from the ovary (ovulation). Normal levels of estradiol provide for proper ovulation, fertilization of the egg (conception), and pregnancy, in addition to promoting healthy bone structure and regulating cholesterol levels.


The placenta converts DHEA-S produced by the fetal adrenals to Estriol and other estrogens. Estriol is useful in assessing the fetal adrenals and placenta during pregnancy. More commonly, Estriol is one of the maternal serum biochemical markers used to screen for common chromosomal trisomies, especially Down syndrome.


Reproductive hormones do more than just affecting your fertility. These hormones are responsible for causing symptoms such as abnormal hair growth, balding, and mood swings. If you are currently experiencing any of these symptoms, you should consider a reproductive hormone lab test to see your reproductive hormone levels. It helps determine if you need hormone replacement therapy. Whether you plan to conceive soon or not, you should have the right balance of reproductive hormones in your body. Keep reading this article to learn more about how reproductive hormones affect your body and whether it is time for you to get a reproductive hormone test.

Reproductive Hormone Imbalance

An imbalance of reproductive hormones in your body can cause various problems over time. Reproductive hormones include:

Reproductive hormone imbalance differs according to its symptoms and outcomes. Here are four major types of reproductive hormone imbalances and their effect on your bod

  • Menopause symptoms
  • Ovarian insufficiency
  • Low testosterone in men
  • Polycystic Ovarian Syndrome

Hormonal imbalances affect both men and women. 

Reproductive Hormonal Imbalance - Risk Factor

The actual cause of reproductive hormone imbalance is still not known. Hence, it's difficult to state what kinds of activities put people at a greater risk for developing such a condition. But current research reveals a few trends in people suffering from reproductive hormone imbalances, such as:

  • Being overweight
  • Older age
  • Little to no exercise
  • Poor diet
  • Living in toxic environments
  • High levels of stress

These risks are simply trends in the patient population that suffers from reproductive hormonal imbalances, but they do not determine if someone has a hormonal imbalance. If you think you have a hormonal imbalance, you should talk to your healthcare provider even if any one of these qualities doesn't describe your condition. 

The Causes of Reproductive Hormone Imbalance

There are different types of reproductive hormone imbalances out there. Each imbalance starts with the endocrine system, but the actual causes of the imbalance are mostly unknown. Some researchers believe that reproductive hormone imbalances are autoimmune in nature. But some others think that the individuals' diet and environment have much to do with the condition. It's hard to pinpoint a specific cause for the condition since research is still ongoing. 

Symptoms Of Reproductive Hormone Imbalance

There are multiple symptoms of reproductive hormonal imbalance. The imbalance can result in too much or too little of a reproductive hormone, and the patient's symptoms will reflect the lack or excess of the reproductive hormone that is out of balance. Some patients may have hot flashes, while some may have chills when they suffer from the condition. On the other hand, some patients can be hungry all the time, while others may not be hungry at all. The symptoms depend on which hormone is out of balance.

When the ovaries don't properly develop, it will result in ovarian insufficiency syndrome. This can occur due to the lack of proper endocrine signaling or an autoimmune problem. Due to the fertility problems that result from this syndrome, the condition is also known as premature menopause. The ovaries get damaged due to radiation or chemotherapy. That is why women who go through radiation or chemotherapy treatments cannot conceive after the treatments.

Damaged ovaries cause an imbalance of estrogen and progesterone in the system of the patient. It may lead to a myriad of symptoms, including:

  • Hot flashes
  • Dry eyes
  • Vaginal dryness
  • Decreased sex drive
  • Night sweats
  • Irritability
  • Difficulty concentrating

Menopause is considered another type of hormonal imbalance, but it's completely normal to go through menopause. Estrogen and progesterone levels in the patient's body will be quite low during menopause. However, hormone replacement therapy will help some patients avoid the symptoms that come with this condition.

Polycystic ovarian syndrome (PCOS) is a condition that produces high testosterone levels in the female body. Testosterone is the primary male reproductive hormone. Symptoms of excess amounts of male hormones in a woman's body can include:

  • Infertility
  • Acne
  • Oily Skin
  • Excess body hair
  • Missed or irregular periods
  • Ovarian cysts
  • Large ovaries
  • Male-pattern baldness

The condition can also result in diabetes, insulin resistance, and cardiovascular diseases. Although some experts believe that PCOS is an autoimmune condition of the endocrine system, it still hasn't been proven. 

Symptoms of low testosterone levels in men include:

  • Weakness
  • Infertility
  • Low energy
  • Decreased sex drive
  • Slower metabolism
  • Low bone density

Similar to hormonal imbalances in women, male imbalances should be identified and treated as soon as possible. 

Lab Tests to Diagnose Reproductive Hormone Imbalances

Lab work is important to determine whether you have a hormonal imbalance or not. Luckily, Ulta Lab Tests offers a wide range of lab tests to check if you have a reproductive hormone imbalance. Our lab tests will look at the testosterone, estrogen, progesterone, and other hormone levels in your body. By measuring the levels of hormones in your body, you can see whether or not you have a hormone imbalance. 

If your test results determine that you have a reproductive hormone imbalance, you should talk to your healthcare provider immediately. Your physician will perform an evaluation to determine what could be causing your hormone imbalance and develop an appropriate treatment plan for your condition.

Order your hormone lab tests with Ulta Lab Tests

If you notice signs of reproductive hormone imbalances, you should act fast. Hormone imbalances will become worse when left untreated. Ulta Lab Tests provides highly accurate and reliable lab tests to make informed decisions about your health. Here are some of the reasons why people loving using Ulta Lab Tests:

  • No health insurance required
  • Secure and confidential results
  • Affordable pricing on all tests
  • No need for a physician's referral
  • 100% satisfaction guarantee 
  • Results are available in 24-48 hours for most tests

Take control of your health and well-being by ordering your hormone lab tests from Ulta Lab Tests.