The Nicotine and Expanded Metabolites, LC/MS/MS test contains 1 test with 3 biomarkers.
This assay is used for the detection of nicotine and two primary metabolites, 3-OH cotinine and cotinine in serum and plasma to determine the tobacco exposure status of an individual. Nicotine has a short half-life of approximately sixty minutes; Its presence may indicate recent tobacco exposure. The half-life of the primary metabolites is longer and provides a larger window of detection for tobacco exposure. Individuals exposed to passive tobacco smoke (environmental or second-hand) can have detectable concentrations of nicotine and its metabolites depending on the type of exposure. The ranges of concentrations related to passive exposure are not well established but normally are less than those attributed to active tobacco users.