Measles, Mumps, Rubella, Varicella

MMR/VZV titers are blood tests that measure IgG antibodies to measles, mumps, rubella, and varicella-zoster (chickenpox). Programs often require proof of immunity for school, healthcare employment, travel, or clinical rotations. Titers can also confirm a post-vaccination response or help guide planning for pregnancy when rubella or varicella immunity is uncertain.

A proactive approach is simple: order the exact titers your form requests, draw blood ≥3–4 weeks after vaccination (if you just completed a series or booster), and compare results with the assay’s reference cutoffs. These tests verify immunity status and support documentation; they do not diagnose current illness and do not replace your clinician’s advice about vaccination or follow-up.

Signs, Symptoms & Related Situations

  • Documentation & compliance

    • School/college, healthcare onboarding, immigration/travel, volunteer placements

    • Lost or uncertain vaccine records; need proof of measles, mumps, rubella, varicella immunity

  • Care planning

    • Pregnancy planning (rubella/varicella immunity)

    • Post-vaccination checks after boosters or series completion

  • Outbreak or exposure contexts

    • Public-health requests for measles or varicella immunity evidence

  • Acute illness (diagnostic tests differ)

    • Measles: fever, cough, coryza, conjunctivitis, rash

    • Mumps: parotid swelling, jaw pain

    • Rubella: mild fever, rash, joint aches

    • Varicella: diffuse, itchy vesicular rash
      (Acute evaluation uses targeted testing; titers for immunity are not for diagnosing today’s symptoms.)

  • Seek urgent care now: breathing trouble, confusion, dehydration, or rapidly worsening illness.

Why These Tests Matter

What testing can do

  • Provide proof of immunity with disease-specific IgG titers

  • Confirm serologic response after vaccination (e.g., rubella/varicella IgG)

  • Establish a baseline for program forms or preconception care

What testing cannot do

  • Diagnose current infection or determine contagiousness

  • Guarantee lifetime protection—antibodies can wane, and cutoffs vary by assay

  • Replace recommended vaccination/boosters or your clinician’s guidance

What These Tests Measure (at a glance)

  • Measles (Rubeola) IgG: evidence of immunity; often required for schools and healthcare workers.

  • Mumps IgG: documentation for employment/education settings.

  • Rubella IgG: crucial for pregnancy planning—immunity reduces risk of congenital rubella syndrome.

  • Varicella-Zoster (VZV) IgG: shows immunity from prior infection or vaccination.

  • IgM (acute infection work-ups only): used selectively for current illness under clinician guidance; not for immunity documentation.

  • Result formats: qualitative (positive/negative) or quantitative units with assay-specific cutoffs. Methods are not interchangeable—trend with the same assay when possible.

Quick Build Guide

Documentation goal Start with Add if needed
Healthcare/clinical placement Measles IgG • Mumps IgG • Rubella IgG • Varicella IgG Program-specific forms or additional vaccines
School/immigration package MMR IgG panel + Varicella IgG Hepatitis B surface Ab (if required)
Pregnancy planning Rubella IgG • Varicella IgG Repeat per clinician plan if nonreactive after vaccination
Post-vaccine response Target-specific IgG (draw ≥3–4 weeks after dose/series) Retest after booster if nonreactive (clinician-directed)
Outbreak verification Disease-specific IgG Follow public-health instructions

How the Testing Process Works

  1. Select the exact titers listed on your form (measles, mumps, rubella, varicella).

  2. Time your draw: if you were recently vaccinated, test ≥3–4 weeks after the last dose. No fasting needed.

  3. Provide your blood sample at a nearby patient service center; results post securely in your account.

  4. Compare and submit: review your report’s cutoffs and any quantitative values; submit documentation as requested.

  5. Plan follow-up: if nonreactive or equivocal, your clinician may recommend revaccination and a repeat titer.

Interpreting Results (General Guidance)

  • Positive/Reactive IgG: consistent with immunity or past exposure; many programs accept this as proof when the method and units are documented.

  • Negative/Nonreactive IgG: may indicate no immunityearly testing, or waning antibodies—consider vaccination and retesting per clinician advice.

  • Equivocal/Borderline: retesting or revaccination is often advised, depending on program rules.

  • IgM testing: used for suspected acute infection only; it is not part of routine immunity documentation.

Choosing Panels vs. Individual Tests

  • Program bundle: order the MMR IgG panel plus Varicella IgG to mirror most checklists.

  • Single-purpose check: choose just the one antibody you need (e.g., Rubella IgG for preconception).

  • Add-ons: include other titers only if your school/employer requests them.

FAQs

Do I need to fast?
No. These are standard blood tests without fasting.

How soon after vaccination should I draw titers?
Wait at least 3–4 weeks after the final dose for the clearest result.

Will a positive IgG always be accepted?
Most programs accept positive IgG with method/units, but requirements vary—follow your form’s instructions.

My rubella or varicella IgG is negative—what next?
Your clinician may advise vaccination (if appropriate) and a repeat titer.

Can titers diagnose measles or mumps right now?
No. Acute illness uses targeted diagnostics and public-health protocols.

Do I need titers if I have vaccine records?
Some programs accept records alone; others require titers. Check your checklist.

Will prior infection always make IgG positive?
Not always—antibodies can wane. Your clinician can advise on boosting and retesting.

Related Categories & Key Tests

  • Infectious Disease Tests Hub

  • Immunity & Titer Tests • Titer Tests • COVID-19 Antibody Tests • Employment & Deployment Testing • Pregnancy & Preconception

  • Key Tests: Measles (Rubeola) IgG • Mumps IgG • Rubella IgG • Varicella-Zoster IgG • (Clinician-directed acute testing: disease-specific IgM or PCR when needed)

References

  • Centers for Disease Control and Prevention — Measles, Mumps, Rubella, and Varicella immunity and vaccination guidance.
  • Advisory Committee on Immunization Practices (ACIP) — Evidence of immunity and post-vaccination serology considerations.
  • American College of Obstetricians and Gynecologists — Preconception and prenatal rubella/varicella immunity assessment.
  • World Health Organization — Serology standards and vaccine program guidance.
  • Clinical and Laboratory Standards Institute — Best practices for serology assay interpretation.

Available Tests & Panels

Your MMR/VZV Titers menu is pre-populated in the Ulta Lab Tests system. Use filters to select Measles IgG, Mumps IgG, Rubella IgG, and Varicella IgG as your program requires. If you recently received a vaccine, draw ≥3–4 weeksafter the dose for accurate results. Review your report with your clinician before submitting documentation or planning next steps.

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The MMR Titer Test is a quantitative blood test that measures antibody levels to measles, mumps, and rubella. Results provide exact antibody values to confirm prior infection or response to vaccination. Low levels suggest lack of protection, while higher levels indicate adequate response. Doctors order this test for school, employment, or travel requirements and to guide revaccination decisions, ensuring accurate evaluation of immune status against these viral diseases.

Also Known As: MMR Immunity Test, Measles Mumps Rubella Titer, Measles Mumps Rubella IgG Antibodies

The Measles, Mumps, Rubella (MMR) Immunity Profile is a quantitative blood test that measures antibody levels to measles, mumps, and rubella. Results confirm prior infection or vaccine response and show if antibody levels are protective. Doctors order this test for school, employment, or travel requirements, to evaluate vaccine effectiveness, and to guide revaccination decisions. It provides reliable assessment of immune protection against all three viral diseases.

Also Known As: MMR Titer Test

The Measles IgG IgM Antibodies Test measures immune response to the measles virus by detecting IgM for recent or acute infection and IgG for past exposure or vaccine immunity. This test helps confirm suspected measles cases in patients with fever, rash, cough, or conjunctivitis, and evaluates immunity in those with uncertain vaccination history, supporting diagnosis, outbreak control, and public health monitoring.

Also Known As: Rubeola Test, Measles Virus Test, Measles Titer test, Measles Infection Test

The Measles IgG Antibody Test measures IgG antibodies to determine immunity from past infection or vaccination. A positive result indicates protective immunity, while a negative result suggests susceptibility to measles. Doctors use this blood test to confirm immune status, evaluate vaccination records, or meet school, travel, or employment requirements. It provides valuable insight into measles protection and public health safety.

Blood
Blood Draw
Also Known As: Rubeola Test, Measles Virus Test, Measles Titer Test

The Measles IgM Antibody Test detects IgM antibodies specific to the measles virus, providing evidence of recent or acute infection. IgM antibodies typically appear shortly after exposure and indicate an active immune response. This test is used to confirm measles in symptomatic patients, support outbreak investigations, and distinguish between current infection and prior immunity, aiding timely clinical and public health decisions.

Blood
Blood Draw
Also Known As: Rubeola Test, Measles Virus Test, Measles Infection Test

The Measles Titer Test measures IgG antibody levels to determine immunity from prior measles infection or vaccination. A positive result indicates protective immunity, while a negative result suggests susceptibility. Doctors order this test to confirm immune status for school, healthcare, travel, or employment requirements. It is also used to verify vaccination response, ensuring individuals are protected against measles and reducing outbreak risk.

Blood
Blood Draw
Also Known As: Rubeola Test, Measles Virus Test, Measles IgG Antibody Test

The Mumps Virus Titer Test measures IgG antibodies to determine immunity from prior infection or vaccination. A positive result indicates protective immunity, while a negative result suggests susceptibility to mumps. Doctors use this blood test to confirm immune status, check vaccine response, or meet school, travel, or employment requirements. It provides valuable information for individual protection and public health safety.

Blood
Blood Draw
Also Known As: Mumps Virus IgG Antibody Test, Mumps Virus Test

The Rubella IgG IgM Antibodies Test measures antibodies to the rubella virus, helping evaluate immunity or recent infection. IgM indicates an active or recent infection, while IgG confirms past infection or vaccination. Doctors use this test to assess immune status in women of childbearing age, screen during pregnancy, or confirm suspected rubella exposure, as infection can cause serious complications for unborn babies.

Also Known As: Rubella Titer, Rubella Antibodies Test, German Measles Test

The Rubella IgM Antibody Test measures immune response to the rubella virus by identifying IgM antibodies produced soon after exposure. Detection of rubella IgM helps diagnose recent infection, assess rash-related illness, and monitor risk in pregnancy where congenital rubella syndrome may occur. This test provides valuable insight into acute infection, immunity status, and systemic health.

Blood
Blood Draw
Also Known As: German Measles test, 3 Day Measles Test, Three Day Measles Test, Rubella Infection Test

The Rubella Titer Test measures IgG antibodies to determine immunity to rubella (German measles). A positive result indicates protection from prior infection or vaccination, while a negative result suggests susceptibility. Doctors order this test for women planning pregnancy, healthcare workers, students, or travelers. It helps confirm immune status, guide vaccination needs, and protect against congenital rubella syndrome and outbreak risks.

Blood
Blood Draw
Also Known As: Rubella IgG Antibody Test, Rubella Immune Status Test, German Measles Test, 3 Day Measles Test, Three Day Measles Test

The Total T and B Cells Test measures levels of T lymphocytes and B lymphocytes, key white blood cells essential for immune defense. Abnormal counts may indicate immune deficiencies, autoimmune disorders, infections, or blood cancers. Doctors use this test to evaluate immune system function, diagnose underlying conditions, and monitor treatment. It is often ordered with other immune panels to provide a comprehensive view of adaptive immunity.


The Varicella Zoster Virus IgG IgM Antibodies Panel is used to assess exposure to the varicella-zoster virus, which causes both chickenpox and shingles. By evaluating the presence and levels of specific antibodies, this panel aids in diagnosing current infections, determining immunity, and guiding vaccination decisions.
Blood
Blood Draw
Panel Contains Test: Varicella Zoster Virus Antibodies Test

The Varicella Titer Test is a blood test that measures antibodies to the varicella-zoster virus (VZV), which causes chickenpox and shingles. A positive result indicates past infection, while a negative suggests no exposure. This test is not considered reliable for confirming immunity from vaccination. Doctors use it to evaluate history of natural infection, meet school or work requirements, and provide documentation of varicella exposure status.

Blood
Blood Draw
Also Known As: Varicella Zoster Virus IgG Antibody Test, Chicken Pox Titer Test, Shingles Titer Test

The Varicella IgM Antibody Test measures IgM antibodies produced in response to varicella-zoster virus, helping identify current or recent chickenpox infection. It aids in differentiating acute illness from prior exposure or immunity. This test supports evaluation of symptoms such as rash, fever, or fatigue, and provides valuable information about immune activity and viral health risks.

Blood
Blood Draw
Also Known As: Varicella Zoster Virus IgM Antibody Test, Chick Pox IgM Antibody Test

Before the MMR vaccine became available, three to four million people contracted measles every year in the United States. The CDC estimates that 400 to 500 people died among reported cases, 48,000 were hospitalized, and 1,000 developed brain swelling each year.

While the United States declared measles eliminated from the country in 2000, there are still outbreaks from time to time. In addition, if vaccine coverage levels were to drop, measles could once again become a constant presence. 

If you think you've been exposed to someone with measles, you'll benefit from undergoing an MMR titer test to understand if you have immunity.

Defining Measles, Mumps, Rubella (MMR)

One of the first written accounts of measles is from the ninth century by a Persian doctor. However, in 1757, Francis Home, a Scottish doctor, determined that an infection causes measles in the blood. 

In 1912, the United States declared measles a nationally notifiable disease, requiring healthcare providers to report diagnosed cases. In that first decade of reporting, approximately 6,000 measles-related deaths were reported each year. 

Mumps, also called parotitis, affects the salivary glands. While some people may experience no symptoms, others could have painfully swollen glands, headache, fever, fatigue, and appetite loss. Patients typically recover in about two weeks. 

Rubella, also known as German measles, is best recognized by its distinctive red rash. Rubella is highly contagious, and it spreads through close contact or the air. Most illnesses are mild, but the condition can quickly become severe. 

Risk Factors and Causes of Measles, Mumps, Rubella 

Because measles, mumps, and rubella have generally been eliminated from the United States, there are only a few risk factors. Those factors include the following: 

  • Not being vaccinated
  • Traveling internationally 
  • Having a vitamin A deficiency

If you think you might have contracted measles, mumps, or rubella, it's important to contact a healthcare provider as soon as possible. 

Signs and Symptoms of Measles, Mumps, and Rubella 

If someone has contracted measles, their symptoms will start to appear 7 to 21 days after exposure. It starts with a mild to moderate fever, runny nose, sore throat, red eyes, and a cough. 

Two to four days after symptoms present, tiny white spots will begin to appear inside the mouth. Three to five days after symptoms begin, a rash appears, typically on the face. The rash is raised and feels like sandpaper and spreads down the entire body. 

When the rash appears, a person's temperature can spike as high as 104 degrees Fahrenheit. Symptoms typically last seven to ten days. There is no specific treatment for this illness, but a diagnosis can be confirmed with an MMR blood titer test. 

Mumps can cause pain in the swollen salivary glands, pain while chewing, muscle aches, fever, headache, and fatigue. It's important to see a doctor, as mumps is highly contagious for about nine days after symptoms appear. 

If left untreated, mumps can cause inflammation in different parts of the body like the testicles, brain, spinal cord, and pancreas. 

Rubella presents differently in children and adults. For children with rubella, a red rash is typically the first sign. They may also experience a low-grade fever, headache, general discomfort, and a cough. 

In adults, rubella is typically a mild illness that involves a low-grade fever, sore throat, and rash. 

Diagnosing Measles, Mumps, and Rubella

Doctors are typically able to diagnose measles based on the distinct characteristics of the disease, like the rash and the white spots on the inside of the cheek. If necessary, a blood test could confirm measles. Physicians will also sometimes test with a throat swab or urine sample. 

With a confirmed diagnosis, a patient needs to understand what they need to do to improve their health and protect others. There is no specific treatment for a measles infection, but measures can be taken to protect others who may have been exposed to the virus. 

For example, a doctor could order a post-exposure vaccination or immune serum globulin. With either route, measles may be prevented or develop with milder symptoms. 

If you suspect you have mumps, your doctor will start by asking if you've been vaccinated against the illness and whether you know of potential exposure. Thye may recommend a blood test to check for evidence of the mumps virus.

A rubella rash can look like a number of other viral rashes. To confirm a diagnosis, your doctor will order laboratory tests. You may have a blood test or a virus culture. 

MMR Immunity and the MMR Titer Test 

Immunity for measles, mumps, and rubella is most easily achieved with a vaccine. The most common vaccine for measles is MMR, which protects against measles, mumps, and rubella. Research has shown that the vaccine is safe and is the most effective way to have MMR immunity. 

Common side effects associated with the vaccine include pain at the injection site, fever, mild rash, and swollen glands in the neck or cheek. 

If you're uncertain if you've been vaccinated, you'll benefit from an MMR titer blood test. The MMR antibody titer test checks for immunity to the three illnesses by measuring antibody levels to determine if your immune system can respond to an infection with one of the diseases. 

The MMR titer test can also be used, in some instances, as a way to diagnose measles, mumps, or rubella. This is because the presence of certain viral antibodies can be evidence of an infection. 

Frequently Asked Questions About MMR

Even with all of the information above, you may still have questions about measles, mumps, and rubella. Keep reading for answers to some of the most frequently asked questions. 

  • How do you know if you're protected against MMR?
    • The CDC considers a person protected against measles, mumps, and rubella if they received two doses of the MMR vaccine as a school-age child or adult, received one dose of the MMR vaccine if you are a preschool-age child, you were officially diagnosed with measles, mumps, or rubella at some point in your life, or you were born before 1957. 
  • What should you do if you think you've been exposed to someone with measles, mumps, or rubella? 
    • If you think you've been exposed to someone with measles, mumps, or rubella, call your healthcare provider to determine if you have a vaccination record on file and whether you need to start certain medications to reduce your risk of developing any of the three diseases.
  • What do you do if you test positive for measles, mumps, or rubella?  
    • If you test positive for measles, mumps, or rubella, you need to stay home for at least four days after you start to develop a rash, practice good hygiene, and disinfect frequently touched surfaces. 

For more information on MMR, consult your primary care physician. 

Learn More From Ulta Lab Tests 

If you're looking for fast results to an MMR titer test, Ulta Lab Tests can help. 

Ulta Lab Tests offers tests that are highly accurate and reliable. When you order testing from us, you'll have access to secure and confidential results. And, you won't need to worry about having a doctor's referral or health insurance. 

Order your MMR titer tests today, and your results will be provided to you securely and confidentially online in 24 to 48 hours for most tests.

Take control with Ulta Lab Tests today!