The Bordetella pertussis toxin (PT) Antibody (IgG), Im test contains 1 test with 1 biomarker.
Brief Description: The Bordetella pertussis toxin IgG Antibody test is a laboratory test used to detect and measure the presence of specific antibodies in the blood that are produced in response to an infection or vaccination against the bacteria Bordetella pertussis. This bacteria is the causative agent of pertussis, commonly known as whooping cough, a highly contagious respiratory disease.
Collection Method: Blood Draw
Specimen Type: Serum
Test Preparation: No preparation required
When and Why the Bordetella pertussis toxin IgG Antibody Test May be Ordered
Healthcare providers may order the Bordetella pertussis toxin IgG Antibody test:
- To confirm a recent or past infection of pertussis in a patient, especially in cases where the clinical symptoms are suggestive of whooping cough.
- To determine if someone has gained immunity against pertussis through vaccination or previous infection.
- In the case of an outbreak, to ascertain who might have been exposed or is potentially immune.
What the Bordetella pertussis toxin IgG Antibody Test Checks For
This test specifically checks for the presence and levels of IgG antibodies against the toxin produced by Bordetella pertussis. If the body has been exposed to the bacteria, either through infection or vaccination, it produces these antibodies as a part of its immune response.
Other Lab Tests Ordered Alongside the Bordetella pertussis toxin IgG Antibody Test
When suspecting pertussis or examining the immune status against the bacteria, doctors might also order:
- Bordetella pertussis culture: This involves taking a sample from the back of the throat (using a swab) and trying to grow the bacteria in the lab to confirm its presence.
- Bordetella pertussis PCR (Polymerase Chain Reaction): A rapid test to detect the genetic material of the bacteria.
- Complete Blood Count (CBC): To check for an elevated white blood cell count, which is common in whooping cough.
Conditions or Diseases that Require the Bordetella pertussis toxin IgG Antibody Test
The primary condition that would necessitate this test is:
- Pertussis (Whooping Cough): Characterized by severe coughing fits followed by a "whooping" sound during the intake of breath. The condition is especially severe and can be fatal in infants.
Usage of Bordetella pertussis toxin IgG Antibody Test Results by Health Care Providers
Healthcare providers interpret the results as follows:
Positive Result: Indicates that the patient has been exposed to Bordetella pertussis either through infection or vaccination. If the patient has clinical symptoms consistent with whooping cough and tests positive, it's likely a recent infection.
Negative Result: Suggests that the patient hasn't been exposed to the bacteria or that the exposure was too recent for antibodies to have developed (as it can take 1-2 weeks post-exposure for antibodies to appear).
Doctors use the results in conjunction with clinical symptoms and other laboratory findings to diagnose, manage, and potentially treat pertussis. If used for public health reasons during an outbreak, the results can also guide vaccination or prophylaxis strategies.
Most Common Questions About the Bordetella pertussis toxin IgG Antibody test:
Purpose and Indications for the Bordetella pertussis toxin IgG Antibody Test
Why is the Bordetella pertussis toxin IgG Antibody test ordered?
The Bordetella pertussis toxin IgG Antibody test is typically ordered when there's a suspicion that an individual has been infected with the bacteria responsible for whooping cough, which is Bordetella pertussis. Detecting IgG antibodies specific to the toxin helps confirm a past infection or determine immunity status.
What does the Bordetella pertussis toxin IgG Antibody test help diagnose?
The test helps diagnose whooping cough, or pertussis, especially in cases where symptoms are prolonged or atypical. While other tests can detect active infections, the IgG antibody test can indicate a past infection or successful vaccination.
Interpreting the Results
What do positive results in the Bordetella pertussis toxin IgG Antibody test indicate?
A positive result indicates that the individual has IgG antibodies against Bordetella pertussis toxin, suggesting either a past infection or a response to the vaccine. It implies immunity against the bacteria, although immunity might wane over time.
How is the Bordetella pertussis toxin IgG Antibody test result used alongside other diagnostic tests for pertussis?
The Bordetella pertussis toxin IgG Antibody test provides information about past exposure or vaccination. For diagnosing an active infection, a culture or PCR test for Bordetella pertussis would be more appropriate. Together, these tests give a comprehensive picture of a patient's pertussis status.
Follow-up and Treatment
If the Bordetella pertussis toxin IgG Antibody test results are positive, but the person has never shown symptoms, what does it mean?
A positive result in someone without symptoms might mean they were asymptomatically infected in the past or that they have received a pertussis vaccine. The antibodies are an immune response to either the natural infection or the vaccine.
How do results from the Bordetella pertussis toxin IgG Antibody test influence vaccination recommendations?
Positive results indicating immunity might mean that a booster vaccine is not immediately needed. However, given that immunity to pertussis wanes over time, periodic boosters are typically recommended, especially for certain populations like healthcare workers or those in contact with infants.
Disease Monitoring and Complications
Can the Bordetella pertussis toxin IgG Antibody test be used to monitor the effectiveness of a vaccine?
Yes, the test can be used to monitor the immune response after vaccination. A detectable level of IgG antibodies post-vaccination suggests an effective immune response. However, the level of antibodies will decline over time, which is why boosters are needed.
We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.