Ulta Lab Tests

Weight Loss Resistance & Metabolism - Essential Lab Panel

The Weight Loss Resistance & Metabolism Essential Lab Panel includes 12 tests and 71 biomarkers to review stubborn weight loss, slow metabolism, insulin resistance, blood sugar, thyroid function, inflammation, cholesterol, liver health, nutrient status, and metabolic wellness. It includes CBC, CMP, A1c, insulin, lipid panel, TSH, Free T4, hs-CRP, ferritin, vitamin D, magnesium, and uric acid to support a focused first-step metabolic health review.

Blood, Serum
Phlebotomist

Weight Loss Essential Panel, Metabolism Lab Panel, Insulin Resistance Panel, Slow Metabolism Blood Test, Weight Loss Blood Test, Metabolic Health Panel, Stubborn Weight Loss Panel

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: CBC, CBC includes Differential and Platelets, CBC/PLT w/DIFF, Complete Blood Count (includes Differential and Platelets)

NOTE: Ulta Lab Tests provides CBC test results from Quest Diagnostics as they are reported. Often, different biomarker results are made available at different time intervals. When reporting the results, Ulta Lab Tests denotes those biomarkers not yet reported as 'pending' for every biomarker the test might report. Only biomarkers Quest Diagnostics observes are incorporated and represented in the final CBC test results provided by Ulta Lab Tests.

Absolute Band Neutrophils (Only Reported If Detected)

Immature forms of neutrophils are called neutrophilic band cells. Neutrophils are a type of white blood cell that is responsible for much of the body's protection against infection. Neutrophils are produced in the bone marrow and released into the bloodstream to travel to wherever they are needed. Large numbers of immature forms of neutrophils, called neutrophilic band cells, are produced by the bone marrow when the demand is high.

Absolute Basophils

Basophils normally constitute 1% or less of the total white blood cell count but may increase or decrease in certain diseases and are thought to be involved in allergic reactions.

Absolute Blasts (Only Reported If Detected)

Blasts are immature forms of white blood cells.

Absolute Eosinophils

Eosinophils (eos) respond to infections caused by parasites and play a role in allergic reactions (hypersensitivities)

Absolute Lymphocytes

Lymphocytes are white blood cells that exist in both the blood and the lymphatic system. They are divided into three types. The B lymphocytes (B cells) are antibody-producing cells that are essential for acquired, antigen-specific immune responses. The second type are T lymphocytes (T cells) some T cells help the body distinguish between "self" and "non-self" antigens while others initiate and control the extent of an immune response, boosting it as needed and then slowing it as the condition resolves. Other types of T cells directly attack and neutralize virus-infected or cancerous cells. The third type are natural killer cells (NK cells) that directly attack and kill abnormal cells such as cancer cells or those infected with a virus.

Absolute Metamyelocytes (Only Reported If Detected)

Metamyelocytes are immature forms of white blood cells.

Absolute Monocytes

Monocytes (mono), similar to neutrophils, move to an area of infection and engulf and destroy bacteria. They are associated more often with chronic rather than acute infections. They are also involved in tissue repair and other functions involving the immune system.

Absolute Myelocytes (Only Reported If Detected)

Myelocytes are immature forms of white blood cells.

Absolute Neutrophils

Neutrophils (neu) normally make up the largest number of circulating WBCs. They move into an area of damaged or infected tissue, where they engulf and destroy bacteria or sometimes fungi. Young neutrophils, recently released into circulation, are called bands.

Absolute Nucleated Rbc (Only Reported If Detected)

Nucleated Red Blood Cells (nRBC) ) the presence of NRBCs in the adult blood is usually associated with malignant neoplasms, bone marrow diseases, and other serious disorders.

Absolute Promyelocytes (Only Reported If Detected)

Promyelocytes are immature forms of white blood cells.

Band Neutrophils (Only Reported If Detected)

Immature forms of neutrophils are called neutrophilic band cells. Neutrophils are a type of white blood cell that is responsible for much of the body's protection against infection. Neutrophils are produced in the bone marrow and released into the bloodstream to travel to wherever they are needed. Large numbers of immature forms of neutrophils, called neutrophilic band cells, are produced by the bone marrow when the demand is high.

Basophils

Basophils normally constitute 1% or less of the total white blood cell count but may increase or decrease in certain diseases and are thought to be involved in allergic reactions.

Blasts (Only Reported If Detected)

Blasts are immature forms of white blood cells.

Eosinophils

Eosinophils are specialized white blood cells produced in the bone marrow and released into the bloodstream, where they normally make up only 0–6 % of circulating leukocytes. Their cytoplasm is packed with reddish‑orange granules that contain potent enzymes (e.g., major basic protein, eosinophil cationic protein) and inflammatory mediators. When the immune system detects large, multicellular invaders—such as helminth (worm) parasites—eosinophils migrate out of the blood and surround the pathogen, releasing these granule contents to damage the parasite’s outer surface and aid its destruction. Beyond parasite defense, eosinophils act as key orchestras of the allergic response. They accumulate in tissues exposed to allergens (airways in asthma, skin in eczema, GI tract in eosinophilic esophagitis) and secrete cytokines and lipid mediators that amplify inflammation, recruit additional immune cells, and contribute to symptoms like swelling, mucus production, and itching. Because of this pro‑inflammatory role, persistently elevated eosinophil counts—termed eosinophilia—can signal allergic disorders, drug hypersensitivity, or certain autoimmune and malignant conditions. Conversely, counts drop toward zero after glucocorticoid therapy or in acute stress states, reflecting the cells’ sensitivity to hormonal and immune regulation.

Hematocrit

Hematocrit is a blood test that measures the percentage of the volume of whole blood that is made up of red blood cells. This measurement depends on the number of red blood cells and the size of red blood cells.

Hemoglobin

Serum hemoglobin is a blood test that measures the level of free hemoglobin in the liquid part of the blood (the serum). Free hemoglobin is the hemoglobin outside of the red blood cells. Most of the hemoglobin is found inside the red blood cells, not in the serum.

Lymphocytes

Lymphocytes are white blood cells that exist in both the blood and the lymphatic system. They are divided into three types. The B lymphocytes (B cells) are antibody-producing cells that are essential for acquired, antigen-specific immune responses. The second type are T lymphocytes (T cells) some T cells help the body distinguish between "self" and "non-self" antigens while others initiate and control the extent of an immune response, boosting it as needed and then slowing it as the condition resolves. Other types of T cells directly attack and neutralize virus-infected or cancerous cells. The third type are natural killer cells (NK cells) that directly attack and kill abnormal cells such as cancer cells or those infected with a virus.

MCH

Mean corpuscular hemoglobin (MCH) is a calculation of the average amount of oxygen-carrying hemoglobin inside a red blood cell.

MCHC

Mean corpuscular hemoglobin concentration (MCHC) is a calculation of the average percentage of hemoglobin inside a red cell.

MCV

Mean corpuscular volume (MCV) is a measurement of the average size of RBCs.

Metamyelocytes (Only Reported If Detected)

Metamyelocytes are immature forms of white blood cells.

Monocytes

Monocytes (mono), similar to neutrophils, move to an area of infection and engulf and destroy bacteria. They are associated more often with chronic rather than acute infections. They are also involved in tissue repair and other functions involving the immune system.

MPV

Mean Platelet Volume (MPV) - When it indicates average size of platelets are small; older platelets are generally smaller than younger ones and a low MPV may mean that a condition is affecting the production of platelets by the bone marrow. When it indicates a high number of larger, younger platelets in the blood; this may be due to the bone marrow producing and releasing platelets rapidly into circulation.

Myelocytes (Only Reported If Detected)

Myelocytes are immature forms of white blood cells.

Neutrophils

Neutrophils are a type of white blood cell that is responsible for much of the body's protection against infection. Neutrophils are produced in the bone marrow and released into the bloodstream to travel to wherever they are needed.

Nucleated Rbc (Only Reported If Detected)

Nucleated Red Blood Cells (nRBC) ) the presence of NRBCs in the adult blood is usually associated with malignant neoplasms, bone marrow diseases, and other serious disorders.

Platelet Count

A platelet count is a test to measure how many platelets you have in your blood. Platelets help the blood clot. They are smaller than red or white blood cells.

Promyelocytes (Only Reported If Detected)

Promyelocytes are immature forms of white blood cells.

RDW

Red cell distribution width (RDW), which may be included in a CBC, is a calculation of the variation in the size of RBCs.

Reactive Lymphocytes (Only Reported If Detected)

Lymphocytes are white blood cells that exist in both the blood and the lymphatic system. They are divided into three types. The B lymphocytes (B cells) are antibody-producing cells that are essential for acquired, antigen-specific immune responses. The second type are T lymphocytes (T cells) some T cells help the body distinguish between "self" and "non-self" antigens while others initiate and control the extent of an immune response, boosting it as needed and then slowing it as the condition resolves. Other types of T cells directly attack and neutralize virus-infected or cancerous cells. The third type are natural killer cells (NK cells) that directly attack and kill abnormal cells such as cancer cells or those infected with a virus.

Red Blood Cell Count

An RBC count is a blood test that tells how many red blood cells (RBCs) you have. RBCs contain hemoglobin, which carries oxygen. How much oxygen your body tissues get depends on how many RBCs you have and how well they work.

White Blood Cell Count

A WBC count is a test to measure the number of white blood cells (WBCs) in the blood. WBCs help fight infections. They are also called leukocytes. There are five major types of white blood cells: basophils, eosinophils, lymphocytes (T cells and B cells), monocytes and neutrophils

Also known as: Chem 12, Chemistry Panel, Chemistry Screen, CMP, Complete Metabolic Panel, Comprehensive Metabolic Panel CMP, SMA 12, SMA 20

Albumin

Albumin is a protein made by the liver. A serum albumin test measures the amount of this protein in the clear liquid portion of the blood.

Albumin/Globulin Ratio

The ratio of albumin to globulin (A/G ratio) is calculated from measured albumin and calculated globulin (total protein - albumin). Normally, there is a little more albumin than globulins, giving a normal A/G ratio of slightly over 1. Because disease states affect the relative amounts of albumin and globulin, the A/G ratio may provide a clue as to the cause of the change in protein levels. A low A/G ratio may reflect overproduction of globulins, such as seen in multiple myeloma or autoimmune diseases, or underproduction of albumin, such as may occur with cirrhosis, or selective loss of albumin from the circulation, as may occur with kidney disease (nephrotic syndrome). A high A/G ratio suggests underproduction of immunoglobulins as may be seen in some genetic deficiencies and in some leukemias. More specific tests, such as liver enzyme tests and serum protein electrophoresis, must be performed to make an accurate diagnosis. With a low total protein that is due to plasma expansion (dilution of the blood), the A/G ratio will typically be normal because both albumin and globulin will be diluted to the same extent.

Alkaline Phosphatase

Alkaline phosphatase (ALP) is a protein found in all body tissues. Tissues with higher amounts of ALP include the liver, bile ducts, and bone.

Alt

Alanine transaminase (ALT) is an enzyme found in the highest amounts in the liver. Injury to the liver results in release of the substance into the blood.

AST

AST (aspartate aminotransferase) is an enzyme found in high amounts in liver, heart, and muscle cells. It is also found in lesser amounts in other tissues.

Bilirubin, Total

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Bun/Creatinine Ratio

A ratio between a person’s BUN and blood creatinine to help determine what is causing these concentrations to be higher than normal. The ratio of BUN to creatinine is usually between 10:1 and 20:1. An increased ratio may be due to a condition that causes a decrease in the flow of blood to the kidneys, such as congestive heart failure or dehydration. It may also be seen with increased protein, from gastrointestinal bleeding, or increased protein in the diet. The ratio may be decreased with liver disease (due to decrease in the formation of urea) and malnutrition.

Calcium

You have more calcium in your body than any other mineral. Calcium has many important jobs. The body stores more than 99 percent of its calcium in the bones and teeth to help make and keep them strong. The rest is throughout the body in blood, muscle and the fluid between cells. Your body needs calcium to help muscles and blood vessels contract and expand, to secrete hormones and enzymes and to send messages through the nervous system.

Carbon Dioxide

CO2 is carbon dioxide. Measures the amount of carbon dioxide in the liquid part of your blood, called the serum. In the body, most of the CO2 is in the form of a substance called bicarbonate (HCO3-). Therefore, the CO2 blood test is really a measure of your blood bicarbonate level.

Chloride

Chloride is a type of electrolyte. It works with other electrolytes such as potassium, sodium, and carbon dioxide (CO2). These substances help keep the proper balance of body fluids and maintain the body's acid-base balance. This is a measure of the amount of chloride in the fluid portion (serum) of the blood.

Creatinine

The creatinine blood test measures the level of creatinine in the blood. This test is done to see how well your kidneys work.

Egfr African American

Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

Egfr Non-Afr. American

Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

GFR-AFRICAN AMERICAN

GFR-NON AFRICAN AMERICAN

Globulin

Globulins is the collective term for most blood proteins other than albumin. Identifying the types of globulins can help diagnose certain disorders. Globulins are roughly divided into three groups: alpha, beta, and gamma globulins. Gamma globulines include various types of antibodies such as immunoglobulins (Ig) M, G, and A.

Glucose

A blood glucose test measures the amount of a sugar called glucose in a sample of your blood. Glucose is a major source of energy for most cells of the body, including those in the brain. The hormones insulin and glucagon help control blood glucose levels.

Potassium

Potassium is a mineral that the body needs to work normally. It helps nerves and muscles communicate. It also helps move nutrients into cells and waste products out of cells. A diet rich in potassium helps to offset some of sodium's harmful effects on blood pressure.

Protein, Total

The total protein is the total amount of two classes of proteins, albumin and globulin that are found in the fluid portion of your blood. Proteins are important parts of all cells and tissues. Your albumin helps prevent fluid from leaking out of blood vessels and your globulins are an important part of your immune system.

Sodium

Sodium is a substance that the body needs to work properly it is vital to normal body processes, including nerve and muscle function

Urea Nitrogen (Bun)

BUN stands for blood urea nitrogen. Urea nitrogen is what forms when protein breaks down. BUN measures the amount of urea nitrogen in the blood.

Ferritin

Ferritin is a protein found inside cells that stores iron so your body can use it later. A ferritin test indirectly measures the amount of iron in your blood. The amount of ferritin in your blood (serum ferritin level) is directly related to the amount of iron stored in your body.

Also known as: A1c, Glycated Hemoglobin, Glycohemoglobin, Glycosylated Hemoglobin, HA1c, HbA1c, Hemoglobin A1c, Hemoglobin A1c HgbA1C, Hgb A1c

HEMOGLOBIN A1C

The A1c test evaluates the average amount of glucose in the blood over the last 2 to 3 months. It does this by measuring the concentration of glycated (also often called glycosylated) hemoglobin A1c. Hemoglobin is an oxygen-transporting protein found inside red blood cells (RBCs). There are several types of normal hemoglobin, but the predominant form – about 95-98% – is hemoglobin A. As glucose circulates in the blood, some of it spontaneously binds to hemoglobin A. The hemoglobin molecules with attached glucose are called glycated hemoglobin. The higher the concentration of glucose in the blood, the more glycated hemoglobin is formed. Once the glucose binds to the hemoglobin, it remains there for the life of the red blood cell – normally about 120 days. The predominant form of glycated hemoglobin is referred to as HbA1c or A1c. A1c is produced on a daily basis and slowly cleared from the blood as older RBCs die and younger RBCs (with non-glycated hemoglobin) take their place. This test is used to monitor treatment in someone who has been diagnosed with diabetes. It helps to evaluate how well their glucose levels have been controlled by treatment over time. This test may be used to screen for and diagnose diabetes or risk of developing diabetes. In 2010, clinical practice guidelines from the American Diabetes Association (ADA) stated that A1c may be added to fasting plasma glucose (FPG) and oral glucose tolerance test (OGTT) as an option for diabetes screening and diagnosis. For monitoring purposes, an A1c of less than 7% indicates good glucose control and a lower risk of diabetic complications for the majority of diabetics. However, in 2012, the ADA and the European Association for the Study of Diabetes (EASD) issued a position statement recommending that the management of glucose control in type 2 diabetes be more "patient-centered." Data from recent studies have shown that low blood sugar (hypoglycemia) can cause complications and that people with risk of severe hypoglycemia, underlying health conditions, complications, and a limited life expectancy do not necessarily benefit from having a stringent goal of less than 7% for their A1c. The statement recommends that people work closely with their doctor to select a goal that reflects each person's individual health status and that balances risks and benefits.

Also known as: C-Reactive Protein, Cardio CRP, Cardio hs-CRP, CRP, High Sensitivity CRP, High-sensitivity C-reactive Protein, High-sensitivity CRP, Highly Sensitive CRP, hsCRP, Ultra-sensitive CRP

Hs Crp

A high-sensitivity CRP (hs-CRP) test may be used by itself, in combination with other cardiac risk markers, or in combination with a lipoprotein-associated phospholipase A2 (Lp-PLA2) test that evaluates vascular inflammation. The hs-CRP test accurately detects low concentrations of C-reactive protein to help predict a healthy person's risk of cardiovascular disease (CVD). High-sensitivity CRP is promoted by some as a test for determining a person's risk level for CVD, heart attacks, and strokes. The current thinking is that hs-CRP can play a role in the evaluation process before a person develops one of these health problems.

Also known as: Insulin (fasting)

Insulin

Insulin is a hormone that is produced and stored in the beta cells of the pancreas. It is vital for the transportation and storage of glucose at the cellular level, helps regulate blood glucose levels, and has a role in lipid metabolism. When blood glucose levels rise after a meal, insulin is released to allow glucose to move into tissue cells, especially muscle and adipose (fat) cells, where is it is used for energy production. Insulin then prompts the liver to either store the remaining excess blood glucose as glycogen for short-term energy storage and/or to use it to produce fatty acids. The fatty acids are eventually used by adipose tissue to synthesize triglycerides to form the basis of a longer term, more concentrated form of energy storage. Without insulin, glucose cannot reach most of the body's cells. Without glucose, the cells starve and blood glucose levels rise to unhealthy levels. This can cause disturbances in normal metabolic processes that result in various disorders, including kidney disease, cardiovascular disease, and vision and neurological problems. Thus, diabetes, a disorder associated with decreased insulin effects, is eventually a life-threatening condition.

Also known as: Cholesterol, HDL,Fasting Lipids,Cholesterol, LDL, Fasting Lipids, Lipid Panel (fasting), Lipid Profile (fasting), Lipids

Chol/HDLC Ratio

Cholesterol, Total

Cholesterol is a waxy, fat-like substance that occurs naturally in all parts of the body. Your body needs some cholesterol to work properly. But if you have too much in your blood, it can combine with other substances in the blood and stick to the walls of your arteries. This is called plaque. Plaque can narrow your arteries or even block them. High levels of cholesterol in the blood can increase your risk of heart disease. Your cholesterol levels tend to rise as you get older. There are usually no signs or symptoms that you have high blood cholesterol, but it can be detected with a blood test. You are likely to have high cholesterol if members of your family have it, if you are overweight or if you eat a lot of fatty foods. You can lower your cholesterol by exercising more and eating more fruits and vegetables. You also may need to take medicine to lower your cholesterol.

HDL Cholesterol

LDL-Cholesterol

Non HDL Cholesterol

Triglycerides

Triglycerides are a form of fat and a major source of energy for the body. This test measures the amount of triglycerides in the blood. Most triglycerides are found in fat (adipose) tissue, but some triglycerides circulate in the blood to provide fuel for muscles to work. After a person eats, an increased level of triglycerides is found in the blood as the body converts the energy not needed right away into fat. Triglycerides move via the blood from the gut to adipose tissue for storage. In between meals, triglycerides are released from fat tissue to be used as an energy source for the body. Most triglycerides are carried in the blood by lipoproteins called very low density lipoproteins (VLDL). High levels of triglycerides in the blood are associated with an increased risk of developing cardiovascular disease (CVD), although the reason for this is not well understood. Certain factors can contribute to high triglyceride levels and to risk of CVD, including lack of exercise, being overweight, smoking cigarettes, consuming excess alcohol, and medical conditions such as diabetes and kidney disease.

Magnesium

Vitamin D, 25-Oh, D2

Vitamin D2 ((ergocalciferol,) is found in fortified foods and in most vitamin preparations and supplements. Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. The D2 form is found in fortified foods and in most vitamin preparations and supplements. Vitamin D2 is effective when it is converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Vitamin D, 25-Oh, D3

Vitamin D3 (cholecalcifero) which comes from animals. Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. Vitamin D3 is the form produced in the body and is also used in some supplements. Vitamin D3 are is converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Vitamin D, 25-Oh, Total

Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. The chemical structures of the types of vitamin D are slightly different, and they are named vitamin D2 (ergocalciferol, which comes from plants) and vitamin D3 (cholecalciferol, which comes from animals). The D2 form is found in fortified foods and in most vitamin preparations and supplements. Vitamin D3 is the form produced in the body and is also used in some supplements. Vitamin D2 and D3 are equally effective when they are converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Also known as: Free T4, FT4, T4 Free

T4, Free

The free T4 test is not affected by protein levels. Since free T4 is the active form of thyroxine, the free T4 test is may be a more accurate reflection of thyroid hormone function.

Also known as: Thyroid Stimulating Hormone Test, Thyrotropin Test

TSH

A TSH test is a lab test that measures the amount of thyroid stimulating hormone (TSH) in your blood. TSH is produced by the pituitary gland. It tells the thyroid gland to make and release thyroid hormones into the blood.

Also known as: Serum Urate, UA

Uric Acid

Uric acid is a chemical created when the body breaks down substances called purines. Purines are found in some foods and drinks. These include liver, anchovies, mackerel, dried beans and peas, and beer. Most uric acid dissolves in blood and travels to the kidneys. From there, it passes out in urine. If your body produces too much uric acid or doesn't remove enough if it, you can get sick. A high level of uric acid in the blood is called hyperuricemia.
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The Weight Loss Resistance & Metabolism - Essential Lab Panel panel contains 12 tests with 71 biomarkers .

Overview

The Weight Loss Resistance & Metabolism Essential Lab Panel is designed for people who want a focused lab-based starting point to evaluate common biomarker patterns that may be related to stubborn weight loss, slow metabolism, belly fat, cravings, fatigue, energy crashes, insulin resistance, thyroid symptoms, inflammation, cholesterol concerns, and metabolic wellness.

Weight loss resistance can involve several overlapping systems, including blood sugar regulation, insulin response, thyroid function, liver function, inflammation, cholesterol metabolism, nutrient status, uric acid patterns, and general metabolic health.

This Essential panel focuses on foundational tests often reviewed when weight loss feels difficult despite diet, exercise, lifestyle changes, or weight-management efforts. It includes CBC, CMP, Hemoglobin A1c, insulin, lipid panel, TSH, Free T4, hs-CRP, ferritin, vitamin D, magnesium, and uric acid.

This panel does not diagnose the cause of weight-loss resistance by itself. Results should be reviewed with a licensed healthcare provider and interpreted with symptoms, diet, activity level, sleep, stress, medications, supplements, hormone status, weight history, and medical history.

Why Order This Panel?

The Weight Loss Resistance & Metabolism Essential Lab Panel may be helpful for people who want a practical first-step review of common metabolic, thyroid, inflammatory, and nutrient-related markers that may influence weight management.

This panel may help provide insight into:

  • Blood sugar patterns
  • Insulin resistance
  • Thyroid function
  • Cholesterol and triglyceride patterns
  • Low-grade inflammation
  • Liver, kidney, electrolyte, calcium, albumin, and protein markers
  • Iron storage and inflammation-related ferritin patterns
  • Vitamin D status
  • Magnesium status
  • Uric acid and metabolic stress patterns
  • General blood health and metabolic wellness

This panel is a strong starting point for people who want a focused metabolism and weight-loss resistance evaluation before choosing a broader Advanced or Comprehensive panel.

This Panel May Be Helpful For People With

  • Stubborn weight loss
  • Slow metabolism concerns
  • Belly fat or increased waist circumference
  • Cravings or frequent hunger
  • Energy crashes after meals
  • Fatigue with weight gain
  • Insulin resistance or prediabetes concerns
  • Thyroid symptoms
  • Cold intolerance or low body temperature
  • High cholesterol or triglycerides
  • Family history of diabetes or heart disease
  • Weight regain after dieting
  • Difficulty losing weight despite diet and exercise
  • Metabolic syndrome risk
  • Inflammation concerns
  • High uric acid, gout, or kidney stone concerns
  • Interest in a focused metabolic baseline

What This Panel Helps Evaluate

This panel helps evaluate selected biomarkers related to:

  • Weight-loss resistance
  • Slow metabolism
  • Blood sugar regulation
  • Insulin resistance
  • Thyroid hormone production
  • Cholesterol and triglycerides
  • Low-grade inflammation
  • Liver and kidney function
  • Electrolyte and metabolic balance
  • Ferritin and iron-storage context
  • Vitamin D status
  • Magnesium status
  • Uric acid and metabolic stress
  • General blood health

Which Tier Is Right for Me?

Essential Lab Panel

The Weight Loss Resistance & Metabolism Essential Lab Panel is best for people who want a focused starting point. It reviews common lab areas related to weight and metabolism, including CBC, CMP, A1c, insulin, lipid panel, TSH, Free T4, hs-CRP, ferritin, vitamin D, magnesium, and uric acid.

Choose Essential if you want a practical first step for weight-loss resistance, blood sugar, thyroid, cholesterol, inflammation, and metabolic health.

Advanced Lab Panel

The Weight Loss Resistance & Metabolism Advanced Lab Panel is best for people who want deeper insight into insulin production, advanced cholesterol risk, thyroid antibodies, liver/bile markers, kidney/urine markers, B vitamins, methylation, and hormone-stress patterns.

Choose Advanced if symptoms are persistent or involve cravings, energy crashes, thyroid symptoms, insulin resistance, hormone changes, stress-related weight gain, fatty liver risk, or cardiometabolic risk.

Comprehensive Lab Panel

The Weight Loss Resistance & Metabolism Comprehensive Lab Panel is the broadest option. It includes the Essential and Advanced categories and may add appetite and fat-cell signaling markers such as leptin and adiponectin, Cardio IQ™ lipoprotein fractionation, OMEGACHECK™, FSH/LH, prolactin, and expanded metabolic and hormone context.

Choose Comprehensive if you want the deepest review of weight-loss resistance, metabolism, appetite hormones, insulin resistance, thyroid function, hormones, inflammation, advanced lipids, kidney risk, liver stress, and nutrient status.

Tests Included and Why They Matter

Blood Sugar, Insulin Resistance & Metabolic Function

Weight-loss resistance often overlaps with insulin resistance, blood sugar instability, cravings, energy crashes, and difficulty using stored fat efficiently. This group helps evaluate how the body handles glucose, insulin, and metabolic fuel.

Hemoglobin A1c

Hemoglobin A1c measures average blood sugar over approximately the past two to three months.

This test is included because long-term blood sugar patterns may provide context for prediabetes risk, diabetes risk, energy crashes, cravings, weight gain, and metabolic health. A1c is especially useful when weight-loss resistance overlaps with fatigue, increased hunger, abdominal weight gain, or family history of diabetes.

Insulin

Insulin helps move glucose from the bloodstream into cells.

This test is included because fasting insulin may provide important context for insulin resistance, one of the most common metabolic patterns associated with stubborn weight loss. Elevated insulin patterns may contribute to cravings, energy crashes, difficulty losing fat, and metabolic slowdown.

Insulin can be useful even when A1c or glucose appears less obvious, because insulin may rise before blood sugar becomes abnormal.

Comprehensive Metabolic Panel, CMP

The CMP evaluates glucose, liver function, kidney function, electrolytes, calcium, albumin, total protein, and other metabolic markers.

This test is included because weight-loss and metabolism review benefits from a broad organ-function baseline. CMP findings may provide context for glucose, liver enzymes, kidney markers, hydration, electrolytes, calcium, protein status, and general metabolic wellness.

Thyroid Function & Metabolic Rate

Thyroid hormones help regulate metabolism, energy production, body temperature, heart rate, bowel function, weight, and cognitive speed. Thyroid patterns can strongly overlap with slow metabolism, fatigue, and weight-loss resistance.

TSH

TSH is a key thyroid screening marker.

This test is included because thyroid function may influence metabolism, energy, weight, mood, body temperature, constipation, hair changes, and mental clarity. TSH provides an important starting point for thyroid-related weight and metabolism review.

TSH is especially useful when weight-loss resistance overlaps with cold intolerance, fatigue, constipation, dry skin, hair thinning, low mood, or low energy.

T4, Free

Free T4 measures the available form of thyroxine, a thyroid hormone.

This test is included because Free T4 provides additional thyroid hormone production context when reviewed with TSH and symptoms. It may be useful when weight-loss resistance overlaps with fatigue, cold intolerance, constipation, dry skin, or low energy.

Together, TSH and Free T4 provide a focused thyroid review for an Essential metabolism panel.

Cholesterol, Triglycerides & Cardiometabolic Risk

Weight-loss resistance, insulin resistance, inflammation, thyroid function, and genetics can all affect cholesterol and triglyceride patterns. This group provides core cardiometabolic risk context.

Lipid Panel

The Lipid Panel measures total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides.

This test is included because lipid patterns provide cardiometabolic context for weight-loss resistance, insulin resistance, metabolic syndrome risk, and long-term cardiovascular wellness.

Triglycerides and HDL can be especially useful when reviewing insulin resistance, abdominal weight gain, diet patterns, and metabolic health.

Inflammation, Ferritin & Metabolic Stress

Low-grade inflammation can contribute to insulin resistance, fatigue, metabolic stress, and difficulty losing weight. Ferritin provides iron-storage context but can also be affected by inflammation and liver-metabolic patterns.

hs-CRP

High-sensitivity C-reactive protein is a marker of low-grade inflammation.

This test is included because inflammation may contribute to insulin resistance, metabolic stress, cardiovascular risk, fatigue, and weight-loss difficulty. hs-CRP also helps interpret ferritin, which may rise with inflammation.

hs-CRP is nonspecific and should be reviewed with symptoms, weight history, body composition, medical history, medications, and other lab findings.

Ferritin

Ferritin measures stored iron.

This test is included because ferritin may provide context for iron storage, fatigue, inflammation, metabolic liver patterns, and general wellness. Ferritin can be low with iron deficiency or elevated with inflammation, liver stress, metabolic issues, or iron overload.

In a metabolism panel, ferritin helps connect fatigue, inflammation, and metabolic stress patterns.

Vitamin D, Magnesium & Nutrient Support

Nutrient status can influence energy, glucose metabolism, muscle function, inflammation balance, blood pressure, and overall metabolic wellness. This group evaluates two common nutrient areas that may overlap with weight-loss resistance.

QuestAssureD™ 25-Hydroxy and 1,25-Dihydroxyvitamin D, LC/MS/MS

This vitamin D panel evaluates vitamin D status using LC/MS/MS methodology.

Vitamin D is included because it supports bone health, immune function, inflammation balance, muscle function, and general metabolic wellness. Low vitamin D may overlap with fatigue, body composition concerns, muscle symptoms, and metabolic risk.

Vitamin D may be especially useful to review in people with limited sun exposure, low vitamin D history, higher body weight, bone concerns, or low energy.

Magnesium

Magnesium supports glucose metabolism, insulin sensitivity, muscle function, blood pressure regulation, sleep, and energy production.

This test is included because magnesium may provide context for metabolic health, muscle symptoms, blood sugar patterns, cravings, blood pressure, sleep quality, and general weight-loss wellness.

Magnesium is especially relevant when weight-loss resistance overlaps with cramps, fatigue, poor sleep, blood sugar concerns, or metabolic risk.

Uric Acid & Metabolic Syndrome Context

Uric acid can overlap with insulin resistance, metabolic syndrome, high-fructose intake, kidney stone risk, gout risk, and cardiometabolic stress.

Uric Acid

Uric acid is a metabolic waste product.

This test is included because uric acid may provide context for metabolic syndrome, insulin resistance, gout risk, kidney stone risk, high-protein diets, fructose intake, and cardiometabolic stress.

In a weight-loss resistance panel, uric acid adds useful metabolic context, especially when abdominal weight gain, high blood pressure, insulin resistance, gout, or kidney stone history are present.

Blood Health & General Wellness

A broad metabolic panel benefits from basic blood health context because fatigue, inflammation, anemia patterns, and platelet changes can influence energy, wellness, and interpretation of other results.

CBC, includes Differential and Platelets

The CBC evaluates red blood cells, white blood cells, hemoglobin, hematocrit, platelets, and white blood cell types.

This test is included because weight-loss resistance and fatigue can overlap with anemia-related patterns, inflammation clues, immune patterns, platelet changes, and general blood health. It provides a foundational wellness marker for broader metabolic interpretation.

Related Biomarker Patterns This Panel May Help Identify

This panel may help identify or rule out lab patterns related to:

  • Insulin resistance
  • Blood sugar imbalance
  • Prediabetes or diabetes risk patterns
  • Slow thyroid function patterns
  • Abnormal cholesterol or triglyceride patterns
  • Low-grade inflammation
  • Ferritin and metabolic stress patterns
  • Vitamin D status
  • Magnesium status
  • Uric acid elevation
  • Liver or kidney marker changes
  • Electrolyte or hydration patterns
  • General cardiometabolic wellness patterns

Professional Safety and Interpretation Notice

This panel is designed to support weight-loss resistance and metabolism evaluation. It does not diagnose obesity, insulin resistance, thyroid disease, cardiovascular disease, fatty liver disease, kidney disease, metabolic syndrome, or any condition by itself.

Results should be interpreted with a licensed healthcare provider and reviewed alongside symptoms, weight history, diet, physical activity, sleep, stress, medications, supplements, hormone status, menstrual or menopause status, family history, and health goals.

Do not stop or change any prescribed medication or supplement without guidance from your healthcare provider.

How to Prepare for This Panel

Preparation may vary depending on the specific tests and instructions provided with your order. In general:

  • Fasting may be recommended because insulin, glucose, and lipid markers are included.
  • Bring a list of medications, supplements, GLP-1 medications, thyroid medications, hormone products, and doses.
  • Note symptoms such as cravings, fatigue, energy crashes, weight changes, sleep issues, stress, and exercise tolerance.
  • For women, note menstrual cycle timing, perimenopause or menopause status, and hormone therapy use.
  • Drink water normally unless instructed otherwise.
  • Follow all lab collection instructions provided with your order.

What Happens After You Receive Your Results?

After your results are available, your biomarkers can help organize weight-loss and metabolism findings into areas such as blood sugar, insulin resistance, thyroid function, cholesterol, inflammation, vitamin D, magnesium, uric acid, liver function, kidney function, and general metabolic wellness.

During the physician consultation, you can discuss whether your results suggest the need for follow-up testing, medication review, nutrition changes, exercise adjustments, thyroid review, cardiometabolic risk management, or additional clinical care.

Additional Panels to Consider

Customers interested in the Weight Loss Resistance & Metabolism Essential Lab Panel may also consider:

  • Weight Loss Resistance & Metabolism Advanced Lab Panel
  • Weight Loss Resistance & Metabolism Comprehensive Lab Panel
  • Prediabetes & Insulin Resistance Lab Panel
  • Thyroid & Metabolism Lab Panel
  • Fatigue, Low Energy & Brain Fog Lab Panel
  • Heart Health & Cholesterol Lab Panel
  • Stress, Cortisol, Sleep & Burnout Lab Panel
  • Women’s Hormone Balance & Perimenopause Lab Panel
  • Men’s Testosterone, Energy & Vitality Lab Panel
  • GLP-1 Medication Safety Lab Panel
  • Longevity & Healthy Aging Lab Panel

FAQ: Weight Loss Resistance & Metabolism Essential Lab Panel

What is the Weight Loss Resistance & Metabolism Essential Lab Panel?

The Weight Loss Resistance & Metabolism Essential Lab Panel is a focused blood test panel that evaluates biomarkers related to weight-loss resistance, metabolism, insulin resistance, blood sugar, thyroid function, cholesterol, inflammation, vitamin D, magnesium, uric acid, and general metabolic wellness.

What blood tests are commonly reviewed for weight-loss resistance?

Common weight-loss and metabolism labs may include Hemoglobin A1c, fasting insulin, CMP, lipid panel, TSH, Free T4, hs-CRP, ferritin, vitamin D, magnesium, uric acid, and CBC. This Essential panel includes those foundational markers.

Does this panel help evaluate insulin resistance?

Yes. This panel includes Hemoglobin A1c, insulin, CMP glucose, triglycerides from the Lipid Panel, and uric acid. Together, these markers may provide useful context for insulin resistance and metabolic risk.

Why are thyroid markers included?

Thyroid function can affect metabolism, energy, weight, body temperature, bowel patterns, hair, skin, and mood. This panel includes TSH and Free T4 for a focused thyroid review.

Why are cholesterol and triglycerides included?

Cholesterol and triglyceride patterns can provide cardiometabolic context. Triglycerides and HDL patterns may be useful when weight-loss resistance overlaps with insulin resistance or metabolic syndrome risk.

Why is hs-CRP included?

hs-CRP is a marker of low-grade inflammation. Inflammation may overlap with insulin resistance, metabolic stress, cardiometabolic risk, fatigue, and difficulty losing weight.

Why is uric acid included?

Uric acid may provide context for metabolic syndrome, insulin resistance, gout risk, kidney stone risk, high-protein diets, fructose intake, and cardiometabolic stress.

Can this panel diagnose why I cannot lose weight?

No. This panel does not diagnose the cause of weight-loss resistance by itself. It helps evaluate selected biomarkers that may be useful to review with a licensed healthcare provider.

Is this panel useful for people taking GLP-1 medications?

This panel may provide useful metabolic and cardiometabolic context for people using GLP-1 medications, but customers specifically focused on GLP-1 safety monitoring may also consider the GLP-1 Medication Safety Lab Panel.

Should I choose Essential, Advanced, or Comprehensive?

Choose Essential for a focused weight-loss metabolism baseline, Advanced for deeper insulin, thyroid, hormone, liver, kidney, and cardiometabolic testing, and Comprehensive for the broadest review of insulin resistance, appetite hormones, advanced lipids, thyroid, hormones, inflammation, omega status, and nutrient markers.

Important Note

This panel is designed to help evaluate selected biomarkers that may be related to weight-loss resistance, metabolism, insulin resistance, blood sugar, thyroid function, inflammation, cholesterol, vitamin D, magnesium, uric acid, liver function, kidney function, and cardiometabolic wellness. It is not intended to diagnose, treat, cure, or prevent disease by itself. Results should be reviewed with a licensed healthcare provider.

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