Direct LDL Most Popular

The Direct LDL test contains 1 test with 1 biomarker.

Description: Direct LDL is a blood test that measures LDL cholesterol in your blood’s serum to determine risk of heart  disease.

Also Known As: Direct LDL-C Test, Direct LDL Cholesterol Test, DLDL Test, LDL D Test

Collection Method: Blood Draw

Specimen Type: Serum

Test Preparation: If an LDL-cholesterol measurement is to be performed along with triglycerides, the patient should be fasting 9-12 hours prior to collection

When is a Direct LDL test ordered?

When calculating LDL cholesterol is impossible due to a considerable increase in triglycerides, a direct LDL-C test is ordered. A doctor may order it if previous tests have revealed elevated triglyceride levels. When triglyceride levels are too high to calculate LDL-C, certain laboratories will automatically do this direct LDL test. This saves the doctor time by avoiding the need to order another test, the patient time by avoiding the need for a second blood sample, and the time it takes to get the test results.

What does a Direct LDL blood test check for?

The direct low-density lipoprotein cholesterol test determines the amount of LDL cholesterol in the blood, also known as "bad" cholesterol. LDL-C levels beyond a certain threshold are linked to an increased risk of artery hardening and heart disease. The amount of LDL-C is usually determined using readings from a typical lipid profile. This is a good estimate of LDL-C in most circumstances, although it becomes less accurate as triglyceride levels rise. When triglycerides are high, direct measurement of LDL-C is less impacted by them and can be employed.

Lab tests often ordered with a Direct LDL test:

  • LDL Cholesterol
  • Lipid Panel
  • Total Cholesterol
  • Triglycerides
  • HDL Cholesterol
  • Apolipoprotein B
  • Apolipoprotein A1
  • Lipoprotein Fractionation Ion Mobility

Conditions where a Direct LDL test is recommended:

  • Heart Disease
  • Coronary Artery Diseases

How does my health care provider use a Direct LDL test?

Low density lipoprotein cholesterol levels are commonly used to determine a person's risk of heart disease or to monitor their response to cholesterol-lowering medication. Total cholesterol, high-density lipoprotein cholesterol, and triglycerides are all assessed in a conventional lipid profile. The amount of cholesterol present in low-density lipoprotein can be calculated using a mathematical calculation based on the three observed values. The calculated LDL-C value is often included in the lipid profile. The calculation is no longer applicable when triglycerides are high. The only way to precisely determine LDL-C in this case is to measure it directly.

A metabolic disease affecting lipids could cause high triglycerides. After eating, though, anyone can have high triglycerides. The direct LDL-C test can identify the amount of LDL in a person's blood in either condition.

What do my Direct LDL test results mean?

Increased LDL levels, as determined by the direct LDL-C test, suggest a higher risk of heart disease. Reduced levels imply a reduction in the risk of heart disease as a result of lipid-lowering lifestyle adjustments and/or pharmacological therapy.

Low LDL levels are usually not a cause for worry and are not monitored. They can appear in persons who have a hereditary lipoprotein insufficiency, as well as in people who have hyperthyroidism, infection, or inflammation.

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Cholesterol, LDL, LDL, LDL Cholesterol, Direct, Low Density Lipoprotein

Direct LDL

The test for low-density lipoprotein cholesterol (LDL-C) is used as part of a lipid profile to predict an individual's risk of developing heart disease. The LDL cholesterol is considered the most important form in determining risk of heart disease. LDL values amy be used to monitor levels after the start of diet or exercise programs or to determine whether or not prescribing one of the lipid-lowering drugs, such as statins, would be useful.
*Process times are an estimate and are not guaranteed. The lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

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