Inflammation, Autoimmune & Chronic Pain - Advanced Lab Panel

The Inflammation, Autoimmune & Chronic Pain Advanced Lab Panel includes 41 tests and 138 biomarkers to support deeper review of inflammation, autoimmune screening, lupus-related markers, rheumatoid arthritis markers, Sjögren’s antibodies, celiac-related immune patterns, thyroid autoimmunity, chronic joint and muscle pain, kidney and urine health, nutrients, methylation, recovery, and metabolic inflammation markers.

Urine, Serum, Blood, Other, Random, Plasma-Unspecified Vial Pour
Phlebotomist
Autoimmune Advanced Panel, Inflammation Lab Panel, Chronic Pain Blood Test, Autoimmune Disease Screening Panel, Rheumatoid Arthritis Lab Panel, Lupus Blood Test Panel, Joint Pain Lab Panel, Chronic Inflammation Panel, Pain and Inflammation Panel

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Microalbumin Random Urine with Creatinine

Creatinine, Random Urine

Microalbumin

Microalbumin/Creatinine

Also known as: 6 bisphospate, Fructose-1

Aldolase

Aids in the diagnosis of primary disease of skeletal muscle myocardial infarction and viral hepatitis.

Legionella Antigen,

Also known as: ANA, ANA Screen IFA with Reflex to Titer and Pattern IFA, ANA with Reflux

ANA Screen, IFA

The antinuclear antibody (ANA) test is ordered to help screen for autoimmune disorders and is most often used as one of the tests to diagnose systemic lupus erythematosus (SLE).

Also known as: Bilirubin Fractionated

Bilirubin, Direct

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Bilirubin, Indirect

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Bilirubin, Total

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Also known as: C-Reactive Protein, CReactive Protein CRP, CRP

C-REACTIVE PROTEIN

C-reactive protein is produced by the liver. The level of CRP rises when there is inflammation throughout the body.

Also known as: CBC, CBC includes Differential and Platelets, CBC/PLT w/DIFF, Complete Blood Count (includes Differential and Platelets)

NOTE: Ulta Lab Tests provides CBC test results from Quest Diagnostics as they are reported. Often, different biomarker results are made available at different time intervals. When reporting the results, Ulta Lab Tests denotes those biomarkers not yet reported as 'pending' for every biomarker the test might report. Only biomarkers Quest Diagnostics observes are incorporated and represented in the final CBC test results provided by Ulta Lab Tests.

Absolute Band Neutrophils (Only Reported If Detected)

Immature forms of neutrophils are called neutrophilic band cells. Neutrophils are a type of white blood cell that is responsible for much of the body's protection against infection. Neutrophils are produced in the bone marrow and released into the bloodstream to travel to wherever they are needed. Large numbers of immature forms of neutrophils, called neutrophilic band cells, are produced by the bone marrow when the demand is high.

Absolute Basophils

Basophils normally constitute 1% or less of the total white blood cell count but may increase or decrease in certain diseases and are thought to be involved in allergic reactions.

Absolute Blasts (Only Reported If Detected)

Blasts are immature forms of white blood cells.

Absolute Eosinophils

Eosinophils (eos) respond to infections caused by parasites and play a role in allergic reactions (hypersensitivities)

Absolute Lymphocytes

Lymphocytes are white blood cells that exist in both the blood and the lymphatic system. They are divided into three types. The B lymphocytes (B cells) are antibody-producing cells that are essential for acquired, antigen-specific immune responses. The second type are T lymphocytes (T cells) some T cells help the body distinguish between "self" and "non-self" antigens while others initiate and control the extent of an immune response, boosting it as needed and then slowing it as the condition resolves. Other types of T cells directly attack and neutralize virus-infected or cancerous cells. The third type are natural killer cells (NK cells) that directly attack and kill abnormal cells such as cancer cells or those infected with a virus.

Absolute Metamyelocytes (Only Reported If Detected)

Metamyelocytes are immature forms of white blood cells.

Absolute Monocytes

Monocytes (mono), similar to neutrophils, move to an area of infection and engulf and destroy bacteria. They are associated more often with chronic rather than acute infections. They are also involved in tissue repair and other functions involving the immune system.

Absolute Myelocytes (Only Reported If Detected)

Myelocytes are immature forms of white blood cells.

Absolute Neutrophils

Neutrophils (neu) normally make up the largest number of circulating WBCs. They move into an area of damaged or infected tissue, where they engulf and destroy bacteria or sometimes fungi. Young neutrophils, recently released into circulation, are called bands.

Absolute Nucleated Rbc (Only Reported If Detected)

Nucleated Red Blood Cells (nRBC) ) the presence of NRBCs in the adult blood is usually associated with malignant neoplasms, bone marrow diseases, and other serious disorders.

Absolute Promyelocytes (Only Reported If Detected)

Promyelocytes are immature forms of white blood cells.

Band Neutrophils (Only Reported If Detected)

Immature forms of neutrophils are called neutrophilic band cells. Neutrophils are a type of white blood cell that is responsible for much of the body's protection against infection. Neutrophils are produced in the bone marrow and released into the bloodstream to travel to wherever they are needed. Large numbers of immature forms of neutrophils, called neutrophilic band cells, are produced by the bone marrow when the demand is high.

Basophils

Basophils normally constitute 1% or less of the total white blood cell count but may increase or decrease in certain diseases and are thought to be involved in allergic reactions.

Blasts (Only Reported If Detected)

Blasts are immature forms of white blood cells.

Eosinophils

Eosinophils are specialized white blood cells produced in the bone marrow and released into the bloodstream, where they normally make up only 0–6 % of circulating leukocytes. Their cytoplasm is packed with reddish‑orange granules that contain potent enzymes (e.g., major basic protein, eosinophil cationic protein) and inflammatory mediators. When the immune system detects large, multicellular invaders—such as helminth (worm) parasites—eosinophils migrate out of the blood and surround the pathogen, releasing these granule contents to damage the parasite’s outer surface and aid its destruction. Beyond parasite defense, eosinophils act as key orchestras of the allergic response. They accumulate in tissues exposed to allergens (airways in asthma, skin in eczema, GI tract in eosinophilic esophagitis) and secrete cytokines and lipid mediators that amplify inflammation, recruit additional immune cells, and contribute to symptoms like swelling, mucus production, and itching. Because of this pro‑inflammatory role, persistently elevated eosinophil counts—termed eosinophilia—can signal allergic disorders, drug hypersensitivity, or certain autoimmune and malignant conditions. Conversely, counts drop toward zero after glucocorticoid therapy or in acute stress states, reflecting the cells’ sensitivity to hormonal and immune regulation.

Hematocrit

Hematocrit is a blood test that measures the percentage of the volume of whole blood that is made up of red blood cells. This measurement depends on the number of red blood cells and the size of red blood cells.

Hemoglobin

Serum hemoglobin is a blood test that measures the level of free hemoglobin in the liquid part of the blood (the serum). Free hemoglobin is the hemoglobin outside of the red blood cells. Most of the hemoglobin is found inside the red blood cells, not in the serum.

Lymphocytes

Lymphocytes are white blood cells that exist in both the blood and the lymphatic system. They are divided into three types. The B lymphocytes (B cells) are antibody-producing cells that are essential for acquired, antigen-specific immune responses. The second type are T lymphocytes (T cells) some T cells help the body distinguish between "self" and "non-self" antigens while others initiate and control the extent of an immune response, boosting it as needed and then slowing it as the condition resolves. Other types of T cells directly attack and neutralize virus-infected or cancerous cells. The third type are natural killer cells (NK cells) that directly attack and kill abnormal cells such as cancer cells or those infected with a virus.

MCH

Mean corpuscular hemoglobin (MCH) is a calculation of the average amount of oxygen-carrying hemoglobin inside a red blood cell.

MCHC

Mean corpuscular hemoglobin concentration (MCHC) is a calculation of the average percentage of hemoglobin inside a red cell.

MCV

Mean corpuscular volume (MCV) is a measurement of the average size of RBCs.

Metamyelocytes (Only Reported If Detected)

Metamyelocytes are immature forms of white blood cells.

Monocytes

Monocytes (mono), similar to neutrophils, move to an area of infection and engulf and destroy bacteria. They are associated more often with chronic rather than acute infections. They are also involved in tissue repair and other functions involving the immune system.

MPV

Mean Platelet Volume (MPV) - When it indicates average size of platelets are small; older platelets are generally smaller than younger ones and a low MPV may mean that a condition is affecting the production of platelets by the bone marrow. When it indicates a high number of larger, younger platelets in the blood; this may be due to the bone marrow producing and releasing platelets rapidly into circulation.

Myelocytes (Only Reported If Detected)

Myelocytes are immature forms of white blood cells.

Neutrophils

Neutrophils are a type of white blood cell that is responsible for much of the body's protection against infection. Neutrophils are produced in the bone marrow and released into the bloodstream to travel to wherever they are needed.

Nucleated Rbc (Only Reported If Detected)

Nucleated Red Blood Cells (nRBC) ) the presence of NRBCs in the adult blood is usually associated with malignant neoplasms, bone marrow diseases, and other serious disorders.

Platelet Count

A platelet count is a test to measure how many platelets you have in your blood. Platelets help the blood clot. They are smaller than red or white blood cells.

Promyelocytes (Only Reported If Detected)

Promyelocytes are immature forms of white blood cells.

RDW

Red cell distribution width (RDW), which may be included in a CBC, is a calculation of the variation in the size of RBCs.

Reactive Lymphocytes (Only Reported If Detected)

Lymphocytes are white blood cells that exist in both the blood and the lymphatic system. They are divided into three types. The B lymphocytes (B cells) are antibody-producing cells that are essential for acquired, antigen-specific immune responses. The second type are T lymphocytes (T cells) some T cells help the body distinguish between "self" and "non-self" antigens while others initiate and control the extent of an immune response, boosting it as needed and then slowing it as the condition resolves. Other types of T cells directly attack and neutralize virus-infected or cancerous cells. The third type are natural killer cells (NK cells) that directly attack and kill abnormal cells such as cancer cells or those infected with a virus.

Red Blood Cell Count

An RBC count is a blood test that tells how many red blood cells (RBCs) you have. RBCs contain hemoglobin, which carries oxygen. How much oxygen your body tissues get depends on how many RBCs you have and how well they work.

White Blood Cell Count

A WBC count is a test to measure the number of white blood cells (WBCs) in the blood. WBCs help fight infections. They are also called leukocytes. There are five major types of white blood cells: basophils, eosinophils, lymphocytes (T cells and B cells), monocytes and neutrophils

Also known as: Celiac Panel

Immunoglobulin A

Interpretation

Tissue Transglutaminase

Tissue Transglutaminase

Also known as: CoQ10

Coenzyme Q10

Complement Component C3c

Complement Component C4c

Also known as: Chem 12, Chemistry Panel, Chemistry Screen, CMP, Complete Metabolic Panel, Comprehensive Metabolic Panel CMP, SMA 12, SMA 20

Albumin

Albumin is a protein made by the liver. A serum albumin test measures the amount of this protein in the clear liquid portion of the blood.

Albumin/Globulin Ratio

The ratio of albumin to globulin (A/G ratio) is calculated from measured albumin and calculated globulin (total protein - albumin). Normally, there is a little more albumin than globulins, giving a normal A/G ratio of slightly over 1. Because disease states affect the relative amounts of albumin and globulin, the A/G ratio may provide a clue as to the cause of the change in protein levels. A low A/G ratio may reflect overproduction of globulins, such as seen in multiple myeloma or autoimmune diseases, or underproduction of albumin, such as may occur with cirrhosis, or selective loss of albumin from the circulation, as may occur with kidney disease (nephrotic syndrome). A high A/G ratio suggests underproduction of immunoglobulins as may be seen in some genetic deficiencies and in some leukemias. More specific tests, such as liver enzyme tests and serum protein electrophoresis, must be performed to make an accurate diagnosis. With a low total protein that is due to plasma expansion (dilution of the blood), the A/G ratio will typically be normal because both albumin and globulin will be diluted to the same extent.

Alkaline Phosphatase

Alkaline phosphatase (ALP) is a protein found in all body tissues. Tissues with higher amounts of ALP include the liver, bile ducts, and bone.

Alt

Alanine transaminase (ALT) is an enzyme found in the highest amounts in the liver. Injury to the liver results in release of the substance into the blood.

AST

AST (aspartate aminotransferase) is an enzyme found in high amounts in liver, heart, and muscle cells. It is also found in lesser amounts in other tissues.

Bilirubin, Total

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Bun/Creatinine Ratio

A ratio between a person’s BUN and blood creatinine to help determine what is causing these concentrations to be higher than normal. The ratio of BUN to creatinine is usually between 10:1 and 20:1. An increased ratio may be due to a condition that causes a decrease in the flow of blood to the kidneys, such as congestive heart failure or dehydration. It may also be seen with increased protein, from gastrointestinal bleeding, or increased protein in the diet. The ratio may be decreased with liver disease (due to decrease in the formation of urea) and malnutrition.

Calcium

You have more calcium in your body than any other mineral. Calcium has many important jobs. The body stores more than 99 percent of its calcium in the bones and teeth to help make and keep them strong. The rest is throughout the body in blood, muscle and the fluid between cells. Your body needs calcium to help muscles and blood vessels contract and expand, to secrete hormones and enzymes and to send messages through the nervous system.

Carbon Dioxide

CO2 is carbon dioxide. Measures the amount of carbon dioxide in the liquid part of your blood, called the serum. In the body, most of the CO2 is in the form of a substance called bicarbonate (HCO3-). Therefore, the CO2 blood test is really a measure of your blood bicarbonate level.

Chloride

Chloride is a type of electrolyte. It works with other electrolytes such as potassium, sodium, and carbon dioxide (CO2). These substances help keep the proper balance of body fluids and maintain the body's acid-base balance. This is a measure of the amount of chloride in the fluid portion (serum) of the blood.

Creatinine

The creatinine blood test measures the level of creatinine in the blood. This test is done to see how well your kidneys work.

Egfr African American

Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

Egfr Non-Afr. American

Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

GFR-AFRICAN AMERICAN

GFR-NON AFRICAN AMERICAN

Globulin

Globulins is the collective term for most blood proteins other than albumin. Identifying the types of globulins can help diagnose certain disorders. Globulins are roughly divided into three groups: alpha, beta, and gamma globulins. Gamma globulines include various types of antibodies such as immunoglobulins (Ig) M, G, and A.

Glucose

A blood glucose test measures the amount of a sugar called glucose in a sample of your blood. Glucose is a major source of energy for most cells of the body, including those in the brain. The hormones insulin and glucagon help control blood glucose levels.

Potassium

Potassium is a mineral that the body needs to work normally. It helps nerves and muscles communicate. It also helps move nutrients into cells and waste products out of cells. A diet rich in potassium helps to offset some of sodium's harmful effects on blood pressure.

Protein, Total

The total protein is the total amount of two classes of proteins, albumin and globulin that are found in the fluid portion of your blood. Proteins are important parts of all cells and tissues. Your albumin helps prevent fluid from leaking out of blood vessels and your globulins are an important part of your immune system.

Sodium

Sodium is a substance that the body needs to work properly it is vital to normal body processes, including nerve and muscle function

Urea Nitrogen (Bun)

BUN stands for blood urea nitrogen. Urea nitrogen is what forms when protein breaks down. BUN measures the amount of urea nitrogen in the blood.

Also known as: CK (Total), CPK, CPK (Total), Creatine Kinase CK Total, Creatine Phosphokinase (CPK), Total CK

Creatine Kinase, Total

Also known as: ACPA, Anti-CCP, Anti-citrulline Antibody, Anti-cyclic Citrullinated Peptide, Anti-Cyclic Citrullinated Peptide (CCP) Antibody IgG, CCP, CCP Antibody, Citrullinated Peptide (CCP) IgG, Cyclic Citrullinated Peptide Antibody, Cyclic Citrullinated Peptide CCP Antibody IgG

Cyclic Citrullinated

CYSTATIN C

eGFR

Also known as: (dsDNA), Anti-DNA, DNA ds Antibody, Double-Stranded DNA Antibody, dsDNA, Native DNA

Dna (Ds) Antibody

Ferritin

Ferritin is a protein found inside cells that stores iron so your body can use it later. A ferritin test indirectly measures the amount of iron in your blood. The amount of ferritin in your blood (serum ferritin level) is directly related to the amount of iron stored in your body.

Also known as: Gamma Glutamyl Transferase GGT, Gamma-Glutamyl Transferase, Gamma-Glutamyl Transpeptidase, Gamma-GT, GGTP, GTP

Ggt

Gamma-glutamyl transpeptidase (GGT) is a test to measure the amount of the enzyme GGT in the blood.

Also known as: A1c, Glycated Hemoglobin, Glycohemoglobin, Glycosylated Hemoglobin, HA1c, HbA1c, Hemoglobin A1c, Hemoglobin A1c HgbA1C, Hgb A1c

HEMOGLOBIN A1C

The A1c test evaluates the average amount of glucose in the blood over the last 2 to 3 months. It does this by measuring the concentration of glycated (also often called glycosylated) hemoglobin A1c. Hemoglobin is an oxygen-transporting protein found inside red blood cells (RBCs). There are several types of normal hemoglobin, but the predominant form – about 95-98% – is hemoglobin A. As glucose circulates in the blood, some of it spontaneously binds to hemoglobin A. The hemoglobin molecules with attached glucose are called glycated hemoglobin. The higher the concentration of glucose in the blood, the more glycated hemoglobin is formed. Once the glucose binds to the hemoglobin, it remains there for the life of the red blood cell – normally about 120 days. The predominant form of glycated hemoglobin is referred to as HbA1c or A1c. A1c is produced on a daily basis and slowly cleared from the blood as older RBCs die and younger RBCs (with non-glycated hemoglobin) take their place. This test is used to monitor treatment in someone who has been diagnosed with diabetes. It helps to evaluate how well their glucose levels have been controlled by treatment over time. This test may be used to screen for and diagnose diabetes or risk of developing diabetes. In 2010, clinical practice guidelines from the American Diabetes Association (ADA) stated that A1c may be added to fasting plasma glucose (FPG) and oral glucose tolerance test (OGTT) as an option for diabetes screening and diagnosis. For monitoring purposes, an A1c of less than 7% indicates good glucose control and a lower risk of diabetic complications for the majority of diabetics. However, in 2012, the ADA and the European Association for the Study of Diabetes (EASD) issued a position statement recommending that the management of glucose control in type 2 diabetes be more "patient-centered." Data from recent studies have shown that low blood sugar (hypoglycemia) can cause complications and that people with risk of severe hypoglycemia, underlying health conditions, complications, and a limited life expectancy do not necessarily benefit from having a stringent goal of less than 7% for their A1c. The statement recommends that people work closely with their doctor to select a goal that reflects each person's individual health status and that balances risks and benefits.

Also known as: Homocysteine, Homocysteine Cardiovascular

HOMOCYSTEINE,

Also known as: C-Reactive Protein, Cardio CRP, Cardio hs-CRP, CRP, High Sensitivity CRP, High-sensitivity C-reactive Protein, High-sensitivity CRP, Highly Sensitive CRP, hsCRP, Ultra-sensitive CRP

Hs Crp

A high-sensitivity CRP (hs-CRP) test may be used by itself, in combination with other cardiac risk markers, or in combination with a lipoprotein-associated phospholipase A2 (Lp-PLA2) test that evaluates vascular inflammation. The hs-CRP test accurately detects low concentrations of C-reactive protein to help predict a healthy person's risk of cardiovascular disease (CVD). High-sensitivity CRP is promoted by some as a test for determining a person's risk level for CVD, heart attacks, and strokes. The current thinking is that hs-CRP can play a role in the evaluation process before a person develops one of these health problems.

Also known as: Insulin (fasting)

Insulin

Insulin is a hormone that is produced and stored in the beta cells of the pancreas. It is vital for the transportation and storage of glucose at the cellular level, helps regulate blood glucose levels, and has a role in lipid metabolism. When blood glucose levels rise after a meal, insulin is released to allow glucose to move into tissue cells, especially muscle and adipose (fat) cells, where is it is used for energy production. Insulin then prompts the liver to either store the remaining excess blood glucose as glycogen for short-term energy storage and/or to use it to produce fatty acids. The fatty acids are eventually used by adipose tissue to synthesize triglycerides to form the basis of a longer term, more concentrated form of energy storage. Without insulin, glucose cannot reach most of the body's cells. Without glucose, the cells starve and blood glucose levels rise to unhealthy levels. This can cause disturbances in normal metabolic processes that result in various disorders, including kidney disease, cardiovascular disease, and vision and neurological problems. Thus, diabetes, a disorder associated with decreased insulin effects, is eventually a life-threatening condition.

Also known as: Iron and TIBC, Iron and Total Iron Binding Capacity TIBC, TIBC

% Saturation

Iron Binding Capacity

Total iron binding capacity (TIBC) is a blood test to see if you may have too much or too little iron in the blood. Iron moves through the blood attached to a protein called transferrin. This test helps your doctor know how well that protein can carry iron in the blood.

Iron, Total

Iron is a mineral that our bodies need for many functions. For example, iron is part of hemoglobin, a protein which carries oxygen from our lungs throughout our bodies. It helps our muscles store and use oxygen. Iron is also part of many other proteins and enzymes. Your body needs the right amount of iron. If you have too little iron, you may develop iron deficiency anemia. Causes of low iron levels include blood loss, poor diet, or an inability to absorb enough iron from foods. People at higher risk of having too little iron are young children and women who are pregnant or have periods.

Also known as: Lactate Dehydrogenase LD, LDH

Ld

LDH isoenzymes is a test to check how much of the different types of lactate dehydrogenase (LDH) are in the blood. Measurement of LDH isoenzymes helps determine the location of any tissue damage. LDH is found in many body tissues such as the heart, liver, kidney, skeletal muscle, brain, blood cells, and lungs. LDH exists in 5 forms, which differ slightly in structure. LDH-1 is found primarily in heart muscle and red blood cells. LDH-2 is concentrated in white blood cells. LDH-3 is highest in the lung. LDH-4 is highest in the kidney, placenta, and pancreas. LDH-5 is highest in the liver and skeletal muscle.

Magnesium

Also known as: Magnesium RBC

Magnesium, Rbc

About half of the body's magnesium is found in bone. The other half is found inside cells of body tissues and organs. Magnesium is needed for nearly all chemical processes in the body. It helps maintain normal muscle and nerve function, and keeps the bones strong. Magnesium is also needed for the heart to function normally and to help regulate blood pressure. Magnesium also helps the body control blood sugar level and helps support the body's defense (immune) system.

Methylmalonic Acid

Also known as: Protein Total Random Urine with Creatini

Creatinine, Random Urine

Protein, Total, Random Ur

Protein/Creatinine Ratio

Vitamin D, 25-Oh, D2

Vitamin D2 ((ergocalciferol,) is found in fortified foods and in most vitamin preparations and supplements. Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. The D2 form is found in fortified foods and in most vitamin preparations and supplements. Vitamin D2 is effective when it is converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Vitamin D, 25-Oh, D3

Vitamin D3 (cholecalcifero) which comes from animals. Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. Vitamin D3 is the form produced in the body and is also used in some supplements. Vitamin D3 are is converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Vitamin D, 25-Oh, Total

Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. The chemical structures of the types of vitamin D are slightly different, and they are named vitamin D2 (ergocalciferol, which comes from plants) and vitamin D3 (cholecalciferol, which comes from animals). The D2 form is found in fortified foods and in most vitamin preparations and supplements. Vitamin D3 is the form produced in the body and is also used in some supplements. Vitamin D2 and D3 are equally effective when they are converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Also known as: RF

Rheumatoid Factor

Rheumatoid factor (RF) is a blood test that measures the amount of the RF antibody in the blood. An abnormal result means the test is positive, which means higher levels of rheumatoid factor have been detected in your blood. Most patients with rheumatoid arthritis or Sjogren syndrome have positive RF tests. The higher the level, the more likely one of these conditions is present. Not everyone with higher levels of rheumatoid factor has rheumatoid arthritis or Sjogren syndrome.

Also known as: ESR, SED RATE, Sed Rate by Modified Westergren ESR

Sed Rate By Modified

Erythrocyte sedimentation rate (ESR) is an indirect measure of the degree of inflammation present in the body. It actually measures the rate of fall (sedimentation) of erythrocytes (red blood cells) in a sample of blood.

Selenium

Also known as: Sjgrens Antibodies SSA SSB, SS-A & SS-B

Sjogren's Antibody (Ss-A)

Sjogren's Antibody (Ss-B)

Also known as: Sm and SmRNP Antibodies

Sm Antibody

Sm/Rnp Antibody

Also known as: Free T3, FT3, T3 Free

T3, Free

This test measures the amount of triiodothyronine, or T3, in the blood.

Also known as: Free T4, FT4, T4 Free

T4, Free

The free T4 test is not affected by protein levels. Since free T4 is the active form of thyroxine, the free T4 test is may be a more accurate reflection of thyroid hormone function.

Thyroglobulin Antibodies

Measurement of thyroglobulin antibodies is useful in the diagnosis and management of a variety of thyroid disorders including Hashimoto's thyroiditis, Graves Disease and certain types of goiter.

Thyroid Peroxidase

Also known as: Thyroid Stimulating Hormone Test, Thyrotropin Test

TSH

A TSH test is a lab test that measures the amount of thyroid stimulating hormone (TSH) in your blood. TSH is produced by the pituitary gland. It tells the thyroid gland to make and release thyroid hormones into the blood.

Also known as: Serum Urate, UA

Uric Acid

Uric acid is a chemical created when the body breaks down substances called purines. Purines are found in some foods and drinks. These include liver, anchovies, mackerel, dried beans and peas, and beer. Most uric acid dissolves in blood and travels to the kidneys. From there, it passes out in urine. If your body produces too much uric acid or doesn't remove enough if it, you can get sick. A high level of uric acid in the blood is called hyperuricemia.

Also known as: UA, Complete, Urinalysis UA Complete, Urine Analysis, Complete

Amorphous Sediment (Only Reported If Detected)

Appearance

Bacteria

Bacteria are living things that have only one cell. Most bacteria won't hurt you - less than 1 percent of the different types make people sick. Many are helpful. Some bacteria help to digest food, destroy disease-causing cells, and give the body needed vitamins. But infectious bacteria can make you ill. They reproduce quickly in your body. Many give off chemicals called toxins, which can damage tissue and make you sick. Examples of bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli.

Bilirubin

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Calcium Oxalate Crystals (Only Reported If Detected)

Calcium oxalate is a chemical compound that forms envelope-shaped crystals. A major constituent of human kidney stones.

Casts (Only Reported If Detected)

Urinary casts are cylindrical structures produced by the kidney and present in the urine in certain disease states. They form in the distal convoluted tubule and collecting ducts of nephrons, then dislodge and pass into the urine, where they can be detected by microscopy.

Color

Crystals (Only Reported If Detected)

Abnormal crystals may appear in urine as a result of pathology or due to normal catabolism

Glucose

A blood glucose test measures the amount of a sugar called glucose in a sample of your blood. Glucose is a major source of energy for most cells of the body, including those in the brain. The hormones insulin and glucagon help control blood glucose levels.

Granular Cast (Only Reported If Detected)

The second-most common type of cast, granular casts can result either from the breakdown of cellular casts or the inclusion of aggregates of plasma proteins (e.g., albumin) or immunoglobulin light chains. Depending on the size of inclusions, they can be classified as fine or coarse, though the distinction has no diagnostic significance. Their appearance is generally more cigar-shaped and of a higher refractive index than hyaline casts. While most often indicative of chronic renal disease, these casts, as with hyaline casts, can also be seen for a short time following strenuous exercise

Hyaline Cast

Urinary casts are tiny tube-shaped particles. Urinary casts may be made up of white blood cells, red blood cells, kidney cells, or substances such as protein or fat. The most common type of cast, hyaline casts are solidified Tamm-Horsfall mucoprotein secreted from the tubular epithelial cells of individual nephrons. Low urine flow, concentrated urine, or an acidic environment can contribute to the formation of hyaline casts, and, as such, they may be seen in normal individuals in dehydration or vigorous exercise. Hyaline casts are cylindrical and clear, with a low refractive index,

Ketones

Ketones are substances produced in the liver when fat cells break down in the blood. A serum ketone test is a measurement of how many ketones are in the blood.

Leukocyte Esterase

Leukocyte esterase is a urine test to look for white blood cells and other signs associated with infection.

Nitrite

Occult Blood

The test looks for hidden (occult) blood in a specimen sample. It can find blood even if you cannot see it yourself.

Ph

Level of acid

Protein

Body fluids contain many different proteins that serve diverse functions such as transport of nutrients, removal of toxins, control of metabolic processes, and defense against invaders. Protein electrophoresis is a method for separating these proteins based on their size and electrical charge. When body fluids are separated by electrophoresis, they form a characteristic pattern of bands of different widths and intensities, reflecting the mixture of proteins present. This pattern is divided into five fractions, called albumin, alpha 1, alpha 2, beta, and gamma. In some cases, the beta fraction is further divided into beta 1 and beta 2. Albumin, which is produced in the liver, accounts for about 60% of the protein in the blood. "Globulins" is a collective term used to refer to proteins other than albumin. With the exception of the immunoglobulins and some complement proteins, most of the globulins are also produced in the liver. Immunofixation electrophoresis (IFE) is a method used to identify abnormal bands seen on serum, urine, or CSF protein electrophoresis, as to which type of antibody (immunoglobulin) is present.

Rbc

RBCs contain hemoglobin, which carries oxygen. How much oxygen your body tissues get depends on how many RBCs you have and how well they work.

Reducing Substances (Only Reported If Detected)

Renal Epithelial Cells (Only Reported If Detected)

Specific Gravity

Squamous Epithelial Cells

Transitional Epithelial (Only Reported If Detected)

Triple Phosphate Crystals (Only Reported If Detected)

Struvite stones (triple phosphate/magnesium ammonium phosphate) - about 10–15% of urinary calculi are composed of struvite (ammonium magnesium phosphate, NH4MgPO4·6H2O).[44] Struvite stones (also known as "infection stones", urease or triple-phosphate stones), form most often in the presence of infection by urea-splitting bacteria

Uric Acid Crystals (Only Reported If Detected)

Abnormal crystals may appear in urine as a result of pathology or due to normal catabolism

WBC

WBCs help fight infections. They are also called leukocytes. There are five major types of white blood cells: basophils, eosinophils, lymphocytes (T cells and B cells), monocytes and neutrophils

YEAST (Only Reported If Detected)

Candida is the scientific name for yeast. It is a fungus that lives almost everywhere, including in your body. Usually, your immune system keeps yeast under control. If you are sick or taking antibiotics, it can multiply and cause an infection.

Also known as: Cobalamin, Folic Acid, Vitamin B 12, Vitamin B 12 and Folic Acid, Vitamin B12 Cobalamin and Folate Panel Serum, Vitamin B12/Folic Acid

Folate, Serum

Folate is part of the B complex of vitamins and is measures the levels of folate in the liquid portion of the blood, the serum or plasma, to detect deficiencies. Folate is necessary for normal RBC formation, tissue and cellular repair, and DNA synthesis.. A deficiency inr folate can lead to macrocytic anemia. Megaloblastic anemia, a type of macrocytic anemia, is characterized by the production of fewer but larger RBCs called macrocytes, in addition to some cellular changes in the bone marrow.

Vitamin B12

Vitamin B12 is part of the B complex of vitamins and measurea the levels of vitamin B12 in the liquid portion of the blood, the serum or plasma, to detect deficiencies. Cobalamine, or vitamin B12, is found in animal products such as red meat, fish, poultry, milk, yogurt, and eggs and is not produced in the human body. In recent years, fortified cereals, breads, and other grain products have also become important dietary sources of B12. Vitamin B12 is necessary for normal RBC formation, tissue and cellular repair, and DNA synthesis. B12 is important for nerve health. A deficiency in B12 can lead to macrocytic anemia. Megaloblastic anemia, a type of macrocytic anemia, is characterized by the production of fewer but larger RBCs called macrocytes, in addition to some cellular changes in the bone marrow. B12 deficiency can lead to varying degrees of neuropathy, nerve damage that can cause tingling and numbness in the affected person's hands and feet.

Also known as: B6, B6 Vitamin, Pyridoxal, Pyridoxal Phosphate, Pyridoxal Phosphate (PLP), Vitamin B6 Pyridoxal Phosphate

Vitamin B6

Also known as: ZN, Plasma

Zinc

*Important Information on Lab Test Processing Times: Ulta Lab Tests is committed to informing you about the processing times for your lab tests processed through a national lab. Please note that the estimated processing time for each test, indicated in business days, is based on data from the past 30 days across the 13 laboratories for each test. These estimates are intended to serve as a guide and are not guarantees. Factors such as laboratory workload, weather conditions, holidays, and the need for additional testing or maintenance can influence actual processing times. We aim to offer estimates to help you plan accordingly. Please understand that these times may vary, and processing times are not guaranteed. Thank you for choosing Ulta Lab Tests for your laboratory needs.

The Inflammation, Autoimmune & Chronic Pain - Advanced Lab Panel panel contains 41 tests with 139 biomarkers .

Overview

The Inflammation, Autoimmune & Chronic Pain - Advanced Lab Panel is designed for people who want a deeper lab-based review of biomarkers related to inflammation, autoimmune screening, chronic pain, joint pain, muscle pain, fatigue, thyroid autoimmunity, celiac-related immune patterns, kidney and urine involvement, nutrient status, methylation, recovery, and metabolic inflammation.

This panel includes 41 tests and 138 biomarkers to support provider-guided conversations about systemic inflammation, lupus-related markers, rheumatoid arthritis markers, Sjögren’s antibodies, celiac-related immune markers, muscle inflammation, thyroid autoimmunity, kidney risk, liver safety, iron status, B-vitamin status, vitamin D, magnesium, selenium, zinc, CoQ10, and metabolic inflammation.

This panel does not diagnose autoimmune disease, lupus, rheumatoid arthritis, Sjögren’s syndrome, celiac disease, thyroid disease, kidney disease, chronic pain syndromes, or muscle disease by itself. Results should be reviewed with a licensed healthcare provider and interpreted with symptoms, physical exam findings, medications, supplements, personal history, family history, and clinical context.


Why Order This Panel?

The Inflammation, Autoimmune & Chronic Pain - Advanced Lab Panel may be helpful for people who want more than a basic inflammation panel and want deeper insight into autoimmune, joint, muscle, thyroid, gut-immune, kidney, nutrient, and metabolic patterns.

This panel may help provide insight into:

  • General inflammation with CRP, hs-CRP, and ESR
  • Autoimmune screening with ANA by IFA and reflex titer/pattern
  • Lupus-related markers, including dsDNA, Sm, Sm/RNP, and complement C3/C4
  • Rheumatoid arthritis-related markers, including rheumatoid factor and CCP antibody
  • Sjögren’s antibodies
  • Celiac-related immune markers
  • Muscle inflammation or muscle injury markers
  • Thyroid function and thyroid autoimmunity
  • Kidney filtration, urine albumin, urine protein, and urinalysis findings
  • Liver and bile-flow markers
  • Iron storage and iron availability
  • Vitamin D, B12, folate, B6, magnesium, RBC magnesium, zinc, selenium, CoQ10, and methylmalonic acid
  • Blood sugar, insulin, uric acid, and metabolic inflammation patterns

This Panel May Be Helpful For People With

  • Chronic inflammation concerns
  • Joint pain or stiffness
  • Morning stiffness
  • Muscle aches, cramps, or weakness
  • Chronic pain with unclear cause
  • Fatigue or low energy
  • Brain fog or poor focus
  • Swelling, redness, or tenderness in joints
  • Dry eyes or dry mouth
  • Rashes or photosensitivity
  • Numbness, tingling, or neuropathy-like symptoms
  • Digestive symptoms with possible celiac or gluten-related concerns
  • Thyroid symptoms or known thyroid antibodies
  • Family history of autoimmune disease
  • History of abnormal ANA, RF, CCP, CRP, ESR, or thyroid antibodies
  • Kidney or urine findings that need follow-up
  • Interest in a deeper autoimmune and inflammation baseline

What This Panel Helps Evaluate

This panel helps evaluate selected biomarkers related to:

  • General inflammation
  • Autoimmune screening
  • Lupus-related markers
  • Rheumatoid arthritis-related markers
  • Sjögren’s antibody patterns
  • Celiac-related immune patterns
  • Muscle inflammation and muscle injury context
  • Thyroid function and thyroid autoimmunity
  • Kidney and urine involvement
  • Liver and bile-flow context
  • Iron status and blood health
  • Nutrient and methylation status
  • Metabolic inflammation
  • Chronic pain and recovery context

Which Tier Is Right for Me?

Essential Lab Panel

The Inflammation, Autoimmune & Chronic Pain - Essential Lab Panel is best for people who want a focused first-step inflammation and chronic pain baseline. It typically reviews ANA screening, CRP, hs-CRP, ESR, RF, CCP, CBC, CMP, ferritin, iron/TIBC, thyroid autoimmunity, TSH, vitamin D, B12, magnesium, uric acid, and urinalysis.

Choose Essential if you want an accessible starting point for inflammation, joint pain, thyroid overlap, iron status, nutrient status, uric acid, and general wellness.

Advanced Lab Panel

The Inflammation, Autoimmune & Chronic Pain - Advanced Lab Panel is best for people who want deeper autoimmune and chronic pain context. It includes 41 tests and 138 biomarkers and adds connective tissue disease markers, lupus-related markers, complements, Sjögren’s antibodies, celiac testing, muscle enzymes, kidney protein markers, liver/bile markers, methylation markers, metabolic inflammation markers, and recovery markers.

Choose Advanced if symptoms are persistent or if you want a broader review of autoimmune patterns, muscle pain, gut-immune markers, kidney/urine involvement, methylation, metabolic inflammation, and recovery.

Comprehensive Lab Panel

The Inflammation, Autoimmune & Chronic Pain - Comprehensive Lab Panel is the broadest option. It may include premium markers for antiphospholipid antibody context, lupus anticoagulant evaluation, HLA-B27, fibrinogen, omega fatty acid status, Sjögren’s antibodies, celiac-related immune markers, muscle inflammation, kidney involvement, and broad autoimmune/chronic pain review.

Choose Comprehensive if you want the widest review of systemic inflammation, autoimmune screening, lupus-related markers, rheumatoid arthritis markers, antiphospholipid antibodies, Sjögren’s, celiac-related inflammation, HLA-B27 inflammatory back pain context, thyroid autoimmunity, kidney/urine involvement, muscle pain, nutrient deficiencies, omega status, and metabolic inflammation.


Tests Included and Why They Matter

Core Inflammation Markers

C-Reactive Protein, CRP

CRP is a blood marker that can rise when inflammation is present.

This test is included because it provides broad inflammation context. CRP may be reviewed when symptoms include joint pain, swelling, infection-like symptoms, inflammatory flares, autoimmune concerns, unexplained pain, or chronic pain patterns. CRP does not identify the cause of inflammation by itself, so it should be interpreted with ESR, hs-CRP, CBC, symptoms, history, and provider guidance.

hs-CRP

High-sensitivity C-reactive protein is a more sensitive form of CRP often used for low-grade inflammation and cardiometabolic inflammation context.

This test is included because chronic low-grade inflammation may overlap with pain, metabolic risk, cardiovascular wellness, fatigue, and systemic inflammatory patterns. It is useful alongside standard CRP because each may support a different clinical question.

Sed Rate by Modified Westergren, ESR

ESR is a broad inflammation marker.

This test is included because ESR can provide additional inflammation context, especially when autoimmune or chronic inflammatory patterns are being reviewed. ESR may change more slowly than CRP and should be interpreted with symptoms, CRP, hs-CRP, CBC, and other findings.


Autoimmune Screening and Connective Tissue Disease Context

ANA Screen, IFA with Reflex to Titer and Pattern, IFA

ANA testing evaluates antinuclear antibody patterns using an immunofluorescence assay, or IFA. If the ANA screen meets reflex criteria, the laboratory may report titer and pattern information.

This test is included because ANA may provide systemic autoimmune screening context when symptoms suggest immune-mediated disease, such as unexplained joint pain, rashes, photosensitivity, mouth ulcers, dry eyes, dry mouth, fatigue, or other systemic symptoms.

ANA results should not be interpreted alone. Positive ANA findings can occur in people without autoimmune disease, so results should be reviewed with symptoms, exam findings, family history, and provider guidance.

Reflex Test Notice: If reflex titer and pattern testing is performed, additional charges may apply.

DNA, ds Antibody

Double-stranded DNA antibodies are often reviewed in lupus-related evaluations.

This test is included because dsDNA may provide lupus-related antibody context when symptoms, ANA findings, complement patterns, or urine findings suggest provider-guided autoimmune follow-up.

Sm and Sm/RNP Antibodies

Sm and Sm/RNP antibodies are connective tissue disease-related markers.

These tests are included because they may provide context for lupus-related and mixed connective tissue disease-related patterns. They should be interpreted with ANA, dsDNA, complements, symptoms, and provider guidance.

Sjögren’s Antibodies, SS-A and SS-B

SS-A and SS-B antibodies are commonly reviewed in Sjögren’s-related evaluations.

These tests are included because Sjögren’s-related patterns may overlap with dry eyes, dry mouth, fatigue, joint pain, neuropathy-like symptoms, and other systemic symptoms.

Complement Component C3c and C4c

Complement testing evaluates proteins involved in immune system activity.

This test is included because complement patterns may provide immune-complex and lupus-related context. C3 and C4 can help support provider-guided review when lupus-like symptoms, immune-complex patterns, or urine abnormalities are present.


Rheumatoid Arthritis and Joint Pain Support Markers

Rheumatoid Factor

Rheumatoid factor is an antibody marker commonly reviewed in rheumatoid arthritis evaluations.

This test is included because rheumatoid factor may provide context for inflammatory joint pain, morning stiffness, joint swelling, and rheumatoid arthritis-related patterns. It is not diagnostic by itself and may be present in other conditions or sometimes in people without rheumatoid arthritis.

Cyclic Citrullinated Peptide, CCP Antibody IgG

CCP antibody is a rheumatoid arthritis-related marker.

This test is included because CCP IgG may add more specific rheumatoid arthritis context than rheumatoid factor alone. It is useful when joint pain, swelling, stiffness, or suspected inflammatory arthritis is being reviewed. CCP should be interpreted with RF, CRP, ESR, symptoms, exam findings, and provider guidance.


Muscle Pain, Myositis and Recovery Context

Creatine Kinase, CK, Total

CK is an enzyme found mainly in muscle tissue.

This test is included because CK may provide context for muscle inflammation, muscle injury, statin-related muscle symptoms, exercise-related muscle stress, and myositis-related concerns.

Aldolase

Aldolase is an enzyme found in muscle and other tissues.

This test is included because aldolase may provide additional muscle inflammation context and can complement CK when myositis or muscle-related inflammatory patterns are being reviewed.

Lactate Dehydrogenase, LD

LD is an enzyme found in many tissues.

This test is included because LD may provide nonspecific tissue turnover, cellular stress, and recovery context. It is not specific, but it can add useful context when reviewed with CK, aldolase, symptoms, and other findings.

Coenzyme Q10

CoQ10 supports mitochondrial energy production and antioxidant function.

This test is included because CoQ10 may provide context for fatigue, muscle symptoms, statin-associated muscle complaints, mitochondrial energy, and recovery support.

Magnesium

Magnesium supports muscle function, nerve signaling, sleep, and energy production.

This test is included because magnesium may provide context for cramps, muscle tension, sleep disruption, pain sensitivity, fatigue, and neuromuscular wellness.

Magnesium, RBC

RBC magnesium may provide additional magnesium status context.

This test is included because deeper magnesium evaluation may be useful when chronic pain, cramps, fatigue, stress symptoms, or muscle symptoms are present.


Celiac and Gut-Immune Context

Celiac Disease Comprehensive Panel

A celiac disease panel evaluates immune markers associated with celiac-related patterns.

This test is included because celiac-related immune activity may overlap with chronic pain, fatigue, anemia, nutrient deficiencies, gastrointestinal symptoms, joint pain, and autoimmune clustering.

Results should be interpreted with diet history, especially gluten intake, symptoms, and provider guidance.


Thyroid Function and Thyroid Autoimmunity

TSH

TSH is a key thyroid screening marker.

This test is included because thyroid dysfunction can overlap with fatigue, muscle aches, weakness, weight changes, mood symptoms, brain fog, and chronic pain-like symptoms.

T4, Free

Free T4 measures the available form of thyroxine.

This test is included because it adds thyroid hormone production context beyond TSH alone.

T3, Free

Free T3 measures active thyroid hormone availability.

This test is included because thyroid hormone activity may overlap with fatigue, muscle symptoms, temperature sensitivity, metabolism, and energy patterns.

Thyroid Peroxidase and Thyroglobulin Antibodies

These antibodies help evaluate autoimmune thyroid patterns.

This test is included because thyroid autoimmunity may overlap with other autoimmune conditions and may provide context when fatigue, hair changes, weight changes, mood symptoms, or thyroid-related concerns are present.


Kidney, Urine and Autoimmune Kidney Context

Cystatin C with eGFR

Cystatin C with eGFR provides kidney filtration context beyond creatinine alone.

This test is included because kidney function may be relevant in autoimmune disease, chronic inflammation, medication use, NSAID use, or chronic disease risk review.

Albumin, Random Urine with Creatinine

This urine test evaluates albumin relative to creatinine.

It is included because urine albumin may provide early kidney and vascular risk context. In autoimmune review, urine albumin can also provide kidney involvement context.

Protein, Total, Random Urine with Creatinine

This test evaluates total urine protein relative to creatinine.

It is included because broader urine protein findings may provide kidney involvement context beyond albumin alone, especially when autoimmune kidney patterns are a concern.

Urinalysis, UA, Complete

Urinalysis evaluates urine markers such as protein, blood, glucose, ketones, specific gravity, pH, and other findings.

This test is included because protein or blood in urine may provide important kidney and urinary context in autoimmune and inflammation evaluations.


Liver, Medication and Safety Context

Comprehensive Metabolic Panel, CMP

The CMP evaluates glucose, liver enzymes, kidney markers, electrolytes, calcium, albumin, total protein, and other metabolic markers.

This test is included because chronic pain and autoimmune review often benefit from liver, kidney, electrolyte, glucose, calcium, albumin, and protein context.

Gamma Glutamyl Transferase, GGT

GGT is a liver and bile duct enzyme.

This test is included because it adds liver and bile-flow context, especially when medications, supplements, alcohol use, metabolic liver concerns, or liver enzyme patterns are part of the review.

Bilirubin, Fractionated

Bilirubin, Fractionated measures total, direct, and indirect bilirubin.

This test is included because bilirubin patterns provide liver processing and bile-flow context beyond standard liver enzymes.


Iron, Nutrients, Methylation and Immune Support

Ferritin

Ferritin measures stored iron.

This test is included because ferritin may provide context for iron storage, fatigue, anemia, inflammation, and liver/metabolic patterns. Ferritin can rise with inflammation, so it should be interpreted with iron/TIBC, CBC, CRP, hs-CRP, and symptoms.

Iron and Total Iron Binding Capacity, TIBC

Iron and TIBC help evaluate circulating iron and iron transport capacity.

This test is included because iron availability may provide context for fatigue, anemia patterns, low stamina, inflammation, and ferritin interpretation.

QuestAssureD™ 25-Hydroxyvitamin D, D2, D3, LC/MS/MS

Vitamin D testing measures vitamin D status.

This test is included because vitamin D supports bone health, muscle function, immune health, inflammation balance, and fatigue-related wellness discussions.

Vitamin B12 and Folate Panel, Serum

This panel measures vitamin B12 and folate.

Vitamin B12 and folate support nerve function, red blood cell production, DNA synthesis, methylation, and energy metabolism. This test is included because B12 and folate status may provide context for fatigue, brain fog, numbness, tingling, neuropathy-like symptoms, anemia-related patterns, and homocysteine interpretation.

Methylmalonic Acid

Methylmalonic acid, or MMA, is a functional B12 marker.

This test is included because MMA can provide deeper B12 interpretation when serum B12 is borderline or symptoms suggest B12-related issues.

Vitamin B6, Pyridoxal Phosphate

Vitamin B6 supports neurotransmitter pathways, methylation, nerve function, immune function, and energy metabolism.

This test is included because B6 may provide context for nerve-related symptoms, fatigue, homocysteine interpretation, and methylation support.

Homocysteine

Homocysteine is influenced by vitamin B12, folate, vitamin B6, methylation pathways, kidney function, and vascular health.

This test is included because it provides methylation, B-vitamin, vascular, cognitive, and inflammatory context.

Selenium

Selenium supports thyroid-related pathways and antioxidant systems.

This test is included because selenium may provide thyroid and antioxidant context, especially since thyroid antibodies are included.

Zinc

Zinc supports immune function, wound healing, thyroid pathways, antioxidant function, and inflammatory balance.

This test is included because zinc may provide immune and recovery context in chronic inflammation and pain review.


Metabolic Inflammation and Pain Overlap

Hemoglobin A1c

Hemoglobin A1c reflects average blood sugar over approximately the past two to three months.

This test is included because blood sugar patterns may provide context for metabolic inflammation, fatigue, neuropathy-like symptoms, and long-term metabolic wellness.

Insulin

Insulin helps move glucose from the bloodstream into cells.

This test is included because insulin resistance may overlap with inflammation, weight changes, fatigue, metabolic stress, and chronic pain patterns.

Uric Acid

Uric acid is a metabolic waste product.

This test is included because uric acid may provide context for gout risk, joint pain, kidney stone risk, blood pressure, kidney function, and metabolic inflammation.


Professional Reflex Testing Notice

This panel includes ANA Screen, IFA with Reflex to Titer and Pattern, IFA. Reflex testing means the laboratory may automatically perform additional testing when initial findings meet specific criteria.

If reflex testing is performed, additional charges may apply. Reflex results should be reviewed with a licensed healthcare provider.


Related Biomarker Patterns This Panel May Help Identify

This panel may help identify or support provider-guided review of:

  • CRP, hs-CRP, and ESR inflammation patterns
  • ANA screening and reflex titer/pattern findings
  • Lupus-related dsDNA and Sm/SmRNP patterns
  • Sjögren’s antibody patterns
  • Complement C3/C4 immune activity patterns
  • Rheumatoid factor and CCP antibody patterns
  • Celiac-related immune patterns
  • CK, aldolase, and LD muscle patterns
  • Thyroid function and thyroid antibody patterns
  • Kidney filtration, urine albumin, urine protein, and urinalysis findings
  • GGT and bilirubin liver/bile-flow patterns
  • Ferritin, iron, and TIBC patterns
  • Vitamin D, B12, folate, MMA, B6, selenium, zinc, magnesium, and RBC magnesium status
  • A1c, insulin, uric acid, and metabolic inflammation patterns

Professional Safety and Interpretation Notice

This panel is designed to support inflammation, autoimmune, and chronic pain biomarker review. It does not diagnose autoimmune disease, lupus, rheumatoid arthritis, Sjögren’s syndrome, celiac disease, thyroid disease, kidney disease, muscle disease, chronic pain syndromes, nutrient deficiency, or metabolic disease by itself.

Results should be interpreted with a licensed healthcare provider and reviewed alongside symptoms, physical exam findings, medications, supplements, personal medical history, family history, imaging when appropriate, and clinical context.

Do not stop or change medications or supplements without guidance from your healthcare provider.


How to Prepare for This Panel

Preparation may vary depending on the specific tests and lab instructions. In general:

  • Bring a list of medications, supplements, vitamins, immune therapies, steroids, thyroid medications, NSAIDs, anticoagulants, and doses.
  • Tell your provider if you take biotin, because it may interfere with some lab assays.
  • Note symptoms such as joint pain, muscle pain, morning stiffness, swelling, rashes, dry eyes, dry mouth, fatigue, brain fog, numbness, tingling, digestive symptoms, or urine changes.
  • Avoid unusually intense exercise before testing if CK, aldolase, or LD interpretation is important.
  • Drink water normally unless instructed otherwise.
  • Follow all collection instructions provided with your order.

What Happens After You Receive Your Results?

After results are available, biomarkers can be organized into key categories: inflammation, autoimmune screening, lupus-related markers, rheumatoid arthritis markers, Sjögren’s antibodies, celiac-related immune patterns, muscle inflammation, thyroid autoimmunity, kidney and urine involvement, liver safety, nutrient status, methylation, and metabolic inflammation.

During a provider review, you can discuss whether results suggest follow-up testing, repeat testing, rheumatology referral, gastroenterology review, kidney follow-up, medication review, nutrition changes, or additional clinical evaluation.


Additional Panels to Consider

Customers interested in the Inflammation, Autoimmune & Chronic Pain - Advanced Lab Panel may also consider:

  • Inflammation, Autoimmune & Chronic Pain - Essential Lab Panel
  • Inflammation, Autoimmune & Chronic Pain - Comprehensive Lab Panel
  • Fatigue, Low Energy & Brain Fog Lab Panel
  • Thyroid & Metabolism Lab Panel
  • Vitamin, Mineral & Nutrient Deficiency Lab Panel
  • Heavy Metals & Environmental Toxins Lab Panel
  • Gut Health, Food Allergy & Nutrient Lab Panel
  • Prediabetes & Insulin Resistance Lab Panel
  • Medication & Supplement Safety Lab Panel
  • Longevity & Healthy Aging Lab Panel

FAQ: Inflammation, Autoimmune & Chronic Pain - Advanced Lab Panel

What is the Inflammation, Autoimmune & Chronic Pain Advanced Lab Panel?

The Inflammation, Autoimmune & Chronic Pain Advanced Lab Panel is a broad blood and urine test panel that includes 41 tests and 138 biomarkers to evaluate inflammation, autoimmune screening, lupus-related markers, rheumatoid arthritis markers, Sjögren’s antibodies, celiac-related immune markers, muscle pain markers, thyroid autoimmunity, kidney and urine findings, nutrients, methylation, recovery, and metabolic inflammation.

Does this panel diagnose autoimmune disease?

No. This panel does not diagnose autoimmune disease by itself. Results should be interpreted by a licensed healthcare provider using symptoms, exam findings, medical history, family history, and follow-up testing when appropriate.

What autoimmune markers are included?

This panel includes ANA screen with reflex titer and pattern, dsDNA antibody, Sm and Sm/RNP antibodies, Sjögren’s SS-A/SS-B antibodies, complement C3/C4, rheumatoid factor, and CCP antibody.

What inflammation markers are included?

This panel includes C-Reactive Protein, hs-CRP, and Sed Rate by Modified Westergren, also called ESR.

Why are CK, aldolase, and LD included?

CK, aldolase, and LD may provide muscle inflammation, muscle injury, tissue turnover, statin-associated muscle symptom, or recovery context.

Why are kidney and urine markers included?

Autoimmune and inflammatory patterns can sometimes involve the kidneys. Cystatin C, urine albumin/creatinine, urine protein/creatinine, and urinalysis help provide kidney and urine context.

Why is the celiac panel included?

Celiac-related immune activity may overlap with chronic pain, fatigue, anemia, nutrient deficiencies, digestive symptoms, joint pain, and autoimmune clustering.

Why are thyroid markers included?

Thyroid dysfunction and thyroid autoimmunity can overlap with fatigue, muscle pain, weakness, mood symptoms, weight changes, and autoimmune patterns.

Why are B12, folate, MMA, B6, homocysteine, zinc, selenium, magnesium, and vitamin D included?

These nutrients and methylation markers may provide context for fatigue, nerve symptoms, immune function, inflammation balance, muscle function, recovery, and overall wellness.

Should I choose Essential, Advanced, or Comprehensive?

Choose Essential for a focused inflammation and joint-pain baseline, Advanced for deeper autoimmune and chronic pain context, and Comprehensive for the broadest autoimmune, lupus, rheumatoid, antiphospholipid, Sjögren’s, celiac, muscle, thyroid, kidney, nutrient, omega, and metabolic inflammation review.


Important Note

This panel is designed to help evaluate selected biomarkers related to inflammation, autoimmune patterns, chronic pain, joint pain, muscle pain, thyroid autoimmunity, kidney involvement, nutrient status, metabolic inflammation, and general wellness. It is not intended to diagnose, treat, cure, or prevent disease by itself. Results should be reviewed with a licensed healthcare provider.

Customer Reviews