Compare - Perimenopause Test (EW)

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The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.


Estradiol (estradiol-17 beta, E2) is part of an estrogen that is a group of steroids that regulate the menstrual cycle and function as the main female sex hormones. Estrogens are responsible for the development of female sex organs and secondary sex characteristics and are tied to the menstrual cycle and pregnancy. They are considered the main sex hormones in women and are present in small quantities in men. Estradiol (E2) is the predominant form of estrogen and is produced primarily in the ovaries with additional amounts produced by the adrenal glands in women and in the testes and adrenal glands in men. Estradiol levels are used in evaluating ovarian function. Estradiol levels are increased in cases of early (precocious) puberty in girls and gynecomastia in men. Its main use has been in the differential diagnosis of amenorrhea – for example, to determine whether the cause is menopause, pregnancy, or a medical problem. In assisted reproductive technology (ART), serial measurements are used to monitor follicle development in the ovary in the days prior to in vitro fertilization. Estradiol is also sometimes used to monitor menopausal hormone replacement therapy.

Also known as: Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH), Follicle Stimulating Hormone and Luteinizing Hormone



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The Compare - Perimenopause Test (EW) panel contains 2 tests with 3 biomarkers.

Why pay $99 for Everlywell's Perimenopause finger prick test kit when you can experience the convenience and affordablity of a Perimenopause lab test with Ulta Lab Tests - compare now and save!

Brief Description: The Perimenopause Lab Test is a diagnostic panel that includes the measurement of specific hormones, such as Estradiol, Follicle Stimulating Hormone (FSH), and Luteinizing Hormone (LH). This test is designed to assess hormonal changes that occur during the perimenopausal transition in women.

This test is not intended for patients under the age of 18 years old. For patients under 18 years old, order Estradiol, Ultrasensitive LC/MS/MS #30289. If Estradiol #4021 is ordered for a patient under 18, the lab will automatically change the code to and charge for Estradiol, Ultrasensitive LC/MS/MS #30289 at an additional charge of $34.

Collection Method: Blood Draw

Specimen Type: Serum

Test Preparation: No preparation required

Note: For any patients for whom low estradiol levels are anticipated (e.g. males, pre-pubertal children and hypogonadal/post-menopausal females), the Estradiol, Ultrasensitive, LC/MS/MS #30289 assay is recommended.

When and Why the Perimenopause Lab Test May Be Ordered

Timing of the Test: The Perimenopause Lab Test is typically ordered when a woman is experiencing symptoms or signs of perimenopause, which is the transitional period leading up to menopause. Perimenopause can start in a woman's 40s and can last for several years.

Reasons for Ordering the Test:

  1. Assessment of Hormonal Changes: The primary purpose of this test is to assess hormonal changes that occur during perimenopause. It helps healthcare providers understand the hormonal fluctuations, particularly in Estradiol, FSH, and LH levels.

  2. Confirmation of Perimenopause: Women who are experiencing symptoms like irregular menstrual cycles, hot flashes, night sweats, mood changes, or vaginal dryness may undergo this test to confirm if they are indeed in the perimenopausal phase.

  3. Management of Symptoms: Test results can guide healthcare providers in managing perimenopausal symptoms. For example, if Estradiol levels are declining, hormone replacement therapy (HRT) may be considered to alleviate symptoms.

  4. Family Planning: For women who are still sexually active and not yet ready for menopause, the test results can help with family planning decisions and contraception choices.

What the Perimenopause Lab Test Checks For

The Perimenopause Lab Test checks for:

Estradiol: Estradiol is a form of estrogen produced by the ovaries. During perimenopause, Estradiol levels fluctuate and eventually decline. Low Estradiol levels can contribute to various perimenopausal symptoms.

Follicle Stimulating Hormone (FSH): FSH is produced by the pituitary gland and is involved in regulating the menstrual cycle. In perimenopause, FSH levels often rise, reflecting the body's attempt to stimulate the ovaries to produce more estrogen.

Luteinizing Hormone (LH): LH, like FSH, plays a role in regulating the menstrual cycle. In perimenopause, LH levels may also increase as the body tries to compensate for declining estrogen production.

How Health Care Providers Use the Results of the Perimenopause Lab Test

Healthcare providers use the results of the Perimenopause Lab Test to:

  1. Confirm Perimenopause: Elevated FSH and LH levels, along with lower Estradiol levels, can confirm that a woman is in the perimenopausal phase.

  2. Manage Symptoms: Understanding hormone levels helps providers tailor symptom management strategies, such as hormone replacement therapy (HRT), lifestyle changes, or alternative therapies to alleviate perimenopausal symptoms.

  3. Family Planning: For women who wish to continue family planning during perimenopause, the test results can inform contraceptive choices.

  4. Monitor Hormone Replacement Therapy: For those undergoing HRT, regular monitoring of hormone levels ensures that therapy is appropriately adjusted to maintain hormonal balance.

In summary, the Perimenopause Lab Test is a valuable tool for assessing hormonal changes during the perimenopausal transition. It aids in confirming perimenopause, managing associated symptoms, guiding family planning, and monitoring hormone replacement therapy for women in this phase of life.

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.

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