Advanced Cholesterol Panel + Inflammatory Marker

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Apolipoprotein B Cardio IQ, Cardio IQ Apolipoprotein B

Apolipoprotein B

Also known as: Cardio IQ hs-CRP , hsCRP Cardio IQ

Hs Crp

A high-sensitivity CRP (hs-CRP) test may be used by itself, in combination with other cardiac risk markers, or in combination with a lipoprotein-associated phospholipase A2 (Lp-PLA2) test that evaluates vascular inflammation. The hs-CRP test accurately detects low concentrations of C-reactive protein to help predict a healthy person's risk of cardiovascular disease (CVD). High-sensitivity CRP is promoted by some as a test for determining a person's risk level for CVD, heart attacks, and strokes. The current thinking is that hs-CRP can play a role in the evaluation process before a person develops one of these health problems.

Also known as: Cardio IQ Lipid Panel, Lipid Panel Cardio IQ, Lipids

Chol/HDLC Ratio

Cholesterol, Total

Cholesterol is a waxy, fat-like substance that occurs naturally in all parts of the body. Your body needs some cholesterol to work properly. But if you have too much in your blood, it can combine with other substances in the blood and stick to the walls of your arteries. This is called plaque. Plaque can narrow your arteries or even block them. High levels of cholesterol in the blood can increase your risk of heart disease. Your cholesterol levels tend to rise as you get older. There are usually no signs or symptoms that you have high blood cholesterol, but it can be detected with a blood test. You are likely to have high cholesterol if members of your family have it, if you are overweight or if you eat a lot of fatty foods. You can lower your cholesterol by exercising more and eating more fruits and vegetables. You also may need to take medicine to lower your cholesterol.

HDL Cholesterol


Non HDL Cholesterol


Triglycerides are a form of fat and a major source of energy for the body. This test measures the amount of triglycerides in the blood. Most triglycerides are found in fat (adipose) tissue, but some triglycerides circulate in the blood to provide fuel for muscles to work. After a person eats, an increased level of triglycerides is found in the blood as the body converts the energy not needed right away into fat. Triglycerides move via the blood from the gut to adipose tissue for storage. In between meals, triglycerides are released from fat tissue to be used as an energy source for the body. Most triglycerides are carried in the blood by lipoproteins called very low density lipoproteins (VLDL). High levels of triglycerides in the blood are associated with an increased risk of developing cardiovascular disease (CVD), although the reason for this is not well understood. Certain factors can contribute to high triglyceride levels and to risk of CVD, including lack of exercise, being overweight, smoking cigarettes, consuming excess alcohol, and medical conditions such as diabetes and kidney disease.

Also known as: Cardio IQ Lipoprotein (a), Lipoprotein a Cardio IQ

Lipoprotein (A)

Lipoprotein-a, or Lp(a) are molecules made of proteins and fat. They carry cholesterol and similar substances through the blood. A high level of Lp(a) is considered a risk factor for heart disease. High levels of lipoproteins can increase the risk of heart disease. The test is done to check your risk of atherosclerosis, stroke, and heart attack.

Also known as: Ion Mobility, Cardio IQ Lipoprotein Fractionation, Ion Mobility , HDL Subfractions, IDL Subfractions, LDL Subfractions, Lipoprotein Fraction, Lipoprotein Fractionation, Lipoprotein Fractionation Ion Mobility Cardio IQ, Quest Diagnostics has replaced the VAP® Cholesterol Test with Lipoprotein Fractionation, Ion Mobility, Cardio IQ™ test

HDL Large

LDL Medium

LDL Particle Number

LDL Pattern

LDL Peak Size

LDL Small

*Important Information on Lab Test Processing Times: Ulta Lab Tests is committed to informing you about the processing times for your lab tests processed through Quest Diagnostics. Please note that the estimated processing time for each test, indicated in business days, is based on data from the past 30 days across the 13 Quest Diagnostics laboratories for each test. These estimates are intended to serve as a guide and are not guarantees. Factors such as laboratory workload, weather conditions, holidays, and the need for additional testing or maintenance can influence actual processing times. We aim to offer estimates to help you plan accordingly. Please understand that these times may vary, and processing times are not guaranteed. Thank you for choosing Ulta Lab Tests for your laboratory needs.

The Advanced Cholesterol Panel + Inflammatory Marker panel contains 5 tests with 15 biomarkers.

Brief Description: The Advanced Cholesterol Panel + Inflammatory Marker Panel is a sophisticated diagnostic tool designed to evaluate cardiovascular risk from multiple dimensions. This comprehensive assessment combines traditional lipid profiling with advanced biomarkers for atherosclerosis and inflammation, offering a deep dive into an individual’s lipid metabolism and cardiovascular health. The integration of these tests provides a nuanced view of both the quantity and quality of cholesterol particles and the presence of inflammation, which is a known risk factor for cardiovascular diseases.

Collection Method: Blood Draw

Specimen Type: Serum

Test Preparation: Fasting for at least 12 hours is required.

When and Why the Advanced Cholesterol Panel + Inflammatory Marker Panel May Be Ordered

This panel is typically ordered for individuals at moderate to high risk of cardiovascular disease, including those with a family history of heart disease, existing heart disease, diabetes, or hypertension. It is also recommended for those who may not have apparent risk factors but whose lifestyle—such as poor diet, physical inactivity, or smoking—might contribute to increased cardiovascular risk. The panel is crucial for guiding interventions and monitoring the effectiveness of treatments aimed at reducing cardiovascular risk.

What the Advanced Cholesterol Panel + Inflammatory Marker Panel Checks For

Each component of the panel provides critical information on cardiovascular health risks:

  • Apolipoprotein B: This test measures the level of apolipoprotein B, a primary protein found in low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL). High levels are directly associated with a greater risk of cardiovascular disease as ApoB particles are the ones most likely to contribute to plaque formation in the arteries.

  • High Sensitivity C-Reactive Protein (hs-CRP): hs-CRP is a test that measures low levels of inflammation in the body. Chronic inflammation is linked to an increased risk of heart disease, and this test can be a predictor of future cardiovascular events.

  • Lipid Panel: This comprehensive test measures total cholesterol, high-density lipoprotein (HDL) cholesterol, LDL cholesterol, and triglycerides. It provides a baseline for understanding an individual’s risk of developing heart disease.

  • Lipoprotein (a): This test measures the level of lipoprotein (a), a particle that carries cholesterol and is similar to LDL. Elevated levels are considered a genetic risk factor for atherosclerosis.

  • Ion Mobility Lipoprotein Fractionation: This advanced test separates lipoprotein particles into subgroups by size and density. It allows for a more precise analysis of lipid risk factors, particularly identifying small, dense LDL particles that are more atherogenic.

Conditions and Diseases Detected by the Panel

The panel aids in the detection and management of several cardiovascular conditions:

  • Coronary Heart Disease: Elevated ApoB, high levels of small, dense LDL particles, and a high hs-CRP level are significant markers for coronary artery disease, indicating increased risk of clogged arteries.

  • Stroke: Elevated Lipoprotein (a) and inflammatory markers like hs-CRP can indicate an increased risk of stroke due to atherosclerosis and vascular inflammation.

  • Peripheral Artery Disease: Similar to coronary heart disease, the imbalance in lipid profiles, especially high levels of ApoB and low HDL, can predict peripheral artery disease.

Using the Results of the Advanced Cholesterol Panel + Inflammatory Marker Panel

Healthcare professionals use the results from this panel to:

  • Refine Risk Assessment: By understanding the detailed lipid profile and inflammatory status, clinicians can better estimate the cardiovascular risk, which is crucial for preventive strategies.

  • Tailor Treatment Approaches: Results can guide the prescription of statins, lifestyle changes, or other interventions based on specific lipid abnormalities or inflammation levels.

  • Monitor Treatment Efficacy: Ongoing assessments with the panel help evaluate the success of lifestyle changes or medications in altering lipid profiles and reducing inflammation.

The Advanced Cholesterol Panel + Inflammatory Marker Panel is an invaluable tool in modern preventive cardiology. It goes beyond traditional cholesterol testing by providing detailed insights into lipid particle behavior and inflammatory status, thus offering a more comprehensive assessment of cardiovascular risk. This enhanced understanding allows for more targeted interventions and personalized treatment plans, ultimately aiming to reduce the incidence and severity of cardiovascular disease.

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.

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