Helicobacter Pylori Ag, Eia, Stool

The Helicobacter Pylori Ag, Eia, Stool test contains 1 test with 1 biomarker.

Description: The H Pylori antigen test is used to detect the bacteria, helicobacter pylori, that is a major cause of peptic ulcer disease.

Also Known As: H. Pylori Antigen Test, Stool Antigen Test

Collection Method: Patient Self Collection Kit provided by Patient Service Center

Specimen Type: Stool (Feces)

Test Preparation: Patient Self Collection Required – Instructions Below

  1. Patient to visit a Quest Patient Service Center to obtain the designated sterile collection container required for the test.
  2. Patient self-collects stool sample off site from PSC.
  3. Patient self-collects 0.5 mL or 0.5 grams of semi-solid stool or 20 mm diameter solid stool and transfer to properly labeled plastic, leak-proof container.
  4. Label the specimen collection container: a. Record the date and time on the specimen collection. b. Record the patient’s full name as on requisition and DOB.
  5. IMPORTANT: Watery, diarrheal stool is not acceptable.
  6. IMPORTANT: The stool sample must be refrigerated immediately after collection.
  7. The stool specimen must be packed with cold packs and returned to the Quest Patient Service Center with the Patient Requisition within 24 hours of collection.

Patient Preparation

For initial diagnostic purposes no special patient preparation is required. Patients are not required to be off of medications or to fast before this test. While positive test results from patients taking agents such as proton pump inhibitors and antimicrobials should be considered accurate, false negative results may be obtained. For this reason, physicians may suggest the patient go off medications for two weeks and repeat test if negative results are obtained.

To confirm eradication, testing should be done at least 4 weeks following the completion of treatment. However, a positive test result 7 days’ post therapy is indicative of treatment failure.

When is a Helicobacter Pylori test ordered:

When someone complains of stomach pain and exhibits ulcer-related symptoms, testing may be required.

When an individual has finished taking the recommended course of antibiotics, H. pylori tests may also be requested to ensure that the H. pylori bacteria have been eradicated. However, not every patient has a follow-up examination.

What does a Helicobacter Pylori stool test check for?

An organism known as Helicobacter pylori is a major contributor to the development of peptic ulcer disease. Testing for H. pylori identifies a gastrointestinal infection brought on by the bacteria.

H. pylori is quite widespread, particularly in underdeveloped nations. As much as 50% of people on the planet have the bacteria in their stomachs and intestines. The majority of persons affected by H. pylori will never have any symptoms, although it does raise the risk of stomach cancer, chronic gastritis, and ulcers. Due to the bacteria, the stomach is less able to generate mucus, which increases the risk of acid damage and peptic ulcers.

It is not advised to perform an antibody test on blood samples for routine diagnosis or to assess the efficacy of treatment. This test does not differentiate between a current illness and a former infection; it only finds antibodies to the bacterium. It is improbable that a person has ever had an infection with H. pylori if the antibody test is negative. A stool antigen or breath test should be used to validate results if they are ordered and positive.

Lab tests often ordered with a Helicobacter Pylori test:

  • Gastrin

Conditions where a Helicobacter Pylori test is recommended:

  • Peptic Ulcer

How does my health care provider use a Helicobacter Pylori test?

Testing for Helicobacter pylori is used to identify bacterial infections and assess how well a treatment is working. A H. pylori infection is linked to a higher risk of stomach cancer, chronic gastritis, and ulcers.

For the diagnosis of an H. pylori infection and the assessment of the efficacy of treatment, the stool antigen test and urea breath test are advised. Because they are quick and noninvasive, these tests are the ones that are used the most. Invasive endoscopy-related tests can also be used to identify and assess H. pylori, but they are less typically used as a result.

What do my H Pylori test results mean?

When a person's stool antigen or breath test for H. pylori is positive, it is likely that the bacteria are to blame for their peptic ulcer. To eradicate the germs and halt the pain and ulceration, a course of treatment combining antibiotics and other drugs will be advised.

If a test is negative, it is quite improbable that the subject has an H. pylori infection, and it is possible that the subject's signs and symptoms are caused by something else. To more definitively rule out infection, additional testing, such as a more invasive tissue biopsy, may be performed if symptoms continue.

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Helicobacter Pylori Ag Eia Stool


*Process times are an estimate and are not guaranteed. The lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

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