Respiratory

Respiratory tests identify the germs that cause cough, sore throat, fever, runny nose, and shortness of breath. Because these symptoms overlap among influenza, COVID-19, RSV, strep throat, pertussis, atypical bacteria, and common cold viruses, lab testing helps you and your clinician make clear decisions.

A proactive approach pairs pathogen detection (rapid antigen and molecular NAAT/RT-PCR, throat and sputum cultures, urine antigens) with inflammation and safety labs (procalcitonin, CRP, CBC, basic chemistries). Use single-virus tests when you already suspect the cause, or a multiplex panel when several viruses are circulating. These tests support screeningdiagnosis, and monitoring, but they do not replace a clinician’s exam, chest imaging, or emergency care for severe symptoms.

Signs, Symptoms & Related Situations

  • Upper airway: sore throat, hoarse voice, runny/stuffy nose, sinus pressure, ear pain

  • Lower airway: cough (dry or productive), wheeze, shortness of breath, chest tightness

  • Systemic: fever/chills, fatigue, headaches, body aches

  • Exposure & season: known contact, school/daycare or workplace outbreaks, peak flu/RSV/COVID-19 periods, travel

  • Higher-risk groups: adults ≥65, infants/young children, pregnancy, chronic heart/lung/kidney disease, diabetes, immune suppression, residents of long-term care

  • Seek urgent care now: severe trouble breathing, bluish lips/face, chest pain, confusion, fainting, signs of dehydration, or symptoms that rapidly worsen

Symptoms require evaluation by a qualified clinician.

Why These Tests Matter

What testing can do

  • Confirm the cause (viral vs. bacterial) to guide next steps and isolation decisions

  • Differentiate among flu, COVID-19, RSV, strep throat, pertussis, and atypical bacteria

  • Track severity and trends with procalcitonin/CRP and CBC

What testing cannot do

  • Replace chest X-ray/CT, oxygen checks, or a physical exam when indicated

  • Prove a diagnosis from a single late or early sample—timing and specimen quality matter

  • Provide treatment or dosing advice—that belongs with your clinician

What These Tests Measure (at a glance)

  • Rapid Antigen (point-of-care): quick detection of influenza A/BSARS-CoV-2RSV, and Group A Strep; best in the first 3–4 days of symptoms. Less sensitive than molecular tests.

  • Molecular NAAT/RT-PCR: highly sensitive detection of viral RNA/DNA (e.g., flu A/B, SARS-CoV-2, RSV, adenovirus, rhinovirus, metapneumovirus, parainfluenza) and some atypicals (Mycoplasma pneumoniaeBordetella pertussis).

  • Multiplex Respiratory Panels: one swab tests for multiple viruses ± atypical bacteria—useful when several pathogens circulate or for higher-risk patients.

  • Throat Tests: rapid strep antigen/NAAT and throat culture for Group A Streptococcus.

  • Sputum Gram Stain & Culture: identifies bacterial causes of lower-respiratory infection and provides susceptibilities; sample quality matters.

  • Blood Cultures (×2 sets): check for bloodstream infection in moderate–severe illness; draw before antibioticswhen possible.

  • Urine Antigens: rapid tests for Streptococcus pneumoniae and Legionella pneumophila.

  • Procalcitonin (PCT): higher in many bacterial infections; trends help more than one value.

  • C-Reactive Protein (CRP) & ESR: inflammation markers supporting severity assessment.

  • CBC with Differential & BMP/CMP: white-cell patterns, electrolytes, kidney/liver function for overall status and safety.

Quick Build Guide

Clinical goal Start with Add if needed
New respiratory illness, early Rapid antigen (flu/COVID/RSV or strep) Molecular NAAT/RT-PCR if negative but suspicion is high
Higher-risk or severe symptoms Molecular NAAT/RT-PCR (± multiplex) • CBC • CRP/PCT • BMP Blood cultures • Urine antigens • Sputum culture if productive
Strep throat evaluation Rapid strep antigen or NAAT Throat culture if negative but suspicion remains
Persistent cough / atypical pattern Respiratory PCR (include Mycoplasmapertussis if available) Sputum culture or targeted atypical testing
Facility/household outbreak Rapid antigen for triage Multiplex PCR to confirm circulating pathogens

How the Testing Process Works

  1. Choose your test: select single-pathogen tests when the likely cause is clear, or multiplex when several viruses are possible.

  2. Prepare for accuracy: avoid heavy nasal sprays just before swabbing; provide a deep-cough sputum sample if asked. No fasting is required.

  3. Provide the sample: anterior nasal, mid-turbinate, or nasopharyngeal swab for most tests; throat swab for strep; sputum for lower-airway cultures; blood/urine for specific markers.

  4. Result timing: many antigen tests are same-day; molecular and culture results typically post in 1–3 days.

  5. Review in context: combine results with exam and (when indicated) chest imaging to decide on isolation, return-to-work, or further care.

Interpreting Results (General Guidance)

  • Positive viral PCR or antigen: supports a viral cause (flu, COVID-19, RSV, etc.); coinfections can occur—review with your clinician.

  • Positive Group A Strep test: consistent with strep throat; throat culture confirms when needed.

  • Bacterial growth on sputum culture: identifies a bacterial pathogen and guides therapy via susceptibilities.

  • High or rising procalcitonin: favors bacterial infectionfalling values often align with recovery.

  • Negative results, strong suspicion: consider repeat or alternate testing; specimen timing/quality can affect accuracy.
    Always interpret results with a qualified healthcare professional.

Choosing Panels vs. Individual Tests

  • Targeted answer: Rapid antigen or single-virus PCR (flu, COVID-19, RSV) or rapid strep for sore throat.

  • Broader answer: Multiplex PCR panel when several pathogens are possible, for high-risk patients, or for program requirements.

  • Severe/complicated cases: add sputum/blood culturesurine antigens, and PCT/CRP to build a fuller picture.

FAQs

Do I need to fast?
No. Respiratory tests use swabs (and sometimes blood or urine), with no fasting required.

Is PCR better than antigen?
PCR/NAAT is more sensitiveantigen is faster. Early in illness, antigen can be helpful; negative antigen with strong suspicion often needs PCR.

Can one swab test flu, COVID-19, and RSV?
Yes. A multiplex panel can test several viruses from a single sample.

Will a flu or COVID-19 vaccine cause a positive test?
No. Vaccines do not make viral diagnostic tests positive.

How soon should I test after symptoms start?
As soon as possible—ideally within 3–4 days. Molecular tests can detect a bit later than antigen tests.

What if my tests are negative but I’m getting worse?
Seek clinical care. You may need repeat testingimaging, or evaluation for other conditions.

Are home tests acceptable?
Some programs accept them; others require laboratory testing. Follow your employer/school policy.

Related Categories & Key Tests

  • Infectious Disease Tests Hub

  • Influenza Tests • COVID-19 Tests • RSV Tests • Pneumonia Tests • Strep Throat Tests • TB & QuantiFERON • Immunity & Titer Tests

  • Key Tests: Rapid Antigen (Flu/COVID/RSV/Strep) • Molecular NAAT/RT-PCR (single or multiplex) • Throat Culture • Sputum Gram Stain & Culture • Urine Antigen—Streptococcus pneumoniae • Urine Antigen—Legionella • Procalcitonin • CRP • CBC with Differential • BMP/CMP • Blood Cultures

References

  • Centers for Disease Control and Prevention — Respiratory virus testing overviews and clinical considerations.
  • Infectious Diseases Society of America — Guidance for influenza, COVID-19, Group A Streptococcus, and community-acquired pneumonia diagnostics.
  • American Thoracic Society — Pneumonia guidelines and specimen quality standards.
  • World Health Organization — Laboratory testing principles for respiratory infections.
  • Clinical and Laboratory Standards Institute — Best practices for respiratory specimen collection and handling.

Available Tests & Panels

Your Respiratory Tests menu is pre-populated in the Ulta Lab Tests system. Choose targeted rapid antigen or single-virus PCR when you know what you’re looking for, or select a multiplex panel to test several pathogens at once. Add strep testingsputum/blood culturesurine antigens, and PCT/CRP/CBC as needed. Follow collection instructions and review results with your clinician to plan isolation, documentation, and follow-up.

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Phlebotomist

The Alpha-1 Antitrypsin Random Feces Test measures levels of alpha-1 antitrypsin, a protein that normally remains in the bloodstream. Elevated amounts in stool suggest protein-losing enteropathy, intestinal inflammation, or gastrointestinal conditions that impair absorption. By evaluating protein loss through the digestive tract, this test helps assess intestinal integrity and overall digestive health.

Varied
Phlebotomist
Also Known As: Alpha-1 Antitrypsin Test, A1AT Test, AAT Test, Alpha-1 Antitrypsin Feces Test

The Alpha-1-Antitrypsin Quantitative Test measures levels of alpha-1-antitrypsin (AAT), a protein that protects the lungs and liver from damage. Low levels may indicate alpha-1-antitrypsin deficiency, a genetic disorder linked to emphysema, COPD, and liver disease. Doctors use this test to investigate unexplained lung or liver problems, confirm hereditary AAT deficiency, and guide treatment or monitoring strategies for long-term health management.

Blood
Blood Draw
Also Known As: Alpha-1 Antitrypsin Test, A1AT Test, AAT Test, Alpha-1 Antitrypsin Serum Test

The Bordetella pertussis Toxin IgG Antibody Test measures IgG antibodies to pertussis toxin, helping determine prior exposure or vaccination response to whooping cough. Elevated IgG suggests immunity from infection or vaccination, while low levels may indicate susceptibility. Doctors use this test to confirm immune status, assess protection in healthcare workers or students, and guide vaccination decisions for preventing pertussis outbreaks.


The Bordetella Pertussis Toxin IgG IgA Antibodies Test measures immune response to pertussis toxin, detecting both IgG and IgA antibodies. IgG indicates prior infection or vaccination, while IgA reflects more recent mucosal response. This test aids in evaluating immunity, identifying recent or past exposure, and supporting diagnosis of whooping cough, an acute respiratory infection caused by Bordetella pertussis.

Blood
Blood Draw

The Complete Blood Count with Differential and Platelets Test is a comprehensive blood test that checks red blood cells, white blood cells, hemoglobin, hematocrit, and platelets. The differential analyzes types of white blood cells to detect infections, anemia, clotting abnormalities, immune conditions, and certain cancers. This essential test is often ordered for routine health exams, diagnosis, and monitoring treatment progress.

Blood
Blood Draw
Also Known As: CBC Test, CBC with Differential and Platelets Test, CBC w/Diff and Platelets Test, Full Blood Count Test, Complete Blood Count Test

The Comprehensive Metabolic Panel (CMP) Test measures 21 markers to assess metabolic health, liver and kidney function, and electrolyte balance. It includes glucose, calcium, sodium, potassium, chloride, CO2, albumin, globulin, A/G ratio, total protein, bilirubin, ALP, AST, ALT, BUN, creatinine, BUN/creatinine ratio, and eGFR. The CMP helps detect diabetes, liver or kidney disease, and supports routine screening and chronic condition monitoring.

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Blood Draw
Also Known As: CMP Test, Chemistry Panel Test, Chem Test, Chem 21 Test, Chem 14 Test 

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Blood Draw

The Haemophilus influenzae type B IgG Antibody Test measures IgG levels against Hib bacteria to evaluate immune protection. Adequate antibody levels reflect vaccine response or past exposure, while low levels may indicate susceptibility to infection. This test supports assessment of immune status in children, immunocompromised patients, or individuals at risk for invasive Hib disease such as meningitis or pneumonia.

Blood
Blood Draw

The Hypersensitivity Pneumonitis Screen detects IgG precipitins to inhaled antigens—such as Aspergillus fumigatus, Micropolyspora faeni, and pigeon serum—to support evaluation of hypersensitivity pneumonitis. Positive precipitins help identify antigen sensitization linked to interstitial lung inflammation and guide further diagnostic workup.

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Most Popular

The Immunoglobulin E (IgE) Test measures IgE antibody levels in blood to evaluate allergic reactions, asthma, and immune response. Elevated IgE may indicate allergies to food, pollen, or other triggers, as well as eczema or parasitic infections. Doctors order this test to investigate symptoms like hives, sneezing, or wheezing and to guide allergy treatment. Results provide vital insight into immune health, allergic sensitivity, and overall diagnostic care.

Blood
Blood Draw
Also Known As: Immunoglobulin E Test, Immunoglobulin E Antibody Test, IgE Antibody Test

Most Popular

The Immunoglobulin G (IgG) Test measures IgG antibody levels in blood to assess immune system function and long-term response to infections. Low IgG may indicate immune deficiencies or recurrent infections, while high levels may signal chronic inflammation, autoimmune disease, or certain infections. Doctors use this test to evaluate unexplained illness, monitor immune disorders, or assess overall immunity. Results provide vital insight into immune health and disease management.

Blood
Blood Draw
Also Known As: Immunoglobulin G Test, Immunoglobulin G Antibody Test, IgG Antibody Test

Most Popular

The Immunoglobulin M (IgM) Test measures IgM antibody levels in blood to evaluate immune response and early defense against infections. High IgM may indicate recent or acute infections, autoimmune disease, or certain blood disorders, while low levels may suggest immune deficiency. Doctors order this test to investigate recurrent infections, unexplained inflammation, or suspected immune problems. Results provide vital insight into antibody health, immune status, and diagnostic care.

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Blood Draw
Also Known As: Immunoglobulin M Test, Immunoglobulin M Antibody Test, IgM Antibody Test

Most Popular

The Immunoglobulin A (IgA) Test measures IgA antibody levels in blood to evaluate immune system health and mucosal defense in the respiratory and digestive tracts. Low IgA may indicate immune deficiency, celiac disease, or recurrent infections, while high levels may suggest autoimmune disorders, liver disease, or chronic inflammation. Doctors use this test to assess unexplained illness or immune imbalance. Results provide key insight into antibody function and overall immunity.

Blood
Blood Draw
Also Known As: Immunoglobulin A Test, Immunoglobulin A Antibody Test, IgA Antibody Test

The Mycoplasma pneumoniae IgG IgM Antibodies Test detects antibodies to M. pneumoniae, a common cause of respiratory infections and “walking pneumonia.” IgM indicates recent or active infection, while IgG suggests past exposure or immunity. Doctors use this blood test to confirm diagnosis, distinguish between current and previous infection, and guide treatment. It is especially helpful for evaluating persistent cough, fever, or suspected atypical pneumonia.

Also Known As: Mycoplasma Antibodies Test, M. pneumoniae Test, Mycoplasma Test, Mycoplasma IgG IgM Test

The Mycoplasma pneumoniae IgG Antibody Test measures IgG antibodies to M. pneumoniae, the bacterium responsible for atypical or “walking” pneumonia. Elevated IgG levels indicate prior infection or past exposure, helping distinguish recent illness from long-term immunity. This test aids in evaluating respiratory conditions, guiding diagnosis of atypical pneumonia, and supporting differentiation from viral or bacterial lung infections.

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Varied
Phlebotomist

The QuantiFERON-TB Gold Plus Test is a blood test that detects latent or active tuberculosis (TB) infection by measuring the immune response to TB antigens. It offers greater accuracy than the traditional skin test and avoids false positives from prior BCG vaccination. Doctors use it for TB screening, diagnosis, and monitoring in high-risk individuals. The QFT-Plus test is recommended for healthcare workers, travelers, and those exposed to TB.

Blood
Blood Draw
Also Known As: TB Test, Tuberculosis Test, IGRA Test

The Streptococcus pneumoniae Antigens Urine Test detects pneumococcal antigens in urine to help diagnose infections caused by Streptococcus pneumoniae, including community-acquired pneumonia and invasive pneumococcal disease. This rapid, noninvasive test aids in early detection and clinical management of bacterial respiratory and systemic infections.

Urine
Urine Collection

The 14 Serotypes Streptococcus Pneumoniae IgG Antibody Panel evaluates IgG antibodies to key pneumococcal serotypes linked to invasive infections. This test helps identify immune competence, detect possible deficiencies, and assess vaccine effectiveness. It offers valuable information for patients with frequent sinus or respiratory infections, chronic lung disease, or suspected impaired immunity. Clinicians use results to guide prevention and treatment strategies.

Blood
Blood Draw
Also Known As: 14 Serotypes Streptococcus Pneumoniae Antibody Panel

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Blood Draw

Most Popular

The QuantiFERON®-TB Gold Plus (QFT-Plus) Test is a modern blood test that detects tuberculosis infection, including latent and active TB. Unlike the traditional skin test, it does not require a return visit and provides highly specific results by measuring interferon-gamma release in response to TB antigens. Physicians use this test to screen high-risk individuals, confirm TB exposure, and guide timely treatment decisions for better patient outcomes.

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Blood Draw

The West Nile Virus IgG IgM Antibodies Test measures immune response to West Nile virus, distinguishing recent from prior infection. IgM levels indicate active or recent illness, while IgG reflects past exposure or long-term immunity. This test aids in evaluating unexplained fever, flu-like symptoms, or neurological complications, supporting assessment of vector-borne viral infection and systemic health.

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Blood, Urine
Blood Draw, Urine Collection

Did you know almost 37 million people in the United States live with chronic respiratory diseases like chronic obstructive pulmonary disease (COPD) or bronchitis?

Acute respiratory disease and infectious respiratory diseases also cause ongoing health problems for millions more in America. For this reason, respiratory lab tests are an essential tool for the treatment and management of respiratory diseases.

You can catch many respiratory diseases through the air that can impact your respiratory system. If you want to learn more about respiratory disease and respiratory testing, keep reading this guide to learn everything you need to know.

What Is Respiratory Disease?

There are different types of respiratory disease, both acute and chronic. Acute respiratory infections are usually infectious caused by viruses and bacteria that can affect you anywhere in the respiratory system.

Acute respiratory infections are especially dangerous for children, older adults, and anybody with problems with their immune system. Causes of acute respiratory symptoms include:

  • The common cold
  • Ear infections
  • Throat infections
  • Bronchitis
  • Pneumonia

Usually, people with acute respiratory infections have fatigue, body aches, and chest congestion.

Chronic Respiratory Disease

One of the most common types of chronic respiratory disease is asthma. When asthma flares up, it causes wheezing, coughing, and chest tightness. It's not known exactly why some people get asthma, and others don't, but the belief is that genetics play a role. 

Another common chronic respiratory disease is chronic obstructive pulmonary disease (COPD) which occurs when your lungs become inflamed. This inflammation leads to difficulty breathing, thickening of the lining of your lungs, and an overproduction of mucus.

Emphysema is another chronic respiratory disease that damages the air sacs in your lungs. When your lungs are healthy, the air sacs are strong, but emphysema weakens these sacs causing them to rupture.

Lung Cancer

Lung cancer is cancer that starts in your lungs. There are two main types of lung cancer, based upon how the cells appear under a microscope. The two main types include:

  • Small cell lung cancer usually occurs from heavy smoking
  • Non-small cell lung cancer is a term for all other types of lung cancer

If you smoke, you have the greatest risk of getting lung cancer, yet some people develop lung cancer that has never smoked. Even if you've been smoking for a long time, you can still quit and significantly reduce your chances of developing lung cancer.

Risk factors for Respiratory Disease

There are different risk factors for both acute and chronic respiratory disease. Risk factors for acute respiratory disease include:

  • Smoking
  • Poor hygiene
  • Chronic medical conditions
  • Old age
  • Stress and poor mental health

Risk factors for chronic respiratory disease have a lot to do with the environment you live in. Risk factors include:

  • Smoking
  • Second-hand smoke
  • Outdoor air pollution
  • Indoor air pollution

Certain allergens and occupational risks include working with chemicals, dust, and fumes regularly.

Causes of Respiratory Disease

There are many causes of respiratory disease, depending on the type. Respiratory disease is most often caused by a bacteria, virus, or fungal infection. 

Other respiratory diseases like asthma and lung cancer can be associated with asbestos exposure and air pollution. Other causes include:

  • Smoking
  • A genetic condition called Alpha-1 Deficiency 
  • A history of numerous respiratory infections during childhood
  • Breathing in secondhand smoke frequently

Sometimes radon, an orderless gas present in many homes, can contribute to the development of lung cancer. 

Signs and Symptoms of Respiratory Diseases

Most of the time, symptoms of a respiratory problem don't stick around for long, but there are symptoms you need to pay attention to, such as:

  • A cough that becomes chronic, lasting more than eight weeks
  • Shortness of breath at rest or with exercise
  • Wheezing
  • Coughing up blood
  • Ongoing chest pain
  • Fever
  • Coughing up a lot of phlegm
  • Not being able to cough up congestion

You should see your doctor right away if you're concerned about any respiratory symptoms you're having, especially if you feel shortness of breath and chest pain.

Diagnosis of Respiratory Disease

Your doctor will first ask you questions about your past medical history and current symptoms and then a physical exam. Your doctor will pay close attention while listening to your lungs and order tests to assess your lung function.

A pulmonary function test is a noninvasive test that measures your lung volume, capacity, flow, and how well you exchange gas. This is a great test to give an overall picture of how well your lungs are working.

An arterial blood gas test is usually done in a hospital and involves directly measuring your blood's oxygen and carbon dioxide levels. Blood is taken directly from an artery in your wrist to do this test, where your pulse is usually taken.

Other tests like a chest x-ray, CT scan, or ultrasound of your chest are also done to check the structure of your heart and lungs. Blood tests are also ordered to check for things like infections and antibody levels.

Lab Tests for Respiratory Disease

One of the first tests you'll have is a complete blood count (CBC), which measures your red blood cells and will detect if your white blood cells are elevated, which is a sign of infection.

comprehensive metabolic panel is an important test to understand your electrolyte balance, liver and kidney health, and blood sugar levels.

Alpha-1-antitrypsin is used to test for a genetic problem in the alpha-1-antitrypsin (AAT) protein. This protein is a protectant for the lungs, and if they are not the right shape, they get stuck in the liver and never reach the lungs.

An ANA screen tests for autoimmune diseases like lupus and scleroderma, which can affect your lungs. A c-reactive protein lab will test for inflammation from infections, autoimmune disease, or a heart attack.

FAQS about Respiratory Disease

Have you ever wondered if there is a cure for asthma? The answer is no, there is no cure, but asthma can be effectively managed so you can live a full life. Being mindful of avoiding allergens and asthma triggers, as well as using your inhalers for immediate relief, are the best things you can do.

What is mesothelioma? Mesothelioma is a rare type of cancer that is caused by prolonged exposure to asbestos. Asbestos is an insulating material that used to be used in building construction, but it was later found to cause cancer.

Tests for Infectious Respiratory Diseases

Ulta Lab Tests offers highly accurate tests, allowing you to make informed decisions about your health. 

Here are a few things to love about Ulta Lab Tests:

  • You get secure and confidential results
  • No need for health insurance
  • No need for a physician's referral
  • Always affordable pricing
  • A 100% satisfaction guarantee

Respiratory diseases are serious and can lead to chronic health problems. Order your infectious respiratory disease test today, and you'll get secure online results in 24 to 48 hours in most cases.

Take charge of your health and visit Ulta Lab Tests today!

As the name suggests, norovirus is a virus.  It causes an infection in the digestive tract.  This infection will often irritate the stomach and intestines, gastroenteritis, and is often incorrectly thought to be a stomach bug or the stomach flu. There are many common symptoms of the norovirus, including diarrhea, nausea, sudden stomach pain, and vomiting. 

The norovirus is extremely contagious and will spread through ingesting contaminated liquids or foods, touching contaminated surfaces, and coming into close contact with infected people.  Those who are contagious may spread the virus for much longer than they are actually ill with it.  This is due to norovirus being present in the stool before signs and symptoms are exhibited, and for up to two weeks after the person starts to feel better. 

The CDC (or the Centers for Disease Control) believes that norovirus affects approximately 20 million people in the US each year.  This makes it the most common cause of food poisoning in the country.  It is also considered the most common cause of acute diarrhea in healthy adults. 

As norovirus can rapidly spread, outbreaks in college dorms, daycare centers, schools, nursing homes, cruise ships, and other places where food is served, and people stay in close contact can occur.  People who live in these settings are at a higher risk of catching this virus.  

Drinking and eating in a place where food handling procedures are unsanitary is another common cause of infections.   

Anyone can become infected, but most people will recover in a few days.  However, the elderly, young children, and people who have underlying health conditions and weakened immune systems, can have further problems.  The infection can cause serious complications such as severe dehydration that can be fatal if not treated.  After being infected, people do not become immune and can be re-infected multiple times throughout their lives.   

The Symptoms 

People who have been infected by the norovirus will start to show signs within 12 to 48 hours following exposure.  The symptoms of this virus will last for one to three days on average.  Some of the common symptoms and signs include: 

  • Nausea 
  • Diarrhea 
  • Fever 
  • Body aches 
  • Stomach pain 
  • Vomiting 
  • Headache 

As the norovirus causes diarrhea and vomiting several times a day, it can easily lead to dehydration.  The signs of dehydration include less frequent urination, dizziness, and dry mouth.  Dehydration can be dangerous to the elderly, young children, and people who have underlying medical conditions. 

Laboratory Testing 

Usually, norovirus is diagnosed clinically, by considering the person’s signs and symptoms, the severity and duration of the symptoms, and what the person has recently eaten. 

Laboratory testing is not usually performed except if the person has a higher risk for complication from infections or if the symptoms may be part of a broader outbreak, may be caused by a different condition with the same type of symptoms, are severe and/or last more than a few days. 

If public health authorities suspect an outbreak, testing may be conducted to figure out whether it is norovirus or another microbe causing the illness.   Also, testing may be implemented to manage/contain outbreaks or to track cases and their locations. 

Infected people who are at a higher risk for complications and those with severe illness should have a stool sample analyzed in a laboratory.  There is a range of tests that can be used to diagnose norovirus and rule out any other type of infection. 

Gastrointestinal pathogens panels will look for multiple gastrointestinal microbes that cause disease and show in stool samples.  

Individual molecular tests, including PT-PCR, will look specifically for norovirus in the stool sample.  These are the preferred tests for diagnosing any norovirus infection. 

Stool culture tests will look for several bacterial pathogens that are common, including Shigella and Salmonella.  These infections can cause symptoms that are similar to the norovirus.   

Stool WBC (or white blood cells), as the name suggests, looks at the number of white blood cells in the stool, which can be an indicator of infection from parasites and bacteria.  People who are infected with norovirus will generally not have these cells in their stool. 

O&P (or ova and parasite exam) is done to rule out any potential parasite infections because the symptoms of these infections are similar to the norovirus.  This is a good test for anyone who had traveled internationally before their symptoms appeared. 

FOBT (or fecal occult blood test) is ordered in cases where bloody diarrhea occurs and identifies the illness causing the bloody stool.  Occult blood will not be present in a stool that has norovirus.   

There are other general tests that will also be performed should someone become very ill.  This includes when a person suffers from dehydration and a high fever.   

Blood cultures are sometimes ordered to rule out any bacterial infections which spread into the blood. 

BMP (or basic metabolic panel) is a test panel used to monitor potassium and sodium as well as acid-based imbalances in people who suffer from severe dehydration to ensure proper organ function. 

CBC (or complete blood count) is a panel that is sometimes ordered to determine if there is an increase in white blood cells pointing to bacterial infections. 

Preventing Norovirus 

To protect against getting this highly contagious virus and the accompanying infection, a person should: 

  • Thoroughly wash hands often, especially after handling diapers or using the restroom and prior to handling or eating food. 
  • Stay away from contaminated food and water, and food prepared by someone who has, or has recently had, norovirus. 
  • Cook seafood thoroughly and wash vegetables and fruits. 

People who have had recent norovirus infection should: 

  • Use a chlorine bleach solution to disinfect virus-contaminated surfaces. 
  • Stay at home – don’t go to work and avoid other activities, especially food handling. 
  • Keep sick children at home. 
  • Avoid traveling until signs and symptoms have passed and keep washing hands. 

Treating Norovirus 

Like many food and waterborne illnesses, norovirus does not usually require treatment beyond supportive care like drinking fluids and resting.  The symptoms will often go away within a few days in otherwise healthy people. 

Antibiotics are not effective because norovirus is not a type of bacteria. People older than 65 may be prescribed anti-diarrheal medication.  Intravenous fluids may be required in cases of severe symptoms and significant dehydration, along with hospitalization.