Liver Health

A liver function panel is a group of tests performed to detect, evaluate, and monitor liver disease or damage. Order yours today from Ulta Lab Tests and get your results confidentially online in 24 to 48 hours.


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Serum alkaline phosphatase levels are of interest in the diagnosis of hepatobiliary disorders and bone disease associated with increased osteoblastic activity. Moderate elevations of alkaline phosphatase may be seen in several conditions that do not involve the liver or bone. Among these are Hodgkin's disease, congestive heart failure, ulcerative colitis, regional enteritis, and intra-abdominal bacterial infections. Elevations are also observed during the third trimester of pregnancy.


This assay is intended for use in the assessment of risk for the development of hepatocellular carcinoma (HCC) in patients with chronic liver disease.


An increase in serum bile acids concentration in the fasting state or postprandial is considered to be a specific indicator of liver disease. A decreased level indicates bile acid malabsorption, possibly due to ileal dysfunction.

Measurement of the levels of bilirubin is used in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gall bladder obstructive disease

Measurement of the levels of bilirubin is used in the diagnosis and treatment of liver, hemolytic, hematologic, and metabolic disorders, including hepatitis and gallbladder obstructive disease.

The BUN/Creatinine ratio is useful in the differential diagnosis of acute or chronic renal disease. Reduced renal perfusion, e.g., congestive heart failure, or recent onset of urinary tract obstruction will result in an increase in BUN/Creatinine ratio. Increased urea formation also results in an increase in the ratio, e.g., gastrointestinal bleeding, trauma, etc. When there is decreased formation of urea as seen in liver disease, there is a decrease in the BUN/Creatinine ratio. In most cases of chronic renal disease the ratio remains relatively normal.

Increased CRP levels are found in inflammatory conditions including: bacterial infection, rheumatic fever, active arthritis, myocardial infarction, malignancies and in the post-operative state. This test cannot detect the relatively small elevations of CRP that are associated with increased cardiovascular risk.

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A large percentage of patients with gastrointestinal tumors (such as pancreatic, liver, gastric, colorectal tumors) and some other malignancies have been shown to have elevated serum CA 19-9 levels. Serum CA 19-9 levels may be useful for monitoring disease activity or predicting relapse following treatment. CA 19-9 should not be used as a screening test.

Low levels of fibrinogen are associated with bleeding most commonly secondary to liver disease or disseminated intravascular coagulation (DIC). Fibrinogen is an acute phase reactant and thus elevated levels may be associated with inflammation. Increased concentrations are also associated with increased risk of atherosclerosis.

Serum Triglyceride analysis has proven useful in the diagnosis and treatment of patients with diabetes mellitus, nephrosis, liver obstruction, other diseases involving lipid metabolism, and various endocrine disorders. In conjunction with high density lipoprotein and total serum cholesterol, a triglyceride determination provides valuable information for the assessment of coronary heart disease risk.

Measurement of serum 25-OH vitamin D concentrations provide a good index of circulating vitamin D activity in patients not suffering from renal disease. Lower than normal 25-OH vitamin D levels can result from a dietary deficiency, poor abosrption of the vitamin or impaired metabolism of the sterol in the liver. A 25-OH vitamin D deficiency can lead to bone diseases such as rickets and osteomalacia. Above normal levels can lead hypercalcemia. This assay employs liquid chromatography tandem mass spectrometry to independently measure and report the two common forms of 25-hydroxy vitamin D: 25OH D3 - the endogenous form of the vitamin and 25OH D2 - the analog form used to treat 25OH Vitamin D3 deficiency.

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Increased serum CEA levels have been detected in persons with primary colorectal cancer and in patients with other malignancies involving the gastrointestinal tract, breast, lung, ovarian, prostatic, liver and pancreatic cancers. Elevated serum CEA levels have also been detected in patients with nonmalignant disease, especially patients who are older or who are smokers. CEA levels are not useful in screening the general population for undetected cancers. However, CEA levels provide important information about patient prognosis, recurrence of tumors after surgical removal, and effectiveness of therapy.

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Decreased levels of ceruloplasmin are found in Wilson''s Disease, fulminant liver failure, intestinal malabsorption, renal failure resulting in proteinuria, chronic active hepatitis and malnutrition. Elevated levels are found in primary biliary cirrhosis, pregnancy (first trimester), oral contraceptive use and in acute inflammatory conditions since ceruloplasmin is an acute phase reactant

CH50 is a screening test for total complement activity. Levels of complement may be depressed in genetic deficiency, liver disease, chronic glomerulonephritis, rheumatoid arthritis, hemolytic anemias, graft rejection, systemic lupus erythematosis, acute glomerulonephritis, subacute bacterial endocarditis and cryoglobulinemia. Elevated complement may be found in acute inflammatory conditions, leukemia, Hodgkin's Disease, sarcoma, and Behcet's Disease.

A Complete Blood Count (CBC) Panel is used as a screening test for various disease states including anemia, leukemia and inflammatory processes.

A CBC blood test includes the following biomarkers: WBC, RBC, Hemoglobin, Hematocrit, MCV, MCH, MCHC, RDW, Platelet count, Neutrophils, Lymphs, Monocytes, Eos, Basos, Neutrophils (Absolute), Lymphs (Absolute), Monocytes(Absolute), Eos (Absolute), Basos (Absolute), Immature Granulocytes, Immature Grans (Abs)


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The DCP assay is intended for in vitro diagnostic use as an aid in the risk assessment of patients with chronic liver disease for progression to hepatocellular carcinoma (HCC) in conjunction with other laboratory findings and clinical assessment.

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Useful in the diagnosis of hypochromic, microcytic anemias. Decreased in iron deficiency anemia and increased in iron overload.


Low levels of fibrinogen are associated with bleeding most commonly secondary to liver disease or Disseminated Intravascular Coagulation (DIC). Fibrinogen is an acute phase reactant and thus elevated levels may be associated with inflammation. Increased concentrations are also associated with increased risk of atherosclerosis.

Elevated GGT is found in all forms of liver disease. Measurement of GGT is used in the diagnosis and treatment of alcoholic cirrhosis, as well as primary and secondary liver tumors. It is more sensitive than alkaline phosphatase, the transaminases, and leucine aminopeptidase in detecting obstructive jaundice, cholangitis, and cholecystitis. Normal levels of GGT are seen in skeletal diseases; thus, GGT in serum can be used to ascertain whether a disease, suggested by elevated alkaline phosphatase, is skeletal or hepatobiliary.

Includes

Hepatitis A Antibody, Total; Hepatitis B Surface Antibody, Qualitative; Hepatitis B Surface Antigen with Reflex Confirmation; Hepatitis B Core Antibody, Total; Hepatitis C Antibody with Reflex to HCV, RNA, Quantitative, Real-Time PCR

Hepatitis B Surface Antigen with Reflex Confirmation: Positive samples will be confirmed based on the manufacturer's FDA approved recommendations at an additional charge (CPT code(s): 87341).


If Hepatitis C Antibody is reactive, Hepatitis C Viral RNA, Quantitative, Real-Time PCR will be performed at an additional charge (CPT code(s): 87522).


Serum iron quantification is useful in confirming the diagnosis of iron-deficiency anemia or hemochromatosis. The measurement of total iron binding in the same specimen may facilitate the clinician''s ability to distinguish between low serum iron levels caused by iron deficiency from those related to inflammatory neoplastic disorders. The assay for iron measures the amount of iron which is bound to transferrin. The total iron binding capacity (TIBC) measures the amount of iron that would appear in blood if all the transferrin were saturated with iron. It is an indirect measurement of transferri

Lactate Dehydrogenase (LD) (LDH)

Elevations in serum lactate dehydrogenase occur from myocardial infarction, liver disease, pernicious and megaloblastic anemia, pulmonary emboli, malignancies, and muscular dystrophy



The liver is one of the most important organs in the human body. It serves many important roles, from aiding the digestion of food and liquids to filtering harmful toxins from the blood. It also creates important proteins and plays a part in hundreds of functions throughout the body.

With all of this being the case, it's important the liver remains healthy. It's also important to find out as soon as possible when it isn't working as it should. This can be done through a hepatic function panel and other lab tests relating to liver health.

There are several different things that can cause issues with the liver. This article will take a look at possible signs and symptoms of liver damage, who's at risk, and what you can do to assess liver damage.

What Is Liver Health Decline?

Liver health decline refers to a negative change in the liver's ability to function correctly. There can be many reasons a person's liver can become damaged or go into decline. 

Hepatitis A, B, and C are inflammatory conditions of the liver. A person can contract these diseases in a number of different ways, from viral infections to adverse reactions to drugs or alcohol. Abuse of alcohol can also lead to liver diseases such as cirrhosis.

Hemochromatosis is another common liver disease. People suffering from this condition store too much iron in their bodies, which can cause damage to several organs, including the liver. It is thought to be hereditary.

Other genetic liver diseases include Wilson's disease and Alpha-1 antitrypsin deficiency. Cancer of the liver is another common liver disease.

Risk Factors for Liver Health Decline

Genetics can play a part in liver health decline. If a direct relative has suffered from any of the above genetic liver diseases, you may be at greater risk of contracting them.

Other factors that can put you at higher risk of liver health decline include lifestyle-related elements such as obesity, alcohol abuse, intravenous drug use, unprotected sex, Type 2 diabetes, and exposure to certain toxins.

Signs and Symptoms of Liver Health Decline

If you're worried you may be at risk of suffering from liver health decline, there are a number of signs and symptoms to observe. Jaundice is one of the most prominent signs of liver damage. This is when the skin takes on a yellowish hue; the whites of your eyes may also appear yellow.

Darkened urine can also be a sign your liver is not functioning as it should. If your urine is consistently appearing amber or brown in color, this is cause for concern. This occurs due to the liver's inability to break down a chemical compound known as bilirubin.

Other common symptoms include abdominal swelling, pale-colored stools, nausea, fatigue, easily bruising skin, and swollen legs or ankles. If you are experiencing one or more of the above symptoms for a prolonged period, you may want to investigate further by conducting a liver health test.

How Is Liver Health Decline Diagnosed?

There are a number of tests that can be carried out to determine how well your liver is functioning. A hepatic function panel is a comprehensive range of tests to assess the overall health of the liver. Because a hepatic (liver) panel is comprised of many different measurements, there is no one defined list of the tests it entails.

However, the measurements most often taken in the course of a liver function panel are:

  • Aspartate aminotransferase: AST is an enzyme that helps to process proteins
  • Alanine aminotransferase: ALT is another enzyme found in the liver that assists in the function of the metabolism
  • Alkaline phosphatase: ALP is an enzyme found in the liver, as well as bones, and other tissues in the body
  • Bilirubin: bilirubin is a yellow-colored waste product created during the breakdown of red blood cells
  • Albumin: a protein produced by the liver that prevents fluids from leaking out of the bloodstream

Then there are other tests that can also be conducted to detect indicators of poor liver health. Levels of the enzyme gamma-glutamyltransferase (GGT) may be tested, as high levels can be a sign of bile duct damage.

Another measurement that is often taken is levels of lactate dehydrogenase (LD). Elevated levels of this enzyme may indicate liver damage or a range of other disorders.

Prothrombin time (PT) is often also checked. PT is the time it takes your blood to clot. A high PT can be a sign of liver damage.

Other more general tests that can also pick up signs of liver damage include a C-reactive protein test, a complete blood count with differential and platelets blood test, and a comprehensive metabolic panel. Iron and total iron-binding capacity may also be checked.

As well as diagnosing liver decline, many of these tests are conducted to monitor liver diseases after they are diagnosed.

Frequently Asked Questions About Liver Health Decline and Lab Testing

Below are some common questions regarding liver health decline and methods for testing liver function.

How Common Is Liver Health Decline?

Liver damage and decline are on the rise. They are more common in white and Native American people and more common in men than in women.

How Are Tests Conducted?

Blood tests assess liver function. A phlebotomist will take your blood and send your sample to a lab to be assessed.

How Fast Will I Get My Results?

In the majority of cases, you will receive your results online between 24 and 48 hours after your test.

Liver Function Panel and Liver Health Lab Tests

If you're concerned about the health of your liver, consider taking a liver function panel or other liver health lab tests today. With Ulta Lab tests, you'll receive quick and confidential results without the need for health insurance or a doctor's referral.

Tests are affordable and you get a 100% satisfaction guarantee. Take control of your health today with Ulta Lab Tests.