UltaNutrient™ Comprehensive Nutrient & Metabolic Panel

The UltaNutrient™ Comprehensive Nutrient & Metabolic Panel combines extensive vitamin and mineral testing with a full Comprehensive Metabolic Panel and functional biomarkers. Measuring iron metabolism, magnesium (serum and RBC), trace minerals, vitamins A, B6, B12, D, E, folate (serum and RBC), homocysteine, MMA, hs-CRP, and electrolytes, this panel delivers an integrated view of nutrient utilization and metabolic health.

Serum, Plasma-Unspecified Vial Pour, Blood, Other
Phlebotomist

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Chem 12, Chemistry Panel, Chemistry Screen, CMP, Complete Metabolic Panel, Comprehensive Metabolic Panel CMP, SMA 12, SMA 20

Albumin

Albumin is a protein made by the liver. A serum albumin test measures the amount of this protein in the clear liquid portion of the blood.

Albumin/Globulin Ratio

The ratio of albumin to globulin (A/G ratio) is calculated from measured albumin and calculated globulin (total protein - albumin). Normally, there is a little more albumin than globulins, giving a normal A/G ratio of slightly over 1. Because disease states affect the relative amounts of albumin and globulin, the A/G ratio may provide a clue as to the cause of the change in protein levels. A low A/G ratio may reflect overproduction of globulins, such as seen in multiple myeloma or autoimmune diseases, or underproduction of albumin, such as may occur with cirrhosis, or selective loss of albumin from the circulation, as may occur with kidney disease (nephrotic syndrome). A high A/G ratio suggests underproduction of immunoglobulins as may be seen in some genetic deficiencies and in some leukemias. More specific tests, such as liver enzyme tests and serum protein electrophoresis, must be performed to make an accurate diagnosis. With a low total protein that is due to plasma expansion (dilution of the blood), the A/G ratio will typically be normal because both albumin and globulin will be diluted to the same extent.

Alkaline Phosphatase

Alkaline phosphatase (ALP) is a protein found in all body tissues. Tissues with higher amounts of ALP include the liver, bile ducts, and bone.

Alt

Alanine transaminase (ALT) is an enzyme found in the highest amounts in the liver. Injury to the liver results in release of the substance into the blood.

AST

AST (aspartate aminotransferase) is an enzyme found in high amounts in liver, heart, and muscle cells. It is also found in lesser amounts in other tissues.

Bilirubin, Total

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Bun/Creatinine Ratio

A ratio between a person’s BUN and blood creatinine to help determine what is causing these concentrations to be higher than normal. The ratio of BUN to creatinine is usually between 10:1 and 20:1. An increased ratio may be due to a condition that causes a decrease in the flow of blood to the kidneys, such as congestive heart failure or dehydration. It may also be seen with increased protein, from gastrointestinal bleeding, or increased protein in the diet. The ratio may be decreased with liver disease (due to decrease in the formation of urea) and malnutrition.

Calcium

You have more calcium in your body than any other mineral. Calcium has many important jobs. The body stores more than 99 percent of its calcium in the bones and teeth to help make and keep them strong. The rest is throughout the body in blood, muscle and the fluid between cells. Your body needs calcium to help muscles and blood vessels contract and expand, to secrete hormones and enzymes and to send messages through the nervous system.

Carbon Dioxide

CO2 is carbon dioxide. Measures the amount of carbon dioxide in the liquid part of your blood, called the serum. In the body, most of the CO2 is in the form of a substance called bicarbonate (HCO3-). Therefore, the CO2 blood test is really a measure of your blood bicarbonate level.

Chloride

Chloride is a type of electrolyte. It works with other electrolytes such as potassium, sodium, and carbon dioxide (CO2). These substances help keep the proper balance of body fluids and maintain the body's acid-base balance. This is a measure of the amount of chloride in the fluid portion (serum) of the blood.

Creatinine

The creatinine blood test measures the level of creatinine in the blood. This test is done to see how well your kidneys work.

Egfr African American

Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

Egfr Non-Afr. American

Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

GFR-AFRICAN AMERICAN

GFR-NON AFRICAN AMERICAN

Globulin

Globulins is the collective term for most blood proteins other than albumin. Identifying the types of globulins can help diagnose certain disorders. Globulins are roughly divided into three groups: alpha, beta, and gamma globulins. Gamma globulines include various types of antibodies such as immunoglobulins (Ig) M, G, and A.

Glucose

A blood glucose test measures the amount of a sugar called glucose in a sample of your blood. Glucose is a major source of energy for most cells of the body, including those in the brain. The hormones insulin and glucagon help control blood glucose levels.

Potassium

Potassium is a mineral that the body needs to work normally. It helps nerves and muscles communicate. It also helps move nutrients into cells and waste products out of cells. A diet rich in potassium helps to offset some of sodium's harmful effects on blood pressure.

Protein, Total

The total protein is the total amount of two classes of proteins, albumin and globulin that are found in the fluid portion of your blood. Proteins are important parts of all cells and tissues. Your albumin helps prevent fluid from leaking out of blood vessels and your globulins are an important part of your immune system.

Sodium

Sodium is a substance that the body needs to work properly it is vital to normal body processes, including nerve and muscle function

Urea Nitrogen (Bun)

BUN stands for blood urea nitrogen. Urea nitrogen is what forms when protein breaks down. BUN measures the amount of urea nitrogen in the blood.

Copper

Carbon Dioxide

CO2 is carbon dioxide. Measures the amount of carbon dioxide in the liquid part of your blood, called the serum. In the body, most of the CO2 is in the form of a substance called bicarbonate (HCO3-). Therefore, the CO2 blood test is really a measure of your blood bicarbonate level.

Chloride

Chloride is a type of electrolyte. It works with other electrolytes such as potassium, sodium, and carbon dioxide (CO2). These substances help keep the proper balance of body fluids and maintain the body's acid-base balance. This is a measure of the amount of chloride in the fluid portion (serum) of the blood.

Potassium

Potassium is a mineral that the body needs to work normally. It helps nerves and muscles communicate. It also helps move nutrients into cells and waste products out of cells. A diet rich in potassium helps to offset some of sodium's harmful effects on blood pressure.

Sodium

Sodium is a substance that the body needs to work properly it is vital to normal body processes, including nerve and muscle function

Ferritin

Ferritin is a protein found inside cells that stores iron so your body can use it later. A ferritin test indirectly measures the amount of iron in your blood. The amount of ferritin in your blood (serum ferritin level) is directly related to the amount of iron stored in your body.

Also known as: Folate RBC, Folic Acid, Red Cell Folate

Folate, Rbc

Also known as: Homocysteine, Homocysteine Cardiovascular

HOMOCYSTEINE,

Also known as: C-Reactive Protein, Cardio CRP, Cardio hs-CRP, CRP, High Sensitivity CRP, High-sensitivity C-reactive Protein, High-sensitivity CRP, Highly Sensitive CRP, hsCRP, Ultra-sensitive CRP

Hs Crp

A high-sensitivity CRP (hs-CRP) test may be used by itself, in combination with other cardiac risk markers, or in combination with a lipoprotein-associated phospholipase A2 (Lp-PLA2) test that evaluates vascular inflammation. The hs-CRP test accurately detects low concentrations of C-reactive protein to help predict a healthy person's risk of cardiovascular disease (CVD). High-sensitivity CRP is promoted by some as a test for determining a person's risk level for CVD, heart attacks, and strokes. The current thinking is that hs-CRP can play a role in the evaluation process before a person develops one of these health problems.

Also known as: Iron and TIBC, Iron and Total Iron Binding Capacity TIBC, TIBC

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Iron Binding Capacity

Total iron binding capacity (TIBC) is a blood test to see if you may have too much or too little iron in the blood. Iron moves through the blood attached to a protein called transferrin. This test helps your doctor know how well that protein can carry iron in the blood.

Iron, Total

Iron is a mineral that our bodies need for many functions. For example, iron is part of hemoglobin, a protein which carries oxygen from our lungs throughout our bodies. It helps our muscles store and use oxygen. Iron is also part of many other proteins and enzymes. Your body needs the right amount of iron. If you have too little iron, you may develop iron deficiency anemia. Causes of low iron levels include blood loss, poor diet, or an inability to absorb enough iron from foods. People at higher risk of having too little iron are young children and women who are pregnant or have periods.

Magnesium

Also known as: Magnesium RBC

Magnesium, Rbc

About half of the body's magnesium is found in bone. The other half is found inside cells of body tissues and organs. Magnesium is needed for nearly all chemical processes in the body. It helps maintain normal muscle and nerve function, and keeps the bones strong. Magnesium is also needed for the heart to function normally and to help regulate blood pressure. Magnesium also helps the body control blood sugar level and helps support the body's defense (immune) system.

Methylmalonic Acid

Also known as: Inorganic Phosphate, P, Phosphate as Phosphorus, Phosphorus, PO4

Phosphate (As Phosphorus)

This test is performed to see how much phosphorus in your blood. Kidney, liver, and certain bone diseases can cause abnormal phosphorus levels.

Vitamin D, 25-Oh, D2

Vitamin D2 ((ergocalciferol,) is found in fortified foods and in most vitamin preparations and supplements. Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. The D2 form is found in fortified foods and in most vitamin preparations and supplements. Vitamin D2 is effective when it is converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Vitamin D, 25-Oh, D3

Vitamin D3 (cholecalcifero) which comes from animals. Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. Vitamin D3 is the form produced in the body and is also used in some supplements. Vitamin D3 are is converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Vitamin D, 25-Oh, Total

Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. The chemical structures of the types of vitamin D are slightly different, and they are named vitamin D2 (ergocalciferol, which comes from plants) and vitamin D3 (cholecalciferol, which comes from animals). The D2 form is found in fortified foods and in most vitamin preparations and supplements. Vitamin D3 is the form produced in the body and is also used in some supplements. Vitamin D2 and D3 are equally effective when they are converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Selenium

Also known as: Receptor, Soluble Transferrin, Transferrin, Receptor Soluble

Soluble Transferrin

Also known as: Retinol, Vitamin A, Vitamin A Retinol

Vitamin A

This test measures the level of retinol in the blood; retinol is the primary form of vitamin A in animals. Vitamin A is an essential nutrient required for healthy vision, skin growth and integrity, bone formation, immune function, and embryonic development. It is required to produce photoreceptors in the eyes and to maintain the lining of the surface of the eyes and other mucous membranes. Deficiencies in vitamin A can impair night vision, cause eye damage, and in severe cases lead to blindness. Acute or chronic excesses of vitamin A can be toxic, cause a range of symptoms, and sometimes lead to birth defects. The body cannot make vitamin A and must rely on dietary sources of vitamin A. Meat sources provide vitamin A (as retinol), while vegetable and fruit sources provide carotene (a substance that can be converted into vitamin A by the liver). Vitamin A is stored in the liver and fat tissues (it is fat-soluble), and healthy adults may have as much as a year's worth stored. The body maintains a relatively stable concentration in the blood through a feedback system that releases vitamin A from storage as needed and increases or decreases the efficiency of dietary vitamin A absorption.

Also known as: Cobalamin, Folic Acid, Vitamin B 12, Vitamin B 12 and Folic Acid, Vitamin B12 Cobalamin and Folate Panel Serum, Vitamin B12/Folic Acid

Folate, Serum

Folate is part of the B complex of vitamins and is measures the levels of folate in the liquid portion of the blood, the serum or plasma, to detect deficiencies. Folate is necessary for normal RBC formation, tissue and cellular repair, and DNA synthesis.. A deficiency inr folate can lead to macrocytic anemia. Megaloblastic anemia, a type of macrocytic anemia, is characterized by the production of fewer but larger RBCs called macrocytes, in addition to some cellular changes in the bone marrow.

Vitamin B12

Vitamin B12 is part of the B complex of vitamins and measurea the levels of vitamin B12 in the liquid portion of the blood, the serum or plasma, to detect deficiencies. Cobalamine, or vitamin B12, is found in animal products such as red meat, fish, poultry, milk, yogurt, and eggs and is not produced in the human body. In recent years, fortified cereals, breads, and other grain products have also become important dietary sources of B12. Vitamin B12 is necessary for normal RBC formation, tissue and cellular repair, and DNA synthesis. B12 is important for nerve health. A deficiency in B12 can lead to macrocytic anemia. Megaloblastic anemia, a type of macrocytic anemia, is characterized by the production of fewer but larger RBCs called macrocytes, in addition to some cellular changes in the bone marrow. B12 deficiency can lead to varying degrees of neuropathy, nerve damage that can cause tingling and numbness in the affected person's hands and feet.

Also known as: B6, B6 Vitamin, Pyridoxal, Pyridoxal Phosphate, Pyridoxal Phosphate (PLP), Vitamin B6 Pyridoxal Phosphate

Vitamin B6

Also known as: Alpha-Tocopherol, Vitamin E Tocopherol

Alpha-Tocopherol

Beta-Gamma-Tocopherol

Also known as: ZN, Plasma

Zinc

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The UltaNutrient™ Comprehensive Nutrient & Metabolic Panel panel contains 20 tests with 49 biomarkers .

The UltaNutrient™ Comprehensive Nutrient & Metabolic Panel is an advanced, integrative laboratory assessment designed to evaluate nutritional status alongside core metabolic function. This panel combines a full Comprehensive Metabolic Panel (CMP) with extensive vitamin, mineral, electrolyte, iron, inflammatory, and functional nutrient biomarkers to provide a multidimensional view of how nutrients and metabolism interact at both the systemic and cellular levels.

While individual nutrient tests can identify isolated deficiencies or excesses, they often lack the metabolic context needed for meaningful interpretation. This panel addresses that gap by layering functional biomarkers—such as homocysteine, methylmalonic acid (MMA), soluble transferrin receptor, RBC folate, and RBC magnesium—alongside traditional serum measurements and metabolic markers. The result is a more complete understanding of nutrient utilization, intracellular balance, inflammation-related demand, and organ-system function.

Micronutrients influence nearly every metabolic pathway, from mitochondrial energy production and red blood cell formation to detoxification, electrolyte regulation, and immune signaling. The inclusion of the CMP allows clinicians and patients to interpret nutrient findings within the broader framework of liver function, kidney function, glucose regulation, protein status, and electrolyte balance. This integrated design supports a functional, systems-based approach to laboratory assessment rather than isolated data points.

The UltaNutrient™ Comprehensive Nutrient & Metabolic Panel is commonly used in preventive health, integrative care, and longitudinal monitoring when a deeper understanding of nutritional foundations and metabolic health is desired. It is particularly valuable when clinical questions extend beyond “Are nutrients present?” to “How effectively are nutrients being utilized within the body?”

When and Why Someone Would Order This Panel

Evaluating Nutrients Within Metabolic Context

This panel is often ordered when a comprehensive assessment is needed that connects nutrient status with metabolic function. By combining micronutrient testing with a CMP, healthcare providers can evaluate how vitamin and mineral levels align with kidney, liver, glucose, and protein metabolism, offering a more complete picture than nutrient testing alone.

Complex or Persistent Laboratory Patterns

Individuals with unexplained laboratory trends, persistent fatigue patterns, metabolic stress indicators, or nutrient-related concerns may benefit from a panel that integrates functional markers such as homocysteine, MMA, and soluble transferrin receptor. These markers can help clarify whether nutrient-related pathways are functioning efficiently at the cellular level.

Dietary Patterns, Absorption, and Utilization

Restrictive diets, plant-based eating patterns, supplementation regimens, and absorption concerns can all influence how nutrients are processed and utilized. Measuring both serum and intracellular markers—such as RBC folate and RBC magnesium—provides additional insight into tissue-level nutrient status beyond circulating concentrations.

Monitoring Iron and Mineral Balance

Iron metabolism is complex and cannot be fully understood through iron levels alone. This panel incorporates ferritin, total iron binding capacity, and soluble transferrin receptor to help characterize iron storage, transport, and cellular demand. Trace minerals such as zinc, copper, selenium, and phosphorus further support evaluation of enzymatic and metabolic balance.

Preventive and Longitudinal Health Monitoring

In preventive and integrative health settings, this panel supports proactive monitoring of nutritional resilience and metabolic efficiency over time. It is well suited for establishing a detailed baseline or tracking trends across multiple physiological systems.

What Does the Panel Measure

Comprehensive Metabolic Function

The Comprehensive Metabolic Panel (CMP) evaluates glucose, kidney markers, liver enzymes, proteins, calcium, and electrolytes, offering foundational insight into metabolic and organ-system function. These results provide essential context for interpreting nutrient and electrolyte findings.

Functional and Inflammatory Biomarkers

Homocysteine reflects methylation efficiency and B-vitamin–dependent pathways. Methylmalonic acid (MMA) is a sensitive functional marker of vitamin B12 utilization. High-sensitivity C-reactive protein (hs-CRP) identifies low-grade systemic inflammation that can increase nutrient demand and influence metabolic efficiency.

Iron and Trace Minerals

Iron metabolism is assessed through iron, ferritin, total iron binding capacity, and soluble transferrin receptor, which together help characterize iron availability, storage, and cellular utilization. Copper, zinc, selenium (serum), and phosphate (as phosphorus) support enzymatic activity, antioxidant defense, bone health, and cellular energy pathways.

Vitamin Status

The panel measures QuestAssureD® Vitamin D 25-Hydroxy Total with D2 and D3, vitamins A and E, vitamin B12, vitamin B6, serum folate, and RBC folate, reflecting antioxidant capacity, neurological support, red blood cell formation, and methylation activity.

Magnesium and Electrolytes

Serum magnesium and RBC magnesium provide complementary insight into circulating and intracellular magnesium stores. Sodium, potassium, chloride, and carbon dioxide (CO2) assess electrolyte balance and acid–base regulation.

How Patients and Healthcare Providers Use the Results

Identifying Integrated Nutrient–Metabolic Patterns

Results from this panel help identify patterns that link nutrient status with metabolic function, inflammation, and cellular efficiency. Providers interpret these markers collectively to understand how nutrients are being absorbed, utilized, and regulated within the body.

Supporting Evaluation of Related Conditions

Healthcare providers may reference this panel when evaluating laboratory patterns associated with anemia-related trends, cardiometabolic risk factors, inflammatory states, neurological concerns, metabolic imbalance, or nutrient-related fatigue patterns.

Guiding Monitoring and Follow-Up

Because this panel integrates both nutrient and metabolic markers, it is particularly valuable for longitudinal tracking. Repeat testing can help assess changes over time in response to dietary adjustments, supplementation strategies, or broader care plans.

Facilitating Informed, Data-Driven Discussions

Rather than serving as a standalone diagnostic tool, the UltaNutrient™ Comprehensive Nutrient & Metabolic Panel provides a robust dataset that supports informed conversations between patients and healthcare providers about next steps, additional testing, or ongoing monitoring strategies.

The UltaNutrient™ Comprehensive Nutrient & Metabolic Panel delivers an expansive, systems-based view of nutritional and metabolic health by integrating micronutrients, functional biomarkers, inflammation markers, iron studies, electrolytes, and comprehensive metabolic data. This layered approach emphasizes context, utilization, and physiological balance rather than isolated laboratory values.

Its strength lies in helping translate complex biochemical information into meaningful patterns that support thoughtful interpretation and continuity of care. Whether used for preventive screening, advanced nutritional evaluation, or long-term monitoring, this panel provides reliable laboratory insight that complements clinical judgment and individualized health planning—without assumptions or transactional framing.

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