Advanced Blood Sugar Monitoring - Advanced

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.


Also known as: 3 HR Glucose Tolerance, 3 HR GTT (4 Specimens, Glucose Tolerance 3 HR, Glucose Tolerance Test 4 Specimens, Non-pregnant

Glucose, Specimen 1

Glucose, Specimen 2

Glucose, Specimen 3

Glucose, Specimen 4

Glucose, Time 1

Also known as: Glutamic Acid Decarboxylase65 Antibody

Glutamic Acid


Also known as: A1c, Glycated Hemoglobin, Glycohemoglobin, Glycosylated Hemoglobin, HA1c, HbA1c, Hemoglobin A1c, Hemoglobin A1c HgbA1C, Hgb A1c

Hemoglobin A1c

The A1c test evaluates the average amount of glucose in the blood over the last 2 to 3 months. It does this by measuring the concentration of glycated (also often called glycosylated) hemoglobin A1c. Hemoglobin is an oxygen-transporting protein found inside red blood cells (RBCs). There are several types of normal hemoglobin, but the predominant form – about 95-98% – is hemoglobin A. As glucose circulates in the blood, some of it spontaneously binds to hemoglobin A. The hemoglobin molecules with attached glucose are called glycated hemoglobin. The higher the concentration of glucose in the blood, the more glycated hemoglobin is formed. Once the glucose binds to the hemoglobin, it remains there for the life of the red blood cell – normally about 120 days. The predominant form of glycated hemoglobin is referred to as HbA1c or A1c. A1c is produced on a daily basis and slowly cleared from the blood as older RBCs die and younger RBCs (with non-glycated hemoglobin) take their place. This test is used to monitor treatment in someone who has been diagnosed with diabetes. It helps to evaluate how well their glucose levels have been controlled by treatment over time. This test may be used to screen for and diagnose diabetes or risk of developing diabetes. In 2010, clinical practice guidelines from the American Diabetes Association (ADA) stated that A1c may be added to fasting plasma glucose (FPG) and oral glucose tolerance test (OGTT) as an option for diabetes screening and diagnosis. For monitoring purposes, an A1c of less than 7% indicates good glucose control and a lower risk of diabetic complications for the majority of diabetics. However, in 2012, the ADA and the European Association for the Study of Diabetes (EASD) issued a position statement recommending that the management of glucose control in type 2 diabetes be more "patient-centered." Data from recent studies have shown that low blood sugar (hypoglycemia) can cause complications and that people with risk of severe hypoglycemia, underlying health conditions, complications, and a limited life expectancy do not necessarily benefit from having a stringent goal of less than 7% for their A1c. The statement recommends that people work closely with their doctor to select a goal that reflects each person's individual health status and that balances risks and benefits.

Also known as: Insulin Response to Glucose 4 Specimens

Insulin, Specimen 1

Insulin, Specimen 2

Insulin, Specimen 3

Insulin, Specimen 4

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The Advanced Blood Sugar Monitoring - Advanced panel contains 5 tests with 14 biomarkers.

Brief Description: The Advanced Blood Sugar Monitoring - Advanced panel provides an in-depth analysis of blood sugar regulation, insulin function, and potential autoimmune aspects of diabetes. This comprehensive panel includes Adiponectin, a 4 Specimens Glucose Tolerance Test, Glutamic Acid Decarboxylase-65 Antibody, Hemoglobin A1c, and a 4 Specimens Insulin Response to Glucose test.

Collection Method: Blood Draw

Specimen Type: Whole Blood, Plasma, and Serum

Test Preparation: Overnight fasting required. No food or beverage other than water for at least 8 hours before specimen collection.

High carbohydrate diet for 3 days before specimen collection

When and Why the Advanced Blood Sugar Monitoring - Advanced Panel May Be Ordered

This panel is particularly useful for individuals with a history of glucose intolerance, those at risk of developing diabetes, or individuals with a known diagnosis of diabetes who need detailed monitoring. It's also beneficial for assessing the risk of Type 1 diabetes due to the inclusion of autoimmune antibodies.

What the Advanced Blood Sugar Monitoring - Advanced Panel Checks For

  • Adiponectin: A hormone linked to glucose regulation and fatty acid breakdown. Low levels are associated with insulin resistance and Type 2 diabetes.

  • 4 Specimens Glucose Tolerance Test: Evaluates the body's ability to process glucose over time, identifying potential glucose intolerance or diabetes.

  • Glutamic Acid Decarboxylase-65 Antibody: Detects antibodies associated with autoimmune diabetes, offering insights into the autoimmune etiology of diabetes.

  • Hemoglobin A1c: Provides an overview of average blood glucose control over the past 2-3 months, essential for diabetes management.

  • 4 Specimens Insulin Response to Glucose: Assesses insulin production and function in response to glucose intake, crucial for understanding insulin resistance and diabetes.

Getting a Deeper Understanding of Your Blood Sugar

For those seeking the most thorough evaluation, the Advanced Blood Sugar Monitoring - Comprehensive panel expands upon the Advanced panel by adding:

  • 5 Specimens Glucose Tolerance Test: Provides an additional data point for even more detailed glucose metabolism analysis.

  • IA-2 Antibody: Another marker for autoimmune diabetes, enhancing the assessment of Type 1 diabetes risk.

  • Proinsulin: Measures levels of proinsulin, a precursor to insulin, offering insights into beta-cell function and insulin production.

This comprehensive panel offers the most extensive insights into glucose metabolism, insulin function, and autoimmune diabetes markers, ideal for individuals requiring detailed monitoring or those with complex diabetes management needs.

Conditions or Diseases the Advanced Blood Sugar Monitoring - Advanced Panel Can Check For

This panel is instrumental in diagnosing and managing both Type 1 and Type 2 diabetes, assessing insulin resistance, and monitoring glucose tolerance. The inclusion of autoimmune antibodies also aids in identifying autoimmune diabetes.

Use of Advanced Blood Sugar Monitoring - Advanced Panel Results by Healthcare Professionals

Healthcare professionals use the results to diagnose diabetes, differentiate between Type 1 and Type 2 diabetes, assess insulin function and resistance, and tailor treatment plans for managing diabetes, considering both metabolic and autoimmune components.

The Advanced Blood Sugar Monitoring - Advanced panel offers a comprehensive assessment of blood sugar control, insulin response, and autoimmune diabetes markers, making it a valuable tool for in-depth diabetes evaluation and management. For those needing the utmost detail in their diabetes monitoring, the Comprehensive panel provides an even more extensive analysis, ensuring that all aspects of glucose metabolism and diabetes risk are thoroughly evaluated.

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.

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