The Clotting Factor VIII Activity Test measures the activity of factor VIII, a protein essential for normal blood clotting. Low activity may indicate hemophilia A or acquired deficiencies, while elevated activity is linked to clotting risk. This test helps evaluate unexplained bleeding, bruising, or thrombosis, and supports diagnosis of inherited or acquired clotting disorders, providing insight into overall hemostatic function.

The von Willebrand Factor Antigen Test measures the amount of von Willebrand factor, a blood protein essential for clotting. Low levels may indicate von Willebrand disease, the most common inherited bleeding disorder, while elevated levels can occur with inflammation or pregnancy. Doctors use this test to evaluate unexplained bleeding, frequent nosebleeds, or heavy menstrual periods and to guide diagnosis and management of clotting disorders.

The Vascular Endothelial Growth Factor (VEGF) Test measures VEGF levels in blood to assess abnormal blood vessel growth and vascular health. Elevated VEGF may be associated with cancers, macular degeneration, diabetic retinopathy, or inflammatory disorders. Doctors use this test to evaluate angiogenesis activity, investigate unexplained vision changes or tumor growth, and guide treatment strategies for cancer or vascular-related conditions.

The Prothrombin (Factor II) 20210G→A Mutation Analysis Test detects a genetic variant in the prothrombin gene linked to increased risk of abnormal blood clotting. This mutation is associated with venous thromboembolism, deep vein thrombosis, and pulmonary embolism. Identifying this mutation helps evaluate inherited thrombophilia, supporting risk assessment, family studies, and management of clotting disorders.

The Rheumatoid Factor IgA Antibody Test measures IgA-class rheumatoid factor, an autoantibody linked to rheumatoid arthritis and other autoimmune diseases. Elevated levels may indicate joint inflammation, Sjögren’s syndrome, or chronic infections. Doctors use this blood test alongside other markers to confirm diagnosis, assess disease activity, and guide treatment decisions for patients with suspected autoimmune or inflammatory disorders.

The Rheumatoid Factor IgG Antibody Test measures IgG-class rheumatoid factor, an autoantibody often linked to rheumatoid arthritis and autoimmune diseases. Elevated levels may indicate joint inflammation, Sjögren’s syndrome, or chronic infection. Doctors use this test with other markers to confirm diagnosis, assess autoimmune activity, and guide treatment for patients with persistent joint pain, swelling, or suspected inflammatory disorders.

The Factor V Leiden Mutation Analysis detects a genetic mutation in the F5 gene that increases risk of abnormal blood clotting (thrombophilia). Individuals with this mutation may be prone to deep vein thrombosis (DVT), pulmonary embolism, or pregnancy complications. Doctors use this DNA test to confirm inherited clotting disorders, assess family risk, and guide prevention strategies, including anticoagulation or lifestyle management.

The Rheumatoid Factor IgA IgG IgM Antibodies Test measures multiple rheumatoid factor classes to aid in diagnosing rheumatoid arthritis and related autoimmune diseases. Elevated levels may suggest joint inflammation, Sjögren’s syndrome, lupus, or chronic infections. Doctors use this comprehensive test to confirm autoimmune involvement, investigate persistent pain or stiffness, and guide treatment planning by assessing disease activity across antibody types.

The Rheumatoid Factor (RF) Test measures RF antibodies in blood to help diagnose rheumatoid arthritis and other autoimmune conditions. High RF levels may indicate rheumatoid arthritis, Sjögren’s syndrome, or other connective tissue diseases, though they can also appear in some infections. Doctors order this test to investigate joint pain, stiffness, or swelling. Results provide important insight into autoimmune activity, joint health, and inflammatory disease management.

The Rheumatoid Factor IgM Antibody Test measures IgM rheumatoid factor, the most common autoantibody linked to rheumatoid arthritis. Elevated levels may indicate autoimmune activity, Sjögren’s syndrome, or chronic infections. Doctors use this test to help diagnose rheumatoid arthritis, investigate joint pain, swelling, or stiffness, and monitor disease progression. Results are often combined with other antibody tests for accurate evaluation and treatment planning.

The Intrinsic Factor Blocking Antibody Test detects antibodies that interfere with intrinsic factor, a protein essential for vitamin B12 absorption. The presence of these antibodies is strongly associated with pernicious anemia, an autoimmune cause of B12 deficiency. Doctors use this blood test to help confirm diagnosis, distinguish the cause of anemia, and guide treatment for patients experiencing fatigue, weakness, or neurological symptoms related to low B12.

The Tumor Necrosis Factor-Alpha (TNF-α) Test measures levels of this cytokine, a key marker of inflammation and immune system activity. Elevated TNF-α may indicate autoimmune disease, chronic inflammation, sepsis, or certain cancers. Doctors order this test for patients with rheumatoid arthritis, Crohn’s disease, or persistent fever. Results provide critical insight into immune dysregulation, disease progression, and response to anti-inflammatory therapies.

The von Willebrand Factor Collagen Binding Assay Test evaluates the ability of von Willebrand factor (VWF) to bind collagen, a key step in platelet adhesion and clot formation. Abnormal results may indicate qualitative von Willebrand disease or dysfunction affecting hemostasis. This assay provides insight into bleeding disorders, supporting diagnosis and management of patients with abnormal clotting, bruising, or mucosal bleeding.