Men's Hormone Health

Men’s hormone health tests evaluate the hormones that drive energy, mood, libido, muscle and bone strength, fertility, and metabolic health. Imbalances can stem from the testes (testicular causes), the pituitary/hypothalamus (central causes), the thyroid, or the adrenal glands—and they often overlap with cardiometabolic risks like diabetes and high cholesterol.

A proactive plan usually starts with morning total testosterone and a core health screen (CBC, CMP, lipids, A1c, TSH). Depending on results and symptoms, add free testosterone/SHBGLH/FSHprolactinestradiol (sensitive assay)DHEA-S, and cortisol to clarify the picture. Testing supports screening (when risk or symptoms are present), diagnostic work-up (pinpointing primary vs. central causes), and monitoring over time. Lab results inform next steps but do notreplace a clinician’s exam, shared decision-making, or imaging when indicated.

Signs, Symptoms & Related Situations

  • Sexual & reproductive: low libido, erectile difficulties, fewer morning erections, fertility concerns

  • Energy & mood: fatigue, low motivation, depressed mood, brain fog, poor sleep

  • Body composition: increased body fat, decreased muscle mass/strength, reduced shaving frequency, gynecomastia

  • Thyroid/adrenal clues: cold intolerance, hair thinning, palpitations, heat intolerance, salt cravings, dizziness on standing

  • Metabolic context: central weight gain, high blood pressure, abnormal lipids, elevated fasting glucose or A1c

  • Medication/lifestyle factors: opioids, steroids, androgen-suppressing drugs, heavy alcohol use, sleep apnea

  • Seek urgent care now: chest pain, severe shortness of breath, sudden weakness or vision changes, priapism(erection >4 hours), acute testicular pain

Symptoms and risks should be reviewed by a qualified clinician.

Why These Tests Matter

What testing can do

  • Confirm or rule in endocrine contributors to symptoms (low total or free testosterone; abnormal LH/FSH; high prolactin; thyroid or adrenal imbalance)

  • Differentiate causes (primary testicular vs. central pituitary/hypothalamic patterns)

  • Reveal cardiometabolic risks that commonly track with hormone issues (insulin resistance, atherogenic lipids)

What testing cannot do

  • Diagnose by one value alone or replace a full clinical evaluation

  • Determine psychological or relationship factors contributing to symptoms

  • Provide treatment or dosing advice; results must be interpreted with your clinician

What These Tests Measure (at a glance)

  • Total Testosterone (morning): first-line screen; repeat on a morning sample to confirm low or borderline values.

  • Free Testosterone & SHBG: estimate bioavailable testosterone; useful when total T is borderline or SHBG is altered by age, thyroid, liver disease, or obesity.

  • LH & FSH: high with low T → primary testicular issue; low/normal with low T → central(pituitary/hypothalamic) pattern.

  • Prolactin: elevations can suppress gonadotropins and libido; persistent high results require clinician review.

  • Estradiol (sensitive assay): context for gynecomastia, water retention, or symptoms during therapy decisions.

  • DHEA-S: adrenal androgen status; helps when symptoms suggest adrenal contribution.

  • Thyroid Panel (TSH ± Free T4): thyroid disorders can mimic or worsen hormone-related symptoms.

  • Cortisol (AM) ± ACTH (as directed): screens for adrenal under- or over-activity in selected cases.

  • IGF-1 (select cases): growth hormone axis context when clinically indicated.

  • Core health markers: A1c/fasting glucoselipid panel (± ApoB, Lp[a])CMPCBCVitamin DFerritin/Iron/B12 for fatigue or anemia context.

Quick Build Guide

Goal Start with Add if needed
Hormone wellness baseline AM Total T • TSH • A1c • Lipid panel • CMP • CBC Free T/SHBG • LH/FSH • Prolactin
Suspected Low T AM Total T (repeat if low/borderline) Free T/SHBG • LH/FSH • Prolactin • Estradiol (sensitive)
Low libido/ED, unclear cause AM Total T • TSH • A1c • Lipids Free T/SHBG • Prolactin • LH/FSH
Fertility priority AM Total T • LH/FSH • Prolactin Semen analysis (see Men’s Fertility)
Thyroid-type symptoms TSH Free T4 • Thyroid antibodies (per clinician)
Adrenal-type symptoms AM Cortisol ACTH • DHEA-S (clinician-directed)
Metabolic risk present A1c • Lipids • CMP ApoB • Lp(a) • Vitamin D

How the Testing Process Works

  1. Time your draws: schedule morning testing for testosterone (typically 7–10 a.m.).

  2. Prepare as directed: fasting is required only if your order includes fasting lipids or glucose.

  3. Provide samples: standard blood draw (and semen collection if ordered via Men’s Fertility).

  4. Confirm borderline results: repeat AM total testosterone and add free T/SHBG and LH/FSH to localize the cause.

  5. Review & plan: discuss results with your clinician; set monitoring intervals and consider imaging or specialty referral if needed.

Interpreting Results (General Guidance)

  • Total T low/borderline: repeat in the morning; interpret with free T/SHBG. Use LH/FSH to distinguish primary vs. central patterns.

  • Prolactin elevated: may reduce testosterone and libido—confirm and evaluate with your clinician.

  • TSH abnormal: thyroid imbalance can drive fatigue, weight change, and libido issues.

  • Estradiol or DHEA-S off-range: interpret in context (assay type, age, symptoms).

  • A1c/lipids elevated: cardiometabolic risks often coexist and may worsen symptoms.
    Ranges differ by lab; trends and clinical context matter more than one value.

Choosing Panels vs. Individual Tests

  • Foundational hormone panel: AM Total T • Free T/SHBG • LH/FSH • Prolactin • TSH

  • Expanded hormone insight: Estradiol (sensitive) • DHEA-S • AM Cortisol (± ACTH)

  • Whole-health add-ons: A1c • Lipids (± ApoB, Lp[a]) • CMP • CBC • Vitamin D • Ferritin/Iron/B12
    Choose bundled panels for efficiency and consistent trending; add individual tests to answer specific questions.

FAQs

Do I have to test testosterone in the morning?
Yes. Testosterone follows a daily rhythm; morning testing improves accuracy. Repeat a low result.

Do I need to fast?
Only if your order includes fasting lipids or fasting glucose. Hormone assays typically don’t require fasting.

Is one low testosterone result enough?
No. Clinicians usually confirm with a repeat morning test and add free T/SHBG and LH/FSH.

Can exercise or illness affect results?
Intense exercise, acute illness, poor sleep, and alcohol can shift some values. Aim for a steady state before testing.

Will these tests diagnose the cause by themselves?
They clarify patterns (primary vs. central; thyroid/adrenal overlap), but a clinician’s exam and history remain essential.

Does therapy for hormones affect fertility?
Some therapies can suppress sperm production. Discuss family-building plans with your clinician before starting any treatment.

Are home kits equivalent to lab draws?
Venous lab testing generally offers broader panels and validated methods. Use the same method for reliable trends.

Related Test Categories and Key Tests

  • Men’s Health Tests Hub

  • Low T and Testosterone Replacement Therapy (TRT) • Erectile Dysfunction (ED) Tests • Fertility Test for Men • Prostate Health • Thyroid Tests • Diabetes Health • Heart & Cardiovascular Risk

  • Key Tests: Total Testosterone (AM) • Free Testosterone • SHBG • LH • FSH • Prolactin • Estradiol (sensitive) • DHEA-S • TSH • Free T4 • AM Cortisol • ACTH (as directed) • IGF-1 (select cases) • A1c • Lipid Panel (± ApoB, Lp[a]) • CMP • CBC • Vitamin D • Ferritin • Iron/TIBC • Transferrin Saturation • Vitamin B12

References

  • Endocrine Society — Testosterone Therapy in Men with Hypogonadism: Clinical Practice Guideline.
  • American Urological Association — Testosterone Deficiency and Erectile Dysfunction guidelines.
  • American Thyroid Association — Thyroid Function Testing Guidance.
  • American Association of Clinical Endocrinology — Hypogonadism and endocrine evaluation recommendations.
  • American Diabetes Association — Standards of Care in Diabetes (A1c and metabolic risk).
  • American College of Cardiology/American Heart Association — Cholesterol guideline and risk assessment.
  • Clinical reviews on men’s hormone testing (assay timing, free T methods, SHBG effects).

Available Tests & Panels

Your Men’s Hormone Health Tests menu is pre-populated in the Ulta Lab Tests system. Start with AM total testosteroneTSHA1clipidsCMP, and CBC. Use filters to add free T/SHBGLH/FSHprolactinestradiol (sensitive)DHEA-S, and AM cortisol as needed. Follow any collection instructions and review results with your clinician to confirm findings and set a monitoring plan.

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Are you a male in your early 40s or 50s? Have you noticed that things are wearing you out now that didn't before?

Maybe your memory isn't what it used to be. Or maybe your sexual performance has taken a dive recently.

Well, don't be so quick to chalk those things up to just getting older. You could be one of up to 40% of American men suffering from male hormone imbalance and not even know it! The only way to know for sure is to get a male hormone test.

So, what exactly are male hormones, and what would a hormone test involve? Keep reading to find out!

What Are Male Hormones?

Generally speaking, hormones are your body's chemical messengers. The Greek word means "setting in motion." So, they get things going, biologically speaking.

And when people refer to "male hormones," they're usually talking about a chemical called testosterone. There are others, though, and their levels are also tested during a hormone panel. Testosterone is a steroid hormone, which means that it's an organic compound composed of four rings of carbon atoms.

Testosterone is produced in both men and women. In men, testosterone is primarily produced in the testicles and is responsible (either wholly or partly) for:

  • The development of the male genitalia while in the womb
  • The deepening of the voice during puberty
  • The growth of facial and pubic hair (beginning at puberty)
  • The growth of muscle mass
  • Muscle strength
  • Bone growth and density
  • Sex drive (libido)
  • The production of sperm
  • Verbal memory
  • Cognitive function

Too much testosterone, however, can lead to:

  • Unprovoked or excessive aggression
  • Hardening of the blood vessels
  • Increased levels of cholesterol
  • Prostate problems

About Male Hormone Imbalance

The endocrine system comprises several different glands that produce a myriad of hormones. Dysfunction in any of these can cause a hormonal imbalance, and the four types that most commonly affect males are as follows. 

Andropause

This is the most common type of male hormone imbalance. "Andro" is Greek for "man," while "pause" indicates that a process is coming to a halt. It's called this due to its loose resemblance to menopause in women, and it is often referred to as "male menopause." However, its official name is late-onset hypogonadism.

Adrenal Fatigue

A stress reaction triggers the production of cortisol, which is a stress hormone. Cortisol is produced in your adrenal gland, and being overexposed to it for extended periods of time can lead to things like anxiety, depression, heart disease, and digestive problems.

Hypothyroidism

Your thyroid gland produces two hormones: triiodothyronine and thyroxine. "Hypo" denotes that there isn't enough of something. In this case, the thyroid gland isn't producing enough of those hormones, leading to chronic fatigue, weight gain, and sensitivity to cold temperatures.

Hyperthyroidism

As opposed to the above, "hyper" indicates that the thyroid glands are producing too much of their hormones. This leads to symptoms like rapid weight loss, difficulty sleeping, hyperactivity, and sensitivity to heat.

Risk Factors

Because the production of male hormones begins to steadily taper after the age of 20, aging is one of the main causes of hormone imbalance. A man's growth hormone production tends to drop to around 50% by the age of 40.

But simply getting older isn't the only culprit behind low testosterone. Other factors include:

  • Low levels of activity
  • Calorie-restricted and low-fat diets
  • Genetics
  • Physical injury to the testicles
  • Certain medications like long-acting opioids, ketoconazole, cimetidine, spironolactone, some antidepressants, chemotherapy drugs, and some statins
  • Stress
  • Lack of sleep
  • Excessive consumption of alcohol
  • Smoking
  • Low self-esteem
  • Depression
  • Anxiety

Signs or Symptoms

The following telltale indicators of hormonal imbalance in a man are also common signs of aging. That's why it's so important that you carry out a male hormone imbalance test.

  • Decreased cognitive function
  • Depression
  • Fatigue
  • Insomnia
  • Hair loss
  • Loss of muscle mass
  • Erectile dysfunction
  • Low sex drive (loss of libido)
  • Memory loss
  • Weight gain
  • Mood swings
  • An increase in fat accumulation in the belly and/or chest (gynecomastia or "man boobs")

Laboratory Tests for Male Hormone Imbalance

When seeking to diagnose a hormonal imbalance, it is standard practice to carry out hormone panel testing. This is done to establish a baseline for the levels of all your hormones, which can then be compared against acceptable ranges.

After assessing the following hormones, your health care provider can develop a replacement or supplement plan tailored to your specific needs. This will be intended to restore your body's hormone balance.

  • DHEA: A precursor to testosterone and progesterone produced in the adrenal glands; too much or too little can unbalance the levels of male and female hormones in the body
  • Follicle-stimulating hormone (FSH): A hormone responsible for the production of sperm; low levels can lead to infertility
  • Androstenedione: A weak androgen that is also a precursor to both male and female hormones; if levels of this hormone are not monitored during therapy, excess estrogen can be produced (essentially defeating the purpose)
  • Testosterone: The androgen responsible for male characteristics; a precursor to DHT
  • Dihydrotestosterone (DHT): A very powerful androgen; excess levels can result in hair thinning/loss and prostate enlargement
  • Progesterone: A female sex hormone that serves the purpose of checking the effects of DHT in males
  • Estradiol: A strong estrogen, which is another female hormone; plays a role in regulating the libido, erectile dysfunction, and sperm production
  • Estrone: A weaker estrogen produced in fat cells

Frequently Asked Questions

Because we fear what we don't know, medical issues can cause a lot of trepidation, especially with the issue of male hormone imbalance. To put your mind at ease, here are the answers to some of the most commonly asked questions about low testosterone. 

How Is Low Testosterone Treated?

Male hormonal imbalance is most commonly treated with a hormone replacement therapy called testosterone replacement therapy (TRT). This is essentially intended to boost testosterone levels by supplementing your body's lagging production of it.

What Are the Possible Side Effects of TRT?

In some cases, TRT can worsen sleep apnea, cause acne or other skin conditions, enlarge the prostate, feed the growth of prostate cancer, enlarge the breasts, reduce sperm count, or cause the testicles to shrink. The increased production of red blood cells that TRT causes can also lead to the formation of blood clots.

What Are the Benefits of Balancing Testosterone Levels? 

Among the many benefits of TRT are:

  • Improved libido
  • Improved sexual performance
  • Lower levels of bad cholesterol (LDLs)
  • Increased muscle mass and strength
  • Decreased body fat
  • More confidence and a better mood
  • Higher energy levels during the day
  • Better quality of sleep
  • Improved brain function and cognitive ability
  • Improved regulation of blood sugar, which leads to a decreased risk of diabetes

Where Can I Get a Male Hormone Test?

A male hormone test can be expensive, and the process can be a hassle. But at Ulta Lab Tests, we've gone out of our way to make the process affordable and convenient.

All of our tests are accurate and reliable. The results of your hormone panel test will be returned to you within 24 to 48 hours, so you can start making informed decisions that allow you to take charge of your own health. 

You won't need insurance or a referral. Tests are affordable, and the doctor's order will be included in the price!

Take control of your health today with a male hormone test from Ulta Lab Tests.