Hepatitis

Hepatitis tests check for viral infections that inflame the liver—most often hepatitis A (HAV)hepatitis B (HBV), and hepatitis C (HCV). Less common types include hepatitis D (HDV) and hepatitis E (HEV). Because symptoms can be mild or absent, lab testing is the best way to know if you have a current infectionpast infection, or immunity from vaccination.

A proactive plan pairs screening tests (e.g., HBsAg, anti-HBs, anti-HBc for HBV; HCV antibody with reflex to RNA) with confirmatory tests (viral RNA/DNA) and a hepatic function panel (AST/ALT, bilirubin, ALP/GGT, albumin) to assess liver injury. Add targeted tests—HAV IgM for acute hepatitis, HDV when HBsAg is positive, or HEV in select travel/pregnancy settings. These labs support screeningdiagnostic triage, and monitoring, but they do not replace a clinician’s exam, imaging, or urgent care for severe symptoms.

Signs, Symptoms & Related Situations

  • Common symptoms: fatigue, low appetite, nausea, abdominal discomfort (right upper side), dark urine, pale stools, jaundice (yellow skin/eyes)

  • Risk & exposure: blood or body-fluid exposure, shared needles, unregulated tattoos/piercings, birth to an infected parent, household/sexual exposure, travel to endemic regions, under-immunization

  • Medication & alcohol: heavy alcohol use or liver-affecting medicines/supplements can worsen injury

  • Pregnancy: hepatitis screening is part of routine prenatal care

  • When to seek urgent care: confusion, severe abdominal swelling/pain, vomiting blood or black stools, intense jaundice with fever, or trouble breathing

Symptoms and risks should be evaluated by a qualified clinician.

Why These Tests Matter

What testing can do

  • Detect current infection (e.g., HBsAg, HCV RNA, HAV IgM) and confirm immunity (e.g., anti-HBs, total anti-HAV)

  • Differentiate phases of infection (acute vs. chronic) using core antibodies and viral load

  • Guide next steps by pairing infection status with liver chemistry (AST/ALT, bilirubin) and safety labs

What testing cannot do

  • Diagnose cirrhosis or cancer on labs alone—imaging/elastography (and sometimes biopsy) may be needed

  • Replace a clinician’s judgment on timing, repeat testing after exposure, or public-health reporting when required

  • Provide treatment or dosing advice—review results with your clinician

What These Tests Measure (at a glance)

  • Hepatitis B (HBV)

    • HBsAg: surface antigencurrent HBV infection.

    • Anti-HBs (HBsAb): surface antibodyimmunity from vaccination or recovery.

    • Anti-HBc (total/IgM): core antibodypast or current infectionIgM supports acute infection.

    • HBeAg / anti-HBe: replication/activity context (clinician-directed).

    • HBV DNA (quantitative PCR): measures viral load; monitors activity.

  • Hepatitis C (HCV)

    • HCV Antibody: screening test; a reactive result needs HCV RNA to confirm current infection.

    • HCV RNA (quantitative PCR): confirms active infection and measures viral load.

    • (Optional) Genotype: sometimes used in specialist care.

  • Hepatitis A (HAV)

    • HAV IgM: acute/recent infection.

    • Total anti-HAV (IgG ± IgM): immunity from past infection or vaccination.

  • Hepatitis D (HDV)

    • HDV Ab / HDV RNA: test only if HBsAg is positive (HDV requires HBV).

  • Hepatitis E (HEV)

    • HEV IgM/IgG: consider with compatible illness, travel, or certain pregnancy settings.

  • Liver & safety context

    • AST/ALT, ALP/GGT, bilirubin, albuminPT/INRplateletscreatinine/sodium to gauge injury, function, and risk.

Quick Build Guide

Clinical goal Start with Add if needed
General screening HBV triple panel (HBsAg, anti-HBs, total anti-HBc) • HCV Ab with reflex to RNA Hepatic function panel
Abnormal liver enzymes HBV triple panel • HCV Ab→RNA HAV IgM (acute), HEV IgM(travel/pregnancy), HDV if HBsAg+
Documenting immunity Anti-HBs (HBsAb) • Total anti-HAV Full HBV triple if prior status unknown
Suspected acute hepatitis HAV IgM • HBc IgM • HBsAg • HCV RNA Hepatic panel • PT/INRHEV IgM in select cases
Known HBsAg positive HBeAg/anti-HBe • HBV DNA HDV Ab/RNA based on risk
Recent blood/body-fluid exposure HBV triple panel • HCV Ab→RNA Hepatic panel; follow clinician guidance on repeats

How the Testing Process Works

  1. Match tests to your goal: screening, documenting immunity, or evaluating symptoms/abnormal labs.

  2. Provide samples: standard blood draw; no fasting unless lipids are added.

  3. Understand timing: early after exposure, antibody tests may be negative; RNA/DNA tests can detect infection earlier.

  4. View results securely: most values post within a few days.

  5. Plan next steps: review with your clinician; repeat or add tests based on timing and risk, and arrange imaging if needed.

Interpreting Results (General Guidance)

  • HBV

    • HBsAg positive: current infection.

    • Anti-HBs positive, anti-HBc negative: vaccine immunity.

    • Anti-HBc positive (± anti-HBs), HBsAg negative: past infection; context matters.

    • HBc IgM positive: supports acute infection.

    • HBV DNA: higher levels indicate more active replication.

  • HCV

    • HCV Ab reactive + RNA detected: current infection.

    • HCV Ab reactive + RNA not detected: past/resolved infection (or false positive); repeat if timing is uncertain.

    • High suspicion with Ab negative: consider HCV RNA early after exposure.

  • HAV/HEV

    • IgM positive: recent/acute infection.

    • Total anti-HAV or HEV IgG positive: past exposure or immunity (HAV).

  • Liver tests

    • ALT/AST and bilirubin elevated: show liver injuryINR/albumin reflect synthetic function.
      Always interpret patterns and timing with a qualified healthcare professional.

Choosing Panels vs. Individual Tests

  • Screening set (most adults): HBV triple panel + HCV Ab with reflex RNA

  • Immunity check: Anti-HBs (± total anti-HAV); add full HBV triple if history unclear

  • Symptomatic/acute work-up: HAV IgM • HBc IgM • HBsAg • HCV RNA • Hepatic panel • PT/INR

  • HBsAg-positive follow-up: HBeAg/anti-HBe • HBV DNA (and HDV when appropriate)

FAQs

Do I need to fast for hepatitis tests?
No. These are standard blood tests; fast only if your order includes lipids.

What does a “reactive” HCV antibody mean?
It means exposure at some point—HCV RNA shows whether infection is current.

Which test proves HBV immunity?
Anti-HBs (HBsAb) confirms immunity, usually from vaccination or recovery.

Can hepatitis be present with normal liver enzymes?
Yes. Enzymes can fluctuate or be normal in some phases—screening still matters.

How soon after exposure should I test?
RNA/DNA tests can detect infection earlier than antibody tests. Your clinician may repeat labs over several weeks.

If I’m HBsAg positive, do I need other tests?
Often yes—HBV DNA and HBeAg/anti-HBe help assess activity; HDV testing is considered in some cases.

Will vaccination make infection tests positive?
Vaccines can make immunity markers (e.g., anti-HBs) positive, but do not make HBsAg or HCV RNA positive.

Related Categories & Key Tests

  • Liver & Gallbladder Tests Hub

  • Hepatic Function Tests • Cirrhosis Tests • Fatty Liver (Metabolic) • Autoimmune Liver Disease • Hemochromatosis • Wilson’s Disease • All Infectious Disease Tests

  • Key Tests: HBsAg • Anti-HBs (HBsAb) • Total anti-HBc • HBc IgM • HBeAg/anti-HBe • HBV DNA (quantitative PCR) • HCV Antibody • HCV RNA (quantitative PCR) • HCV Genotype (as directed) • HAV IgM • Total anti-HAV • HDV Ab/RNA (HBsAg-positive only) • HEV IgM/IgG • Hepatic Function Panel (AST, ALT, ALP, GGT, Bilirubin, Albumin) • PT/INR • Platelets/CBC

References

  • Centers for Disease Control and Prevention — Hepatitis A, B, C testing recommendations.
  • U.S. Preventive Services Task Force — Screening for Hepatitis B and C.
  • American Association for the Study of Liver Diseases — HBV and HCV guidance.
  • World Health Organization — Viral hepatitis testing policies.
  • European Association for the Study of the Liver — Clinical practice guidelines on viral hepatitis.
  • Clinical reviews on interpretation of hepatitis serologies and reflex RNA/DNA testing.

Available Tests & Panels

Your Hepatitis Tests menu is pre-populated in the Ulta Lab Tests system. Use filters to build the right package—HBV triple panelHCV antibody with reflex to RNAHAV IgM/totalHDV/HEV when indicated, and a hepatic function panel to assess liver injury. Review results with your clinician to plan any repeat testing, imaging, or follow-up.

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Name Matches

The Actin Smooth Muscle IgG Antibody Test detects autoantibodies against smooth muscle actin, often linked to autoimmune hepatitis and chronic liver disease. Elevated levels may indicate liver inflammation, cirrhosis, or other autoimmune conditions. Doctors use this blood test with liver panels and additional antibody tests to aid in diagnosis, monitor disease progression, and guide treatment decisions for patients with suspected autoimmune liver disorders.

Blood
Blood Draw
Also Known As: Actin IgG Antibody Test

The Acute Hepatitis Panel with Reflex to Confirmation detects recent or acute infection by hepatitis A (IgM), B (surface antigen, core IgM), and C (antibody with reflex to RNA PCR) using immunoassay. Reflex confirmation ensures accurate diagnosis for hepatitis B surface antigen positives and reactive HCV antibodies. Use is indicated for symptomatic patients with jaundice, dark urine, fatigue, abdominal pain, or elevated liver enzymes.

Also Known As:

Hepatitis Panel Acute with Reflex to Confirmation


The Albumin Test measures albumin, the main protein made by the liver that maintains fluid balance and transports hormones, vitamins, and medications. Low albumin may indicate liver disease, kidney problems, malnutrition, or chronic inflammation, while high levels may reflect dehydration. Doctors order this test to evaluate swelling, fatigue, or abnormal labs. Results provide key insight into nutritional status, liver and kidney function, and overall metabolic health.

Blood
Blood Draw
Also Known As: ALB Test

The Aldolase Test measures levels of aldolase, an enzyme involved in breaking down glucose for energy. Elevated levels may indicate muscle damage, muscular dystrophy, polymyositis, dermatomyositis, or certain liver diseases. Doctors use this blood test to help diagnose and monitor muscle disorders, evaluate unexplained weakness, and track treatment response. It is often ordered alongside CK and other enzyme tests for a complete evaluation of muscle health.

Blood
Blood Draw

The ALP Test measures alkaline phosphatase enzyme levels in blood to evaluate liver, bone, and bile duct health. High ALP may indicate liver disease, bile duct obstruction, bone disorders, or certain cancers, while low levels may suggest malnutrition or deficiency. Doctors order this test to investigate symptoms like fatigue, abdominal pain, or bone pain and often pair it with other liver function tests. Results provide key insight into metabolic and organ health.

Blood
Blood Draw
Also Known As: Alkaline Phosphatase Test, Alk Phos Test, Alkp Test

The Alpha-Fetoprotein (AFP) and AFP-L3 Test measures total AFP and the AFP-L3 fraction, which is more specific for liver cancer risk. Elevated AFP may indicate liver disease, germ cell tumors, or hepatitis, while AFP-L3 is strongly associated with hepatocellular carcinoma (HCC). Doctors order this test to assess liver function, screen high-risk patients, and monitor cancer treatment. Results provide critical insight into liver health and cancer detection.

Blood
Blood Draw
Also Known As: AFP Test, Total AFP Test, Alpha-Fetoprotein Tumor Markers, Alpha-Fetoprotein Test

The ALT Test measures alanine aminotransferase, an enzyme mainly found in the liver. Elevated ALT may indicate liver damage from hepatitis, fatty liver disease, cirrhosis, alcohol use, or medication effects. Doctors order this test to evaluate symptoms such as fatigue, abdominal pain, or jaundice and often pair it with AST for accurate liver assessment. Results provide essential insight into liver health, enzyme activity, and overall metabolic function.

Blood
Blood Draw
Also Known As: Alanine Aminotransferase Test, GPT Test, SGPT Test, Serum Glutamic Pyruvic Transaminase Test

The Ammonia Plasma Test measures ammonia levels in blood to evaluate liver function and metabolic health. Elevated ammonia may result from liver disease, cirrhosis, Reye’s syndrome, or urea cycle disorders, causing confusion or altered mental status. Doctors order this test for patients with unexplained behavioral changes, lethargy, or suspected hepatic encephalopathy. Results provide key insight into liver function, metabolic disorders, and treatment monitoring.

Blood
Blood Draw
Also Known As: NH3 Test, NH3 Plasma Test, Ammonia Blood Test

The ANA IFA Panel Comprehensive screens for autoimmune disorders by detecting antinuclear antibodies and specific markers including dsDNA, Sm, Sm/RNP, Scl-70, and Sjögren’s SS-A/SS-B. Doctors order this panel for patients with joint pain, rash, fatigue, or suspected lupus, scleroderma, or Sjögren’s syndrome. Results provide critical insight into autoimmune activity, helping confirm diagnosis, monitor disease progression, and guide treatment decisions.

Also Known As: Comprehensive ANA Panel

The ANA Screen IFA with Reflex to Titer and Pattern Test detects antinuclear antibodies in blood to evaluate autoimmune activity. If positive, further testing identifies antibody concentration (titer) and fluorescence pattern, helping diagnose conditions like lupus, rheumatoid arthritis, or Sjögren’s syndrome. Doctors order this test to investigate symptoms such as joint pain, fatigue, rash, or swelling and to guide treatment for autoimmune and connective tissue disorders.

Also Known As: ANA Test, Antinuclear Antibody Screen Test

The AST Test measures aspartate aminotransferase, an enzyme found in the liver, heart, muscles, and other tissues. Elevated AST may indicate liver disease, heart attack, muscle injury, or other organ damage. Doctors order this test to evaluate symptoms such as fatigue, weakness, or jaundice and often pair it with ALT for accurate liver assessment. Results provide key insight into liver function, muscle health, and overall metabolic balance.

Blood
Blood Draw
Also Known As: Aspartate Aminotransferase Test, Serum Glutamic-Oxaloacetic Transaminase Test, SGOT Test

A comprehensive blood test designed to evaluate autoimmune causes of liver inflammation. The Autoimmune Hepatitis Diagnostic Panel measures ANA, mitochondrial antibodies, smooth muscle antibodies, and LKM-1 antibodies to help identify autoimmune hepatitis and related liver disorders. Ideal for investigating unexplained elevated liver enzymes and suspected immune-mediated liver disease.


The Bilirubin Direct Test measures conjugated bilirubin in the blood to assess liver function and bile duct health. Elevated levels may indicate hepatitis, cirrhosis, gallstones, or bile duct obstruction, while low levels are generally normal. Doctors order this test for patients with jaundice, fatigue, or suspected liver disease. Results help diagnose and monitor liver disorders, guide treatment decisions, and evaluate overall hepatic and biliary health.

Blood
Blood Draw
Also Known As: Direct Bilirubin Test

The Fractionated Bilirubin Test separates total bilirubin into direct and indirect forms to assess liver and blood health. Elevated direct bilirubin may point to hepatitis, cirrhosis, or bile duct obstruction, while elevated indirect levels can signal hemolytic anemia or inherited disorders. Doctors order this test for jaundice, anemia, or suspected liver conditions. Results help guide diagnosis, treatment, and monitoring of liver and blood disorders.

Blood
Blood Draw
Also Known As: Fractionated Bilirubin Test

The Bilirubin Total Test measures the overall level of bilirubin in blood to assess liver function, red blood cell breakdown, and bile duct health. Elevated bilirubin may cause jaundice and indicate hepatitis, cirrhosis, gallstones, or hemolytic anemia. Doctors order this test for patients with yellowing skin, fatigue, or abnormal liver results. Results provide essential insight into liver disease, blood disorders, and bile flow problems, guiding diagnosis and treatment.

Blood
Blood Draw
Also Known As: Total Bilirubin Test

The Carbohydrate-deficient Transferrin Test measures abnormal transferrin isoforms in the blood, which can indicate chronic alcohol consumption or alcohol use disorder. By detecting elevated CDT levels, the test helps assess patterns of heavy drinking and monitor abstinence or relapse. Clinicians may also use results to support evaluation of liver function and alcohol-related health risks, providing valuable insight into long-term alcohol exposure.

Blood
Blood Draw
Also Known As: Alcohol Use Test

Most Popular

The Cyclic Citrullinated Peptide (CCP) IgG Antibody Test helps diagnose rheumatoid arthritis by detecting antibodies strongly linked to autoimmune joint disease. A positive result may indicate early or developing RA, even before symptoms appear. Doctors order this test for patients with joint pain, stiffness, or swelling. Results, often used with the rheumatoid factor (RF) test, provide valuable insight into autoimmune activity and long-term joint health management.

Blood
Blood Draw
Also Known As: Anti-CCP, Cyclic Citrullinated Peptide IgG Antibody Test

The Ceruloplasmin Test measures levels of ceruloplasmin, a copper-carrying protein made in the liver, to evaluate copper metabolism and related disorders. Low levels may indicate Wilson’s disease, Menkes disease, or severe liver disease, while high levels may suggest inflammation or pregnancy. Doctors order this test for patients with liver problems, neurological symptoms, or abnormal copper levels. Results help diagnose metabolic disorders and guide treatment.

Blood
Blood Draw
Also Known As: Copper Oxide Test, Wilson’s Disease Test

The Comprehensive Metabolic Panel (CMP) Test measures 21 markers to assess metabolic health, liver and kidney function, and electrolyte balance. It includes glucose, calcium, sodium, potassium, chloride, CO2, albumin, globulin, A/G ratio, total protein, bilirubin, ALP, AST, ALT, BUN, creatinine, BUN/creatinine ratio, and eGFR. The CMP helps detect diabetes, liver or kidney disease, and supports routine screening and chronic condition monitoring.

Blood
Blood Draw
Also Known As: CMP Test, Chemistry Panel Test, Chem Test, Chem 21 Test, Chem 14 Test 

The Comprehensive Sjögren’s Syndrome Diagnostic Panel evaluates key autoimmune markers including ANA with reflex to titer, SS-A and SS-B antibodies, rheumatoid factor, thyroid peroxidase antibody, and mitochondrial antibody with reflex. This blood test helps diagnose Sjögren’s syndrome, an autoimmune disease affecting tear and saliva glands, while also detecting related autoimmune or connective tissue disorders to guide treatment and patient care.

Also Known As: Sjögren's Syndrome Diagnostic Panel Comprehensive

The Copper Blood Test measures copper levels in the blood to evaluate nutritional status, metabolic function, and potential toxicity. Abnormal levels may be linked to Wilson’s disease, Menkes disease, liver dysfunction, or excessive exposure. This test helps assess unexplained fatigue, neurological symptoms, or metabolic imbalance, supporting evaluation of trace element health and copper-related disorders.

Blood
Blood Draw
Also Known As: Cu Blood Test, Cu Test, Blood Copper Test, Hepatic Copper Test, Copper Free Test

This test measures AST, ALT, and Platelet Count to help you calculate your own FIB-4 Index — a non-invasive indicator of liver health and fibrosis risk.

Serum, Blood
Phlebotomist

The General Hepatitis Panel Test screens for multiple hepatitis infections in one order. It includes Hepatitis A Antibody Total, Hepatitis B Surface Antibody Qualitative, Hepatitis B Surface Antigen with Reflex to Confirmation, Hepatitis B Core Antibody Total, and Hepatitis C Antibody with Reflex to RNA PCR. Doctors use this panel to detect past exposure, confirm active or chronic infection, guide treatment, and support liver health monitoring.

Also Known As: Hepatitis Panel General

Most Popular

The GGT Test measures gamma-glutamyl transferase, an enzyme found in the liver and bile ducts, to evaluate liver health. Elevated GGT may indicate liver disease, bile duct obstruction, alcohol use, or medication side effects. Doctors order this test to investigate symptoms like fatigue, jaundice, dark urine, or abdominal pain and to monitor liver damage. It is often performed with other liver tests to provide a complete picture of liver and bile duct function.

Blood
Blood Draw
Also Known As: Gamma Glutamyl Transferase Test, Gamma Glutamyl TransPeptidase Test, GGTP Test, GTP Test

The Hep B Test, a Hepatitis B Surface Antigen Test with Reflex to Confirmation, screens for active hepatitis B infection by detecting HBsAg in the blood. A reflex confirmation is performed if the initial result is positive, ensuring accuracy. Doctors use this test to diagnose current infection, monitor at-risk patients, and prevent transmission. It is essential for evaluating liver health, guiding treatment, and supporting safe medical or prenatal care.

Blood
Blood Draw

Whether you’ve traveled outside the country for mission work or signed a consent form to get a tattoo, chances are you’ve heard about hepatitis before. Most of us have the general idea that there are different varieties and that some are worse than others. But which ones are the bad ones, and how do we tell if we have any of them?

The truth is that most adults will get exposed to some strain of hepatitis at some point in their lives. Knowing which strains are dangerous and when you should have hepatitis testing performed could save your life. Read on to learn more about hepatitis and the tests you can have run to screen for it.

What Is Hepatitis?

Hepatitis is a disease that causes your liver to get inflamed. It is caused by viruses and comes in three primary forms: hepatitis A, hepatitis B, and hepatitis C. The three strains vary in how dangerous and long-lasting they are.

Your liver is the largest organ in your body and helps digest food and store energy. It also forms the center of your body’s detox system, meaning you never have to do another juice cleanse again. As long as it’s healthy, your liver can take care of removing any dangerous toxins from your body.

When you develop hepatitis, you may see several symptoms depending on the strain you have. Common symptoms include loss of appetite, nausea, vomiting, diarrhea, stomach pain, and jaundice. There are vaccines you can get against certain strains of hepatitis, so be sure you’re up to date on those.

Hepatitis A 

Hepatitis A is a highly infectious viral infection and is the easiest of the strains to get. You can pick up Hepatitis A from food or water contaminated with the virus or from close contact with an infected person. There is a vaccine available to prevent this disease, and washing your hands is a great way to keep it from spreading.

Hepatitis A is the most minor of the strains, and some people who get it never develop symptoms. If you do get symptoms, you may notice you’re more fatigued, you may have sudden nausea or vomiting, or you may have pain in the upper right side of your abdomen. You may also have a low-grade fever, clay-colored bowel movements, or dark-colored urine.

In many cases, hepatitis A will resolve on its own with no treatment needed. It’s a good idea to see your doctor if you develop symptoms or if you’ve been recently out of the country to an area with poor sanitation. Most people who get hepatitis A will recover with no lasting liver damage.

Hepatitis B

Hepatitis B is a more serious form of the disease that usually lasts about six months. This disease passes through bodily fluid contact, especially during sexual interactions. You can also get hepatitis B from sharing infected needles (including tattooing needles) or through medical syringes contaminated with infected blood.

Hepatitis B symptoms can show up anywhere from one month to four months after exposure. You may notice abdominal pain, fever, dark urine, or joint pain. You may also lose your appetite, experience nausea and vomiting, feel weak and fatigued, and have abdominal pain.

In most cases, hepatitis B will resolve within six months with treatment. Sometimes, however, complications can arise that lead to a chronic infection. This chronic form of the disease can lead to liver scarring (cirrhosis) and even liver cancer, so it’s important to make sure you get a hepatitis B vaccine.

Hepatitis C

Hepatitis C is the most dangerous form of the disease, and it is also the hardest to get. The virus spreads through infected blood, putting healthcare workers and drug users at the biggest risk. The most common way that the disease passes is through infected needles, so make sure you always use clean needles.

The dangerous thing about hepatitis C is it can be a silent killer. In many cases, people won’t show symptoms of hepatitis C until they start seeing signs of the liver damage it’s inflicted. Symptoms include jaundice (a yellowing of the skin and eyes), bruising or bleeding easily, poor appetite, itchy skin, swelling in your legs, fatigue, and spider-like veins on your skin.

Treatments for chronic hepatitis C have significantly improved over the past several years, and these days, the condition is almost always curable. Treatments involve oral medications taken for a few months. The key is catching it before it does serious damage to your liver.

Who’s at Risk?

In most cases, hepatitis transmits through contact with infected blood. This means some of the highest risk populations are people who use injectable drugs. If you fall into this category, reach out to someone to help you get clean or always use clean needles.

Health care workers are also at risk since they handle blood from potentially infected people. Nurses who perform blood draws may be at a higher risk than healthcare workers who travel to or work in areas with poor sanitation. 

People with tattoos and piercings could also encounter infected needles. If you’re getting a tattoo or piercing, always do so at a reputable, clean location. Ask the tattooist or piercer to let you watch them open a new needle to be sure they aren’t reusing old needles. 

When to Get Tested

The most important time to get tested for hepatitis is as soon as possible after exposure. This includes after you’ve used a dirty needle, gotten a piercing or tattoo, visited an unsanitary location, or had sex with someone who has done any of the above.

If you are pregnant or planning on becoming pregnant, testing for hepatitis B is very important. Hepatitis B can pass from mother to child during childbirth, and in infants, it’s more likely to develop into a chronic condition. However, newborns can receive a vaccine against hepatitis B that will prevent infection in almost all cases. Without the vaccine, 90 percent of newborns develop chronic hepatitis.  

You should also get tested for hepatitis if you start showing any of the symptoms we’ve mentioned above. In particular, jaundice is usually a sign of liver damage, so pay attention to that. Hepatitis C may only show symptoms for a couple of weeks before fading into the background, so don’t ignore an illness because it goes away.

How Often to Get Tested

In general, it’s a good rule of thumb to get tested for hepatitis if you think you’ve been exposed to the virus any time in the last six months. If you face exposure regularly for any reason, you may need to get routine testing.

The CDC recommends routine testing every six months for people who have transplanted tissue. People who use drugs, including snorting cocaine, and using other non-injectable drugs, should get tested routinely. A routine screen should also be a habit for anyone who has multiple sexual partners or a long-term sexual relationship with someone who has tested positive for hepatitis, especially hepatitis C.

If you are pregnant, a healthcare worker, or have nonsexual contact with someone with hepatitis C; you need to have routine screenings. If you are pregnant, one screening at the beginning of your pregnancy will be fine. And, of course, if you are potentially exposed or start showing symptoms, get tested immediately.

Hepatitis A Testing

If you believe you have been exposed to hepatitis A, you can get a screening done for this strain. There are two main antibodies this test checks for: IgM and IgG. The body first produces IgM antibodies about two or three weeks after infection, often before symptoms start to show up.

If any IgM antibodies show up on your screen, it means you have or have had recent acute hepatitis A. If your IgM test comes back negative, you may want to run an IgG test, as IgG antibodies show up later in the disease process and stay in your bloodstream for life. If your IgG test comes back positive, it means you have had hepatitis A at some point in the past.

It’s important to note that if you’ve ever received a hepatitis A immunization, you will have the IgG antibodies in your bloodstream since that’s how your body fights off the infection. Even if you haven’t had the immunization, you may still see those antibodies show up; about 30 percent of American adults carry IgG antibodies. In the case of IgM tests, IgG tests, and total antibody tests, which check for both antibodies, the screen will involve getting blood drawn.

Hepatitis B Testing

Hepatitis B panels look for proteins that the hepatitis virus produces in your body. They may also look for the antibodies your body produces to fight the virus or even the DNA of the virus itself. Depending on how your results come out, you can see if you currently have the virus, if you have had it in the past, or if you’ve had the immunization.

Suppose your hepatitis B surface antibody scan (Anti-HBs) comes back positive, but your core antibody total (Anti-HBc IgG IgM) comes back negative. In that case, it means you’ve had the vaccination but not the disease. If both tests come back positive, it means you’ve had the disease before and may be at risk of developing it again if your immune system is ever compromised.

If your surface antigen test (HBsAg) comes back positive, it means you currently have an active form of hepatitis B. A positive core antibody scan (Anti-HBc IgM) in combination with this result means you have an acute infection. A negative core antibody scan means your infection is chronic.

If you find out you have a chronic infection, you may choose to run a test for hepatitis B e antigens, and antibodies, as well as DNA from the hepatitis B virus. You are a disease carrier if your test comes back negative for the antigens and positive for the antibodies. You have the virus, but it’s not likely to do any liver damage. If the scan picks up on the hepatitis B virus DNA, chances are your chronic condition is causing damage to your liver. 

Hepatitis C Testing 

Hepatitis C tests look for one of two things: the antibodies your body produces to fight the virus or the RNA of the virus itself. Most of these scans look for the antibodies, with the RNA used as a backup measure. If your antibody scan is positive or inconclusive, the RNA scan can give you more information.

If your antibody test comes back negative, it can mean one of two things. Either you do not have the infection, or not enough time has passed for your body to produce detectable levels of antibodies. If you or your doctor suspects you may still have hepatitis C, you should wait a little longer and rerun the test.

If your antibody test comes back positive or indeterminate, you may run an RNA scan. If this test comes back negative, you may have had the infection in the past, but you do not have it now. If the RNA scan comes back positive, you have a current infection.

Additional Liver Testing

If any of your hepatitis screens come back positive, you’ll need to run some additional tests to determine if you have liver damage and to what extent, if so.

Your doctor may also want to look at your levels of bilirubin, albumin, and total protein. These are all connected with liver function and can fluctuate with severe liver damage.

Learn More About Hepatitis Testing

If you suspect you may have any hepatitis viruses, it’s a good idea to get a hepatitis test. Sure, hepatitis A is harmless enough, but it’s hard to tell the difference between a simple hepatitis A infection and a hepatitis C infection that can lead to serious liver damage. Hepatitis testing is the only way to know and your life is worth the investment.

If you’d like to get your hepatitis tests run, here are links to three Hepatitis tests that you can get select to get started:


Check out the rest of our site at ultalabtests.com, where we have over 2,000 lab tests, including the full spectrum of hepatitis screens available today.

We are here to help you know your health, one test at a time.