Thyroid Panel with Ferritin and Vitamin D

The Thyroid Panel with Ferritin and Vitamin D panel contains 6 tests with 11 biomarkers.

Brief Description: The Thyroid Panel with Ferritin and Vitamin D is a specialized set of tests designed to evaluate thyroid function, iron storage, and vitamin D levels. This panel is integral for assessing the intricate relationship between thyroid health, iron metabolism, and bone health, offering a comprehensive overview that extends beyond standard thyroid testing. By combining these specific tests, healthcare providers can gain insights into a patient's overall endocrine function and nutritional status, which are critical for diagnosing and managing various health conditions.

Collection Method: Blood Draw

Specimen Type: Serum

Test Preparation: Fasting Specimen is preferred.

Specifc to TSH: Specimen collection after fluorescein dye angiography should be delayed for at least 3 days. For patients on hemodialysis, specimen collection should be delayed for 2 weeks.

According to the assay manufacturer Siemens: "Samples containing fluorescein can produce falsely depressed values when tested with the Advia Centaur TSH3 Ultra assay."

When and Why the Thyroid Panel with Ferritin and Vitamin D May Be Ordered.

Healthcare professionals may order the Thyroid Panel with Ferritin and Vitamin D for individuals presenting with symptoms suggestive of thyroid disorders, such as fatigue, weight changes, temperature sensitivity, and hair loss. It's also recommended for those with signs of iron deficiency or vitamin D insufficiency and for patients with known thyroid conditions to monitor treatment efficacy and adjust therapy as needed.

What the Panel Checks For

  • Ferritin: This test measures the level of ferritin in the blood, providing an estimate of the body's iron stores. Ferritin is crucial for diagnosing iron deficiency anemia and understanding its potential impact on thyroid function.

  • QuestAssureD 25-Hydroxyvitamin D Total with D2 and D3: This test assesses levels of vitamin D, essential for bone health, immune function, and, indirectly, thyroid health, given vitamin D's role in modulating autoimmune responses.

  • T3 Free: Free T3 levels provide insights into the active thyroid hormone available in the body, crucial for diagnosing hyperthyroidism or hypothyroidism.

  • T4 Free: This test measures the free T4 levels, offering a direct indicator of thyroid gland function and its ability to produce thyroid hormone.

  • Thyroid Peroxidase Antibodies (TPO): TPO antibodies are tested to identify autoimmune thyroid diseases like Hashimoto's thyroiditis, where the immune system attacks thyroid tissue.

  • Thyroglobulin Antibodies (TgAb): This test checks for antibodies against thyroglobulin, another marker for autoimmune thyroid conditions.

  • Thyroid Stimulating Hormone (TSH): TSH levels are a primary indicator of thyroid health, with deviations from the norm suggesting hyperthyroidism or hypothyroidism.

Conditions and Diseases Detected

This comprehensive panel can help in diagnosing and managing:

  • Thyroid disorders: Conditions such as hypothyroidism, hyperthyroidism, and autoimmune thyroid diseases (Hashimoto's thyroiditis and Graves' disease) can be identified through abnormalities in TSH, T3, T4, and thyroid antibody levels.
  • Iron deficiency anemia: Low ferritin levels can indicate inadequate iron stores, affecting overall health and potentially thyroid function.
  • Vitamin D deficiency: Insufficient levels of vitamin D are linked to a host of health issues, including bone disorders and an increased risk of autoimmune diseases.

Clinical Applications

Healthcare providers use the results from the Thyroid Panel with Ferritin and Vitamin D to:

  • Diagnose underlying thyroid disorders, guiding treatment decisions such as thyroid hormone replacement or antithyroid medications.
  • Identify and address iron deficiency anemia, potentially through dietary changes or iron supplementation.
  • Correct vitamin D deficiency with vitamin D supplementation, thereby supporting bone health and possibly modulating immune responses in autoimmune thyroid conditions.

The Thyroid Panel with Ferritin and Vitamin D is a critical diagnostic tool that offers a multifaceted view of a patient's endocrine and nutritional health. By providing a detailed analysis of thyroid function alongside iron and vitamin D status, this panel aids in the comprehensive assessment and management of thyroid-related disorders, ensuring targeted and effective treatment strategies for optimal patient outcomes.

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Ferritin

Ferritin is a protein found inside cells that stores iron so your body can use it later. A ferritin test indirectly measures the amount of iron in your blood. The amount of ferritin in your blood (serum ferritin level) is directly related to the amount of iron stored in your body.

Vitamin D, 25-Oh, D2

Vitamin D2 ((ergocalciferol,) is found in fortified foods and in most vitamin preparations and supplements. Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. The D2 form is found in fortified foods and in most vitamin preparations and supplements. Vitamin D2 is effective when it is converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Vitamin D, 25-Oh, D3

Vitamin D3 (cholecalcifero) which comes from animals. Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. Vitamin D3 is the form produced in the body and is also used in some supplements. Vitamin D3 are is converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Vitamin D, 25-Oh, Total

Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. The chemical structures of the types of vitamin D are slightly different, and they are named vitamin D2 (ergocalciferol, which comes from plants) and vitamin D3 (cholecalciferol, which comes from animals). The D2 form is found in fortified foods and in most vitamin preparations and supplements. Vitamin D3 is the form produced in the body and is also used in some supplements. Vitamin D2 and D3 are equally effective when they are converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Vitamin D, 25-Oh, Total

Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. The chemical structures of the types of vitamin D are slightly different, and they are named vitamin D2 (ergocalciferol, which comes from plants) and vitamin D3 (cholecalciferol, which comes from animals). The D2 form is found in fortified foods and in most vitamin preparations and supplements. Vitamin D3 is the form produced in the body and is also used in some supplements. Vitamin D2 and D3 are equally effective when they are converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Also known as: Free T3, FT3, T3 Free

T3, Free

This test measures the amount of triiodothyronine, or T3, in the blood.

Also known as: Free T4, FT4, T4 Free

T4, Free

The free T4 test is not affected by protein levels. Since free T4 is the active form of thyroxine, the free T4 test is may be a more accurate reflection of thyroid hormone function.

Thyroglobulin Antibodies

Measurement of thyroglobulin antibodies is useful in the diagnosis and management of a variety of thyroid disorders including Hashimoto's thyroiditis, Graves Disease and certain types of goiter.

Thyroid Peroxidase

Also known as: Thyroid Stimulating Hormone, Thyroid Stimulating Hormone (TSH), Thyrotropin

TSH

A TSH test is a lab test that measures the amount of thyroid stimulating hormone (TSH) in your blood. TSH is produced by the pituitary gland. It tells the thyroid gland to make and release thyroid hormones into the blood.

TSH

*Process times are an estimate and are not guaranteed. The lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

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