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The Complement Total CH50 Test measures overall activity of the complement system, a key part of the immune response that helps fight infections and regulate inflammation. Abnormal results may indicate autoimmune diseases such as lupus, complement deficiencies, or immune complex disorders. Doctors use this blood test to evaluate immune function, investigate recurrent infections, and monitor treatment in patients with suspected immune or autoimmune conditions.
The Complement Component C3c and C4c Test measures levels of two key proteins in the complement system, which supports immune defense and inflammation control. Abnormal results may indicate autoimmune disease, lupus, rheumatoid arthritis, or certain infections. Doctors use this test to investigate unexplained inflammation, monitor disease activity, and guide treatment decisions in patients with suspected immune or inflammatory disorders.
The Complement Component C3c Test measures levels of C3c, a protein involved in the immune complement system. Abnormal results may indicate autoimmune disorders, recurrent infections, or kidney disease linked to immune activity. Doctors use this blood test to evaluate complement activation, diagnose immune-related conditions, and monitor disease progression or treatment effectiveness in patients with suspected lupus, glomerulonephritis, or other immune disorders.
The Complement Component C4c Test measures blood levels of C4c, a protein in the complement system that supports immune defense and inflammation control. Abnormal levels may indicate autoimmune disorders such as lupus, rheumatoid arthritis, or immune complex disease, as well as certain kidney conditions. Doctors use this test to evaluate complement activation, confirm diagnosis, and monitor treatment response in patients with suspected immune-related diseases.
A comprehensive immune system evaluation measuring Complement C3, C4, and total hemolytic complement (CH50). This test helps assess complement pathway function, autoimmune disease activity, kidney inflammation, and potential complement deficiencies. Ideal for investigating immune dysregulation, recurrent infections, and systemic inflammatory conditions.
The Coccidioides Antibody Complement Fixation and Immunodiffusion Test measures antibody response to fungal infection caused by Coccidioides species. It helps distinguish active from past infection, evaluate immune activity, and monitor disease progression. This test provides valuable information for assessing Valley Fever, systemic fungal disease, and complications involving the lungs, skin, or other organs.
Comprehensive autoimmune screening panel including ANA with reflex to titer and pattern, dsDNA, SS-A, SS-B, Scl-70, RNP, Sm antibodies, complement C3, C4, CH50, and Rheumatoid Factor. Designed to support evaluation of systemic autoimmune and connective tissue disorders with clinically relevant, disease-specific biomarkers.
The Inflammation, Autoimmune & Chronic Pain Comprehensive Lab Panel includes 46 tests and 158 biomarkers to support broad review of inflammation, autoimmune patterns, lupus-related markers, rheumatoid arthritis markers, antiphospholipid antibodies, Sjögren’s, celiac-related immune markers, thyroid autoimmunity, chronic joint and muscle pain, kidney and urine health, nutrients, omega status, and metabolic inflammation markers.
The Inflammation, Autoimmune & Chronic Pain Advanced Lab Panel includes 41 tests and 138 biomarkers to support deeper review of inflammation, autoimmune screening, lupus-related markers, rheumatoid arthritis markers, Sjögren’s antibodies, celiac-related immune patterns, thyroid autoimmunity, chronic joint and muscle pain, kidney and urine health, nutrients, methylation, recovery, and metabolic inflammation markers.
The Direct Antiglobulin Test with Reflex to Anti C3 and Anti IgG evaluates immune-mediated red blood cell destruction by detecting antibodies or complement proteins. Abnormal findings may suggest autoimmune hemolytic anemia, drug-induced hemolysis, or transfusion reaction. Reflex testing helps distinguish complement activation from IgG involvement, offering insight into immune regulation and hematologic health.
The C3a DesArg Fragment Test measures levels of C3a desarginated, a stable breakdown product of complement activation. Elevated concentrations reflect immune system activation and may indicate autoimmune disease, sepsis, allergic reactions, or inflammatory conditions. This test provides insight into complement pathway activity, helping evaluate immune dysregulation, monitor disease progression, or assess systemic inflammation.
The DNA (ds) Antibody Test detects double-stranded DNA antibodies, often linked to systemic lupus erythematosus (SLE) and other autoimmune diseases. High levels may indicate lupus activity, kidney involvement, or autoimmune flare-ups. Doctors order this test for patients with joint pain, fatigue, rash, or suspected connective tissue disease. Results provide critical insight for diagnosing lupus, monitoring disease progression, and guiding treatment decisions.
The Sm and Sm/RNP Antibodies Test detects autoantibodies associated with systemic lupus erythematosus (SLE) and mixed connective tissue disease (MCTD). Sm antibodies are highly specific for lupus, while Sm/RNP antibodies appear in MCTD and sometimes overlap syndromes. Physicians use this test to support diagnosis, evaluate autoimmune activity, and guide monitoring alongside other clinical findings and laboratory markers.
