Animal Dander Allergy Tests

Animal dander allergy occurs when your immune system makes IgE antibodies to proteins from pets and other animals—most often cats, dogs, rodents (mouse/rat), rabbits, horses, and some birds. These proteins ride on skin flakes (dander), saliva, and urine and can persist indoors long after an animal leaves. A proactive plan starts with allergen-specific IgE (sIgE) blood tests to likely culprits (cat/dog) and expands to other animals based on exposure (home, school/lab, farm/stables). When results or history are mixed, component-resolved diagnostics (CRD)—for example, 

Fel d 1 (cat) and Can f 1–6 (dog)—help separate true sensitization from cross-reactivity and refine counseling.
sIgE requires a routine blood draw and, unlike skin testing, is not blocked by antihistamines. Use results with your clinician to align findings with symptoms and exposure.

Signs, Symptoms & Related Situations

  • Nose/eyes: sneezing, runny or stuffy nose, itchy/watery eyes

  • Chest: cough, wheeze, chest tightness—worse indoors or near animals

  • Skin: hives or itchy rash after contact; eczema flares with pet handling

  • Exposure clues: home pets; classrooms/labs (mouse/rat); barns/stables (horse); small mammals (rabbit/guinea pig); bird cages/feather bedding

  • Urgent care: breathing trouble or facial swelling—seek immediate help
    All symptoms should be evaluated by a qualified clinician.

Why These Tests Matter

What testing can do

  • Confirm sensitization to specific animals with targeted sIgE

  • Clarify cross-reactivity using components (lipocalins, albumins, kallikrein)

  • Support monitoring over time and inform exposure-reduction steps

What testing cannot do

  • Predict exact severity (IgE levels reflect likelihood, not intensity)

  • Replace clinician-directed skin testing or challenge when needed for complex cases

  • Provide treatment advice on its own—use with clinical guidance

Test Numbers at a Glance (sIgE and Components)

  • Cat Dander (e1) IgE — Test 2601Reflex to Cat Components — Test 10564 (Fel d 1 [e94], Fel d 2 [e220], Fel d 4 [e228], Fel d 7 [e231]).

  • Dog Dander (e5) IgE — Test 2605Reflex to Dog Components — Test 10571 (Can f 1 [e101], Can f 2 [e102], Can f 3 [e221], Can f 4 [e229], Can f 5 [e226], Can f 6 [e230]).

  • Mouse IgE (e88) — Test 2611Rat IgE (e87) — Test 2538Rat Epithelia (e73) — Test 2659.

  • Horse Dander (e3) IgE — Test 2603Horse Dander w/Reflex to Equ c 1 (e227) — Test 10629.

  • Rabbit Epithelia (e82) — Test 2654Rabbit (hair) options vary (availability by service area).

  • Bird/Feather selections: Feather Mix (chicken/duck/goose/turkey) — Test 37508Canary Feathers (e201) — Test 2542Pigeon Feathers (e215) — Test 2616.

  • Total IgE (context only) — Test 542.

Component patterns matter: Fel d 1 positivity supports true cat sensitization; Can f 1–6 patterns refine dog risk; isolated albumin positivity can reflect mammalian cross-reactivity. Panel reflexes typically trigger at ≥0.10 kU/L for the whole-dander test.

How the Testing Process Works

  1. Map exposures: list pets and settings (home, school/lab, barn/stable).

  2. Order targeted tests: begin with Cat (2601/10564) and Dog (2605/10571); add Mouse (2611), Rat (2538 or 2659), Horse (2603/10629), Rabbit (2654), Bird/Feather (e.g., 37508/2542/2616) as exposure indicates.

  3. Collect: routine blood draw—no antihistamine hold needed for sIgE.

  4. Results: view securely online in a few days.

  5. Next steps: review with your clinician to align findings with symptoms and environment.

Interpreting Results (General Guidance)

  • Positive specific IgE consistent with exposure and symptoms supports clinical allergy.

  • Component-positive (Fel d 1; selected Can f markers) strengthens evidence for true pet sensitization; albumin-only findings suggest possible mammalian cross-reactivity.

  • Low/borderline sIgE can still be meaningful if symptoms are strong with exposure; your clinician may add skin testing or more components.

  • Negative sIgE with a convincing history may prompt evaluation for non-IgE triggers or other indoor allergens.

Choosing Panels vs. Individual Tests

  • Pet-owner start: Cat (2601 ± 10564) and Dog (2605 ± 10571)

  • Occupational/academic labs: Mouse (2611) and Rat (2538 or 2659); add Rabbit (2654) if present

  • Equestrian exposure: Horse (2603 ± 10629)

  • Bird/feather bedding: Feather Mix (37508); consider specific bird feathers (25422616) and dust-mite testing if pillows/comforters are used

  • Clarify cross-reactivity: add components (Fel d 1; Can f 1–6) when dander sIgE is positive but history is mixed

FAQs

Do I need to stop antihistamines before these blood tests?
No. Antihistamines do not affect sIgE blood testing (they can affect skin tests).

Does a higher IgE mean a worse reaction?
Not necessarily. Higher levels increase likelihood of reactivity but don’t measure severity.

Why order components like Fel d 1 or Can f 1–6?
Components help separate true pet sensitization from cross-reactivity, improving counseling.

Can I be allergic to one dog but not another?
Yes. Dogs carry multiple allergen families; component patterns and exposure levels matter more than breed.

If the pet leaves, will results turn negative?
sIgE may persist for months or years; symptoms often improve sooner with reduced exposure.

Blood vs skin tests—what’s the difference?
sIgE blood is medication-friendly and standardized; skin testing can be more sensitive for some allergens and is clinician-performed.

Internal Links & Cross-References

  • Allergy Testing Hub

  • Environmental Allergies • Dust Mite • Mold • Pollen (Trees/Grasses/Weeds) • Food Allergy Testing (IgE) • Allergy Components

  • Downward (individual test pages): Cat sIgE 2601 (± Cat Components 10564) • Dog sIgE 2605 (± Dog Components 10571) • Mouse sIgE 2611 • Rat sIgE 2538/2659 • Horse sIgE 2603 (± Component Reflex 10629) • Rabbit sIgE 2654 • Feather Mix 37508 • Canary 2542 • Pigeon 2616 • Total IgE 542

References

  1. Component testing for furry animal allergies—topic brief (content reviewed 2024).

  2. Respiratory Allergy Panel test details showing reflex to cat and dog component panels and reflex threshold.

  3. Individual test details for Cat (2601/10564), Dog (2605/10571), Mouse (2611), Rat (2538/2659), Horse (2603/10629), Rabbit (2654), Feather Mix (37508), Canary (2542), Pigeon (2616), Total IgE (542).

Available Tests & Panels

Your animal dander allergy menu is pre-populated in the Ulta Lab Tests system. Use filters to select single-allergen sIgE(e.g., 2601260526112538/2659260326543750825422616), add component testing (Fel d 1; Can f 1–6 via 10564/10571) when cross-reactivity is suspected, and include Total IgE (542) for context. Schedule a local blood draw and review results with your clinician to align testing with symptoms and exposures.

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Name Matches

The Sheep Sorrel w18 IgE Test measures IgE antibodies to allergens from sheep sorrel pollen. Elevated levels may indicate an allergic reaction, which can cause hay fever symptoms such as sneezing, runny nose, itchy eyes, or asthma flare-ups during pollen season. This test helps identify sheep sorrel pollen allergies and supports management through avoidance strategies or allergy treatments guided by healthcare providers.

Blood
Blood Draw
Also Known As: Sheep Sorrel IgE Test, Sheep Sorrel w16 Test

The Swine Epithelia e83 IgE Test measures IgE antibodies to proteins from pig skin and fur. Elevated levels may indicate an allergic reaction, which can cause nasal congestion, sneezing, itchy eyes, skin irritation, or asthma in sensitive individuals. This test helps identify swine epithelium allergies and supports management through avoidance strategies or allergy treatments guided by healthcare providers.

Blood
Blood Draw
Also Known As: Swine Epithelia IgE Test, Swine Epithelia e83 Test

The Turkey Feathers e89 IgE Test measures IgE antibodies to proteins in turkey feathers. Elevated levels may indicate an allergic reaction, which can cause symptoms such as sneezing, nasal congestion, itchy eyes, skin irritation, or asthma. This test helps identify turkey feather allergies and supports management through avoidance strategies or allergy treatments guided by healthcare providers.

Blood
Blood Draw
Also Known As: Turkey Feathers IgE Test, Turkey Feathers e89 Test

The Cat Dander e1 and Dog Dander e5 IgE Test Panel measures IgE antibodies to cat and dog dander proteins. Elevated levels suggest an allergic response that may cause sneezing, runny nose, itchy eyes, asthma, or skin reactions. This panel helps identify pet-related allergies and supports management strategies such as avoidance, treatment, or environmental control.

Blood
Blood Draw
Panel Contains Test: Dog and Cat Dander IgE Test, Dog e5 and Cat e1 Test

Did you know that 30% of Americans are allergic to animals? With such a large percentage of pet allergies, you'd think that there wouldn't be so many misconceptions about animal pet dander. 

We are here to set the facts straight about allergic reactions, pet dander, and pet allergy tests. 

Keep reading to learn more!

What are Pet Allergies?

Pet allergies are often associated with the hair and fur that make our fluffy friends so adorable. This is not the case! Pet allergies are a reaction due to animal skin cells, saliva, and urine, which contain a specific protein that causes us to sniffle. 

Dead flakes of skin called dander cause most allergic reactions. You can have allergic reactions to all sorts of animals, but cats and dogs are the most common, most likely because they are the most common animals we interact with. 

Our immune system plays a critical role in keeping us healthy and alive. Its job is to find and fight foreign substances. These substances can include viruses, bacteria, or small particles such as dead skin cells, dust, or hair. 

An allergic reaction is when an immune system reacts to harmless particles such as animal dander. As the immune system fights these particles, your body starts to exhibit symptoms that are similar to colds and other viruses.

Animal allergies can get worse with frequent exposure. So if you suspect that you have an animal dander allergy, make sure you take a pet allergy test to confirm. 

Risk Factors for Animal Dander Allergy

Many signs and symptoms are minor and simply annoying when it comes to animal allergic reactions. However, there are some major risk factors if the allergic reaction is severe. 

The reaction can include anything from a runny nose to sneezing, to more severe reactions like difficulty breathing, chest tightness, audible wheezing, or trouble sleeping caused by shortness of breath. When you are experiencing these symptoms, remove yourself from the situation and follow up with a doctor. 

You can also develop a sinus infection or asthma if you are continuously exposed to the animal you are allergic to. 

What Are the Signs and Symptoms of Pet Allergies?

Most allergic reactions are caused by the dander landing on your eyes and nose. When you are allergic, these areas will swell and itch when you are in close proximity to the animal you are allergic to. 

Often times the dead skin cells, or dander, are small enough to enter the lungs. As a result, those with a history of asthma or sensitive lungs can experience severe breathing problems. In addition, these problems can lead to a severe allergic reaction if not managed properly. 

Animal allergies do not only affect the respiratory system. They can also affect your skin. This is called allergic dermatitis, which is an immune reaction causing inflammation. 

These symptoms can include hives, eczema, and itchy skin. 

As mentioned before, pets are not the only cause of allergic reactions. Many people are allergic to different types of animals. We may not even know which animals since we rarely come in contact with them. The symptoms are the same, however. 

So, if you are visiting a friend's farm and suddenly start sneezing and coughing, you might be allergic to the cattle, ducks, or mice that live in the barn. 

How is Animal Dander Allergy Diagnosed?

The doctor will go over your symptoms, medical history, and conduct a physical examination to determine whether you are allergic to certain animals. When you visit the doctor, they will also order several lab tests to confirm the diagnosis.

What Are the Different Types of Pet Allergy Tests?

Since the immune system fights harmful and harmless particles in a similar manner, it is important to confirm what it is fighting. 

That is why pet allergy tests are crucial to determining what is ailing us. The doctor will order several tests, including blood tests (IgE), intradermal skin tests, or in some cases, usually with allergic dermatitis, patch tests.

An IgE test is an allergen blood test collected by a phlebotomist at a patient service center and sent to a national testing lab. At Ulta Lab Tests, we offer several IgE tests that are accurate and affordable, and you don’t need health insurance or a doctor’s referral to order them.

We offer 100's of allergy tests, including the following animal allergy tests.

  • Canary Bird Feathers (e201) IgE
  • Cat Dander (e1) IgE
  • Chicken Feathers (e85) IgE
  • Cow Dander (e4) IgE
  • Dog Danger (e5) IgE
  • Duck Feathers (e86) IgE
  • Ferret Epithelium (e217) IgE
  • Finch Feathers (re214) IgE
  • Gerbil (e209) IgE
  • Goat Epithelia (e80) IgE
  • Goose Feathers (e70) IgE
  • Hamster Epithelia (e84) IgE
  • Horse Dander (e88) IgE
  • Parrot/Parakeet Feathers (e78) IgE
  • Pigeon Feathers (e215) IgE
  • Rat (e87) IgE
  • Sheep Epithelia (e81) IgE
  • Swine Epithelia (e83) IgE
  • Turkey Feathers (e89) IgE

With an intradermal test, the doctor or nurse will inject a small amount of the suspected allergen under your skin. If the area swells up and becomes inflamed, you are likely allergic to that specific animal. A doctor may still suspect an allergy even if the skin does not swell. 

Lastly, a patch test is used when a skin allergy is suspected. For example, if your new kitten is causing rashes and itchy skin, you may have allergic dermatitis. Instead of injecting the skin as with the intradermal test, the doctor will place a tiny amount of allergen on your skin. If you are allergic, you will develop a rash in that area.

Are You Allergic to Animal Dander?

Allergies are no fun. Whether you are allergic to pets, cattle, or other fluffy friends, allergies are frustrating. If you suspect that you are allergic, don't hesitate to order a pet test allergy. 

Are you interested in more lab tests that are secure and confidential, affordable, and don't need an insurance referral? 

Ulta Lab Tests offers highly accurate and reliable tests with a 100% satisfaction guarantee so that you can make informed decisions about your health. 

Order your pet allergy lab test today, and your results will be provided to you securely and confidentially online in 24 to 48 hours for most tests. Take control of your health today with Ulta Lab Tests.