Adrenal Insufficiency and Addison Disease

The Aldosterone and Plasma Renin Activity Ratio Test measures levels of aldosterone and renin to assess adrenal and kidney function. An elevated ratio may indicate primary aldosteronism, a common cause of secondary hypertension. Doctors use this test to evaluate patients with high blood pressure, low potassium, or suspected adrenal disorders. Results help diagnose conditions like Conn’s syndrome, guide treatment, and reduce cardiovascular risks from uncontrolled hypertension.

The C-Reactive Protein (CRP) Test measures CRP levels in blood to detect inflammation in the body. Elevated CRP may indicate infections, autoimmune disorders, or chronic diseases such as arthritis, cardiovascular disease, or inflammatory bowel disease. Doctors use this test to assess acute illness, monitor treatment response, and evaluate risk for heart disease. The CRP test provides key insight into inflammation, immune health, and overall wellness.

The Comprehensive Metabolic Panel (CMP) Test measures 21 markers to assess metabolic health, liver and kidney function, and electrolyte balance. It includes glucose, calcium, sodium, potassium, chloride, CO2, albumin, globulin, A/G ratio, total protein, bilirubin, ALP, AST, ALT, BUN, creatinine, BUN/creatinine ratio, and eGFR. The CMP helps detect diabetes, liver or kidney disease, and supports routine screening and chronic condition monitoring.

The Cortisol Saliva 4 Samples Test measures cortisol levels at four points during the day to assess adrenal gland function and circadian rhythm. Abnormal patterns may indicate adrenal insufficiency, Addison’s disease, Cushing’s syndrome, or chronic stress. Because saliva reflects active hormone levels, this noninvasive test is ideal for evaluating diurnal cortisol changes, supporting diagnosis, and guiding treatment for endocrine and stress-related disorders.

The Cortisol AM Test measures morning cortisol levels in blood to evaluate adrenal gland function and stress response. Cortisol peaks in the morning, making this test critical for detecting adrenal insufficiency (Addison’s disease), Cushing’s syndrome, or other hormone imbalances. Doctors also use it to investigate fatigue, weight changes, or high blood pressure. This test provides important insight into endocrine health, metabolism, and long-term stress regulation.

The Cortisol PM Test measures afternoon cortisol levels to evaluate adrenal and pituitary function. Cortisol normally drops later in the day, so abnormal results may indicate Cushing’s syndrome, adrenal insufficiency (Addison’s disease), or hormone imbalance. Doctors order this test to investigate fatigue, obesity, high blood pressure, or irregular sleep patterns and to monitor adrenal disorders. It provides key insight into stress response and endocrine health.

The Cortisol Total Test measures cortisol levels in blood to assess adrenal gland and pituitary function. Cortisol regulates stress response, metabolism, and immune health. Abnormal results may indicate Cushing’s syndrome, Addison’s disease, or other hormone disorders. Doctors order this test to evaluate symptoms like fatigue, weight changes, weakness, or high blood pressure and to monitor treatment. It provides essential insight into hormone balance and endocrine health.

The DHEA Sulfate (DHEA-S) Test measures levels of DHEA-S, a hormone made by the adrenal glands, to evaluate adrenal function and hormone balance. It helps detect adrenal tumors, hyperplasia, or insufficiency and assess abnormal hair growth, infertility, or early/late puberty. Doctors also use it to investigate irregular menstrual cycles, monitor androgen disorders, and evaluate symptoms of hormone imbalance affecting reproductive and metabolic health.

The GGT Test measures gamma-glutamyl transferase, an enzyme found in the liver and bile ducts, to evaluate liver health. Elevated GGT may indicate liver disease, bile duct obstruction, alcohol use, or medication side effects. Doctors order this test to investigate symptoms like fatigue, jaundice, dark urine, or abdominal pain and to monitor liver damage. It is often performed with other liver tests to provide a complete picture of liver and bile duct function.

The Hemoglobin A1c (HbA1c) Test measures average blood glucose over 2–3 months by detecting sugar attached to hemoglobin in red blood cells. It is used to diagnose diabetes, identify prediabetes, and monitor long-term blood sugar control. Doctors rely on the HbA1c test to evaluate treatment effectiveness, guide adjustments, and assess risk for complications, making it essential for diabetes care and metabolic health screening.

The Homocysteine Test measures homocysteine levels in blood to assess risk for heart disease, stroke, and vascular problems. Elevated homocysteine may result from vitamin B6, B12, or folate deficiency and is linked to blood clots, cognitive decline, and osteoporosis. Doctors use this test to evaluate cardiovascular risk, monitor nutritional deficiencies, and guide treatment for metabolic or genetic conditions affecting homocysteine metabolism.

The Insulin Test measures insulin levels in blood to assess how the body regulates glucose and metabolism. It helps diagnose insulin resistance, hypoglycemia, type 2 diabetes, and metabolic syndrome. Doctors also use it to evaluate pancreatic function and monitor treatment effectiveness. Frequently ordered with glucose testing, the insulin test provides critical insight into endocrine health, blood sugar control, and risk for diabetes-related complications.

The Iron Micronutrient Test measures blood iron levels to evaluate nutritional status and detect deficiencies or excess. Iron is essential for hemoglobin production, oxygen transport, energy metabolism, and immune function. This test helps identify anemia, iron overload, absorption issues, or dietary imbalances, supporting diagnosis and management of overall health and vital body functions.

Patient must be 18 years of age or older.

The Iron Total Test measures iron levels in blood to evaluate nutritional status, red blood cell production, and overall metabolic health. Abnormal levels may indicate iron deficiency anemia, chronic blood loss, or poor absorption, while high levels may suggest hemochromatosis, liver disease, or iron overload. Doctors use this test to investigate fatigue, weakness, or pallor and to monitor treatment. Results provide key insight into anemia and iron balance.

The Mineral Micronutrients Test Panel measures minerals: Calcium, Chromium, Copper, Iron, Magnesium RBC, Manganese, Molybdenum, Selenium, and Zinc to assess nutritional balance and overall health. These minerals are essential for bone strength, metabolism, energy production, antioxidant defense, and immune function. The panel helps detect deficiencies, excesses, or absorption issues, guiding health management.

Patient must be 18 years of age or older.

The Lactate Dehydrogenase (LDH) Test measures LDH enzyme levels in blood to assess tissue damage and overall health. Elevated LDH may indicate conditions such as liver disease, heart attack, anemia, infections, or certain cancers, while low levels are uncommon. Doctors use this test to help diagnose disease, monitor treatment effectiveness, and track cell damage. It provides valuable insight into metabolic activity and organ function.

The Lipid Panel with Ratios Test measures seven key markers: total cholesterol, HDL, LDL, non-HDL cholesterol, triglycerides, Chol/HDL ratio, and LDL/HDL ratio. This advanced panel evaluates cardiovascular risk by assessing cholesterol balance and fat metabolism. Doctors use it to detect high cholesterol, atherosclerosis risk, and heart disease, and to monitor treatment. Often part of routine exams, it provides insight into long-term heart and metabolic health.

The Magnesium Serum Test measures magnesium levels in blood to evaluate electrolyte balance, nerve and muscle function, and overall metabolic health. Abnormal levels may indicate kidney disease, malnutrition, gastrointestinal disorders, or uncontrolled diabetes. Low magnesium can cause weakness, cramps, or irregular heartbeat, while high levels may signal kidney dysfunction. Doctors use this test to diagnose deficiencies, monitor therapy, or assess chronic health conditions.

The Phosphate (as Phosphorus) Test measures phosphorus levels in blood to evaluate bone strength, energy metabolism, and kidney health. Abnormal levels may indicate kidney disease, vitamin D imbalance, parathyroid disorders, or malnutrition. Doctors order this test to investigate fatigue, muscle weakness, or bone problems and to monitor conditions like chronic kidney disease. It provides key insight into metabolic, endocrine, and bone health.

The Sex Hormone Binding Globulin (SHBG) Test measures SHBG, a protein that binds testosterone and estrogen, to assess how much active hormone is available in the body. Abnormal levels may indicate PCOS, infertility, low testosterone, liver disease, or thyroid disorders. Doctors order this test to investigate symptoms like low libido, irregular periods, acne, or hair loss and to evaluate hormone balance, endocrine function, and metabolic health in men and women.

The Uric Acid Test measures uric acid levels in blood to assess kidney function and detect gout, a form of arthritis caused by uric acid buildup. High levels may also signal kidney disease, kidney stones, or metabolic disorders, while low levels can occur with liver disease. Doctors use this test to investigate joint pain, swelling, or frequent urination, and to monitor treatment for gout, kidney stones, or chemotherapy-related complications.

The QuestAssureD™ Vitamin D 25-Hydroxy Total Test measures Vitamin D2, Vitamin D3, and total 25-hydroxy vitamin D to assess overall vitamin D status. Adequate vitamin D supports bone strength, calcium absorption, immune health, and muscle function. Low levels may cause osteoporosis, weakness, or increased disease risk, while high levels can indicate toxicity. Doctors use this test to diagnose deficiency, monitor supplementation, and evaluate metabolic and endocrine health.