Glucose, Gestational Screen (50g), 140 Cutoff

The Glucose, Gestational Screen (50g), 140 Cutoff test contains 1 test with 1 biomarker.

Brief Description: The Gestational Glucose Screen (50g) 140 Cutoff Test is a preliminary test used to screen for gestational diabetes in pregnant women. During the test, the patient consumes a drink containing 50 grams of glucose, and one hour later, a blood sample is drawn to measure the glucose level. The "140 Cutoff" refers to the threshold level, in milligrams per deciliter (mg/dL), that is typically used to determine whether a more definitive test for gestational diabetes is necessary.

Collection Method: Blood Draw

Specimen Type: Plasma

Test Preparation: No preparation required

When and Why a Gestational Glucose Screen (50g) 140 Cutoff Test May Be Ordered

This test is typically ordered between the 24th and 28th weeks of pregnancy, though it can be done earlier if the woman is at high risk for diabetes. Reasons for ordering include:

  1. Routine Screening: As part of standard prenatal care for all pregnant women.
  2. Risk Factors: The presence of risk factors such as obesity, a family history of diabetes, previous gestational diabetes, or previously giving birth to a large baby.
  3. Age: Pregnant women over the age of 25 may have an increased risk of developing gestational diabetes.

What the Gestational Glucose Screen (50g) 140 Cutoff Test Checks For

The test measures how the body processes glucose after consumption. An elevated blood glucose level one hour after drinking the glucose solution may indicate that the body isn't processing glucose effectively, which can be a sign of gestational diabetes.

Other Lab Tests Ordered Alongside Gestational Glucose Screen (50g) 140 Cutoff Test

When a 140 Cutoff Gestational Glucose Screen is ordered, it's often part of a broader assessment of maternal and fetal health. Here are some tests commonly ordered alongside it:

  1. 3-Hour Oral Glucose Tolerance Test (OGTT):

    • Purpose: To confirm a diagnosis of gestational diabetes if the initial screening test is positive.
    • Why Is It Ordered: This test involves fasting overnight and then drinking a glucose solution with blood glucose measurements taken at fasting, 1 hour, 2 hours, and 3 hours later.
  2. Hemoglobin A1c (HbA1c):

    • Purpose: To measure the average blood glucose levels over the past two to three months.
    • Why Is It Ordered: Although not routinely used for diagnosing GDM, it can provide additional information about glucose control in pregnancy, particularly for women at high risk or with pre-existing diabetes.
  3. Complete Blood Count (CBC):

    • Purpose: To evaluate overall blood health, including red blood cells, white blood cells, and platelets.
    • Why Is It Ordered: To identify conditions like anemia, common in pregnancy, which can impact maternal and fetal health.
  4. Urinalysis:

    • Purpose: To test for the presence of glucose, protein, and other substances in the urine.
    • Why Is It Ordered: To screen for urinary tract infections and check for proteinuria, which can be a sign of preeclampsia, especially important in pregnancies complicated by diabetes.
  5. Thyroid Function Tests:

    • Purpose: To assess thyroid gland function.
    • Why Is It Ordered: Pregnancy can affect thyroid function, and thyroid disorders can impact pregnancy outcomes.
  6. Lipid Profile:

    • Purpose: To measure levels of cholesterol and triglycerides.
    • Why Is It Ordered: While not routinely assessed in all pregnant women, lipid levels can be influenced by gestational diabetes and may be relevant in the management of women with pre-existing diabetes or other risk factors.

These tests, when ordered alongside a 140 Cutoff Gestational Glucose Screen, provide a comprehensive evaluation of maternal and fetal health during pregnancy, particularly in assessing and managing the risk of gestational diabetes. The specific combination of tests will depend on the individual’s health status, pregnancy history, and risk factors for gestational diabetes.

Conditions or Diseases Requiring a Gestational Glucose Screen (50g) 140 Cutoff Test

The primary condition this test screens for is:

  • Gestational Diabetes Mellitus (GDM): A form of diabetes that occurs during pregnancy. It can increase the risk of complications for both the mother and baby if not managed properly.

Usage of Results by Health Care Providers

Healthcare providers interpret the results as follows:

  • Below 140 mg/dL: The result is considered normal, suggesting a lower risk of gestational diabetes.
  • 140 mg/dL or Higher: The result suggests a potential risk of gestational diabetes, warranting further testing with the 3-Hour GTT.

Based on the outcome, healthcare providers can recommend appropriate dietary changes, monitoring, or treatment interventions to manage and reduce the risks associated with gestational diabetes.

In summary, the Gestational Glucose Screen (50g) 140 Cutoff Test is a crucial tool in prenatal care, ensuring the health and well-being of both the expectant mother and the baby. Proper management of gestational diabetes, if present, can prevent complications and promote a healthier pregnancy outcome.

Most Common Questions About the Glucose, Gestational Screen (50g), 140 Cutoff test:

Purpose and Clinical Indications

What is the primary purpose of the Gestational Glucose Screen (50g) 140 Cutoff test?

The Gestational Glucose Screen (50g) 140 Cutoff test is primarily used to screen pregnant women for gestational diabetes mellitus (GDM). GDM is a condition in which a woman without diabetes develops high blood sugar levels during pregnancy. The test helps identify those at increased risk of having GDM.

Interpretation of Results

How are the results of the Gestational Glucose Screen (50g) 140 Cutoff test interpreted?

If a pregnant woman's blood sugar level is below the 140 mg/dL cutoff after the 50g glucose challenge, she is considered to have passed the screening, suggesting a lower risk for GDM. If her blood sugar level is 140 mg/dL or higher, she is considered to have failed the screening and will typically be advised to undergo a more definitive glucose tolerance test to diagnose or rule out GDM.

Why is the 140 mg/dL cutoff used in the Gestational Glucose Screen (50g) 140 Cutoff test?

The 140 mg/dL cutoff is a value that has been found to identify approximately 80% of women with GDM. Using this cutoff balances the need to detect as many cases of GDM as possible against the desire to reduce the number of women who have to undergo the more time-consuming and demanding glucose tolerance test.

Clinical Insights

What happens if a pregnant woman fails the Gestational Glucose Screen (50g) 140 Cutoff test?

If a woman fails the Gestational Glucose Screen (50g) 140 Cutoff test, it doesn't mean she definitely has gestational diabetes. It means she is at a higher risk and should undergo a more comprehensive glucose tolerance test (often the 3-hour glucose tolerance test) to confirm or rule out the diagnosis of GDM.

Why is it essential to screen for and diagnose gestational diabetes during pregnancy?

Screening for and diagnosing gestational diabetes is crucial because elevated blood sugar levels during pregnancy can lead to complications for both the mother and the baby. These complications can include an increased risk of preeclampsia for the mother and an increased risk of macrosomia (large birth weight) for the baby. Diagnosing and managing GDM can help reduce these risks.

How frequently is the Gestational Glucose Screen (50g) 140 Cutoff test recommended during pregnancy?

The Gestational Glucose Screen (50g) 140 Cutoff test is typically recommended between the 24th and 28th weeks of pregnancy. However, for women at high risk for developing gestational diabetes (e.g., those with a history of GDM or with certain risk factors), screening may be advised earlier in the pregnancy.

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Glucose Gestational Screen 50g 140 Cutoff

Glucose, Gestational

A blood glucose test measures the amount of a sugar called glucose in a sample of your blood. Glucose is a major source of energy for most cells of the body, including those in the brain. The hormones insulin and glucagon help control blood glucose levels.
*Process times are an estimate and are not guaranteed. The lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

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