Hepatitis Screening

Our hepatitis testing will check to see if you have a hepatitis infection caused by viruses called hepatitis A, hepatitis B, and hepatitis C . Order your hepatitis screening today from Ulta Lab Tests and get your results confidentially online.


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Myasthenia Gravis (MG) is a neuromuscular disorder characterized by muscle weakness, most commonly due to autoantibody-mediated loss of functional acetylcholine receptors (AChR) in the neuromuscular junction. This assay aids in the differential diagnosis of MG-like muscle weakness, in differentiating between generalized MG and ocular MG, and in monitoring therapeutic response. If binding antibodies are negative, assays for blocking and modulating antibodies should be considered.

Myasthenia gravis (MG) is a neuromuscular disorder characterized by muscle weakness, most commonly due to autoantibody-mediated loss of functional acetylcholine receptors (AChR) in the neuromuscular junction. This assay is most useful when the acetylcholinesterase receptor modulating antibodies are positive. The assay for blocking antibodies is useful in monitoring response to therapy.

Myasthenia gravis (MG) is a neuromuscular disorder characterized by muscle weakness, most commonly due to autoantibody-mediated loss of functional acetylcholine receptors (AChR) in the neuromuscular junction. Modulating Antibody to AChR causes weakness by inhibiting or modulating binding to the receptors.

Actin is the major antigen to which smooth muscle antibodies react in autoimmune hepatitis. F-Actin IgG antibodies are found in 52-85% of patients with autoimmune hepatitis (AIH) or chronic active hepatitis and in 22% of patients with primary biliary cirrhosis (PBC). Anti-actin antibodies have been reported in 3-18% of sera from normal healthy controls.

IMPORTANT - The specimen for this test must be collected at a patient service center that can collect, store and transport frozen samples as outlined below.  

IMPORTANT: Before ordering this lab test, check and confirm with the selected patient service center to ensure that they can collect, store and transport frozen samples as outlined below.

Preferred Specimen(s) 

2 mL frozen plasma collected in an EDTA (lavender-top) tube

Collection Instructions 

Collect blood from stasis-free vein of patient (e.g., no tourniquet). Patient should not clench fist during collection, as muscular exertion often increases venous ammonia levels. Patient should avoid smoking prior to phlebotomy since smoking increases plasma ammonia levels. Tubes should be filled completely and kept tightly stoppered at all times. Place immediately on ice. Separate plasma from cells within 20 minutes and freeze plasma immediately.

Transport Temperature 

Frozen

Specimen Stability 

Room temperature: Unstable
Refrigerated: Unstable
Frozen -20° C: 72 hours
Frozen -70° C: 7 days

Reject Criteria 

Hemolysis • Lipemia • Received thawed • PPT Potassium EDTA (white-top) tube

Clinical Significance

Ammonia is one of the by-products of protein metabolism. Elevated blood ammonia levels have been associated with severe liver dysfunction such as hepatic encephalopathy, coma resulting from cirrhosis, severe hepatitis, Reye's syndrome, and drug hepatotoxicity. Also, elevated blood ammonia has been reported in cardiac failure, azotemia, and pulmonary emphysema. Correlation between plasma ammonia and the degree of encephalopathy can be erratic.


Antinuclear antibodies are associated with rheumatic diseases including Systemic Lupus Erythematous (SLE), mixed connective tissue disease, Sjogren's syndrome, scleroderma, polymyositis, CREST syndrome, and neurologic SLE. 

Reflex Information: If ANA Screen, IFA is positive, then ANA Titer and Pattern will be performed at an additional charge.



Decreased C3 may be associated with acute glomerulonephritis, membranoproliferative glomerulonephritis, immune complex disease, active systemic lupus erythematosis, and generalized autoimmune processes.

CH50 is a screening test for total complement activity. Levels of complement may be depressed in genetic deficiency, liver disease, chronic glomerulonephritis, rheumatoid arthritis, hemolytic anemias, graft rejection, systemic lupus erythematosis, acute glomerulonephritis, subacute bacterial endocarditis and cryoglobulinemia. Elevated complement may be found in acute inflammatory conditions, leukemia, Hodgkin's Disease, sarcoma, and Behcet's Disease.

These studies contribute to the diagnosis of autoimmune blistering diseases, dermatitis herpetiformis, and IgA vasculitis. Important in the evaluation of other autoimmune and inflammatory skin diseases including non-IgA vasculitides and interface and lichenoid dermatitis/mucositis such as connective tissue disorders, lichen planus, etc. The panel includes the C5b-9 antibody to better distinguish between some forms of Lupus and Dermatomyocitis. Its presence or absence is also critical in the evaluation of other types of connective tissue diseases and many vasculitides.

dsDNA Antibody is detected in patients with active systemic lupus erythematosus (SLE) and approximately 20% of patients with Mixed Connective Tissue Disease.

In conjunction with clinical findings and other laboratory tests, the high avidity dsDNA FARRZYME can be used as an aid to the diagnosis of systematic lupus erythematosus (SLE)

See individual tests

Hepatitis A Antibody, Total (IgM - IgG)

Hepatitis A Total (IgM - IgG) Blood Test is used to help diagnose a liver infection due to the hepatitis A virus. There are several causes of hepatitis and the accompanying symptoms, so this test may be used to determine if the symptoms are due to hepatitis A.

The total Hepatitis A antibody test detects both IgM and IgG antibodies and thus may be used to identify both current and past infections. This test will also be positive after receiving the vaccine, so sometimes it may be used to determine whether a person has developed immunity after vaccination.

  • A positive result Hepatitis A Antibody, Total that is not accompanied with Hepatitis A IgM test indicates  exposure to hepatitis A vairus but does not rule out acute infection. 
  • A Negative result Hepatitis A Antibody, Total that is not accompanied with Hepatitis A IgM test indicates no current or previous HAV infection; vaccine may be recommended if at risk.

Results of this hepatitis testing may indicate the following.

A total antibody test detects both IgM and IgG antibodies but does not distinguish between them.

If the total antibody test or hepatitis A IgG result is positive and someone has never been vaccinated against HAV, then the person has had past exposure to the virus. About 30% of adults over age 40 have antibodies to hepatitis A.


Hepatitis A IgM Antibody & Total A Antibody Panel conatins the following 2 tests.

  • Hepatitis A IgM Antibody
  • Hepatitis A Antibody, Total

This test is used to help diagnose a liver infection due to the hepatitis A virus. There are several causes of hepatitis and the accompanying symptoms, so this test may be used to determine if the symptoms are due to hepatitis A.

Hepatitis A Antibody, Total

The total Hepatitis A antibody test detects both IgM and IgG antibodies and thus may be used to identify both current and past infections. This test will also be positive after receiving the vaccine, so sometimes it may be used to determine whether a person has developed immunity after vaccination.

Hepatitis A IgM Antibody

The Hepatitis A IgM antibody test detects the first antibody produced by the body when it is exposed to hepatitis A. This test is used to detect early or recent infections and to diagnose the disease in people with symptoms of acute hepatitis. IgM antibodies to Hepatitis A suggest a current, acute or recent Hepatitis A infection.

Results of this hepatitis testing may indicate the following.

If Hepatitis A IgM Antibody is positive the resulkts indicate Acute or recent Hepatitis A virus infection.

If Hepatitis A IgM Antibody is negative and the Hepatitis A Antibody, Total is positive then the results indicate no active infection but previous Hepatitis A virus exposure; has developed immunity to Hepatitis A virus or recently vaccinated for Hepatitis A virus.


Hepatitis A IgM Antibody

This test is used to screen for recent exposure to the Hepatitis A virus.and to help diagnose a liver infection due to the Hepatitis A virus. There are several causes of hepatitis and the accompanying symptoms, so this test may be used to determine if the symptoms are due to Hepatitis A.

Hepatitis A IgM Antibody

The Hepatitis A IgM antibody test detects the first antibody produced by the body when it is exposed to Hepatitis A. This test is used to detect early or recent infections and to diagnose the disease in people with symptoms of acute hepatitis. IgM antibodies to Hepatitis A suggest a current, acute or recent Hepatitis A infection.

Results of this hepatitis testing may indicate the following:

  • If Hepatitis A IgM Antibody is positive the results indicate Acute or recent Hepatitis A virus infection.
  • If Hepatitis A IgM Antibody is negative and the Hepatitis A Antibody, Total is positive then the results indicate no active infection but previous Hepatitis A virus exposure; has developed immunity to Hepatitis A virus or recently vaccinated for Hepatitis A virus.
  • Dietary supplements containing biotin may interfere in assays and may skew analyte results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.

Hepatitis B Core Antibody (IgM) also known as (Anti-HBc, IgM)

Clinical Significance

Hepatitis B core-specific IgM class antibody has been detected in most acute infections and is a reliable marker for acute disease. In some cases, hepatitis B core IgM antibody may be the only specific marker for the diagnosis of acute infection with hepatitis B virus.

Alternative Name(s)

Anti-HBc, IgM

A Positive Result may indicate an Acute infection, usually with symptoms; contagious; could also be flare of chronic infection or Acute infection is resolving (convalescent). 


This assay does not distinguish between Total B core antibody IgG and IgM detected before or at the onset of symptoms; however, such reactivity can persist for years after illness, and may even outlast anti-HBs. Occasionally Hepatitis B core antibody may be the only marker of either current or past Hepatitis B infection.

Hepatitis B Surface Antibody, Qualitative  (anti-HBs)

Detects only the IgM antibody to the hepatitis B core antigen. Used to detect acute infections; sometimes present in chronic infections as well as used to detect previous exposure to HBV; it can also develop from successful vaccination so it is used to determine the need for vaccination (if anti-HBs is absent) or to determine if a person has recovered from an infection and is immune (cannot get the infection again).

Clinical Significance

The detection of anti-HBs is indicative of a prior immunologic exposure to the antigen or vaccine. To determine immune status as ≥10 mIU/mL as per CDC guidelines, please order Hepatitis B Surface Antibody, Quantitative.


Hepatitis B Surface Antibody, Quantitative (anti-HBs

Detects antibody produced in response to HBV surface antigen. It is used to detect previous exposure to HBV; it can also develop from successful vaccination so it is used to determine the need for vaccination (if anti-HBs is absent) or to determine if a person has recovered from an infection and is immune (cannot get the infection again).

Clinical Significance

This assay is used to determine immune status for Hepatitis B as ≥10 mIU/mL as per CDC Guidelines.


Hepatitis B Surface Antigen with Reflex Confirmation: Positive samples will be confirmed

IMPORTANT:  NOTE THIS IS A REFLUX TEST - The price charged for this test is only for the Hepatitis B Surface Antigen. ADDITIONAL CHARGES WILL OCCUR FOR THE REFLUX CONFIRMATION if the Hepatitis B Surface Antigen is positive.

Hepatitis B surface antigen (HBsAG) Detects protein that is present on the surface of the virus.  It is used to screen for, detect, and help diagnose acute and chronic hepatitis B virus (HBV) infections; earliest routine indicator of acute hepatitis B and frequently identifies infected people before symptoms appear; undetectable in the blood during the recovery period; it is the primary way of identifying those with chronic infections, including "hepatitis B virus (HBV) carrier" state.

Clinical Significance

Surface antigen usually appears in the serum after an incubation period of 1 to 6 months following exposure to Hepatitis B virus and peaks shortly after onset of symptoms. It typically disappears within 1 to 3 months. Persistence of Hepatitis B surface antigen for greater than 6 months is a prognostic indicator of chronic Hepatitis B infection.


Hepatitis Be Antibody - Hepatitis B surface antibody (anti-HBs) - Detects antibody produced in response to HBV surface antigen. Used to detect previous exposure to HBV; it can also develop from successful vaccination so it is used to determine the need for vaccination (if anti-HBs is absent) or to determine if a person has recovered from an infection and is immune (cannot get the infection again).

Clinical Significance

HBeAb appears in the early convalescence of HBV infection. With carrier state and chronic hepatitis, HBeAb may not develop.

Alternative Name(s)

HBe Antibody,Anti-Hepatitis Be


Hepatitis B e-antigen (HBeAG) - Detects protein produced and released into the blood. Often used as a marker of ability to spread the virus to other people (infectivity); it may also be used to monitor the effectiveness of treatment. However, there are some types (strains) of HBV that do not make e-antigen; these are especially common in the Middle East and Asia. In areas where these strains of HBV are common, testing for HBeAg is not very useful to determine whether the virus can be spread to others.

 

 

Clinical Significance

HBeAg indicates active HBV replication. Infectivity is evaluated based on HBeAg and HBsAg. When HBeAg persists much longer than 10 weeks, the patient is likely to develop chronic hepatitis and be a carrier.

Alternative Name(s)

HBe Antigen


Hepatitis C AB with reflex to HCV RNA, QN, PCR

IMPORTANT - THIS IS A REFLEX TEST AND AN ADDITIONAL CHARGE OF $129 WILL BE APPLIED IF THE Hepatitis C Antibody is reactive.

If Hepatitis C Antibody is reactive, then Hepatitis C Viral RNA, Quantitative, Real-Time PCR will be performed at an additional charge of $129.00

For the detection of active HCV infection in HCV antibody positive individuals.

Clinical Significance

Hepatitis C Virus (HCV) is a major cause of hepatitis. The clinical symptoms of an HCV infection are variable. Infection with HCV results in a chronic infection in 50 to 80% of cases. The "window" between HCV acquisition and seroreactivity is highly variable; up to six months.

 


Hepatitis C Antibody with Reflex to HCV, RNA, Quantitative, Real-Time PCR 

IMPORTANT: If Hepatitis C Antibody is reactive, then the Hepatitis C Viral RNA, Quantitative, Real-Time PCR test will be performed at an additional charge of $129.00.

Limitations

Results obtained from immunosuppressed patients should be interpreted with caution. Patients receiving mouse antibody therapy may produce false-negative results.

Reference Range(s)

Hepatitis C Antibody  Non-Reactive

Signal to Cut-off<1.00

Clinical Significance

Hepatitis C Virus (HCV) is a major cause of hepatitis. The clinical symptoms of an HCV infection are variable. Infection with HCV results in a chronic infection in 50 to 80% of cases. The "window" between HCV acquisition and seroreactivity is highly variable; up to six months.

Alternative Name(s)

HCV with Reflex,HCV Antibody,Anti HCV

 



According to the CDC, about 4.4 million Americans are currently infected with Hepatitis B or C. Many of them are not even aware that they have the infection. These numbers are seriously high, so it's important to educate yourself about hepatitis in all its forms and how to take preventative measures against infection.

Thankfully, science has been able to identify the disease and develop effective hepatitis testing methods. As a result, it is easier than ever to get tested for all forms of hepatitis and get on the fast track to treatment and recovery.

To learn more about hepatitis and how you can get tested, read this guide.

What Is Hepatitis A, B & C?

Hepatitis is a disease that causes inflammation of the liver. This condition can come from either an autoimmune disorder or a viral infection. Hepatitis comes in many forms and comes from many different causes, so staying vigilant with your health is key.

Hepatitis can be dangerous because the liver performs many vital functions for our body. It helps filter our blood to remove toxins and it produces bile for proper digestion. Without our liver, we could not:

  • Digest what we consume
  • Filter toxins from our body
  • Store and break down essential vitamins, minerals, proteins, fats, and carbohydrates
  • Synthesize clotting factors or essential blood proteins

Your liver is not an organ you can sacrifice when it goes bad. Unlike a gallbladder, we cannot live without a functioning liver. Hepatitis, therefore, can be life-threatening.

Types of Hepatitis

There are several different forms of hepatitis, including A, B, C, D, and E. The most common forms are A, B, and C. Each form causes hepatitis but comes from a different virus.

Hepatitis A and E are usually acute, short-term conditions. Hepatitis B, C, and D typically become long-term, chronic illnesses.

Hepatitis A comes from consuming food or water that HAV-infected feces has contaminated. This usually occurs when the feces has come from someone infected with HAV. Hepatitis E is similar yet much rarer in the US because it typically occurs in countries with poor sanitation.

Hepatitis B comes from contact with HBV-infected fluids such as vaginal fluid, semen, or blood from someone with hepatitis B. Hepatitis D is very rare as it can only occur in conjunction with hepatitis B—it depends on HBV to survive.

Hepatitis C is carried by HCV, and it is similar to B as it is also transmitted through contact with infected fluids.

If you are living in the United States, you should mainly worry about hepatitis A, B, and C.

Causes and Risk Factors for Hepatitis A, B, and C.

When it comes to risk factors for hepatitis, doctors will warn against certain lifestyle choices. Because the hepatitis-causing viruses transfer through bodily fluids and waste, coming in close contact with or sharing certain devices with infected people puts you at risk.

For example, you could contract HBV or HCV if you have had a sexual interaction with an infected person. Therefore, if you have multiple or new sex partners, you are at higher risk of infection.

HBV and HCV are also commonly transferred through unsanitary drug injection practices. Sharing a needle with an infected person could put you at risk of infection. Sharing razors, too, could cause infection if razors have come in contact with infected blood.

The risks of developing hepatitis generally have nothing to do with whether you are biologically more susceptible to it. Both men and women are equally vulnerable, and no pre-existing conditions cause higher rates of infection.

Certain conditions that physicians call hepatitis, however, can link to your biological makeup. An autoimmune disorder can inflame your liver. This occurs when your immune system believes your liver is a foreign invader and attacks it.

A form of hepatitis, also called alcoholic hepatitis, can come from excessive alcohol and drug use. Introducing your liver to excessive toxins over a period of time can lead to serious liver damage and inflammation.

Signs and Symptoms of Hepatitis A, B, and C?

Hepatitis A is an acute, short-term illness. You will most likely experience signs and symptoms right away, such as sudden nausea and vomiting, fatigue, and pain around the liver. Get tested right away if you also experience the signs below.

Hepatitis B and C are long-term illnesses that may not show signs right away. Your symptoms will worsen over time. You could experience:

  • Flu-like symptoms
  • Fatigue
  • Pale stool
  • Dark urine
  • Loss of appetite
  • Unexplained weight loss
  • Pain in the abdomen
  • Signs of jaundice, like yellow eyes and skin

These signs are all related to liver dysfunction and might not necessarily be caused by hepatitis. That's why it is so important to get tested immediately to determine the cause.

How Is Hepatitis A, B, and C Diagnosed?

If you go to a doctor for a hepatitis B screening or a hepatitis C screening, they will first ask about your medical history and lifestyle. Then, they will perform a physical hepatitis screening exam.

They will look for risk factors in your lifestyle and check for yellowed eyes and skin or discomfort around the liver. Whether the preliminary exam shows signs or not, a doctor will likely run further tests to determine your condition.

You can get a hepatitis B test and a hepatitis C test if your doctor feels your condition is long-term rather than acute. These tests can find antibodies in your blood that indicate you are fighting off the infection. 

Hepatitis Testing for A, B, and C

Physicians can perform a number and combination of tests to diagnose your condition. Blood tests and liver function tests can determine whether your health condition is caused by hepatitis and further diagnose you with a type. Ultrasounds and liver biopsies are also options, but more invasive and generally unnecessary for diagnosis.

Even without the hassle of a doctor's appointment and extra exams, you can get results immediately with a blood test from Ulta Lab Tests. If you are concerned at all that you have contracted hepatitis, you can buy a highly accurate and reliable blood test to be performed and analyzed in private. You can take control of your health and move forward with an informed decision.

Take Control of Your Health Today

Order your hepatitis lab tests today with Ulta Lab Tests. Here are a few great things to love about our service:

- You'll get secure and confidential results
- You don't need health insurance
- You don't need a physician's referral
- You'll get affordable pricing
- We offer a 100% satisfaction guarantee
- Results within 24-48 hours for most tests

Take control of your health today with Ulta Lab Tests.