Inflammation, Autoimmune & Chronic Pain - Comprehensive Lab Panel
The Inflammation, Autoimmune & Chronic Pain Comprehensive Lab Panel includes 46 tests and 158 biomarkers to support broad review of inflammation, autoimmune patterns, lupus-related markers, rheumatoid arthritis markers, antiphospholipid antibodies, Sjögren’s, celiac-related immune markers, thyroid autoimmunity, chronic joint and muscle pain, kidney and urine health, nutrients, omega status, and metabolic inflammation markers.
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The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.
Also known as: Microalbumin Random Urine with Creatinine
Creatinine, Random Urine
Microalbumin
Microalbumin/Creatinine
Also known as: 6 bisphospate, Fructose-1
Aldolase
Legionella Antigen,
Also known as: ANA IFA Panel Comprehensive, Antinuclear Antibody, IFA Panel Comprehensive, FANA, IFA Panel Comprehensive, Fluorescent Antinuclear Antibody, IFA Panel Comprehensive
ANA Screen, IFA
Dna (Ds) Antibody
Scl-70 Antibody
Sjogren's Antibody (Ss-A)
Sjogren's Antibody (Ss-B)
Sm Antibody
Sm/Rnp Antibody
Also known as: Beta2Glycoprotein I Antibodies IgG IgA IgM
B2 Glycoprotein I (Iga)ab
B2 Glycoprotein I (IgG)ab
B2 Glycoprotein I (IgM)ab
Also known as: Bilirubin Fractionated
Bilirubin, Direct
Bilirubin, Indirect
Bilirubin, Total
Also known as: C-Reactive Protein, CReactive Protein CRP, CRP
C-REACTIVE PROTEIN
Also known as: C3 C4 Complement Ch50
Complement Component C3c
Complement Component C4c
Complement, Total (Ch50)
Also known as: Anti-Cardiolipin IgG, Cardiolipin Antibody IgG, Phospholipid Antibody, IgG
Cardiolipin Ab (IgG)
Also known as: Anti-Cardiolipin IgM, Cardiolipin Antibody IgM, Phospholipid Antibody, IgM
Cardiolipin Ab (IgM)
Also known as: CBC, CBC includes Differential and Platelets, CBC/PLT w/DIFF, Complete Blood Count (includes Differential and Platelets)
NOTE: Ulta Lab Tests provides CBC test results from Quest Diagnostics as they are reported. Often, different biomarker results are made available at different time intervals. When reporting the results, Ulta Lab Tests denotes those biomarkers not yet reported as 'pending' for every biomarker the test might report. Only biomarkers Quest Diagnostics observes are incorporated and represented in the final CBC test results provided by Ulta Lab Tests.
Absolute Band Neutrophils (Only Reported If Detected)
Absolute Basophils
Absolute Blasts (Only Reported If Detected)
Absolute Eosinophils
Absolute Lymphocytes
Absolute Metamyelocytes (Only Reported If Detected)
Absolute Monocytes
Absolute Myelocytes (Only Reported If Detected)
Absolute Neutrophils
Absolute Nucleated Rbc (Only Reported If Detected)
Absolute Promyelocytes (Only Reported If Detected)
Band Neutrophils (Only Reported If Detected)
Basophils
Blasts (Only Reported If Detected)
Eosinophils
Hematocrit
Hemoglobin
Lymphocytes
MCH
MCHC
MCV
Metamyelocytes (Only Reported If Detected)
Monocytes
MPV
Myelocytes (Only Reported If Detected)
Neutrophils
Nucleated Rbc (Only Reported If Detected)
Platelet Count
Promyelocytes (Only Reported If Detected)
RDW
Reactive Lymphocytes (Only Reported If Detected)
Red Blood Cell Count
White Blood Cell Count
Also known as: Celiac Panel
Immunoglobulin A
Interpretation
Tissue Transglutaminase
Tissue Transglutaminase
Also known as: CoQ10
Coenzyme Q10
Also known as: Chem 12, Chemistry Panel, Chemistry Screen, CMP, Complete Metabolic Panel, Comprehensive Metabolic Panel CMP, SMA 12, SMA 20
Albumin
Albumin/Globulin Ratio
Alkaline Phosphatase
Alt
AST
Bilirubin, Total
Bun/Creatinine Ratio
Calcium
Carbon Dioxide
Chloride
Creatinine
Egfr African American
Egfr Non-Afr. American
GFR-AFRICAN AMERICAN
GFR-NON AFRICAN AMERICAN
Globulin
Glucose
Potassium
Protein, Total
Sodium
Urea Nitrogen (Bun)
Also known as: CK (Total), CPK, CPK (Total), Creatine Kinase CK Total, Creatine Phosphokinase (CPK), Total CK
Creatine Kinase, Total
Also known as: ACPA, Anti-CCP, Anti-citrulline Antibody, Anti-cyclic Citrullinated Peptide, Anti-Cyclic Citrullinated Peptide (CCP) Antibody IgG, CCP, CCP Antibody, Citrullinated Peptide (CCP) IgG, Cyclic Citrullinated Peptide Antibody, Cyclic Citrullinated Peptide CCP Antibody IgG
Cyclic Citrullinated
CYSTATIN C
eGFR
Also known as: (dsDNA), Anti-DNA, DNA ds Antibody, Double-Stranded DNA Antibody, dsDNA, Native DNA
Dna (Ds) Antibody
Ferritin
Also known as: Factor I, Fibrinogen, Fibrinogen Activity Clauss
Fibrinogen Activity,
Also known as: Gamma Glutamyl Transferase GGT, Gamma-Glutamyl Transferase, Gamma-Glutamyl Transpeptidase, Gamma-GT, GGTP, GTP
Ggt
Also known as: A1c, Glycated Hemoglobin, Glycohemoglobin, Glycosylated Hemoglobin, HA1c, HbA1c, Hemoglobin A1c, Hemoglobin A1c HgbA1C, Hgb A1c
HEMOGLOBIN A1C
Also known as: Ankylosing Spondylitis, HLAB27 Antigen
Hla-B27 Antigen
Also known as: Homocysteine, Homocysteine Cardiovascular
HOMOCYSTEINE,
Also known as: C-Reactive Protein, Cardio CRP, Cardio hs-CRP, CRP, High Sensitivity CRP, High-sensitivity C-reactive Protein, High-sensitivity CRP, Highly Sensitive CRP, hsCRP, Ultra-sensitive CRP
Hs Crp
Also known as: Insulin (fasting)
Insulin
Also known as: Iron and TIBC, Iron and Total Iron Binding Capacity TIBC, TIBC
% Saturation
Iron Binding Capacity
Iron, Total
Also known as: Lactate Dehydrogenase LD, LDH
Ld
Drvvt Mix Interpretation
Drvvt Screen
Lupus Anticoagulant
Ptt-La Screen
Magnesium
Methylmalonic Acid
ARACHIDONIC ACID
ARACHIDONIC ACID/EPA
DHA
DPA
EPA
EPA+DPA+DHA
LINOLEIC ACID
OMEGA-3 TOTAL
OMEGA-6 TOTAL
OMEGA-6/OMEGA-3 RATIO
Also known as: Protein Total Random Urine with Creatini
Creatinine, Random Urine
Protein, Total, Random Ur
Protein/Creatinine Ratio
Vitamin D, 25-Oh, D2
Vitamin D, 25-Oh, D3
Vitamin D, 25-Oh, Total
Also known as: RF
Rheumatoid Factor
Also known as: ESR, SED RATE, Sed Rate by Modified Westergren ESR
Sed Rate By Modified
Selenium
Also known as: Sjgrens Antibodies SSA SSB, SS-A & SS-B
Sjogren's Antibody (Ss-A)
Sjogren's Antibody (Ss-B)
Also known as: Sm and SmRNP Antibodies
Sm Antibody
Sm/Rnp Antibody
Also known as: Free T4, FT4, T4 Free
T4, Free
Thyroglobulin Antibodies
Thyroid Peroxidase
Also known as: Thyroid Stimulating Hormone Test, Thyrotropin Test
TSH
Also known as: Serum Urate, UA
Uric Acid
Also known as: UA, Complete, Urinalysis UA Complete, Urine Analysis, Complete
Amorphous Sediment (Only Reported If Detected)
Appearance
Bacteria
Bilirubin
Calcium Oxalate Crystals (Only Reported If Detected)
Casts (Only Reported If Detected)
Color
Crystals (Only Reported If Detected)
Glucose
Granular Cast (Only Reported If Detected)
Hyaline Cast
Ketones
Leukocyte Esterase
Nitrite
Occult Blood
Ph
Protein
Rbc
Reducing Substances (Only Reported If Detected)
Renal Epithelial Cells (Only Reported If Detected)
Specific Gravity
Squamous Epithelial Cells
Transitional Epithelial (Only Reported If Detected)
Triple Phosphate Crystals (Only Reported If Detected)
Uric Acid Crystals (Only Reported If Detected)
WBC
YEAST (Only Reported If Detected)
Also known as: B12, B12 Vitamin, Cobalamin, Cyanocobalamin, Vitamin B12 Cobalamin
Vitamin B12
Also known as: B6, B6 Vitamin, Pyridoxal, Pyridoxal Phosphate, Pyridoxal Phosphate (PLP), Vitamin B6 Pyridoxal Phosphate
Vitamin B6
Also known as: ZN, Plasma
Zinc
The Inflammation, Autoimmune & Chronic Pain - Comprehensive Lab Panel panel contains 46 tests with 164 biomarkers .
Overview
The Inflammation, Autoimmune & Chronic Pain - Comprehensive Lab Panel is designed for people who want a broad lab-based review of biomarkers related to inflammation, autoimmune patterns, chronic pain, joint pain, muscle pain, fatigue, thyroid autoimmunity, celiac-related immune markers, kidney and urine involvement, nutrient status, omega fatty acid balance, and metabolic inflammation.
This panel includes 46 tests and 158 biomarkers to support provider-guided conversations about systemic inflammation, lupus-related markers, rheumatoid arthritis markers, Sjögren’s antibodies, antiphospholipid antibody patterns, celiac-related immune markers, muscle inflammation, thyroid autoimmunity, kidney risk, liver safety, iron status, B-vitamin status, vitamin D, magnesium, selenium, zinc, CoQ10, and omega fatty acid status.
This panel does not diagnose autoimmune disease, lupus, rheumatoid arthritis, Sjögren’s syndrome, celiac disease, thyroid disease, kidney disease, chronic pain syndromes, or muscle disease by itself. Results should be reviewed with a licensed healthcare provider and interpreted with symptoms, physical exam findings, medications, supplements, personal history, family history, and clinical context.
Why Order This Panel?
The Inflammation, Autoimmune & Chronic Pain - Comprehensive Lab Panel may be helpful for people who want a deeper look at overlapping biomarkers that may be discussed when inflammation, autoimmune symptoms, chronic pain, joint pain, muscle pain, fatigue, or recurring unexplained symptoms are present.
This panel may help provide insight into:
- General inflammation with CRP, hs-CRP, ESR, and fibrinogen
- Systemic autoimmune screening with ANA and related antibody markers
- Lupus-related markers, including dsDNA, Sm, Sm/RNP, complements, and urine markers
- Rheumatoid arthritis-related markers, including rheumatoid factor and CCP antibody
- Antiphospholipid antibody patterns
- Sjögren’s antibodies
- Celiac-related immune markers
- Muscle inflammation or muscle injury markers
- Thyroid function and thyroid autoimmunity
- Kidney filtration, urine albumin, urine protein, and urinalysis findings
- Liver and bile-flow markers
- Iron storage and iron availability
- Vitamin D, B12, B6, magnesium, zinc, selenium, CoQ10, and omega fatty acid status
- Blood sugar, insulin, and metabolic inflammation patterns
This Panel May Be Helpful For People With
- Chronic inflammation concerns
- Joint pain or stiffness
- Muscle aches or weakness
- Chronic pain with unclear cause
- Fatigue or low energy
- Brain fog or poor focus
- Morning stiffness
- Swelling, redness, or tenderness in joints
- Dry eyes or dry mouth
- Rashes or photosensitivity
- Numbness, tingling, or neuropathy-like symptoms
- Digestive symptoms with possible celiac or gluten-related concerns
- Thyroid symptoms or known thyroid antibodies
- Family history of autoimmune disease
- History of abnormal ANA, RF, CCP, CRP, ESR, or thyroid antibodies
- Kidney or urine findings that need follow-up
- Interest in a broad autoimmune and inflammation baseline
What This Panel Helps Evaluate
This panel helps evaluate selected biomarkers related to:
- General inflammation
- Autoimmune screening patterns
- Lupus-related markers
- Rheumatoid arthritis-related markers
- Sjögren’s antibody patterns
- Antiphospholipid antibody patterns
- Celiac-related immune patterns
- Muscle inflammation and muscle injury context
- Thyroid function and thyroid autoimmunity
- Kidney and urine involvement
- Liver and bile-flow context
- Iron status and blood health
- Nutrient and methylation status
- Omega fatty acid balance
- Metabolic inflammation
- Chronic pain and recovery context
Which Tier Is Right for Me?
Essential Lab Panel
The Inflammation, Autoimmune & Chronic Pain - Essential Lab Panel is best for people who want a focused first-step inflammation and chronic pain baseline. It typically reviews CBC, CMP, CRP, hs-CRP, ESR, ferritin, iron/TIBC, RF, CCP, TSH, Free T4, thyroid antibodies, vitamin D, B12, magnesium, uric acid, and urinalysis.
Choose Essential if you want an accessible starting point for inflammation, joint pain, thyroid overlap, iron status, nutrient status, and general wellness.
Advanced Lab Panel
The Inflammation, Autoimmune & Chronic Pain - Advanced Lab Panel is best for people who want deeper autoimmune and chronic pain context. It may add ANA, complements, dsDNA, Sjögren’s antibodies, Sm/SmRNP antibodies, celiac testing, CK, aldolase, cystatin C, urine albumin, urine protein, GGT, bilirubin, MMA, B6, homocysteine, zinc, selenium, A1c, insulin, LD, and CoQ10.
Choose Advanced if symptoms are persistent or if you want a broader review of autoimmune patterns, muscle pain, gut-immune markers, kidney/urine involvement, methylation, metabolic inflammation, and recovery markers.
Comprehensive Lab Panel
The Inflammation, Autoimmune & Chronic Pain - Comprehensive Lab Panel is the broadest option. It includes 46 tests and 158 biomarkers and adds premium markers for antiphospholipid antibody context, lupus anticoagulant evaluation, HLA-B27, fibrinogen, OMEGACHECK™, and broad autoimmune/chronic pain review.
Choose Comprehensive if you want the widest review of systemic inflammation, autoimmune screening, lupus-related markers, rheumatoid arthritis markers, antiphospholipid antibodies, Sjögren’s, celiac-related inflammation, HLA-B27 inflammatory back pain context, thyroid autoimmunity, kidney/urine involvement, muscle pain, nutrient deficiencies, omega status, and metabolic inflammation.
Tests Included and Why They Matter
Core Inflammation and Blood Health
C-Reactive Protein, CRP
CRP is a blood marker that can rise when inflammation is present.
This test is included because it provides broad inflammation context. CRP may be reviewed when symptoms include joint pain, swelling, infection-like symptoms, inflammatory flares, autoimmune concerns, or unexplained pain. CRP does not identify the cause of inflammation by itself, so it should be interpreted with ESR, hs-CRP, CBC, symptoms, history, and provider guidance.
hs-CRP
High-sensitivity C-reactive protein is a more sensitive form of CRP often used for low-grade inflammation and cardiometabolic risk context.
This test is included because chronic low-grade inflammation may overlap with pain, metabolic risk, cardiovascular wellness, fatigue, and systemic inflammatory patterns. It is useful alongside standard CRP because each may support a different clinical question.
Sed Rate by Modified Westergren, ESR
ESR is a broad inflammation marker.
This test is included because ESR can provide additional inflammation context, especially when autoimmune or chronic inflammatory patterns are being reviewed. ESR may change more slowly than CRP and should be interpreted with symptoms and other findings.
Fibrinogen Activity, Clauss
Fibrinogen is a clotting protein that can also reflect inflammatory activity.
This test is included because fibrinogen may provide additional inflammation and coagulation context in a premium autoimmune and chronic pain panel.
CBC, includes Differential and Platelets
The CBC evaluates red blood cells, white blood cells, hemoglobin, hematocrit, platelets, and white blood cell types.
This test is included because blood count patterns may provide context for anemia, infection clues, immune activity, platelet changes, inflammation, fatigue, and overall blood health.
Systemic Autoimmune and Connective Tissue Disease Context
ANA, IFA Panel Comprehensive
ANA testing evaluates antinuclear antibody patterns, often using an IFA method with additional interpretive context depending on the panel.
This test is included because ANA may provide systemic autoimmune screening context when symptoms suggest connective tissue disease, lupus, Sjögren’s, systemic sclerosis, mixed connective tissue disease, or related patterns.
ANA results should not be interpreted alone. Positive ANA findings can occur in people without autoimmune disease, so results should be reviewed with symptoms, exam findings, antibody subtests, and provider guidance.
DNA (ds) Antibody
Double-stranded DNA antibodies are often reviewed in lupus-related evaluations.
This test is included because dsDNA may provide lupus-related antibody context when symptoms, ANA findings, complement patterns, or urine findings suggest provider-guided autoimmune follow-up.
Sm and Sm/RNP Antibodies
Sm and Sm/RNP antibodies are connective tissue disease-related markers.
These tests are included because they may provide context for lupus-related and mixed connective tissue disease-related patterns. They should be interpreted with ANA, dsDNA, complements, symptoms, and provider guidance.
Sjögren’s Antibodies, SS-A and SS-B
SS-A and SS-B antibodies are commonly reviewed in Sjögren’s-related evaluations.
These tests are included because Sjögren’s-related patterns may overlap with dry eyes, dry mouth, fatigue, joint pain, neuropathy-like symptoms, and other systemic symptoms.
C3, C4, Complement CH50
Complement testing evaluates proteins involved in immune system activity.
This test is included because complement patterns may provide immune-complex and lupus-related context. C3, C4, and CH50 can help support provider-guided review when lupus-like symptoms, immune-complex patterns, or urine abnormalities are present.
Rheumatoid Arthritis and Inflammatory Arthritis Context
Rheumatoid Factor
Rheumatoid factor is an antibody marker commonly reviewed in rheumatoid arthritis evaluations.
This test is included because rheumatoid factor may provide context for inflammatory joint pain, morning stiffness, joint swelling, and rheumatoid arthritis-related patterns. It is not diagnostic by itself and may be present in other conditions.
Cyclic Citrullinated Peptide, CCP Antibody IgG
CCP antibody is a rheumatoid arthritis-related marker.
This test is included because CCP IgG may add more specific rheumatoid arthritis context than rheumatoid factor alone. It is useful when joint pain, swelling, stiffness, or suspected inflammatory arthritis is being reviewed.
HLA-B27 Antigen
HLA-B27 is a genetic marker associated with certain inflammatory spine and joint conditions.
This test is included because HLA-B27 may provide context for inflammatory back pain, ankylosing spondylitis-related patterns, uveitis, psoriatic arthritis, and other spondyloarthritis-type concerns. It is not diagnostic by itself and should be interpreted with symptoms and imaging or clinical evaluation when appropriate.
Antiphospholipid Antibody Context
Beta-2-Glycoprotein I Antibodies, IgG, IgA, IgM
Beta-2-glycoprotein I antibodies are antiphospholipid antibody markers.
This test is included because these antibodies may provide context for antiphospholipid antibody patterns. They may be relevant when there is a history of clotting events, pregnancy loss, lupus-related concerns, livedo-type skin findings, or provider-directed autoimmune review.
Cardiolipin Antibody, IgG
Cardiolipin IgG is an antiphospholipid antibody marker.
This test is included because it adds antiphospholipid antibody context and may be reviewed with beta-2-glycoprotein antibodies and lupus anticoagulant evaluation.
Cardiolipin Antibody, IgM
Cardiolipin IgM is an antiphospholipid antibody marker.
This test is included because it adds another antiphospholipid antibody pattern for provider-guided interpretation.
Lupus Anticoagulant Evaluation with Reflex
Lupus anticoagulant evaluation is used as part of antiphospholipid antibody review.
This test is included because it may provide important clotting-related autoimmune context. Reflex testing means the lab may perform additional testing based on initial findings.
Reflex Test Notice: If reflex testing is performed, additional charges may apply.
Muscle Pain, Myositis and Recovery Context
Creatine Kinase, CK, Total
CK is an enzyme found mainly in muscle tissue.
This test is included because CK may provide context for muscle inflammation, muscle injury, statin-related muscle symptoms, exercise-related muscle stress, and myositis-related concerns.
Aldolase
Aldolase is an enzyme found in muscle and other tissues.
This test is included because aldolase may provide additional muscle inflammation context and can complement CK when myositis or muscle-related inflammatory patterns are being reviewed.
Lactate Dehydrogenase, LD
LD is an enzyme found in many tissues.
This test is included because LD may provide nonspecific tissue turnover, cellular stress, and recovery context. It is not specific, but it can add useful context when reviewed with CK, aldolase, symptoms, and other findings.
Coenzyme Q10
CoQ10 supports mitochondrial energy production and antioxidant function.
This test is included because CoQ10 may provide context for fatigue, muscle symptoms, statin-associated muscle complaints, mitochondrial energy, and recovery support.
Magnesium
Magnesium supports muscle function, nerve signaling, sleep, and energy production.
This test is included because magnesium may provide context for cramps, muscle tension, sleep disruption, pain sensitivity, fatigue, and neuromuscular wellness.
Celiac and Gut-Immune Context
Celiac Disease Comprehensive Panel
A celiac disease panel evaluates immune markers associated with celiac-related patterns.
This test is included because celiac-related immune activity may overlap with chronic pain, fatigue, anemia, nutrient deficiencies, gastrointestinal symptoms, joint pain, and autoimmune clustering.
Results should be interpreted with diet history, especially gluten intake, symptoms, and provider guidance.
Thyroid Function and Thyroid Autoimmunity
TSH
TSH is a key thyroid screening marker.
This test is included because thyroid dysfunction can overlap with fatigue, muscle aches, weakness, weight changes, mood changes, and chronic pain-like symptoms.
T4, Free
Free T4 measures the available form of thyroxine.
This test is included because it adds thyroid hormone production context beyond TSH alone.
Thyroid Peroxidase and Thyroglobulin Antibodies
These antibodies help evaluate autoimmune thyroid patterns.
This test is included because thyroid autoimmunity may overlap with other autoimmune conditions and may provide context when fatigue, hair changes, weight changes, mood symptoms, or thyroid-related concerns are present.
Kidney, Urine and Autoimmune Kidney Context
Cystatin C with eGFR
Cystatin C with eGFR provides kidney filtration context beyond creatinine alone.
This test is included because kidney function may be relevant in autoimmune disease, chronic inflammation, medication use, NSAID use, or chronic disease risk review.
Albumin, Random Urine with Creatinine
This urine test evaluates albumin relative to creatinine.
It is included because urine albumin may provide early kidney and vascular risk context. In autoimmune review, urine albumin can also provide kidney involvement context.
Protein, Total, Random Urine with Creatinine
This test evaluates total urine protein relative to creatinine.
It is included because broader urine protein findings may provide kidney involvement context beyond albumin alone, especially when autoimmune kidney patterns are a concern.
Urinalysis, UA, Complete
Urinalysis evaluates urine markers such as protein, blood, glucose, ketones, specific gravity, pH, and other findings.
This test is included because protein or blood in urine may provide important kidney and urinary context in autoimmune and inflammation evaluations.
Liver, Medication and Safety Context
Comprehensive Metabolic Panel, CMP
The CMP evaluates glucose, liver enzymes, kidney markers, electrolytes, calcium, albumin, total protein, and other metabolic markers.
This test is included because chronic pain and autoimmune review often benefits from liver, kidney, electrolyte, glucose, calcium, albumin, and protein context.
Gamma Glutamyl Transferase, GGT
GGT is a liver and bile duct enzyme.
This test is included because it adds liver and bile-flow context, especially when medications, supplements, alcohol use, metabolic liver concerns, or liver enzyme patterns are part of the review.
Bilirubin, Fractionated
Bilirubin, Fractionated measures total, direct, and indirect bilirubin.
This test is included because bilirubin patterns provide liver processing and bile-flow context beyond standard liver enzymes.
Iron, Nutrients, Methylation and Immune Support
Ferritin
Ferritin measures stored iron.
This test is included because ferritin may provide context for iron storage, fatigue, anemia, inflammation, and liver/metabolic patterns. Ferritin can rise with inflammation, so it should be interpreted with iron/TIBC, CBC, CRP, hs-CRP, and symptoms.
Iron and Total Iron Binding Capacity, TIBC
Iron and TIBC help evaluate circulating iron and iron transport capacity.
This test is included because iron availability may provide context for fatigue, anemia patterns, low stamina, inflammation, and ferritin interpretation.
QuestAssureD™ 25-Hydroxyvitamin D, D2, D3, LC/MS/MS
Vitamin D testing measures vitamin D status.
This test is included because vitamin D supports bone health, muscle function, immune health, inflammation balance, and fatigue-related wellness discussions.
Vitamin B12, Cobalamin
Vitamin B12 supports nerve function, red blood cell production, and energy metabolism.
This test is included because B12 status may provide context for fatigue, brain fog, numbness, tingling, neuropathy-like symptoms, and anemia-related patterns.
Methylmalonic Acid
Methylmalonic acid, or MMA, is a functional B12 marker.
This test is included because MMA can provide deeper B12 interpretation when serum B12 is borderline or symptoms suggest B12-related issues.
Vitamin B6, Pyridoxal Phosphate
Vitamin B6 supports neurotransmitter pathways, methylation, nerve function, immune function, and energy metabolism.
This test is included because B6 may provide context for nerve-related symptoms, fatigue, homocysteine interpretation, and methylation support.
Homocysteine
Homocysteine is influenced by vitamin B12, folate, vitamin B6, methylation pathways, kidney function, and vascular health.
This test is included because it provides methylation, B-vitamin, vascular, cognitive, and inflammatory context.
Selenium
Selenium supports thyroid-related pathways and antioxidant systems.
This test is included because selenium may provide thyroid and antioxidant context, especially since thyroid antibodies are included.
Zinc
Zinc supports immune function, wound healing, thyroid pathways, antioxidant function, and inflammatory balance.
This test is included because zinc may provide immune and recovery context in chronic inflammation and pain review.
OMEGACHECK™
OMEGACHECK™ evaluates omega fatty acid status.
This test is included because omega fatty acid patterns may provide context for inflammation balance, nutrition quality, cardiometabolic health, and recovery.
Metabolic Inflammation and Pain Overlap
Hemoglobin A1c
Hemoglobin A1c reflects average blood sugar over approximately the past two to three months.
This test is included because blood sugar patterns may provide context for metabolic inflammation, fatigue, neuropathy-like symptoms, and long-term metabolic wellness.
Insulin
Insulin helps move glucose from the bloodstream into cells.
This test is included because insulin resistance may overlap with inflammation, weight changes, fatigue, metabolic stress, and chronic pain patterns.
Uric Acid
Uric acid is a metabolic waste product.
This test is included because uric acid may provide context for gout risk, joint pain, kidney stone risk, blood pressure, kidney function, and metabolic inflammation.
Professional Reflex Testing Notice
This panel includes Lupus Anticoagulant Evaluation with Reflex. Reflex testing means the laboratory may automatically perform additional testing when initial findings meet specific criteria.
If reflex testing is performed, additional charges may apply. Reflex results should be reviewed with a licensed healthcare provider.
Related Biomarker Patterns This Panel May Help Identify
This panel may help identify or support provider-guided review of:
- CRP, hs-CRP, ESR, and fibrinogen inflammation patterns
- ANA and connective tissue disease-related antibody patterns
- Lupus-related antibody and complement patterns
- Rheumatoid factor and CCP antibody patterns
- Sjögren’s antibody patterns
- Antiphospholipid antibody patterns
- HLA-B27 inflammatory back pain context
- Celiac-related immune patterns
- CK, aldolase, and LD muscle patterns
- Thyroid function and thyroid antibody patterns
- Kidney filtration, urine albumin, urine protein, and urinalysis findings
- Ferritin, iron, and TIBC patterns
- Vitamin D, B12, MMA, B6, selenium, zinc, magnesium, and omega fatty acid status
- A1c, insulin, uric acid, and metabolic inflammation patterns
Professional Safety and Interpretation Notice
This panel is designed to support inflammation, autoimmune, and chronic pain biomarker review. It does not diagnose autoimmune disease, lupus, rheumatoid arthritis, Sjögren’s syndrome, antiphospholipid syndrome, celiac disease, thyroid disease, kidney disease, muscle disease, chronic pain syndromes, or any condition by itself.
Results should be interpreted with a licensed healthcare provider and reviewed alongside symptoms, physical exam findings, medications, supplements, personal medical history, family history, imaging when appropriate, and clinical context.
Do not stop or change medications or supplements without guidance from your healthcare provider.
How to Prepare for This Panel
Preparation may vary depending on the specific tests and lab instructions. In general:
- Bring a list of medications, supplements, vitamins, immune therapies, steroids, thyroid medications, NSAIDs, anticoagulants, and doses.
- Tell your provider if you take biotin, because it may interfere with some lab assays.
- Note symptoms such as joint pain, muscle pain, morning stiffness, swelling, rashes, dry eyes, dry mouth, fatigue, brain fog, numbness, tingling, digestive symptoms, or urine changes.
- Avoid unusually intense exercise before testing if CK, aldolase, or LD interpretation is important.
- Follow all collection instructions provided with your order.
What Happens After You Receive Your Results?
After results are available, biomarkers can be organized into key categories: inflammation, autoimmune screening, lupus-related markers, rheumatoid arthritis markers, antiphospholipid antibody context, Sjögren’s antibodies, celiac-related immune patterns, muscle inflammation, thyroid autoimmunity, kidney and urine involvement, liver safety, nutrient status, omega fatty acids, methylation, and metabolic inflammation.
During a provider review, you can discuss whether results suggest follow-up testing, repeat testing, rheumatology referral, gastroenterology review, kidney follow-up, medication review, nutrition changes, or additional clinical evaluation.
Additional Panels to Consider
Customers interested in the Inflammation, Autoimmune & Chronic Pain - Comprehensive Lab Panel may also consider:
- Inflammation, Autoimmune & Chronic Pain - Essential Lab Panel
- Inflammation, Autoimmune & Chronic Pain - Advanced Lab Panel
- Fatigue, Low Energy & Brain Fog Lab Panel
- Thyroid & Metabolism Lab Panel
- Vitamin, Mineral & Nutrient Deficiency Lab Panel
- Heavy Metals & Environmental Toxins Lab Panel
- Gut Health, Food Allergy & Nutrient Lab Panel
- Prediabetes & Insulin Resistance Lab Panel
- Medication & Supplement Safety Lab Panel
- Longevity & Healthy Aging Lab Panel
FAQ: Inflammation, Autoimmune & Chronic Pain - Comprehensive Lab Panel
What is the Inflammation, Autoimmune & Chronic Pain Comprehensive Lab Panel?
The Inflammation, Autoimmune & Chronic Pain Comprehensive Lab Panel is a broad blood and urine test panel that includes 46 tests and 158 biomarkers to evaluate inflammation, autoimmune patterns, lupus-related markers, rheumatoid arthritis markers, antiphospholipid antibodies, Sjögren’s antibodies, celiac-related immune markers, muscle pain markers, thyroid autoimmunity, kidney and urine findings, nutrients, omega status, and metabolic inflammation.
Does this panel diagnose autoimmune disease?
No. This panel does not diagnose autoimmune disease by itself. Results should be interpreted by a licensed healthcare provider using symptoms, exam findings, medical history, family history, and follow-up testing when appropriate.
What autoimmune markers are included?
This panel includes ANA, dsDNA, Sm and Sm/RNP antibodies, Sjögren’s SS-A/SS-B antibodies, complement C3/C4/CH50, rheumatoid factor, CCP antibody, antiphospholipid antibody markers, lupus anticoagulant evaluation, and HLA-B27.
Why are CRP, hs-CRP, and ESR included?
CRP, hs-CRP, and ESR provide inflammation context. They may help show that inflammation is present, but they do not identify the cause by themselves.
Why are CK, aldolase, and LD included?
CK, aldolase, and LD may provide muscle inflammation, muscle injury, tissue turnover, statin-associated muscle symptom, or recovery context.
Why are kidney and urine markers included?
Autoimmune and inflammatory patterns can sometimes involve the kidneys. Cystatin C, urine albumin/creatinine, urine protein/creatinine, and urinalysis help provide kidney and urine context.
Why is the celiac panel included?
Celiac-related immune activity may overlap with chronic pain, fatigue, anemia, nutrient deficiencies, digestive symptoms, joint pain, and autoimmune clustering.
Why are thyroid markers included?
Thyroid dysfunction and thyroid autoimmunity can overlap with fatigue, muscle pain, weakness, mood symptoms, weight changes, and autoimmune patterns.
Should I choose Essential, Advanced, or Comprehensive?
Choose Essential for a focused inflammation and joint-pain baseline, Advanced for deeper autoimmune and chronic pain context, and Comprehensive for the broadest autoimmune, lupus, rheumatoid, antiphospholipid, Sjögren’s, celiac, muscle, thyroid, kidney, nutrient, omega, and metabolic inflammation review.
Important Note
This panel is designed to help evaluate selected biomarkers related to inflammation, autoimmune patterns, chronic pain, joint pain, muscle pain, thyroid autoimmunity, kidney involvement, nutrient status, metabolic inflammation, and general wellness. It is not intended to diagnose, treat, cure, or prevent disease by itself. Results should be reviewed with a licensed healthcare provider.