Ugt1a1 Gene Polymorphism (Ta Repeat)

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Ugt1a1 Gene Polymorphism Ta Repeat

Ugt1a1 Ta Repeat

*Important Information on Lab Test Processing Times: Ulta Lab Tests is committed to informing you about the processing times for your lab tests processed through Quest Diagnostics. Please note that the estimated processing time for each test, indicated in business days, is based on data from the past 30 days across the 13 Quest Diagnostics laboratories for each test. These estimates are intended to serve as a guide and are not guarantees. Factors such as laboratory workload, weather conditions, holidays, and the need for additional testing or maintenance can influence actual processing times. We aim to offer estimates to help you plan accordingly. Please understand that these times may vary, and processing times are not guaranteed. Thank you for choosing Ulta Lab Tests for your laboratory needs.

The Ugt1a1 Gene Polymorphism (Ta Repeat) test contains 1 test with 1 biomarker.

Uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) is primarily responsible for the glucuronidation and detoxification of SN-38, the active metabolite of irinotecan (Camptosar), used in the treatment of colorectal cancer. The TA-7 variant referred to as UGT1A1*28, is associated with reduced SN-38 glucuronidation and increased toxicity. Individuals homozygous for the UGT1A1*28 (TA-7) allele have Gilbert syndrome which is a mild form of hyperbilirubinemia.

Customer Reviews