Prenatal Health

Prenatal health tests provide a clear picture of you and your baby’s well-being from early pregnancy through delivery. These labs check your blood type and antibodiesblood countiron statusinfections and immunitythyroid functionglucose for gestational diabetes, urine protein, and, when needed, bile acids for itching.

A proactive plan starts with a first-prenatal baseline (type & screen, CBC, infections, immunity, urine culture), then adds glucose screening at 24–28 weeks, and third-trimester assessments based on your risks. Targeted tests—such as thyroidiron studiesSTI screenshemoglobinopathy and genetic carrier tests, or bile acids—are added as your history or symptoms indicate. Labs support screening, diagnosis, and monitoring, but they do not replace prenatal visits, ultrasound, fetal testing, or emergency care.

Signs, Symptoms & Related Situations

  • Routine prenatal needs: establishing blood type/Rh, screening for anemia and infections, confirming immunity (rubella/varicella)

  • Metabolic & thyroid clues: prior diabetes/prediabetes, weight change, heat/cold intolerance, palpitations, fatigue

  • Urinary & blood pressure: burning urination, swelling, headaches—evaluate for UTI or hypertensive disorders

  • Skin & liver: intense itching on palms/soles (ask about bile acids for cholestasis)

  • Risk contexts: prior miscarriage, stillbirth, preeclampsia, preterm birth, IVF/ART, multiple gestation, hemoglobinopathy risk by ancestry/family history

  • Seek urgent care now: heavy bleeding, severe abdominal pain, decreased fetal movement, severe headache/vision changes, chest pain, shortness of breath, or signs of preterm labor

Symptoms and risks should be reviewed by your prenatal clinician.

Why These Tests Matter

What testing can do

  • Confirm maternal blood health (anemia/platelets) and Rh/antibody status for delivery planning

  • Identify treatable infections and confirm immunity to key illnesses

  • Detect gestational diabetes and monitor whole-body health (kidney, liver, electrolytes)

  • Support risk assessment for preeclampsia, cholestasis, thyroid disease, and hemoglobinopathies

What testing cannot do

  • Replace ultrasound, fetal monitoring, or labor and delivery decisions

  • Diagnose structural issues (tubal, uterine, placental) or predict birth timing

  • Provide treatment or dosing advice—interpret results with your obstetric clinician

What These Tests Measure (at a glance)

  • Blood type & Rh(D) with antibody screen: informs Rh management and transfusion planning.

  • CBC (Complete Blood Count): checks for anemia and platelet issues (preeclampsia/HELLP context).

  • Iron studies: ferritin, iron, TIBC, transferrin saturation to clarify iron-deficiency vs other anemia.

  • Infection screens (initial ± risk-based repeat): HIV 4th-generationsyphilis (RPR/treponemal), hepatitis B surface antigenhepatitis C antibodyurine culture.

  • Immunity titers: rubella IgGvaricella IgG (planning and exposure counseling).

  • STI NAATs: chlamydia/gonorrhea based on risk or local policy.

  • Glucose testing: clinician-directed gestational diabetes screening (24–28 weeks); A1c may provide early context but does not replace OGTT.

  • Chemistry/organ function: CMP (electrolytes, creatinine/eGFR, liver enzymes).

  • Thyroid: TSH ± Free T4 when you have thyroid history/symptoms or clinician request.

  • Urine protein & protein/creatinine ratio: evaluation for hypertensive disorders.

  • Bile acids (total ± fractionated): evaluation for intrahepatic cholestasis of pregnancy when itching persists.

  • Hemoglobinopathy & carrier screening (when indicated): hemoglobin electrophoresisCFTRSMA, and other ethnic/family-history–based tests.

Note: Group B Streptococcus (GBS) screening at 36–37 weeks is a swab, not a blood test, performed by your clinician.

Quick Build Guide

Goal / Scenario Start with Add if needed
First prenatal baseline Type & Screen • CBC • HIV • Syphilis • HBsAg • HCV Ab • Rubella IgG • Varicella IgG • Urine culture STI NAATs • A1c (context) • CMP
24–28 week glucose screen Clinician-directed GDM screen CMP • A1c (context)
Anemia suspected or low Hb/Hct CBC Ferritin • Iron/TIBC • B12 • Folate
Thyroid symptoms or known disease TSH Free T4
Preeclampsia work-up Platelets • Creatinine • AST/ALT • Urine protein/Cr LDH • Uric acid
Itching of palms/soles Total bile acids AST/ALT • Bilirubin
Hemoglobinopathy/family history Hemoglobin electrophoresis Genetic carrier tests (CFTR, SMA) per clinician

How the Testing Process Works

  1. Schedule by stage: complete baseline labs early in pregnancy; add 24–28 week glucose screening and third-trimester assessments as advised.

  2. Prepare correctly: most labs do not require fasting; follow instructions if a glucose test is scheduled. List all medicines and supplements (biotin can affect certain assays).

  3. Provide samples: standard blood draw plus a urine sample when requested.

  4. View secure results: most post within a few days.

  5. Plan next steps: your clinician integrates labs with blood pressure, ultrasound, fetal movement checks/NSTs, and your birth plan.

Interpreting Results (General Guidance)

  • Low hemoglobin/hematocrit with low ferritin → consistent with iron deficiency; confirm with your clinician.

  • Positive antibody screen → requires obstetric review for fetal/newborn planning.

  • Abnormal glucose screening → needs follow-up testing and a care plan.

  • Elevated AST/ALT, creatinine, or urine protein/Cr → evaluate urgently for preeclampsia/HELLP.

  • Elevated bile acids → supports cholestasis; management is clinician-directed.

  • Positive infection screen → prompts confirmatory testing and delivery planning considerations.
    Interpret results with your prenatal clinician; patterns and timing matter more than a single value.

Choosing Panels vs. Individual Tests

  • Core prenatal panel: Type & Screen • CBC • HIV • Syphilis • HBsAg • HCV Ab • Rubella IgG • Varicella IgG • Urine culture

  • Metabolic & thyroid add-ons: GDM screen (per clinician) • A1c (context) • CMP • TSH ± Free T4

  • Hypertension/preeclampsia panel: Platelets • Creatinine • AST/ALT • Urine protein/Cr (± LDH • Uric acid)

  • Anemia panel: Ferritin • Iron/TIBC • B12 • Folate

  • Cholestasis panel: Bile acids (± AST/ALT • Bilirubin)

  • Carrier & hemoglobinopathy: Hemoglobin electrophoresis • CFTR • SMA (clinician-directed)
    Choose bundled panels for efficiency; add targeted tests to answer specific questions.

FAQs

Do I need to fast for prenatal labs?
Usually no. Follow instructions if a glucose test is scheduled.

What is the antibody screen and why is it important?
It checks for antibodies that can affect the baby’s red cells and guides delivery planning.

Does A1c diagnose gestational diabetes?
No. A1c helps with context; glucose tolerance testing determines GDM.

Are all infection tests repeated later?
Some may be re-screened in the third trimester based on risk and local policy.

What if I’m Rh-negative?
Your clinician uses type & screen results to guide Rh management during pregnancy and at delivery.

Is GBS testing a blood test?
No—GBS is a vaginal/rectal swab around 36–37 weeks.

Do genetic carrier tests replace NIPT?
No. Carrier tests assess parental risk of passing certain conditions; NIPT screens fetal DNA for chromosomal conditions. Your clinician advises which are appropriate.

Related Categories & Key Tests

  • Pregnancy & Fertility Tests Hub

  • First Trimester Tests • Second Trimester Tests • Pregnancy Third Trimester Tests • Gestational Diabetes • Thyroid in Pregnancy • Anemia & Blood Count • Infection STD Tests

  • Key Tests: Blood Type & Rh • Antibody Screen • CBC • Ferritin • Iron/TIBC • B12 • Folate • HIV 4th-gen • Syphilis (RPR/treponemal) • Hepatitis B Surface Antigen • Hepatitis C Antibody • Rubella IgG • Varicella IgG • Urine Culture • TSH ± Free T4 • CMP • Creatinine/eGFR • AST • ALT • Platelets • Urine Protein/Creatinine Ratio • Bile Acids • Hemoglobin Electrophoresis • STI NAATs • A1c (context) • Glucose Screening (clinician-directed)

References

  • American College of Obstetricians and Gynecologists (ACOG) — Prenatal care and screening guidance.
  • Society for Maternal-Fetal Medicine (SMFM) — Hypertensive disorders, cholestasis, and gestational diabetes resources.
  • Centers for Disease Control and Prevention (CDC) — STI screening, perinatal hepatitis and HIV recommendations.
  • American Diabetes Association — Standards of Medical Care in Diabetes: Pregnancy.
  • World Health Organization — Antenatal care recommendations.
  • Royal College of Obstetricians and Gynaecologists — Obstetric cholestasis guidance.
  • Hematology and obstetric guidelines on anemia, hemoglobinopathies, and carrier screening in pregnancy.

Available Tests & Panels

Your Prenatal Health Tests menu is pre-populated in the Ulta Lab Tests system. Begin with a core prenatal panel early in pregnancy. Use filters to add glucose screening (per clinician), thyroid tests, iron studies, urine protein/Cr, and bile acids based on your stage and history. Follow any collection instructions and review results with your prenatal clinician to align labs with ultrasound, fetal testing, and your delivery plan.

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The Estrogen Total Test measures all forms of estrogen in blood, including estradiol, estrone, and estriol, to assess reproductive and hormonal health. Abnormal levels may indicate menstrual irregularities, menopause status, infertility, or hormone-related disorders. Doctors order this test to evaluate fertility, monitor hormone therapy, and investigate symptoms such as hot flashes, irregular cycles, or abnormal bleeding. It provides key insight into endocrine and reproductive function.

Blood
Blood Draw
Also Known As: Total Estrogen Test, Estrogen Serum Test

Most Popular

The Estrone (E1) Test measures estrone, one of the three main estrogen hormones, to assess reproductive and hormonal health. It helps evaluate ovarian function, menstrual irregularities, menopause status, and estrogen-related disorders. In men, estrone testing may detect hormonal imbalances or excess estrogen. Doctors use this test to monitor hormone therapy, fertility treatments, and conditions affecting bone health, metabolism, and overall endocrine balance.

Blood
Blood Draw
Also Known As: E1 Test, Estrogen 1 Test

Most Popular

The Ferritin Test measures ferritin, a protein that stores iron in the body, to evaluate iron levels and detect deficiency or overload. It helps diagnose anemia, iron deficiency, hemochromatosis, and chronic disease-related inflammation. Doctors often order the ferritin test to investigate fatigue, weakness, or unexplained symptoms. It is also used to monitor iron supplementation, treatment effectiveness, and overall iron metabolism health.

Blood
Blood Draw
Also Known As: Iron Storage Test

Most Popular

The Folate RBC Test measures folate levels inside red blood cells, providing a more accurate reflection of long-term folate status than serum tests. Folate is essential for DNA synthesis, red blood cell production, and nervous system health. Low levels may indicate poor diet, malabsorption, or anemia. Doctors order this test for patients with fatigue, weakness, or neurological issues. Results help diagnose folate deficiency and guide nutritional treatment.

Blood
Blood Draw
Also Known As: RBC Folic Acid Test, Vitamin B9 RBC Test, Folate Test

Most Popular

The GGT Test measures gamma-glutamyl transferase, an enzyme found in the liver and bile ducts, to evaluate liver health. Elevated GGT may indicate liver disease, bile duct obstruction, alcohol use, or medication side effects. Doctors order this test to investigate symptoms like fatigue, jaundice, dark urine, or abdominal pain and to monitor liver damage. It is often performed with other liver tests to provide a complete picture of liver and bile duct function.

Blood
Blood Draw
Also Known As: Gamma Glutamyl Transferase Test, Gamma Glutamyl TransPeptidase Test, GGTP Test, GTP Test

Most Popular

The Glucose Test measures blood sugar levels to evaluate energy metabolism and screen for diabetes or prediabetes. Abnormal glucose may indicate hyperglycemia, hypoglycemia, or metabolic disorders. Doctors use this test during routine exams, to investigate symptoms like fatigue, excessive thirst, or frequent urination, and to monitor treatment for diabetes. It provides essential insight into how the body regulates blood sugar and overall metabolic health.

Blood
Blood Draw
Also Known As: Fasting Glucose Test, Fasting Blood Sugar Test

Most Popular

The Neisseria gonorrhoeae RNA TMA Urine Test detects gonorrhea infection by identifying bacterial RNA using transcription-mediated amplification. This highly sensitive urine test helps diagnose current gonorrhea infections, even in asymptomatic cases. Doctors use it for early detection, accurate diagnosis, and timely treatment to prevent complications. Results support effective STD management and help reduce the risk of transmission.

Varied
Phlebotomist
Also Known As: GC Test, Neisseria Gonorrhoeae test, Gonorrhoeae test, Gonorrhea Urine Test

The Hemoglobin A1c (HbA1c) Test measures average blood glucose over 2–3 months by detecting sugar attached to hemoglobin in red blood cells. It is used to diagnose diabetes, identify prediabetes, and monitor long-term blood sugar control. Doctors rely on the HbA1c test to evaluate treatment effectiveness, guide adjustments, and assess risk for complications, making it essential for diabetes care and metabolic health screening.

Blood
Blood Draw
Also Known As: A1c Test, HbA1c Test, Glycated Hemoglobin Test

The Hepatitis B Surface Antigen (HBsAg) Test with Reflex to Confirmation screens for hepatitis B surface antigen in blood and, if reactive, automatically performs confirmatory testing. A reactive confirmed result indicates an active hepatitis B infection, while a non-reactive result shows no infection. Doctors use this test to diagnose acute or chronic hepatitis B, investigate abnormal liver tests, and guide treatment, monitoring, and infection control decisions.

Blood
Blood Draw
Also Known As: HBsAg Test, Hep B Surface Ag Test, HBs Antigen Test, Hep B Test

The Herpes Simplex Virus 1 and 2 IgG Type-Specific Antibody HerpeSelect® Test detects IgG antibodies to HSV-1 and HSV-2, distinguishing between the two types. A positive result indicates past exposure, as IgG develops weeks after infection and remains long-term. Doctors use this test to confirm herpes diagnosis, guide treatment, or support sexual health decisions. Results provide vital insight into HSV status, infection history, and long-term immune response.

Blood
Blood Draw
Also Known As: Herpes 1 and 2 Test, Herpes IgG Test

Most Popular

The Homocysteine Test measures homocysteine levels in blood to assess risk for heart disease, stroke, and vascular problems. Elevated homocysteine may result from vitamin B6, B12, or folate deficiency and is linked to blood clots, cognitive decline, and osteoporosis. Doctors use this test to evaluate cardiovascular risk, monitor nutritional deficiencies, and guide treatment for metabolic or genetic conditions affecting homocysteine metabolism.

Blood
Blood Draw
Also Known As: Homocysteine Cardiac Risk Test

Most Popular

The Insulin Test measures insulin levels in blood to assess how the body regulates glucose and metabolism. It helps diagnose insulin resistance, hypoglycemia, type 2 diabetes, and metabolic syndrome. Doctors also use it to evaluate pancreatic function and monitor treatment effectiveness. Frequently ordered with glucose testing, the insulin test provides critical insight into endocrine health, blood sugar control, and risk for diabetes-related complications.

Blood
Blood Draw
Also Known As: Fasting Insulin Blood Test

The Iodine Serum/Plasma Test measures iodine levels in blood to evaluate thyroid health, hormone production, and nutritional balance. Abnormal levels may indicate iodine deficiency, leading to hypothyroidism or goiter, or excess iodine, which can disrupt thyroid function. Doctors use this test to investigate fatigue, weight changes, or thyroid disorders and to monitor supplementation. It provides valuable insight into endocrine, metabolic, and overall health.

Blood
Blood Draw
Also Known As: Iodine Test, Iodine Blood Test

The Lactate Dehydrogenase (LDH) Test measures LDH enzyme levels in blood to assess tissue damage and overall health. Elevated LDH may indicate conditions such as liver disease, heart attack, anemia, infections, or certain cancers, while low levels are uncommon. Doctors use this test to help diagnose disease, monitor treatment effectiveness, and track cell damage. It provides valuable insight into metabolic activity and organ function.

Blood
Blood Draw
Also Known As: LD Test, LDH Test, Lactic Acid Dehydrogenase Test

The Lipid Panel with Ratios Test measures seven key markers: total cholesterol, HDL, LDL, non-HDL cholesterol, triglycerides, Chol/HDL ratio, and LDL/HDL ratio. This advanced panel evaluates cardiovascular risk by assessing cholesterol balance and fat metabolism. Doctors use it to detect high cholesterol, atherosclerosis risk, and heart disease, and to monitor treatment. Often part of routine exams, it provides insight into long-term heart and metabolic health.

Also Known As: Lipid Profile Test, Cholesterol Panel Test, Lipid Blood Test

Most Popular

The Magnesium Serum Test measures magnesium levels in blood to evaluate electrolyte balance, nerve and muscle function, and overall metabolic health. Abnormal levels may indicate kidney disease, malnutrition, gastrointestinal disorders, or uncontrolled diabetes. Low magnesium can cause weakness, cramps, or irregular heartbeat, while high levels may signal kidney dysfunction. Doctors use this test to diagnose deficiencies, monitor therapy, or assess chronic health conditions.

Blood
Blood Draw
Also Known As: Mg Test, Mag Test

The Maternal AFP Test evaluates alpha-fetoprotein levels during pregnancy to assess fetal development and identify possible abnormalities. Variations in AFP may signal neural tube defects, abdominal wall issues, or genetic conditions such as trisomy 21. As part of prenatal screening, this test provides insight into maternal health and supports early evaluation of fetal growth and pregnancy outcomes.

Blood
Blood Draw
Also Known As: Maternal Alpha Fetoprotein Test

The Methylmalonic Acid (MMA) Blood Test measures MMA levels in the bloodstream to help detect vitamin B12 deficiency, often before anemia or neurological symptoms appear. Elevated results may indicate poor B12 absorption, pernicious anemia, or metabolic disorders. Doctors order this test when patients present with fatigue, neuropathy, or unexplained anemia. Results provide early insight into nutritional status, metabolic health, and treatment needs.

Blood
Blood Draw
Also Known As: MMA Test

The Phosphate (as Phosphorus) Test measures phosphorus levels in blood to evaluate bone strength, energy metabolism, and kidney health. Abnormal levels may indicate kidney disease, vitamin D imbalance, parathyroid disorders, or malnutrition. Doctors order this test to investigate fatigue, muscle weakness, or bone problems and to monitor conditions like chronic kidney disease. It provides key insight into metabolic, endocrine, and bone health.

Blood
Blood Draw
Also Known As: Phosphate Test, Phosphorus Test, PO4 Test

Most Popular

The Progesterone Test measures progesterone levels in blood to evaluate ovulation, fertility, and menstrual health. It helps confirm whether ovulation has occurred, assess causes of infertility, and monitor hormone therapy or high-risk pregnancies. Doctors also use it to investigate abnormal bleeding, detect ovarian or adrenal disorders, and evaluate miscarriage risk. This test provides key insight into reproductive, hormonal, and overall endocrine health.

Blood
Blood Draw
Also Known As: PGSN Test

The QuantiFERON-TB Gold Plus Test is a blood test that detects latent or active tuberculosis (TB) infection by measuring the immune response to TB antigens. It offers greater accuracy than the traditional skin test and avoids false positives from prior BCG vaccination. Doctors use it for TB screening, diagnosis, and monitoring in high-risk individuals. The QFT-Plus test is recommended for healthcare workers, travelers, and those exposed to TB.

Blood
Blood Draw
Also Known As: TB Test, Tuberculosis Test, IGRA Test

The RPR (Monitor) with Reflex to Titer Test screens for syphilis by detecting antibodies to Treponema pallidum. If positive, a reflex titer determines antibody concentration to assess disease activity and treatment response. Doctors order this test to diagnose syphilis, monitor therapy, or check reinfection. Results provide essential information for managing active infection, confirming treatment success, and guiding follow-up care.

Also Known As: Syphilis RPR Test, Rapid Plasma Reagin Test

The Rubella Titer Test measures IgG antibodies to determine immunity to rubella (German measles). A positive result indicates protection from prior infection or vaccination, while a negative result suggests susceptibility. Doctors order this test for women planning pregnancy, healthcare workers, students, or travelers. It helps confirm immune status, guide vaccination needs, and protect against congenital rubella syndrome and outbreak risks.

Blood
Blood Draw
Also Known As: Rubella IgG Antibody Test, Rubella Immune Status Test, German Measles Test, 3 Day Measles Test, Three Day Measles Test

The Testosterone Free and Total Test measures total testosterone and free, bioavailable testosterone in blood for both men and women. It helps diagnose hormone imbalance, infertility, low libido, erectile dysfunction in men, irregular periods, or PCOS in women. Doctors also order it to assess fatigue, mood changes, or muscle weakness and to monitor hormone therapy. This test provides key insight into reproductive, endocrine, and overall metabolic health.

Blood
Blood Draw
Also Known As: Bound and Unbound Testosterone, Uncapped Testosterone Test

Most Popular

The Thyroid Stimulating Hormone (TSH) Test measures TSH levels in blood to assess thyroid function and diagnose hypothyroidism or hyperthyroidism. It evaluates how the thyroid controls metabolism, energy, weight, and heart rate. Doctors use the TSH test to investigate symptoms such as fatigue, hair loss, or mood changes. Frequently included in routine health exams, it is also key for monitoring thyroid disease treatment and overall endocrine balance.

Blood
Blood Draw
Also Known As: Thyroid Stimulating Hormone Test, Thyrotropin Test

Prenatal care is one of the most widely and often utilized health care services to improve pregnancy outcomes in the U.S. Over 18 million prenatal health care visits happened in 2015 alone. A central part of this is prenatal testing.

What is prenatal testing, and how does it affect outcomes? Keep reading to learn how to promote prenatal health and empower your well-being.

What Is Prenatal Health Care?

Prenatal health care is an umbrella term covering multiple areas of medical treatment, checkups. It tests a person undergoes as soon as they become pregnant or believe they might be pregnant. The initial steps taken during the first 13 weeks, or the first trimester, often includes scheduling the first of multiple prenatal care checkups.

You can schedule these checkups with:

  • A trusted family doctor or your general physician
  • An OB/GYN (obstetrician or gynecologist) who specializes in reproductive health, pregnancy, prenatal care, and childbirth
  • An OB with training in maternal-fetal medicine if you are predisposed to a high-risk pregnancy
  • A certified midwife who is an advanced practice registered nurse that specializes in prenatal treatment, pregnancy, childbirth, and postpartum care

Whenever you consider seeing a new healthcare provider, consider your options and your needs. For example, is there anything in your medical history that could put you at risk for complications? Are you looking for someone to discuss prenatal genetic testing with?

Prenatal health care helps you have a pregnancy that is healthy and full-term. Your appointments will likely be more frequent in the first few weeks and near your due date. These checkups will repeat regularly to: 

  • Monitor fetal development
  • Check your vitals
  • Conduct tests
  • Administer medications or vaccines 

Risk Factors for Prenatal Health Issues

Many aspects of life can put a person at high risk for complications during pregnancy or childbirth. Some risk factors for prenatal health issues are environmental, such as exposure to endocrine-disrupting chemicals (EDCs). EDCs cause issues with the body's normal functions and hormone signaling.

EDCs are found in: 

  • Cigarette smoke
  • Air pollution
  • Pesticides and herbicides
  • BPA
  • Phthalates
  • Industrial products and waste

Fetuses exposed to EDCs are potentially at risk for poor outcomes or later-onset thyroid dysfunction. Levels of endocrine-disrupting chemicals can be measured in urine and fetal tube blood. However, the actual threat is still unknown.

Several pregnancy-related health issues can lead to complications, miscarriage, or stillbirth. Examples of these conditions include:  

  • Gestational diabetes mellitus (GDM)
  • Hyperthyroidism
  • Hypothyroidism
  • Poorly managed asthma
  • Folate deficiency
  • Heart disorders
  • Blood disorders

Pre-eclampsia (high blood pressure)Outcomes associated with pregnancy-related health issues are: 

  • Placental abnormalities
  • Premature delivery
  • Low birth weight
  • Macrosomia
  • Facial deformities
  • Fetal growth restriction (FGR)

Issues that Can Occur Affecting Prenatal Health

Another pregnancy-related health issue, folate deficiency, which is especially impactful during the first trimester, can lead to neural tube birth defects (NTDs) such as anencephaly or spina bifida. However, if folate deficiency or other pregnancy-related health issues are recognized early enough, you can receive treatment or make changes that lower the risk.

In 1998, the U.S. Food and Drug Administration (FDA) made changes that required manufacturers to fortify foods with 140 mcg folate to lower the risk of NTDs. Such food products include:

  • Cornmeal
  • Bread
  • Flours
  • Cereals
  • Pasta
  • Rice
  • Various grain products

A pregnant person may not get enough folate through diet alone and have to rely on prenatal supplements. The change in folate fortification leads to a decrease of neural tube defects by 50 percent in the U.S.

In addition to folate deficiency, a pregnant person is more likely to develop an iron deficiency or anemia. This is because a pregnant body must produce more blood to support the fetus, and the body may not be able to produce enough red blood cells. Iron is necessary for creating more red blood cells and staying healthy.  

What Are the Signs and Symptoms of Issues that Can Occur with Prenatal Health Issues?

Conditions affecting your health or the health of the fetus may not always show symptoms, but experienced doctors can typically see the signs. Signs and symptoms of potential issues include:

  • Bleeding, itching, or vaginal leakage
  • Severe pain in stomach or back
  • Blurry vision
  • Recurrent or intense headaches
  • Rash
  • Excessive vomiting or nausea
  • Fever above 101F
  • Painful urination
  • Swelling on one side of the body

Signs of dangerous conditions like ectopic pregnancy, when the fertilized egg develops outside of the uterus, may become apparent a few weeks in. The first symptoms are vaginal bleeding or spotting, pain in the pelvis, cramps, nausea, and pain in your neck or shoulder. It can be confirmed with a pelvic exam and an ultrasound.

Additionally, lab tests can check hCG levels. In the first trimester, hCG blood levels should double every few days. Abnormal hCG results could point to an ectopic pregnancy.

In later trimesters, your doctor may monitor fetal movement. Fetal movement count or kick count tests start around 20 weeks in. Your doctor will ask for you to feel for how often the fetus kicks.

You will keep track of the amount of time it takes to feel ten kicks or movements. Ten movements within one hour are typical.

The Lab Tests to Screen, Diagnose, and Monitor Prenatal Health Issues

Prenatal tests are regular procedures done to check on the health of you and the fetus and to detect congenital anomalies. Some tests are often repeated several times throughout the pregnancy. Here are some examples of routine prenatal tests:

Blood pressure: Regular blood pressure monitoring is essential for preventing or treating pre-eclampsia and the damage it causes.  

Urinalysis: This test checks your urine for infections, proteins, and glucose levels.  

hCG Total: hCG stands for human chorionic gonadotropin, a hormone that becomes detectable in the blood in the very early stages of pregnancy. Initial hCG testing checks for any amount of hCG to confirm pregnancy. Subsequent screenings track levels and totals to help track development and detect potential complications or signs of a miscarriage.

Complete Blood Count: CBC is a specific blood test that assesses the body's three primary blood cell types: white blood cells, red blood cells, and platelets. CBC panels are run as early as possible, ideally before conception, to look for signs of anemia, infection, or blood clotting issues. 

Blood Typing (ABO Group and Rh Type) Tests: You will have routine checks for infections, organ function, and hormone levels. Additionally, you may be tested to find out your blood type: A, B, AB, or O and your Rh factor—a compound present on the red blood cells of some people. You are either Rh-positive or Rh-negative. 

Understanding this is crucial because if you are Rh-negative with an Rh-positive fetus, both of you are at risk for hemolytic disease. To help prevent dangerous or fatal consequences, the drug RhoGAM is given to suppress the immune response that leads to hemolytic shock.  

Other routine tests include tracking your weight. These screenings often happen once (and usually during your first trimester):

Genetic Carrier Screening Tests: This test looks at samples of your saliva or blood for genetic markers indicating you are a carrier of genetic conditions that can affect your fetus. Carriers are unaffected but pass on the faulty genes. This is conducted before or in the first trimester.

Noninvasive Prenatal Testing: This test finds traces of fetal DNA in your blood. The fetal DNA is tested for genetic conditions like trisomy 13, trisomy 18, and trisomy 21 (Down syndrome). The results are typically accurate but not indisputable.

Measles, Mumps, and Rubella: These are highly infectious diseases that pose a serious risk to fetal health and development. Immunity testing is best done before becoming pregnant. Otherwise, this will be a part of your first prenatal checkup.  

TSH: Thyroid-stimulating hormone level testing occurs in the first trimester. Your prenatal healthcare provider will advise you on whether you need regular screenings. Those with hypothyroidism receive tests monthly until their 3rd trimester. 

Varicella-Zoster Virus: VZV is responsible for chickenpox and shingles infections. While chickenpox infections usually infect children who become immune, the virus can re-emerge as shingles later in life. Testing for VZV antibodies early on is necessary as the germ can cross the placenta and cause fetal defects or sickness. 

Some screening tests are conducted later in pregnancy. These occur during the second or third trimester: 

Chorionic Villus Sampling: Chorionic villus sampling (CVS) takes a sample of placenta tissue to test for genetic disorders. It is invasive, and potential side effects include cramping, bleeding, infection, preterm labor, and in rare cases, limb defects. This may happen late into the first trimester or early into the second. 

Amniocentesis: Similar to a CVS, amniocentesis tests amniotic fluid for lung development and infections. This screening tool can specifically uncover possible genetic conditions like chromosomal disorders, Tay-Sachs disease, muscular dystrophy, and cystic fibrosis. It is commonly run in the second or third trimester. 

Sexually Transmitted Infections (STIs)

STIs, such as HIV, gonorrhea, chlamydia, syphilis, hepatitis B and C, have pronounced consequences on pregnancy. Silent infections may lay dormant for years without symptoms. Proceeding with pregnancy with an untreated STI sharply increases the risk of miscarriage, stillbirth, early delivery, SIDS, brain damage, meningitis, and cirrhosis.

While you may deny routine testing of STIs in some areas of the country, screening is strongly recommended, at least during the first trimester. Subsequent tests are advisable for those at a higher risk.

Gestational Diabetes Mellitus

There are two common laboratory tests for gestational diabetes mellitus (GDM). The first test is run in the early weeks of pregnancy: 

Hemoglobin A1c: By checking hemoglobin A1c levels in the first trimester, it is potentially easier to predict GDM before it happens. Those with A1c levels in the "prediabetic" range will need regular blood glucose checks and monitoring. 

As you hit milestones in your pregnancy and make it past the second trimester, your chance of developing GDM rises. The placenta secretes necessary hormones that have an adverse effect in some, impacting how your body uses insulin.   

Blood Glucose: The first type of blood glucose test takes place over the span of an hour. You will ingest a drink high in glucose and have your blood glucose levels checked in one hour. By comparing these results to prior levels, a doctor gauges your risk of GDM. 

glucose challenge test followed by a two-hour glucose tolerance are methods for screening pregnant people and diagnosing GDM. This type of diabetes increases the risk of complications like premature birth, birth injury, respiratory distress syndrome, jaundice, and the need for a cesarean section. You are at a higher risk for GDM if:

  • You are older than 25
  • You have had GDM before
  • You have PCOS, hormonal imbalances, high blood pressure, or heart disease
  • You are prediabetic
  • You have a BMI of 25 or higher
  • You have a family history of diabetes

Your prenatal care provider can help identify what tests are right for you.

Frequently Asked Questions About Prenatal Health and Lab Testing for Prenatal Health

Prenatal lab testing helps parents-to-be understand whether their fetus is at risk for birth defects or genetic conditions. Here are some frequently asked questions about prenatal testing and their answers.

Why Do People Get Prenatal Tests?

Your prenatal healthcare provider may recommend screening or diagnostic tests during different trimesters to monitor your health and the development of the fetus. The types of tests may depend on your age, health, medical history, and other factors.

How Do I Get a Prenatal Test?

Ulta Lab Tests offers over 1,000 lab tests and a variety of wellness panels. You can order our tests online, have your blood drawn at a participating patient service center, and review your results online.

What Do I Do with the Results?

Regardless of whether your test results come back within normal ranges or contain abnormalities, we strongly urge you to see your doctor. In the case of prenatal care, you need to work with a specialist to understand the next best steps. Using your test results, a physician can provide you with an official diagnosis. 

Prenatal Testing with Ulta Lab Tests

Several factors, many of which are out of your control, impact your health and the health of your fetus. Help yourself with prenatal testing and by working with a trusted medical professional. 

Ulta Lab Tests offers tests that are accurate and reliable. You will get secure, confidential results without insurance or a referral at affordable prices when you order your testing with Ulta Lab Tests. You can order your comprehensive obstetric and prenatal lab tests and receive your results online within 24 to 48 hours for most tests.

Take control of your health with Ulta Lab Tests today!